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The map label for this gene is iorB [H]

Identifier: 220918393

GI number: 220918393

Start: 3670644

End: 3672767

Strand: Reverse

Name: iorB [H]

Synonym: A2cp1_3297

Alternate gene names: 220918393

Gene position: 3672767-3670644 (Counterclockwise)

Preceding gene: 220918394

Following gene: 220918392

Centisome position: 73.03

GC content: 76.65

Gene sequence:

>2124_bases
ATGAGCGCCGGGGCGCTGGGGCGAAGGGACTTCCTGAAGCTCTCGGCGGGCGCGGGGCTGTGGCTGGCCGTGTCCGGTCC
GGGCCGCGTGCTGGCCGCGGGGCAGGTGGCGGCGGCGGAAGGCTTCAGGCCGTCGGCGTGGCTGCACCTCGCGCCGGACG
GCACCACGACGATCTTCCTCGGCCGCTCGGAGATGGGGCAGGGGACCTACACCGGCATGGCGGTGCTGGTGGCGGAGGAG
CTGGAGGCGGACTGGACCAAGGTGAAGGTCGTCCAGGGCGACGCCGACCCGAAGTACGGCGAGATGGTCACCGGCGGCTC
GCGCTCGGTGCGCAGCGAGTTCATCCCGCTCCGCAAGGCCGGCGCCGCGGCGCGCGAGGTGCTGCTGAAGGCGGGCGCGA
GGCGGCTCGGGGTCCCCGTGCGCGCCTGCCGGGCCGAGGGCGGCGCGGTGGTGCACGCCGCGAGCGGGCGGCGCCTCGGG
TACGGCGAGCTGGCGGCCGACGCGGCGACGCTGCCGGTCCCGGCGAACCCGCGCCTGAAGGATCCGCGGCGGTTCAAGCT
CATCGGCAAGCGCGTGCCGCGCCTCGACACGCCGCCCAAGGTTCGCGGCGAGGCGGTGTTCGGACTCGACGTGCGCGTCT
CGGGCATGCTGCACGCCACGGTGGCGCGGCCGCCGGTGCGCGGCGGGAAGGTGAAGGGCTTCGACGCGGCCGCGGCCGCG
AACGTGCCCGGCGTGCGCAAGGTGGTCGAGGTCCCGAGCGGCATCGCGGTGATCGCCGACTCGACCTGGGCCGCCATCCA
GGGGCGCGAGGCGCTGAAGGCGACCTTCGAGCCGGGCCCGAACGGCGCGCTCGACGGCGCCGCCATCGCGCGCCTGCTCG
CCGAGGCGAAGGTGGACCCGGTCCCGTCGCGCAGCGAGGGCGGGGACGTGGAGCAGGCGCTGGCGGGCGCGGCGCAGCGC
GTGCAGGCCGTGTACGAGCTGCCGCTGCTCGCCCACGCCACCATGGAGCCGATGAACTGCACGGCCCACGTGGCCCTGGG
GAAGGCGGAACTGTGGGCGCCGACCCAGGCGCCGCTCTGGGCCCGCGCCGAGGTGGCGAAGGCGCTCGGCCTCGCCGAGG
CCGCGGTGACGGTGCACGTCACGTTCCTCGGCGGCGGCTTCGGCCGCCGGGCGCTGCCGGACTTCGCGGTCGAGGCGGCG
CACGTGTCGCGGGCGGCGGGCGCGCCGGTCCAGGTCACCTGGACGCGCGAGGACGACCTGCGCCACGACTTCTACCGGCC
GCCGGGGCGCAACGAGCTGCGGGCCGGCCTGGACGCGAAGGGGCGCCTGGTGGCGTGGCACCACGTGGTGCGCAACCCGT
CCATCGGGCAGCAGCTGTTCGGCGAGGCGCGCCGCCGCGGCGACCGGCCGGACACGGTGGAGGGCGCGGCCGACGTGCCG
TACACCGCCCGCGCCGTCCGCGTGGAGCACGCGCTGCCCGAGATCGGCGTGCCGCTCGGCTGGTGGCGCTCGGTGTACTC
GTCGCAGAACGCGTTCGCGGAGGAGGTCTTCGTGGACGAGCTGGCGCGGGCCGCCGGCCAGGACCCGCTCGCGTTCCGCC
TCGCCAACCTCCCGCGCGACAGCCGCCTGCGCGGCGTGCTGCGGCTGGCGGCCGACCGCGCCGGCTGGGGCAAGGCGCCG
CCGGCCGGGCACGCGCTGGGCCTCGCTTGCCACGCGTCGTTCGGCAGCTACGTCGCCCAGGTCGCCGAGGTGTCGGTGCG
AAACGGCCGGATCACCGTGCACCGGGTGGTGTGCGCGGTGGACTGCGGCACCGCCCTCAACCCGGACAGCGTCGAGGCGC
AGGTGGAGGGCTCGGTGGTGTACGGGCTGTCGGCGGCGCTGCGTGGCGAGATCACCGTGAAGGGCGGCGCGGTGGAGCAG
GGCAACTTCGACGCGTACGAGCCGCTCCGGATGAGCGAGATGCCGAGGGTCGAGGTGCACCTCGTCCCGAGCAACGCCGA
GCCCGGCGGCATGGGCGAGCCCGCGCTCCCGCCCATCGCCCCGGCCGTCGCGAACGCGGTGTTCGCCGCCACCGGGGAGC
GGCTGCGCAGGCTGCCGCTCCGGCCGGCGGGGCGCGCAGGGTAG

Upstream 100 bases:

>100_bases
AGATCGACGCCGCCATGGACGGCGTGCTGTGCCGGTGCGGGACGTACCAGCGGATCCGCCGCGCCATCCACCGCGCGGCG
CGGGCCAAGGGAGGTGCGCG

Downstream 100 bases:

>100_bases
CGGGCGACCCCGGCCGCCGCCGGATGCGTTGACGGTCCCGGGCCGGTCGCGCAGAGTGGCGCGGTGCTCCCGTGCCGCGC
CGCGCTCGTCGCCGTCGTCC

Product: molybdopterin binding aldehyde oxidase and xanthine dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 707; Mature: 706

Protein sequence:

>707_residues
MSAGALGRRDFLKLSAGAGLWLAVSGPGRVLAAGQVAAAEGFRPSAWLHLAPDGTTTIFLGRSEMGQGTYTGMAVLVAEE
LEADWTKVKVVQGDADPKYGEMVTGGSRSVRSEFIPLRKAGAAAREVLLKAGARRLGVPVRACRAEGGAVVHAASGRRLG
YGELAADAATLPVPANPRLKDPRRFKLIGKRVPRLDTPPKVRGEAVFGLDVRVSGMLHATVARPPVRGGKVKGFDAAAAA
NVPGVRKVVEVPSGIAVIADSTWAAIQGREALKATFEPGPNGALDGAAIARLLAEAKVDPVPSRSEGGDVEQALAGAAQR
VQAVYELPLLAHATMEPMNCTAHVALGKAELWAPTQAPLWARAEVAKALGLAEAAVTVHVTFLGGGFGRRALPDFAVEAA
HVSRAAGAPVQVTWTREDDLRHDFYRPPGRNELRAGLDAKGRLVAWHHVVRNPSIGQQLFGEARRRGDRPDTVEGAADVP
YTARAVRVEHALPEIGVPLGWWRSVYSSQNAFAEEVFVDELARAAGQDPLAFRLANLPRDSRLRGVLRLAADRAGWGKAP
PAGHALGLACHASFGSYVAQVAEVSVRNGRITVHRVVCAVDCGTALNPDSVEAQVEGSVVYGLSAALRGEITVKGGAVEQ
GNFDAYEPLRMSEMPRVEVHLVPSNAEPGGMGEPALPPIAPAVANAVFAATGERLRRLPLRPAGRAG

Sequences:

>Translated_707_residues
MSAGALGRRDFLKLSAGAGLWLAVSGPGRVLAAGQVAAAEGFRPSAWLHLAPDGTTTIFLGRSEMGQGTYTGMAVLVAEE
LEADWTKVKVVQGDADPKYGEMVTGGSRSVRSEFIPLRKAGAAAREVLLKAGARRLGVPVRACRAEGGAVVHAASGRRLG
YGELAADAATLPVPANPRLKDPRRFKLIGKRVPRLDTPPKVRGEAVFGLDVRVSGMLHATVARPPVRGGKVKGFDAAAAA
NVPGVRKVVEVPSGIAVIADSTWAAIQGREALKATFEPGPNGALDGAAIARLLAEAKVDPVPSRSEGGDVEQALAGAAQR
VQAVYELPLLAHATMEPMNCTAHVALGKAELWAPTQAPLWARAEVAKALGLAEAAVTVHVTFLGGGFGRRALPDFAVEAA
HVSRAAGAPVQVTWTREDDLRHDFYRPPGRNELRAGLDAKGRLVAWHHVVRNPSIGQQLFGEARRRGDRPDTVEGAADVP
YTARAVRVEHALPEIGVPLGWWRSVYSSQNAFAEEVFVDELARAAGQDPLAFRLANLPRDSRLRGVLRLAADRAGWGKAP
PAGHALGLACHASFGSYVAQVAEVSVRNGRITVHRVVCAVDCGTALNPDSVEAQVEGSVVYGLSAALRGEITVKGGAVEQ
GNFDAYEPLRMSEMPRVEVHLVPSNAEPGGMGEPALPPIAPAVANAVFAATGERLRRLPLRPAGRAG
>Mature_706_residues
SAGALGRRDFLKLSAGAGLWLAVSGPGRVLAAGQVAAAEGFRPSAWLHLAPDGTTTIFLGRSEMGQGTYTGMAVLVAEEL
EADWTKVKVVQGDADPKYGEMVTGGSRSVRSEFIPLRKAGAAAREVLLKAGARRLGVPVRACRAEGGAVVHAASGRRLGY
GELAADAATLPVPANPRLKDPRRFKLIGKRVPRLDTPPKVRGEAVFGLDVRVSGMLHATVARPPVRGGKVKGFDAAAAAN
VPGVRKVVEVPSGIAVIADSTWAAIQGREALKATFEPGPNGALDGAAIARLLAEAKVDPVPSRSEGGDVEQALAGAAQRV
QAVYELPLLAHATMEPMNCTAHVALGKAELWAPTQAPLWARAEVAKALGLAEAAVTVHVTFLGGGFGRRALPDFAVEAAH
VSRAAGAPVQVTWTREDDLRHDFYRPPGRNELRAGLDAKGRLVAWHHVVRNPSIGQQLFGEARRRGDRPDTVEGAADVPY
TARAVRVEHALPEIGVPLGWWRSVYSSQNAFAEEVFVDELARAAGQDPLAFRLANLPRDSRLRGVLRLAADRAGWGKAPP
AGHALGLACHASFGSYVAQVAEVSVRNGRITVHRVVCAVDCGTALNPDSVEAQVEGSVVYGLSAALRGEITVKGGAVEQG
NFDAYEPLRMSEMPRVEVHLVPSNAEPGGMGEPALPPIAPAVANAVFAATGERLRRLPLRPAGRAG

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786478, Length=426, Percent_Identity=24.8826291079812, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1789230, Length=392, Percent_Identity=23.9795918367347, Blast_Score=66, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012368
- InterPro:   IPR006311 [H]

Pfam domain/function: PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 74216; Mature: 74084

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAGALGRRDFLKLSAGAGLWLAVSGPGRVLAAGQVAAAEGFRPSAWLHLAPDGTTTIFL
CCCCCCCCCHHEEEECCCCEEEEECCCCCEEECCCCHHCCCCCCCCEEEECCCCCEEEEE
GRSEMGQGTYTGMAVLVAEELEADWTKVKVVQGDADPKYGEMVTGGSRSVRSEFIPLRKA
ECCCCCCCCHHCEEEEEEHHHCCCCEEEEEEECCCCCCCCCEECCCCHHHHHHHCCHHHH
GAAAREVLLKAGARRLGVPVRACRAEGGAVVHAASGRRLGYGELAADAATLPVPANPRLK
HHHHHHHHHHHCHHHCCCCHHHHCCCCCEEEEECCCCCCCCCHHHCCCEECCCCCCCCCC
DPRRFKLIGKRVPRLDTPPKVRGEAVFGLDVRVSGMLHATVARPPVRGGKVKGFDAAAAA
CCHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEECCEEEEEECCCCCCCCEECCCCCHHHC
NVPGVRKVVEVPSGIAVIADSTWAAIQGREALKATFEPGPNGALDGAAIARLLAEAKVDP
CCCCHHHHHHCCCCEEEEECCCCHHHCCCHHHHEECCCCCCCCCCHHHHHHHHHHHCCCC
VPSRSEGGDVEQALAGAAQRVQAVYELPLLAHATMEPMNCTAHVALGKAELWAPTQAPLW
CCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCEEEEEECCHHCCCCCCCCCH
ARAEVAKALGLAEAAVTVHVTFLGGGFGRRALPDFAVEAAHVSRAAGAPVQVTWTREDDL
HHHHHHHHHHHHEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCC
RHDFYRPPGRNELRAGLDAKGRLVAWHHVVRNPSIGQQLFGEARRRGDRPDTVEGAADVP
HHHHCCCCCCCHHHCCCCCCCCEEEEEHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCC
YTARAVRVEHALPEIGVPLGWWRSVYSSQNAFAEEVFVDELARAAGQDPLAFRLANLPRD
CCHHEEEHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEHHHCCCCH
SRLRGVLRLAADRAGWGKAPPAGHALGLACHASFGSYVAQVAEVSVRNGRITVHRVVCAV
HHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCEEEEEEEEEEE
DCGTALNPDSVEAQVEGSVVYGLSAALRGEITVKGGAVEQGNFDAYEPLRMSEMPRVEVH
ECCCCCCCCCCEEEECCEEEEEEHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEE
LVPSNAEPGGMGEPALPPIAPAVANAVFAATGERLRRLPLRPAGRAG
EEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SAGALGRRDFLKLSAGAGLWLAVSGPGRVLAAGQVAAAEGFRPSAWLHLAPDGTTTIFL
CCCCCCCCHHEEEECCCCEEEEECCCCCEEECCCCHHCCCCCCCCEEEECCCCCEEEEE
GRSEMGQGTYTGMAVLVAEELEADWTKVKVVQGDADPKYGEMVTGGSRSVRSEFIPLRKA
ECCCCCCCCHHCEEEEEEHHHCCCCEEEEEEECCCCCCCCCEECCCCHHHHHHHCCHHHH
GAAAREVLLKAGARRLGVPVRACRAEGGAVVHAASGRRLGYGELAADAATLPVPANPRLK
HHHHHHHHHHHCHHHCCCCHHHHCCCCCEEEEECCCCCCCCCHHHCCCEECCCCCCCCCC
DPRRFKLIGKRVPRLDTPPKVRGEAVFGLDVRVSGMLHATVARPPVRGGKVKGFDAAAAA
CCHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEECCEEEEEECCCCCCCCEECCCCCHHHC
NVPGVRKVVEVPSGIAVIADSTWAAIQGREALKATFEPGPNGALDGAAIARLLAEAKVDP
CCCCHHHHHHCCCCEEEEECCCCHHHCCCHHHHEECCCCCCCCCCHHHHHHHHHHHCCCC
VPSRSEGGDVEQALAGAAQRVQAVYELPLLAHATMEPMNCTAHVALGKAELWAPTQAPLW
CCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCEEEEEECCHHCCCCCCCCCH
ARAEVAKALGLAEAAVTVHVTFLGGGFGRRALPDFAVEAAHVSRAAGAPVQVTWTREDDL
HHHHHHHHHHHHEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCC
RHDFYRPPGRNELRAGLDAKGRLVAWHHVVRNPSIGQQLFGEARRRGDRPDTVEGAADVP
HHHHCCCCCCCHHHCCCCCCCCEEEEEHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCC
YTARAVRVEHALPEIGVPLGWWRSVYSSQNAFAEEVFVDELARAAGQDPLAFRLANLPRD
CCHHEEEHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEHHHCCCCH
SRLRGVLRLAADRAGWGKAPPAGHALGLACHASFGSYVAQVAEVSVRNGRITVHRVVCAV
HHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCEEEEEEEEEEE
DCGTALNPDSVEAQVEGSVVYGLSAALRGEITVKGGAVEQGNFDAYEPLRMSEMPRVEVH
ECCCCCCCCCCEEEECCEEEEEEHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEE
LVPSNAEPGGMGEPALPPIAPAVANAVFAATGERLRRLPLRPAGRAG
EEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]