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The map label for this gene is macB [H]

Identifier: 220918263

GI number: 220918263

Start: 3506331

End: 3507560

Strand: Reverse

Name: macB [H]

Synonym: A2cp1_3166

Alternate gene names: 220918263

Gene position: 3507560-3506331 (Counterclockwise)

Preceding gene: 220918264

Following gene: 220918262

Centisome position: 69.74

GC content: 72.44

Gene sequence:

>1230_bases
GTGAACCTGCTCCAGACCCTGCGCGTGGCGCTGCGCGCGCTGCGCCGCTCCAAGATGCGCTCGTTCCTCACCGCGCTCGG
GATCGTCATCGGCGTGGCCGCGGTGATCGCCATGGTGGCGCTGGGCGACGGGGCCCGCGCGCAGGTGGCGAAGACGTTCG
AGTCGATGGGCTCGAACCTCCTCATGGTGCTGCCCGGCAGCACCACCGCCGGCGGCGCCCGCGGCGGGTTCGGGAGCCTG
CCCACGCTGACCTGGGACGACCTGCGCGCCATCCAGAACGAGGTCCCCTCGGTGCGCTACGCCGCGCCGCAGCTCCGCAC
CACCGCCTCGATCCAGTCGGAGGACCTGAACTGGACCACCTCGGTGACCGGCACCGGCGCCGAGTTCTTCGCCATCCGGA
ACTGGCCGGTGGCGCAGGGTGCGCTGTTCGGGCCCTCGGACGTCGACTCCGGCACCAAGGTGATCGTGCTCGGGAAGACG
GTCGCCGACGAGCTGTTCGGCGCGGGCGCGAGCCCGGTCGGCCAGCAGGTCCGCGTGAAGAACGTGCCGTTCCAGGTGGT
GGGCGTGCTCGCCGCCAAGGGCCAGTCGCCCATGGGCCAGGACCTCGACGACGCGGTGTTCGTGCCCTACTCGACGTACC
TCGCGAAGGTGCAGGGCGGCCTGAAGAACCTCATCCCCGGGGTCATCGCGGTGAGCGCGCTGGACTCCGCCTCGACCGCG
CGCGCCGAGCAGCAGGTGCGCGCGCTGCTCCGCGACCGCCACCGGCTGGCCGACGGGGCGGACGACGACTTCTCGATCCG
CAACCTGGCCGAGTTCGCGAGCGCGCAGAAGGAGGGCACCGCCACGCTCACCACGCTGCTGCTCGCCATCGCGGCGGTGT
CCCTCGGCGTGGGCGGCATCGGCATCATGAACATCATGCTGGTGTCGGTGACCGAGCGCACCCGCGAGATCGGCGTCCGC
ATGGCGGTGGGCGCGCGCGCGCGCGACGTCCTCCTGCAGTTCCTCGCCGAGGCGCTGGTCCTCTCGCTCGCCGGCGGCGT
GGTGGGGGTGGCGCTGGGCCTCGGGATCTCCTTCTGGATGGCCCGGGCCTTCGGCTGGCCGGTCATGTTCCGCGCCGACG
TGGTGCTGATCGCGGTCGGCTTCAGCGGGCTGGTGGGCGTCGCGTTCGGGCTCTACCCGGCCCGCCGCGCCTCCCGGCTC
GATCCCATCCAGGCGCTGAGGTTCGAATGA

Upstream 100 bases:

>100_bases
ACGGCAAGCTCCGCTCCGACACGCGGCAGGCGCCGGTGGCGGCGGTGCCGCCGCCCGCCGACGAGGCCGGCGGCGCGGAC
GGGCGGGAAGGAGGCGCGGC

Downstream 100 bases:

>100_bases
CGAACGCCCCGCGGCTCGCTGCCCTCCTCCTGTTCGCCCCGGCGCTGGCGCTAGGGCAGGCCGCCCCGCCGCCGGCCGCT
GCGCCGCCTCCGGACGCGCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MNLLQTLRVALRALRRSKMRSFLTALGIVIGVAAVIAMVALGDGARAQVAKTFESMGSNLLMVLPGSTTAGGARGGFGSL
PTLTWDDLRAIQNEVPSVRYAAPQLRTTASIQSEDLNWTTSVTGTGAEFFAIRNWPVAQGALFGPSDVDSGTKVIVLGKT
VADELFGAGASPVGQQVRVKNVPFQVVGVLAAKGQSPMGQDLDDAVFVPYSTYLAKVQGGLKNLIPGVIAVSALDSASTA
RAEQQVRALLRDRHRLADGADDDFSIRNLAEFASAQKEGTATLTTLLLAIAAVSLGVGGIGIMNIMLVSVTERTREIGVR
MAVGARARDVLLQFLAEALVLSLAGGVVGVALGLGISFWMARAFGWPVMFRADVVLIAVGFSGLVGVAFGLYPARRASRL
DPIQALRFE

Sequences:

>Translated_409_residues
MNLLQTLRVALRALRRSKMRSFLTALGIVIGVAAVIAMVALGDGARAQVAKTFESMGSNLLMVLPGSTTAGGARGGFGSL
PTLTWDDLRAIQNEVPSVRYAAPQLRTTASIQSEDLNWTTSVTGTGAEFFAIRNWPVAQGALFGPSDVDSGTKVIVLGKT
VADELFGAGASPVGQQVRVKNVPFQVVGVLAAKGQSPMGQDLDDAVFVPYSTYLAKVQGGLKNLIPGVIAVSALDSASTA
RAEQQVRALLRDRHRLADGADDDFSIRNLAEFASAQKEGTATLTTLLLAIAAVSLGVGGIGIMNIMLVSVTERTREIGVR
MAVGARARDVLLQFLAEALVLSLAGGVVGVALGLGISFWMARAFGWPVMFRADVVLIAVGFSGLVGVAFGLYPARRASRL
DPIQALRFE
>Mature_409_residues
MNLLQTLRVALRALRRSKMRSFLTALGIVIGVAAVIAMVALGDGARAQVAKTFESMGSNLLMVLPGSTTAGGARGGFGSL
PTLTWDDLRAIQNEVPSVRYAAPQLRTTASIQSEDLNWTTSVTGTGAEFFAIRNWPVAQGALFGPSDVDSGTKVIVLGKT
VADELFGAGASPVGQQVRVKNVPFQVVGVLAAKGQSPMGQDLDDAVFVPYSTYLAKVQGGLKNLIPGVIAVSALDSASTA
RAEQQVRALLRDRHRLADGADDDFSIRNLAEFASAQKEGTATLTTLLLAIAAVSLGVGGIGIMNIMLVSVTERTREIGVR
MAVGARARDVLLQFLAEALVLSLAGGVVGVALGLGISFWMARAFGWPVMFRADVVLIAVGFSGLVGVAFGLYPARRASRL
DPIQALRFE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=411, Percent_Identity=38.1995133819951, Blast_Score=223, Evalue=1e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 42896; Mature: 42896

Theoretical pI: Translated: 10.48; Mature: 10.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLLQTLRVALRALRRSKMRSFLTALGIVIGVAAVIAMVALGDGARAQVAKTFESMGSNL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCE
LMVLPGSTTAGGARGGFGSLPTLTWDDLRAIQNEVPSVRYAAPQLRTTASIQSEDLNWTT
EEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCCHHHHHHCCCCCCCCEEE
SVTGTGAEFFAIRNWPVAQGALFGPSDVDSGTKVIVLGKTVADELFGAGASPVGQQVRVK
EECCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHCCCCCCCCCCEEEC
NVPFQVVGVLAAKGQSPMGQDLDDAVFVPYSTYLAKVQGGLKNLIPGVIAVSALDSASTA
CCCHHHHHHHHHCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
RAEQQVRALLRDRHRLADGADDDFSIRNLAEFASAQKEGTATLTTLLLAIAAVSLGVGGI
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHH
GIMNIMLVSVTERTREIGVRMAVGARARDVLLQFLAEALVLSLAGGVVGVALGLGISFWM
HHHHHHHHHHHHHHHHHCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARAFGWPVMFRADVVLIAVGFSGLVGVAFGLYPARRASRLDPIQALRFE
HHHHCCCCEECCCEEEEEECHHHHHHHHHHHCHHHHHCCCCHHHHHCCC
>Mature Secondary Structure
MNLLQTLRVALRALRRSKMRSFLTALGIVIGVAAVIAMVALGDGARAQVAKTFESMGSNL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCE
LMVLPGSTTAGGARGGFGSLPTLTWDDLRAIQNEVPSVRYAAPQLRTTASIQSEDLNWTT
EEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCCHHHHHHCCCCCCCCEEE
SVTGTGAEFFAIRNWPVAQGALFGPSDVDSGTKVIVLGKTVADELFGAGASPVGQQVRVK
EECCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHCCCCCCCCCCEEEC
NVPFQVVGVLAAKGQSPMGQDLDDAVFVPYSTYLAKVQGGLKNLIPGVIAVSALDSASTA
CCCHHHHHHHHHCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
RAEQQVRALLRDRHRLADGADDDFSIRNLAEFASAQKEGTATLTTLLLAIAAVSLGVGGI
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHH
GIMNIMLVSVTERTREIGVRMAVGARARDVLLQFLAEALVLSLAGGVVGVALGLGISFWM
HHHHHHHHHHHHHHHHHCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARAFGWPVMFRADVVLIAVGFSGLVGVAFGLYPARRASRLDPIQALRFE
HHHHCCCCEECCCEEEEEECHHHHHHHHHHHCHHHHHCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA