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The map label for this gene is hscA [H]

Identifier: 220918327

GI number: 220918327

Start: 3588234

End: 3591023

Strand: Reverse

Name: hscA [H]

Synonym: A2cp1_3231

Alternate gene names: 220918327

Gene position: 3591023-3588234 (Counterclockwise)

Preceding gene: 220918328

Following gene: 220918326

Centisome position: 71.4

GC content: 80.11

Gene sequence:

>2790_bases
ATGTCCGGCCCGCGCTACGTCGTCGGCATCGACCTCGGCACGGTCAACTCCGCGCTCGCCTCGGTGGACCTCGCGCGCGC
GGGCGACCTCGCCGAGGCGGTCGAGGCGCTGCCGGTCCCGCAGCTGGTCCGGCCGGGCGAGGTGGAGCCGCGGCGCCTGC
TGCCGTCCTCGGCCTACCTGCCCGGCCCGGAGCTGCCGCCGGCCGCCACCCGGCTGCCCTGGGGCGAGCGCGCCATCGTG
GTCGGCGAGCTGGCGCGCGAGCAGGGCGCCCGCGTGCCCGGCCGGTTGGTGGCCTCGGCGAAGAGCTGGCTCGCGAACCC
CCGGGCCGACCGGACCGCGCCGATCCTTCCCTGGGGGGCGCCCGAGGGCGTGCCGCGCATCTCGCCGGTGGCCGCCTCGG
CGCTGGTCCTGGGCCACCTCCGCGATGCCTGGGAGGCCGCCCACCCCGGCGCACCGCTCGTCGAGCAGGAGCTGACGCTG
GCGGTGCCCGCGTCGTTCGACGCCGCCGCGCGCGAGCTGACCCTCGCGGCGGCGCGCCAAGCGGGGCTGCCGCGCGCGGC
GCTGGTCGAGGAGCCGCAGGCCGCGTTCCACGACTGGGCCTCGCGCCACCGCGCCGACCTGGGCGCCGCGCTGGGCCTCC
CCGGCGGCGAGGGCGCCGCGCAGGTGCTGGTGGTCGACGTGGGCGGCGGCACCACCGACCTCACGCTGGTCCGCGCCGAG
GTGCACGACGGGCGGCCGTCGCTCACCCGCCTCGCCGTCGGCGATCACCTGCTGCTCGGCGGCGACAACGTGGACCTGGC
GCTGGCGCGGGCGGTGGAGGGGAGGCTGGGCGGACGGCTCGACCCGGCGCGCTTCGGCGCGCTGGTGCAGGCGTGCCGGC
TCGCGAAGGAGCGGCTGCTGGCCGCGGGCGGCCCGGAGCGCGTCCCGGTGGCCGTGGCCGGCGCGGGGAGCCGCATCGTC
GCCGGCGCGGTCTCGGCGGAGCTGACGCGCGACGAGGTGCGCGCGCTGGTGCTGGACGGCTTCTTCCCTCGGGTCGGTCC
GGAGGACCGCCCCCGCCGCGCGCCGCGCACCGCCGGGCTGGCGGAGCTGGGGTTGCCCTACGAGCCGGACCCGGCGGTCA
CCCGCCACGTGGCCGCGTTCCTCGCGCTGCACGCGGCCGAGGCGGGCGCCGTGGGGGGCGGGCCGGCCCGGCCGGACGCG
GTGCTCCTCAACGGCGGCACCTTCGCCGCGCCGGAGGTGCGTGCGCGCCTCGCCGAGGCCGTGTCCGCGCTGTTCCCGGG
CGCGCCGCCGGTGCGCGCGCTCGCCAGCCCCGCGCTCGACCTCGCGGTGGCGCGCGGCGCGGCGCTCTCGGCGCTGGCCC
GGCGCGGCGTGGGCCTGCGCATCGGCGGCGGCACCCCGCGGGCGTTCTACGTGGGCATCGCCGCGCCGGAGGGCGAGCGG
GCGCTCTGCGTGGTGCCGCGCCACGCCGAGGAGGGGACGCGGGTCGCGGTGCCGCGAACGTTCCGGCTGGCGCTGGGGCG
GCCGGTCCGCTTCGCGCTGCTCGCGTCGTCCGCGCCGCGGCTGGAGGGGCCGGGCGACGTCGTCGAGCCGGGCGACGACC
TGGTCCCGCTGCCGCCGGTGGAGACGGTGCTCTCGGCACCGGGGCAGGGCGACGCCGAGGTGCCGGTGCGCCTCGAGGCG
GTGCTCACCGAGATCGGGACGCTCGAGCTGTGGTGCGCCGCCACCGATCGCGACGCGCGCTGGCGGCTCGAGTTCTCGCT
GCGGGCGGGCGCCGCCGACGCAGGGGCGCCGGGACGTCCCGCGGAGACGGCGGCGGTGCCGCGCGGGCTGGAGGAGGCGC
ACGCGCTGGTGGACCTGTTCTACGGCAGGAAGGGGGCGGTCGAGCGCAAGGAGGTGAAGGGGCTGTTCCGGGCGCTCGAG
AAGGTCCTCGGGCCGCGCGACGCCTGGTCCACGCCGGTGGTGCGGGACCTGTGGGCGGCGCTGCACGCGGGCCGGGGGCG
GCGGCGGCGCACCGCCGACCACGAGCGCACCTGGCTCCAGCTCACCGGCTTCTGCCTGCGCCCCGGCTTCGGCGCCCCGC
TCGACGCCTGGCGGGCCGGGGAGACCTGGAAGGCGTTCGGCGAGGGGCTGCAGTACCAGGGCGACGCGCGCGCCTGGGCG
GCCTGGTGGGTCACCTGGCGGCGCATCGCCGGCGGGCTCGAGGCCGCCGCGCAGCGGCGGCTGCTCGAGACGGTGCGGCC
GTTCCTCCAGCCGCGCGATCCGCGCCGCCCGCCGCCGAAGGTGGCCGGGGTCCGGCCGATGGCGGAGGACGAGATGGTCC
GGCTCGCCGGGAGCCTCGAGCGGATCGACGCGGCCGAGAAGGAGGAGCTCGGCGGGTGGCTGCTCGCGCGCGCCGAGGCG
GAGGGCCCTGCGGCGCACCTGCTCTGGGCGATCGGCCGCCTGGGCGCGCGCGTCCCGTTCCACGCCAGCGTGCACCAGGT
GGTCCCGCCCGCGGTCGCGGAGGCCTGGATCGACCGGCTGCTCGCGGCCGCGCCGCCGCGGGAGGTGGCGTTCGCGCTGG
GGCAGCTCGCCCGCCGGAGCGGCGATCGGGTCCGCGACGTGGGCGAGGCCGCGCGCGCGCGGGCGCTGGCCGCGCTCGCG
GCCGCCGGCGTCCCGGAGGAGCAGGCACGGCCGGTGCGCGAGGTGGTCGAGGCGAGCGCGGAGGCCGAGCAGCGGATCTT
CGGCGAGAGCCTCCCGGCCGGGCTCCGGCTGGTCGCGGGGGAGGAGGACCCCGCCGCCCCGCCCACGTGA

Upstream 100 bases:

>100_bases
GTCCGGACGAGCGCTGGTCGCTGGAGTGGACCCTGCGCCAGCCGCCTGGCGCCGGCGGCGAGCCGGAGCCGGCGGCCCCG
CCCGCCTGATCCGGAGCCAC

Downstream 100 bases:

>100_bases
CGAGCAGTGAAGCGCGCCCGCCGGGGCGAACGGCGCGCCGTCGCGCCGGCCGGCGGGGTAGGATGCGCCCCATGGTTCGC
CTCAGCTGGCCGCTCGCGCT

Product: DnaK-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 929; Mature: 928

Protein sequence:

>929_residues
MSGPRYVVGIDLGTVNSALASVDLARAGDLAEAVEALPVPQLVRPGEVEPRRLLPSSAYLPGPELPPAATRLPWGERAIV
VGELAREQGARVPGRLVASAKSWLANPRADRTAPILPWGAPEGVPRISPVAASALVLGHLRDAWEAAHPGAPLVEQELTL
AVPASFDAAARELTLAAARQAGLPRAALVEEPQAAFHDWASRHRADLGAALGLPGGEGAAQVLVVDVGGGTTDLTLVRAE
VHDGRPSLTRLAVGDHLLLGGDNVDLALARAVEGRLGGRLDPARFGALVQACRLAKERLLAAGGPERVPVAVAGAGSRIV
AGAVSAELTRDEVRALVLDGFFPRVGPEDRPRRAPRTAGLAELGLPYEPDPAVTRHVAAFLALHAAEAGAVGGGPARPDA
VLLNGGTFAAPEVRARLAEAVSALFPGAPPVRALASPALDLAVARGAALSALARRGVGLRIGGGTPRAFYVGIAAPEGER
ALCVVPRHAEEGTRVAVPRTFRLALGRPVRFALLASSAPRLEGPGDVVEPGDDLVPLPPVETVLSAPGQGDAEVPVRLEA
VLTEIGTLELWCAATDRDARWRLEFSLRAGAADAGAPGRPAETAAVPRGLEEAHALVDLFYGRKGAVERKEVKGLFRALE
KVLGPRDAWSTPVVRDLWAALHAGRGRRRRTADHERTWLQLTGFCLRPGFGAPLDAWRAGETWKAFGEGLQYQGDARAWA
AWWVTWRRIAGGLEAAAQRRLLETVRPFLQPRDPRRPPPKVAGVRPMAEDEMVRLAGSLERIDAAEKEELGGWLLARAEA
EGPAAHLLWAIGRLGARVPFHASVHQVVPPAVAEAWIDRLLAAAPPREVAFALGQLARRSGDRVRDVGEAARARALAALA
AAGVPEEQARPVREVVEASAEAEQRIFGESLPAGLRLVAGEEDPAAPPT

Sequences:

>Translated_929_residues
MSGPRYVVGIDLGTVNSALASVDLARAGDLAEAVEALPVPQLVRPGEVEPRRLLPSSAYLPGPELPPAATRLPWGERAIV
VGELAREQGARVPGRLVASAKSWLANPRADRTAPILPWGAPEGVPRISPVAASALVLGHLRDAWEAAHPGAPLVEQELTL
AVPASFDAAARELTLAAARQAGLPRAALVEEPQAAFHDWASRHRADLGAALGLPGGEGAAQVLVVDVGGGTTDLTLVRAE
VHDGRPSLTRLAVGDHLLLGGDNVDLALARAVEGRLGGRLDPARFGALVQACRLAKERLLAAGGPERVPVAVAGAGSRIV
AGAVSAELTRDEVRALVLDGFFPRVGPEDRPRRAPRTAGLAELGLPYEPDPAVTRHVAAFLALHAAEAGAVGGGPARPDA
VLLNGGTFAAPEVRARLAEAVSALFPGAPPVRALASPALDLAVARGAALSALARRGVGLRIGGGTPRAFYVGIAAPEGER
ALCVVPRHAEEGTRVAVPRTFRLALGRPVRFALLASSAPRLEGPGDVVEPGDDLVPLPPVETVLSAPGQGDAEVPVRLEA
VLTEIGTLELWCAATDRDARWRLEFSLRAGAADAGAPGRPAETAAVPRGLEEAHALVDLFYGRKGAVERKEVKGLFRALE
KVLGPRDAWSTPVVRDLWAALHAGRGRRRRTADHERTWLQLTGFCLRPGFGAPLDAWRAGETWKAFGEGLQYQGDARAWA
AWWVTWRRIAGGLEAAAQRRLLETVRPFLQPRDPRRPPPKVAGVRPMAEDEMVRLAGSLERIDAAEKEELGGWLLARAEA
EGPAAHLLWAIGRLGARVPFHASVHQVVPPAVAEAWIDRLLAAAPPREVAFALGQLARRSGDRVRDVGEAARARALAALA
AAGVPEEQARPVREVVEASAEAEQRIFGESLPAGLRLVAGEEDPAAPPT
>Mature_928_residues
SGPRYVVGIDLGTVNSALASVDLARAGDLAEAVEALPVPQLVRPGEVEPRRLLPSSAYLPGPELPPAATRLPWGERAIVV
GELAREQGARVPGRLVASAKSWLANPRADRTAPILPWGAPEGVPRISPVAASALVLGHLRDAWEAAHPGAPLVEQELTLA
VPASFDAAARELTLAAARQAGLPRAALVEEPQAAFHDWASRHRADLGAALGLPGGEGAAQVLVVDVGGGTTDLTLVRAEV
HDGRPSLTRLAVGDHLLLGGDNVDLALARAVEGRLGGRLDPARFGALVQACRLAKERLLAAGGPERVPVAVAGAGSRIVA
GAVSAELTRDEVRALVLDGFFPRVGPEDRPRRAPRTAGLAELGLPYEPDPAVTRHVAAFLALHAAEAGAVGGGPARPDAV
LLNGGTFAAPEVRARLAEAVSALFPGAPPVRALASPALDLAVARGAALSALARRGVGLRIGGGTPRAFYVGIAAPEGERA
LCVVPRHAEEGTRVAVPRTFRLALGRPVRFALLASSAPRLEGPGDVVEPGDDLVPLPPVETVLSAPGQGDAEVPVRLEAV
LTEIGTLELWCAATDRDARWRLEFSLRAGAADAGAPGRPAETAAVPRGLEEAHALVDLFYGRKGAVERKEVKGLFRALEK
VLGPRDAWSTPVVRDLWAALHAGRGRRRRTADHERTWLQLTGFCLRPGFGAPLDAWRAGETWKAFGEGLQYQGDARAWAA
WWVTWRRIAGGLEAAAQRRLLETVRPFLQPRDPRRPPPKVAGVRPMAEDEMVRLAGSLERIDAAEKEELGGWLLARAEAE
GPAAHLLWAIGRLGARVPFHASVHQVVPPAVAEAWIDRLLAAAPPREVAFALGQLARRSGDRVRDVGEAARARALAALAA
AGVPEEQARPVREVVEASAEAEQRIFGESLPAGLRLVAGEEDPAAPPT

Specific function: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by hscB [H]

COG id: COG0443

COG function: function code O; Molecular chaperone

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 70 family [H]

Homologues:

Organism=Escherichia coli, GI1788875, Length=324, Percent_Identity=30.2469135802469, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1786196, Length=469, Percent_Identity=25.5863539445629, Blast_Score=70, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018181
- InterPro:   IPR001023
- InterPro:   IPR013126
- InterPro:   IPR010236 [H]

Pfam domain/function: PF00012 HSP70 [H]

EC number: NA

Molecular weight: Translated: 97590; Mature: 97459

Theoretical pI: Translated: 7.49; Mature: 7.49

Prosite motif: PS00436 PEROXIDASE_2 ; PS00329 HSP70_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGPRYVVGIDLGTVNSALASVDLARAGDLAEAVEALPVPQLVRPGEVEPRRLLPSSAYL
CCCCCEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHCCCCHHCCCCCCCHHHCCCCCCCC
PGPELPPAATRLPWGERAIVVGELAREQGARVPGRLVASAKSWLANPRADRTAPILPWGA
CCCCCCCCCCCCCCCCCEEEHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCC
PEGVPRISPVAASALVLGHLRDAWEAAHPGAPLVEQELTLAVPASFDAAARELTLAAARQ
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHCCEEEEECCCCHHHHHHHHHHHHHH
AGLPRAALVEEPQAAFHDWASRHRADLGAALGLPGGEGAAQVLVVDVGGGTTDLTLVRAE
CCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCEEEEEEEE
VHDGRPSLTRLAVGDHLLLGGDNVDLALARAVEGRLGGRLDPARFGALVQACRLAKERLL
CCCCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
AAGGPERVPVAVAGAGSRIVAGAVSAELTRDEVRALVLDGFFPRVGPEDRPRRAPRTAGL
HCCCCCCCCEEEECCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCH
AELGLPYEPDPAVTRHVAAFLALHAAEAGAVGGGPARPDAVLLNGGTFAAPEVRARLAEA
HHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHH
VSALFPGAPPVRALASPALDLAVARGAALSALARRGVGLRIGGGTPRAFYVGIAAPEGER
HHHHCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEEEECCCCCC
ALCVVPRHAEEGTRVAVPRTFRLALGRPVRFALLASSAPRLEGPGDVVEPGDDLVPLPPV
EEEEECCCCCCCCEEECCCHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCH
ETVLSAPGQGDAEVPVRLEAVLTEIGTLELWCAATDRDARWRLEFSLRAGAADAGAPGRP
HHHHCCCCCCCCCCCCHHHHHHHHCCCEEEEEEECCCCCEEEEEEEEECCCCCCCCCCCC
AETAAVPRGLEEAHALVDLFYGRKGAVERKEVKGLFRALEKVLGPRDAWSTPVVRDLWAA
CHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
LHAGRGRRRRTADHERTWLQLTGFCLRPGFGAPLDAWRAGETWKAFGEGLQYQGDARAWA
HHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHCCCCCCCCCHHHH
AWWVTWRRIAGGLEAAAQRRLLETVRPFLQPRDPRRPPPKVAGVRPMAEDEMVRLAGSLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
RIDAAEKEELGGWLLARAEAEGPAAHLLWAIGRLGARVPFHASVHQVVPPAVAEAWIDRL
HHCCHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCHHHHCCHHHHHHHHHHH
LAAAPPREVAFALGQLARRSGDRVRDVGEAARARALAALAAAGVPEEQARPVREVVEASA
HHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
EAEQRIFGESLPAGLRLVAGEEDPAAPPT
HHHHHHHHCCCCCCEEEEECCCCCCCCCC
>Mature Secondary Structure 
SGPRYVVGIDLGTVNSALASVDLARAGDLAEAVEALPVPQLVRPGEVEPRRLLPSSAYL
CCCCEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHCCCCHHCCCCCCCHHHCCCCCCCC
PGPELPPAATRLPWGERAIVVGELAREQGARVPGRLVASAKSWLANPRADRTAPILPWGA
CCCCCCCCCCCCCCCCCEEEHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCC
PEGVPRISPVAASALVLGHLRDAWEAAHPGAPLVEQELTLAVPASFDAAARELTLAAARQ
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHCCEEEEECCCCHHHHHHHHHHHHHH
AGLPRAALVEEPQAAFHDWASRHRADLGAALGLPGGEGAAQVLVVDVGGGTTDLTLVRAE
CCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCEEEEEEEE
VHDGRPSLTRLAVGDHLLLGGDNVDLALARAVEGRLGGRLDPARFGALVQACRLAKERLL
CCCCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
AAGGPERVPVAVAGAGSRIVAGAVSAELTRDEVRALVLDGFFPRVGPEDRPRRAPRTAGL
HCCCCCCCCEEEECCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCH
AELGLPYEPDPAVTRHVAAFLALHAAEAGAVGGGPARPDAVLLNGGTFAAPEVRARLAEA
HHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHH
VSALFPGAPPVRALASPALDLAVARGAALSALARRGVGLRIGGGTPRAFYVGIAAPEGER
HHHHCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEEEECCCCCC
ALCVVPRHAEEGTRVAVPRTFRLALGRPVRFALLASSAPRLEGPGDVVEPGDDLVPLPPV
EEEEECCCCCCCCEEECCCHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCH
ETVLSAPGQGDAEVPVRLEAVLTEIGTLELWCAATDRDARWRLEFSLRAGAADAGAPGRP
HHHHCCCCCCCCCCCCHHHHHHHHCCCEEEEEEECCCCCEEEEEEEEECCCCCCCCCCCC
AETAAVPRGLEEAHALVDLFYGRKGAVERKEVKGLFRALEKVLGPRDAWSTPVVRDLWAA
CHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
LHAGRGRRRRTADHERTWLQLTGFCLRPGFGAPLDAWRAGETWKAFGEGLQYQGDARAWA
HHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHCCCCCCCCCHHHH
AWWVTWRRIAGGLEAAAQRRLLETVRPFLQPRDPRRPPPKVAGVRPMAEDEMVRLAGSLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
RIDAAEKEELGGWLLARAEAEGPAAHLLWAIGRLGARVPFHASVHQVVPPAVAEAWIDRL
HHCCHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCHHHHCCHHHHHHHHHHH
LAAAPPREVAFALGQLARRSGDRVRDVGEAARARALAALAAAGVPEEQARPVREVVEASA
HHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
EAEQRIFGESLPAGLRLVAGEEDPAAPPT
HHHHHHHHCCCCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA