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The map label for this gene is ubiB [C]

Identifier: 220917340

GI number: 220917340

Start: 2483674

End: 2485347

Strand: Reverse

Name: ubiB [C]

Synonym: A2cp1_2240

Alternate gene names: 220917340

Gene position: 2485347-2483674 (Counterclockwise)

Preceding gene: 220917342

Following gene: 220917338

Centisome position: 49.42

GC content: 71.92

Gene sequence:

>1674_bases
ATGCTCGGGCGGGCGTTCCAGGATCTCAACCGGCTGCGGCAGATCTCGGCCGCCATGGCCCGCCACGGCTTCGGCGCGTA
CCTCGAGCGGATGCGGCTGCGGGACGTGCTGGGCCGCGACGCGCCGCCGCCGGGAGAGCCCCTCCCGCCCCCGGATCGCA
GCACCGCGGCGCGCTTCCGCACCATGCTCGGGGAGCTCGGGCCCACGTTCATCAAGCTGGGGCAGCTCCTCTCCTCCCGG
CCCGACGTGCTGCCCTCGCACTGGGTCGACGAGCTCGAGAAGCTGCAGGACGCCTGCCCGCCGGTGGGCGTCGCCGAGAT
CCGCGACGAGATCGAGCGCGGCCTGGGCCGCCCCGTGGAGACGCTGTTCGCCGCGCTGGATCCGGTCCCGCTCGCCAGCG
CCTCGATCGCGCAGGTGCACCGCGCCACCACGCACGAGGGCGTGCAGGTGGTGGTGAAGGTCCAGCGCCCGCGCATCCGG
GAGCAGATCGAGTCGGACCTGGCGCTGCTCCACGACCTGGCCGGCCTGCTCGAGGCGGTGATCGAGGAGACCGGCATCTA
CACGCCCACCGGCGTGATGGAGGAGTTCGACCGGACCATCCACGAGGAGCTCGACTTCTCGAACGAGGCCCGCAACGCGA
CCGCCATGTACGAGACGTCGGCCGGCCGCGAGTTCCTGGTGATCCCGCGCGTGCACAAGGCGCTCTCGTGCGACACCGTG
CTCACGCTCGACTACGTGGAGGGCGTGAAGGTCTCCGACGTCACCGCCGAGGCCGGGTTCGACCTCGAGCAGGTGGCCCG
CAACGTCATCGAGGCGTCGTTCCGGCAGCTGTTCGAGGACGGGCTCTTCCACGGCGACCCGCACCCCGGGAACATCCTGG
TGCTGCCGGGGAACCGCATCGCCCTGCTCGACTTCGGCTTGGTGGGCCGCCTGTCGCGCGTGCAGCAGGAGGCGCTCGTC
ACGCTCATCGTGGCGGTGGCGCTGCGCGACCCGGAGACGGTGGCGCGGGTGCTGAACCGGATCGGCGTGCCGGACGCGCG
CGCGCCCATCACCGAGTTCCGCGAGGACATCCGCGTCATCCTCGACCGCTACCTGGGCCTGCGGCTGGACGAGATCCGCA
GCGCCACGCTGCTGCGGGACCTCCTCGACCTCGCCATCCGCCACCGCATCCGCATCCCGAAGGAGTACGCGGTCCTCGCG
AAGGCGTCGGTCACCATCGAGGGCATCATCCGCCGGCTGTACCCGAAGCTCGACATCCTCGAGGTCGGGCTGCCCTACGC
AAAGGAGCTGCTGCTCTCGCGCTTCAACCCGTCCGACGCCTCCGGCCTGGTGATGCGCTCGCTGCTCAAGCTCCAGGGCC
TCGCCGAGGACGTGCCCACCCAGCTCTCGCAGATCCTGGTGGACCTCGAGGGCGGCAAGTTCCGCGTGAACGTCGCCTCC
GACGCCATCGACCGGATCGGCGGCCACGTGCGCGCGCTCGCGGTGCTGGTGTTCCTCGGGCTGCTCGCGGCCGGCCTCAC
CGTGGGGGGGCTGGTGGTGCTGGCGAGCGGCGAGGGCCTGCTGGGCGGGCTCGCGCTGGGCGCTGCGGCGGTGCTGTGCG
CGTTCGCGGCGGCGTACCACCTCGCCACGCTGCGGATGCGCAAGATCTCGCTGCGCCGCTGGCTGAAGCGCTGA

Upstream 100 bases:

>100_bases
CGCGACGGGAACCCCCGGCGGCGCCGTTCGATTCCTCACCCGCGCCTTCGCCCATCGCGCTCGTGGCCACCCCCGGATCC
CGGTGTTACAGTCGCGGGCC

Downstream 100 bases:

>100_bases
GCCGGACGGGGCCGGGTCAGCCGCGCTCCTCCGCGCAGGCGAGCGCGGCGACCGTCCCGAGCCAGGCGAGGTCCACCGCC
GCCGAGACCCCGGCGGCCGC

Product: ABC-1 domain-containing protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 557; Mature: 557

Protein sequence:

>557_residues
MLGRAFQDLNRLRQISAAMARHGFGAYLERMRLRDVLGRDAPPPGEPLPPPDRSTAARFRTMLGELGPTFIKLGQLLSSR
PDVLPSHWVDELEKLQDACPPVGVAEIRDEIERGLGRPVETLFAALDPVPLASASIAQVHRATTHEGVQVVVKVQRPRIR
EQIESDLALLHDLAGLLEAVIEETGIYTPTGVMEEFDRTIHEELDFSNEARNATAMYETSAGREFLVIPRVHKALSCDTV
LTLDYVEGVKVSDVTAEAGFDLEQVARNVIEASFRQLFEDGLFHGDPHPGNILVLPGNRIALLDFGLVGRLSRVQQEALV
TLIVAVALRDPETVARVLNRIGVPDARAPITEFREDIRVILDRYLGLRLDEIRSATLLRDLLDLAIRHRIRIPKEYAVLA
KASVTIEGIIRRLYPKLDILEVGLPYAKELLLSRFNPSDASGLVMRSLLKLQGLAEDVPTQLSQILVDLEGGKFRVNVAS
DAIDRIGGHVRALAVLVFLGLLAAGLTVGGLVVLASGEGLLGGLALGAAAVLCAFAAAYHLATLRMRKISLRRWLKR

Sequences:

>Translated_557_residues
MLGRAFQDLNRLRQISAAMARHGFGAYLERMRLRDVLGRDAPPPGEPLPPPDRSTAARFRTMLGELGPTFIKLGQLLSSR
PDVLPSHWVDELEKLQDACPPVGVAEIRDEIERGLGRPVETLFAALDPVPLASASIAQVHRATTHEGVQVVVKVQRPRIR
EQIESDLALLHDLAGLLEAVIEETGIYTPTGVMEEFDRTIHEELDFSNEARNATAMYETSAGREFLVIPRVHKALSCDTV
LTLDYVEGVKVSDVTAEAGFDLEQVARNVIEASFRQLFEDGLFHGDPHPGNILVLPGNRIALLDFGLVGRLSRVQQEALV
TLIVAVALRDPETVARVLNRIGVPDARAPITEFREDIRVILDRYLGLRLDEIRSATLLRDLLDLAIRHRIRIPKEYAVLA
KASVTIEGIIRRLYPKLDILEVGLPYAKELLLSRFNPSDASGLVMRSLLKLQGLAEDVPTQLSQILVDLEGGKFRVNVAS
DAIDRIGGHVRALAVLVFLGLLAAGLTVGGLVVLASGEGLLGGLALGAAAVLCAFAAAYHLATLRMRKISLRRWLKR
>Mature_557_residues
MLGRAFQDLNRLRQISAAMARHGFGAYLERMRLRDVLGRDAPPPGEPLPPPDRSTAARFRTMLGELGPTFIKLGQLLSSR
PDVLPSHWVDELEKLQDACPPVGVAEIRDEIERGLGRPVETLFAALDPVPLASASIAQVHRATTHEGVQVVVKVQRPRIR
EQIESDLALLHDLAGLLEAVIEETGIYTPTGVMEEFDRTIHEELDFSNEARNATAMYETSAGREFLVIPRVHKALSCDTV
LTLDYVEGVKVSDVTAEAGFDLEQVARNVIEASFRQLFEDGLFHGDPHPGNILVLPGNRIALLDFGLVGRLSRVQQEALV
TLIVAVALRDPETVARVLNRIGVPDARAPITEFREDIRVILDRYLGLRLDEIRSATLLRDLLDLAIRHRIRIPKEYAVLA
KASVTIEGIIRRLYPKLDILEVGLPYAKELLLSRFNPSDASGLVMRSLLKLQGLAEDVPTQLSQILVDLEGGKFRVNVAS
DAIDRIGGHVRALAVLVFLGLLAAGLTVGGLVVLASGEGLLGGLALGAAAVLCAFAAAYHLATLRMRKISLRRWLKR

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI40254938, Length=284, Percent_Identity=33.4507042253521, Blast_Score=156, Evalue=5e-38,
Organism=Homo sapiens, GI41393593, Length=285, Percent_Identity=35.7894736842105, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI217035081, Length=238, Percent_Identity=32.7731092436975, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI34147522, Length=318, Percent_Identity=26.4150943396226, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI27363457, Length=344, Percent_Identity=25.2906976744186, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI217416386, Length=300, Percent_Identity=26, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI2367309, Length=501, Percent_Identity=30.938123752495, Blast_Score=204, Evalue=9e-54,
Organism=Caenorhabditis elegans, GI17559152, Length=316, Percent_Identity=29.4303797468354, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI32565180, Length=246, Percent_Identity=28.0487804878049, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17555620, Length=309, Percent_Identity=23.9482200647249, Blast_Score=84, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323282, Length=241, Percent_Identity=30.2904564315353, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6321319, Length=245, Percent_Identity=27.7551020408163, Blast_Score=88, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6325148, Length=432, Percent_Identity=21.2962962962963, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24662575, Length=286, Percent_Identity=29.7202797202797, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI22024280, Length=249, Percent_Identity=30.9236947791165, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI18859849, Length=261, Percent_Identity=28.3524904214559, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 61103; Mature: 61103

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS00589 PTS_HPR_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGRAFQDLNRLRQISAAMARHGFGAYLERMRLRDVLGRDAPPPGEPLPPPDRSTAARFR
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHH
TMLGELGPTFIKLGQLLSSRPDVLPSHWVDELEKLQDACPPVGVAEIRDEIERGLGRPVE
HHHHHHCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHH
TLFAALDPVPLASASIAQVHRATTHEGVQVVVKVQRPRIREQIESDLALLHDLAGLLEAV
HHHHHHCCCCCCHHHHHHHHHHHHHCCHHEEEEHHCHHHHHHHHHHHHHHHHHHHHHHHH
IEETGIYTPTGVMEEFDRTIHEELDFSNEARNATAMYETSAGREFLVIPRVHKALSCDTV
HHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHEEECCCCCEEEEECHHHHHHCCCCE
LTLDYVEGVKVSDVTAEAGFDLEQVARNVIEASFRQLFEDGLFHGDPHPGNILVLPGNRI
EEEHHHCCCEEECCCHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCEE
ALLDFGLVGRLSRVQQEALVTLIVAVALRDPETVARVLNRIGVPDARAPITEFREDIRVI
EEEECHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
LDRYLGLRLDEIRSATLLRDLLDLAIRHRIRIPKEYAVLAKASVTIEGIIRRLYPKLDIL
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHH
EVGLPYAKELLLSRFNPSDASGLVMRSLLKLQGLAEDVPTQLSQILVDLEGGKFRVNVAS
HCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHH
DAIDRIGGHVRALAVLVFLGLLAAGLTVGGLVVLASGEGLLGGLALGAAAVLCAFAAAYH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
LATLRMRKISLRRWLKR
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLGRAFQDLNRLRQISAAMARHGFGAYLERMRLRDVLGRDAPPPGEPLPPPDRSTAARFR
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHH
TMLGELGPTFIKLGQLLSSRPDVLPSHWVDELEKLQDACPPVGVAEIRDEIERGLGRPVE
HHHHHHCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHH
TLFAALDPVPLASASIAQVHRATTHEGVQVVVKVQRPRIREQIESDLALLHDLAGLLEAV
HHHHHHCCCCCCHHHHHHHHHHHHHCCHHEEEEHHCHHHHHHHHHHHHHHHHHHHHHHHH
IEETGIYTPTGVMEEFDRTIHEELDFSNEARNATAMYETSAGREFLVIPRVHKALSCDTV
HHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHEEECCCCCEEEEECHHHHHHCCCCE
LTLDYVEGVKVSDVTAEAGFDLEQVARNVIEASFRQLFEDGLFHGDPHPGNILVLPGNRI
EEEHHHCCCEEECCCHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCEE
ALLDFGLVGRLSRVQQEALVTLIVAVALRDPETVARVLNRIGVPDARAPITEFREDIRVI
EEEECHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
LDRYLGLRLDEIRSATLLRDLLDLAIRHRIRIPKEYAVLAKASVTIEGIIRRLYPKLDIL
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHH
EVGLPYAKELLLSRFNPSDASGLVMRSLLKLQGLAEDVPTQLSQILVDLEGGKFRVNVAS
HCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHH
DAIDRIGGHVRALAVLVFLGLLAAGLTVGGLVVLASGEGLLGGLALGAAAVLCAFAAAYH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
LATLRMRKISLRRWLKR
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA