| Definition | Anaeromyxobacter dehalogenans 2CP-1 chromosome, complete genome. |
|---|---|
| Accession | NC_011891 |
| Length | 5,029,329 |
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The map label for this gene is yngF [H]
Identifier: 220917401
GI number: 220917401
Start: 2551426
End: 2552199
Strand: Reverse
Name: yngF [H]
Synonym: A2cp1_2301
Alternate gene names: 220917401
Gene position: 2552199-2551426 (Counterclockwise)
Preceding gene: 220917402
Following gene: 220917400
Centisome position: 50.75
GC content: 77.13
Gene sequence:
>774_bases ATGGATCTCCGGGTGGAGCGCAGAGACGCGGTCGAGGTCTGGACGATCGACGGCGCCTCGCGCCGGAACTCGATCACCGT GGGGCTGCTCGGCGCGCTGCGCGCGCAGCTGGCGCGCGCCGGGGGCGACCGGGCCCTGCGCTGCGTGGTGATCACCGGCG ACGGCGACAAGGCGTTCTGCGCCGGCGCCGATCTGAAGGAGCGCGCCGGGATGTCCGCCGACGACGTGCACCGGTTCCAC GAGGGCCTGCGCGACGCCCTCCGCGGCATCGAGCAGGCGCCGCAGCCGTTCGTGGCCGCGCTGAACGGCGCGGCGCTGGG CGGCGGCCTGGAGCTGGCGCTCGCCTGCGACCTGCGCGTCGCCGCCGACTCGGCGCAGCTCGGGCTGCCGGAGGTCGCGC TCGGCATCATCCCGGGCGGCGGCGGCACGCAGCGGCTGGCGCGGCTGGTGGGCGTGGCGCGCGCGAAGGACCTCGTCCTC ACCGCGCGCCGGATCGGCGCCGCCGAGGCGCTCGCCATGGGGCTCGTCACGCAGATCGCGCCGCCGGGGCGGCTGCTCGA CGACGCGCTCGCGCTGGCCGGGCGCATCGCCCGGAACGCGCCGGTGTCGCTGCGCCAGGCGAAGCGCGCCATCGACGGCG GGTTCCACCTGCCGCTCGAGGAGGCGCTCGCGCTGGAGCACCGGATGTACCAGGACTGCCTCGGCACCCGCGACCGGCGC GAGGCGCTGGCCGCGTTCGCCGAGAAGCGCCCGCCGGTGTTCACGGGCGAGTGA
Upstream 100 bases:
>100_bases GTGGCCGCCGGCGCGCTGGCGCAGCGGCTGGTGGGGCGGACCTTGCCGGGCAAGGCGCTCCAGGCGGAGCTGGCGCGGGC GGCGCCGGCAGGAGGCTGAC
Downstream 100 bases:
>100_bases GCCGGGGCGCGCAGCGCGCCGCGAGGACACGACGGGGGAAGGCACCATGGACGCGGACGGAACGCCCGGAGGTGGCGCAG TGGCCCGAGACGAGTCGCCG
Product: Enoyl-CoA hydratase/isomerase
Products: trans(or 3)-enoyl-CoA; H2O [C]
Alternate protein names: NA
Number of amino acids: Translated: 257; Mature: 257
Protein sequence:
>257_residues MDLRVERRDAVEVWTIDGASRRNSITVGLLGALRAQLARAGGDRALRCVVITGDGDKAFCAGADLKERAGMSADDVHRFH EGLRDALRGIEQAPQPFVAALNGAALGGGLELALACDLRVAADSAQLGLPEVALGIIPGGGGTQRLARLVGVARAKDLVL TARRIGAAEALAMGLVTQIAPPGRLLDDALALAGRIARNAPVSLRQAKRAIDGGFHLPLEEALALEHRMYQDCLGTRDRR EALAAFAEKRPPVFTGE
Sequences:
>Translated_257_residues MDLRVERRDAVEVWTIDGASRRNSITVGLLGALRAQLARAGGDRALRCVVITGDGDKAFCAGADLKERAGMSADDVHRFH EGLRDALRGIEQAPQPFVAALNGAALGGGLELALACDLRVAADSAQLGLPEVALGIIPGGGGTQRLARLVGVARAKDLVL TARRIGAAEALAMGLVTQIAPPGRLLDDALALAGRIARNAPVSLRQAKRAIDGGFHLPLEEALALEHRMYQDCLGTRDRR EALAAFAEKRPPVFTGE >Mature_257_residues MDLRVERRDAVEVWTIDGASRRNSITVGLLGALRAQLARAGGDRALRCVVITGDGDKAFCAGADLKERAGMSADDVHRFH EGLRDALRGIEQAPQPFVAALNGAALGGGLELALACDLRVAADSAQLGLPEVALGIIPGGGGTQRLARLVGVARAKDLVL TARRIGAAEALAMGLVTQIAPPGRLLDDALALAGRIARNAPVSLRQAKRAIDGGFHLPLEEALALEHRMYQDCLGTRDRR EALAAFAEKRPPVFTGE
Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]
COG id: COG1024
COG function: function code I; Enoyl-CoA hydratase/carnithine racemase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]
Homologues:
Organism=Homo sapiens, GI194097323, Length=232, Percent_Identity=39.6551724137931, Blast_Score=170, Evalue=9e-43, Organism=Homo sapiens, GI4502327, Length=264, Percent_Identity=43.1818181818182, Blast_Score=167, Evalue=7e-42, Organism=Homo sapiens, GI150378541, Length=242, Percent_Identity=35.9504132231405, Blast_Score=119, Evalue=2e-27, Organism=Homo sapiens, GI68989263, Length=217, Percent_Identity=38.2488479262673, Blast_Score=114, Evalue=1e-25, Organism=Homo sapiens, GI20127408, Length=166, Percent_Identity=36.7469879518072, Blast_Score=104, Evalue=6e-23, Organism=Homo sapiens, GI31542718, Length=250, Percent_Identity=27.2, Blast_Score=103, Evalue=2e-22, Organism=Homo sapiens, GI70995211, Length=244, Percent_Identity=31.9672131147541, Blast_Score=99, Evalue=4e-21, Organism=Homo sapiens, GI221136756, Length=254, Percent_Identity=24.0157480314961, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI221136753, Length=254, Percent_Identity=24.0157480314961, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI221307494, Length=236, Percent_Identity=24.5762711864407, Blast_Score=89, Evalue=4e-18, Organism=Homo sapiens, GI261878539, Length=135, Percent_Identity=41.4814814814815, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI116235487, Length=236, Percent_Identity=24.5762711864407, Blast_Score=85, Evalue=7e-17, Organism=Homo sapiens, GI157694516, Length=240, Percent_Identity=25.8333333333333, Blast_Score=78, Evalue=1e-14, Organism=Homo sapiens, GI37594469, Length=232, Percent_Identity=27.5862068965517, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI213417737, Length=240, Percent_Identity=25.8333333333333, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI37594471, Length=232, Percent_Identity=27.5862068965517, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI62530384, Length=171, Percent_Identity=30.9941520467836, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI25453481, Length=244, Percent_Identity=22.5409836065574, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI51538573, Length=244, Percent_Identity=22.5409836065574, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI4757966, Length=212, Percent_Identity=24.0566037735849, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI51538581, Length=212, Percent_Identity=24.0566037735849, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI157694520, Length=184, Percent_Identity=28.804347826087, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI4757968, Length=244, Percent_Identity=22.1311475409836, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI49355787, Length=244, Percent_Identity=22.1311475409836, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI45643119, Length=213, Percent_Identity=24.8826291079812, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI260275230, Length=213, Percent_Identity=24.8826291079812, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI260274832, Length=213, Percent_Identity=24.8826291079812, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI295842266, Length=169, Percent_Identity=27.810650887574, Blast_Score=64, Evalue=9e-11, Organism=Escherichia coli, GI1787659, Length=256, Percent_Identity=40.234375, Blast_Score=165, Evalue=2e-42, Organism=Escherichia coli, GI221142681, Length=220, Percent_Identity=40.9090909090909, Blast_Score=142, Evalue=1e-35, Organism=Escherichia coli, GI1788597, Length=259, Percent_Identity=32.4324324324324, Blast_Score=119, Evalue=2e-28, Organism=Escherichia coli, GI1788682, Length=196, Percent_Identity=38.7755102040816, Blast_Score=114, Evalue=4e-27, Organism=Escherichia coli, GI87082183, Length=220, Percent_Identity=29.5454545454545, Blast_Score=101, Evalue=6e-23, Organism=Escherichia coli, GI1787660, Length=258, Percent_Identity=35.6589147286822, Blast_Score=99, Evalue=3e-22, Organism=Escherichia coli, GI1790281, Length=138, Percent_Identity=36.9565217391304, Blast_Score=87, Evalue=1e-18, Organism=Caenorhabditis elegans, GI25145438, Length=248, Percent_Identity=38.3064516129032, Blast_Score=179, Evalue=1e-45, Organism=Caenorhabditis elegans, GI17540714, Length=224, Percent_Identity=38.8392857142857, Blast_Score=173, Evalue=7e-44, Organism=Caenorhabditis elegans, GI17554946, Length=231, Percent_Identity=37.2294372294372, Blast_Score=161, Evalue=3e-40, Organism=Caenorhabditis elegans, GI17558304, Length=186, Percent_Identity=38.1720430107527, Blast_Score=119, Evalue=1e-27, Organism=Caenorhabditis elegans, GI25144276, Length=186, Percent_Identity=37.0967741935484, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI17508951, Length=186, Percent_Identity=37.0967741935484, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI17560910, Length=190, Percent_Identity=33.6842105263158, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17536985, Length=267, Percent_Identity=26.5917602996255, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17508953, Length=198, Percent_Identity=36.8686868686869, Blast_Score=103, Evalue=6e-23, Organism=Caenorhabditis elegans, GI17534483, Length=260, Percent_Identity=28.8461538461538, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17549921, Length=204, Percent_Identity=26.9607843137255, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17540306, Length=235, Percent_Identity=28.936170212766, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17535521, Length=254, Percent_Identity=23.6220472440945, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI25144160, Length=194, Percent_Identity=27.8350515463918, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI25144157, Length=194, Percent_Identity=27.8350515463918, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24653139, Length=254, Percent_Identity=44.4881889763779, Blast_Score=198, Evalue=3e-51, Organism=Drosophila melanogaster, GI20129971, Length=247, Percent_Identity=38.4615384615385, Blast_Score=181, Evalue=4e-46, Organism=Drosophila melanogaster, GI24653477, Length=247, Percent_Identity=38.4615384615385, Blast_Score=181, Evalue=4e-46, Organism=Drosophila melanogaster, GI21357171, Length=202, Percent_Identity=34.1584158415842, Blast_Score=95, Evalue=4e-20, Organism=Drosophila melanogaster, GI24650670, Length=244, Percent_Identity=32.7868852459016, Blast_Score=94, Evalue=6e-20, Organism=Drosophila melanogaster, GI19922422, Length=248, Percent_Identity=24.5967741935484, Blast_Score=88, Evalue=7e-18, Organism=Drosophila melanogaster, GI19920382, Length=206, Percent_Identity=29.126213592233, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI28571730, Length=208, Percent_Identity=29.8076923076923, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI28571729, Length=208, Percent_Identity=29.8076923076923, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI24654903, Length=219, Percent_Identity=24.6575342465753, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI19921000, Length=143, Percent_Identity=39.1608391608392, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI24583077, Length=143, Percent_Identity=39.1608391608392, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI24583079, Length=143, Percent_Identity=39.1608391608392, Blast_Score=71, Evalue=7e-13,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR014748 - InterPro: IPR001753 - InterPro: IPR018376 [H]
Pfam domain/function: PF00378 ECH [H]
EC number: 4.2.1.17 [C]
Molecular weight: Translated: 27028; Mature: 27028
Theoretical pI: Translated: 8.35; Mature: 8.35
Prosite motif: PS00166 ENOYL_COA_HYDRATASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDLRVERRDAVEVWTIDGASRRNSITVGLLGALRAQLARAGGDRALRCVVITGDGDKAFC CCCCCCCCCCEEEEEECCCCCCCCEEHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEE AGADLKERAGMSADDVHRFHEGLRDALRGIEQAPQPFVAALNGAALGGGLELALACDLRV CCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCEEEEEEECEEE AADSAQLGLPEVALGIIPGGGGTQRLARLVGVARAKDLVLTARRIGAAEALAMGLVTQIA ECCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC PPGRLLDDALALAGRIARNAPVSLRQAKRAIDGGFHLPLEEALALEHRMYQDCLGTRDRR CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHH EALAAFAEKRPPVFTGE HHHHHHHHCCCCCCCCC >Mature Secondary Structure MDLRVERRDAVEVWTIDGASRRNSITVGLLGALRAQLARAGGDRALRCVVITGDGDKAFC CCCCCCCCCCEEEEEECCCCCCCCEEHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEE AGADLKERAGMSADDVHRFHEGLRDALRGIEQAPQPFVAALNGAALGGGLELALACDLRV CCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCEEEEEEECEEE AADSAQLGLPEVALGIIPGGGGTQRLARLVGVARAKDLVLTARRIGAAEALAMGLVTQIA ECCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC PPGRLLDDALALAGRIARNAPVSLRQAKRAIDGGFHLPLEEALALEHRMYQDCLGTRDRR CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHH EALAAFAEKRPPVFTGE HHHHHHHHCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): 0.05 {crotonyl-CoA}} 0.008 {2-decenoyl-CoA}} [C]
Substrates: (3S)-hydroxyacyl-CoA [C]
Specific reaction: (3S)-hydroxyacyl-CoA = trans(or 3)-enoyl-CoA + H2O [C]
General reaction: addition (of H2O to carbon carbon double bondelimination (of H2O C-O bond cleavagehydration [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9387222; 9384377 [H]