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The map label for this gene is xerD [H]

Identifier: 220917358

GI number: 220917358

Start: 2507903

End: 2508799

Strand: Direct

Name: xerD [H]

Synonym: A2cp1_2258

Alternate gene names: 220917358

Gene position: 2507903-2508799 (Clockwise)

Preceding gene: 220917357

Following gene: 220917359

Centisome position: 49.87

GC content: 74.69

Gene sequence:

>897_bases
ATGTCCGCGCTGGAGCCCGCCCTCGACCTGTTCCTCGCCCACGTGCGCGTGGAGAAGGGGCTCGCCGAGAACAGCGTCGA
GGCCTACGGGCGCGACCTGCGCCGCTACCTCGAGCACCTGGACGAGCTGGGGGTGGACGCCTGGGAGCGGGTGGGCCGCG
GCGAGATCCAGGCCCACCTCGCCGAGCTGGTGCGCCGCGGTCTCTCGCCGCGCTCGCAGGCGCGGGCGCTCTCCGCCATC
CGCTCGCTGCACCGGCTCCTCGCGGCCGAGCGCGTCACTCCCGCCGATCCGTCGGACGAGATCGAGTCGCCGCGGCCCGG
GCGCCGCCTCCCGGGGCTGCTCTCGCACGACGAGGTGGACCGCCTGCTGGCCGCGCCGGACGTGCGCAGCGCCGCCGGCA
TCCGCGACCGCGCCATGCTGGAGCTGCTCTACGCGACCGGGCTGCGCGTCTCGGAGCTGGTCTCGCTGCAGCTCAACGAC
GTGAACCTCGAGACGCGGGTGCTCGTCGCCCGCGGCAAGGGGAACAAGGAGCGGATCGTGCCGGTGGGCGCGCCCGCCGC
CGCGGCGGTGAAGGCGTACCTGGCGGTCGCGCGGGAGCGGCTGCTCCACGGCCGCCGCTCGAAGGACCTGTTCGTCACGC
CGCGGGGCGGCCGGATGACGCGGCAGGGGTTCGCGAAGATCCTGGACCGCTGCGCCCGGCGCGCGGGCATCCGCCGGCGC
ATCTCACCGCACAAGCTGCGCCACTCGTTCGCCACCCACCTGCTGGAGGGGGGCGCCGACCTGCGCGCGGTCCAGGAGAT
GCTGGGCCACGCCGACGTCTCCACCACGCAGATCTACACCCACGTGGATCGCACCCACGTGAAGCGGCTGTACGACCGCT
TCCACCCCCGCGCCTGA

Upstream 100 bases:

>100_bases
GTGGTCCGCGCCGGCAAGGGCGACGTCTCCGACCTGCTCGCCTGAGCGGCGCGCCGGCCGCGAACTGGACGGGCGCGGGC
CCGGCGCTATCGTCGCCGCG

Downstream 100 bases:

>100_bases
GCCGCGCCGCGATCCCGGGCGGAATCGGCGCGCCCCGGCTGTTCGGAGGGGGGAGCGGGCCGCGGTCCCGGCGCGTCCGG
CGGCCGCCGAGCGCGTTGAC

Product: tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MSALEPALDLFLAHVRVEKGLAENSVEAYGRDLRRYLEHLDELGVDAWERVGRGEIQAHLAELVRRGLSPRSQARALSAI
RSLHRLLAAERVTPADPSDEIESPRPGRRLPGLLSHDEVDRLLAAPDVRSAAGIRDRAMLELLYATGLRVSELVSLQLND
VNLETRVLVARGKGNKERIVPVGAPAAAAVKAYLAVARERLLHGRRSKDLFVTPRGGRMTRQGFAKILDRCARRAGIRRR
ISPHKLRHSFATHLLEGGADLRAVQEMLGHADVSTTQIYTHVDRTHVKRLYDRFHPRA

Sequences:

>Translated_298_residues
MSALEPALDLFLAHVRVEKGLAENSVEAYGRDLRRYLEHLDELGVDAWERVGRGEIQAHLAELVRRGLSPRSQARALSAI
RSLHRLLAAERVTPADPSDEIESPRPGRRLPGLLSHDEVDRLLAAPDVRSAAGIRDRAMLELLYATGLRVSELVSLQLND
VNLETRVLVARGKGNKERIVPVGAPAAAAVKAYLAVARERLLHGRRSKDLFVTPRGGRMTRQGFAKILDRCARRAGIRRR
ISPHKLRHSFATHLLEGGADLRAVQEMLGHADVSTTQIYTHVDRTHVKRLYDRFHPRA
>Mature_297_residues
SALEPALDLFLAHVRVEKGLAENSVEAYGRDLRRYLEHLDELGVDAWERVGRGEIQAHLAELVRRGLSPRSQARALSAIR
SLHRLLAAERVTPADPSDEIESPRPGRRLPGLLSHDEVDRLLAAPDVRSAAGIRDRAMLELLYATGLRVSELVSLQLNDV
NLETRVLVARGKGNKERIVPVGAPAAAAVKAYLAVARERLLHGRRSKDLFVTPRGGRMTRQGFAKILDRCARRAGIRRRI
SPHKLRHSFATHLLEGGADLRAVQEMLGHADVSTTQIYTHVDRTHVKRLYDRFHPRA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=292, Percent_Identity=46.5753424657534, Blast_Score=231, Evalue=4e-62,
Organism=Escherichia coli, GI1790244, Length=298, Percent_Identity=37.248322147651, Blast_Score=200, Evalue=1e-52,
Organism=Escherichia coli, GI1790767, Length=183, Percent_Identity=28.9617486338798, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790768, Length=181, Percent_Identity=30.939226519337, Blast_Score=79, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33269; Mature: 33138

Theoretical pI: Translated: 11.05; Mature: 11.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALEPALDLFLAHVRVEKGLAENSVEAYGRDLRRYLEHLDELGVDAWERVGRGEIQAHL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCHHHHHHH
AELVRRGLSPRSQARALSAIRSLHRLLAAERVTPADPSDEIESPRPGRRLPGLLSHDEVD
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
RLLAAPDVRSAAGIRDRAMLELLYATGLRVSELVSLQLNDVNLETRVLVARGKGNKERIV
HHHCCCCCHHHCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEEEEECCCCCCEEE
PVGAPAAAAVKAYLAVARERLLHGRRSKDLFVTPRGGRMTRQGFAKILDRCARRAGIRRR
ECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHC
ISPHKLRHSFATHLLEGGADLRAVQEMLGHADVSTTQIYTHVDRTHVKRLYDRFHPRA
CCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SALEPALDLFLAHVRVEKGLAENSVEAYGRDLRRYLEHLDELGVDAWERVGRGEIQAHL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCHHHHHHH
AELVRRGLSPRSQARALSAIRSLHRLLAAERVTPADPSDEIESPRPGRRLPGLLSHDEVD
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
RLLAAPDVRSAAGIRDRAMLELLYATGLRVSELVSLQLNDVNLETRVLVARGKGNKERIV
HHHCCCCCHHHCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEEEEECCCCCCEEE
PVGAPAAAAVKAYLAVARERLLHGRRSKDLFVTPRGGRMTRQGFAKILDRCARRAGIRRR
ECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHC
ISPHKLRHSFATHLLEGGADLRAVQEMLGHADVSTTQIYTHVDRTHVKRLYDRFHPRA
CCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10537218; 10498718 [H]