Click here to switch to the map view.

The map label for this gene is iorA [H]

Identifier: 220918394

GI number: 220918394

Start: 3672764

End: 3673231

Strand: Reverse

Name: iorA [H]

Synonym: A2cp1_3298

Alternate gene names: 220918394

Gene position: 3673231-3672764 (Counterclockwise)

Preceding gene: 220918395

Following gene: 220918393

Centisome position: 73.04

GC content: 73.08

Gene sequence:

>468_bases
ATGGCCAGCCTGACCCTGCTCGTGAACGACCAGAAGCGCACGGTGGACGTCGCGCCGGAGACGCCGCTGCTGTGGGTGCT
CCGCGACACGCTCGGCCTCACCGGCACGAAGTTCGGCTGCGGCATGTCGCTCTGCGGCGCGTGCACGGTGCTGCTCGACG
GCGACGCGGTGCGGAGCTGCCAGACGCCGGTGAAGGACGCCGTCGGGCACCGCATCACCACGATCGAAGGGCTCGCCGCC
GGCGGCAGCCCGCTGCAGGCGGCGTGGGTGGAGGAGGAGGTCCCGCAGTGCGGGTACTGCCAGTCCGGGCAGATCATGTC
CGCGGCGGCGCTCCTCACCAGGACCCCGGATCCCACCGACGCGCAGATCGACGCCGCCATGGACGGCGTGCTGTGCCGGT
GCGGGACGTACCAGCGGATCCGCCGCGCCATCCACCGCGCGGCGCGGGCCAAGGGAGGTGCGCGATGA

Upstream 100 bases:

>100_bases
ACCTGGTGGCGACGCTGCGCCGCGCGGCCGCGCCCGTCCCGGCGCCCGCCGCCGCCGCGCCCGCCACCTGATCCCGGCCG
CAGGACATGGAGGAGACGAG

Downstream 100 bases:

>100_bases
GCGCCGGGGCGCTGGGGCGAAGGGACTTCCTGAAGCTCTCGGCGGGCGCGGGGCTGTGGCTGGCCGTGTCCGGTCCGGGC
CGCGTGCTGGCCGCGGGGCA

Product: (2Fe-2S)-binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 154

Protein sequence:

>155_residues
MASLTLLVNDQKRTVDVAPETPLLWVLRDTLGLTGTKFGCGMSLCGACTVLLDGDAVRSCQTPVKDAVGHRITTIEGLAA
GGSPLQAAWVEEEVPQCGYCQSGQIMSAAALLTRTPDPTDAQIDAAMDGVLCRCGTYQRIRRAIHRAARAKGGAR

Sequences:

>Translated_155_residues
MASLTLLVNDQKRTVDVAPETPLLWVLRDTLGLTGTKFGCGMSLCGACTVLLDGDAVRSCQTPVKDAVGHRITTIEGLAA
GGSPLQAAWVEEEVPQCGYCQSGQIMSAAALLTRTPDPTDAQIDAAMDGVLCRCGTYQRIRRAIHRAARAKGGAR
>Mature_154_residues
ASLTLLVNDQKRTVDVAPETPLLWVLRDTLGLTGTKFGCGMSLCGACTVLLDGDAVRSCQTPVKDAVGHRITTIEGLAAG
GSPLQAAWVEEEVPQCGYCQSGQIMSAAALLTRTPDPTDAQIDAAMDGVLCRCGTYQRIRRAIHRAARAKGGAR

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=160, Percent_Identity=36.875, Blast_Score=75, Evalue=3e-14,
Organism=Escherichia coli, GI1786480, Length=162, Percent_Identity=41.358024691358, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1789232, Length=148, Percent_Identity=38.5135135135135, Blast_Score=88, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17540638, Length=164, Percent_Identity=35.3658536585366, Blast_Score=100, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI32566215, Length=150, Percent_Identity=36.6666666666667, Blast_Score=100, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17539860, Length=142, Percent_Identity=38.0281690140845, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI17737937, Length=151, Percent_Identity=37.7483443708609, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24647199, Length=141, Percent_Identity=32.6241134751773, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24647193, Length=136, Percent_Identity=33.0882352941176, Blast_Score=66, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 16343; Mature: 16212

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
5.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASLTLLVNDQKRTVDVAPETPLLWVLRDTLGLTGTKFGCGMSLCGACTVLLDGDAVRSC
CCEEEEEECCCCCEEEECCCCCEEEEEHHHHCCCCCCCCCCHHHHHHEEEEECCCHHHHH
QTPVKDAVGHRITTIEGLAAGGSPLQAAWVEEEVPQCGYCQSGQIMSAAALLTRTPDPTD
CCCHHHHHCCEEEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCC
AQIDAAMDGVLCRCGTYQRIRRAIHRAARAKGGAR
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
ASLTLLVNDQKRTVDVAPETPLLWVLRDTLGLTGTKFGCGMSLCGACTVLLDGDAVRSC
CEEEEEECCCCCEEEECCCCCEEEEEHHHHCCCCCCCCCCHHHHHHEEEEECCCHHHHH
QTPVKDAVGHRITTIEGLAAGGSPLQAAWVEEEVPQCGYCQSGQIMSAAALLTRTPDPTD
CCCHHHHHCCEEEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCC
AQIDAAMDGVLCRCGTYQRIRRAIHRAARAKGGAR
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]