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The map label for this gene is dcuB [H]

Identifier: 220917279

GI number: 220917279

Start: 2420664

End: 2422025

Strand: Direct

Name: dcuB [H]

Synonym: A2cp1_2178

Alternate gene names: 220917279

Gene position: 2420664-2422025 (Clockwise)

Preceding gene: 220917278

Following gene: 220917280

Centisome position: 48.13

GC content: 71.22

Gene sequence:

>1362_bases
ATGATCTGGCTCCAGCTCGTGGTGGTCCTCGCCGCCATCTTCATCGGCGCCCGGCTCGGCGGCATCGGCCTGGGCGTGAT
GGGCGGCCTCGGCCTCGGCGTCCTCACCTTCGGCTTCCACCTGCAGCCCACCTCGCCGCCGATCGACGTGCTCCTCATGA
TCGCGGCGGTGGTCACCGCCGCCGGCGTGCTGCAGGCGGCCGGCGGGCTCGACTACCTGGTCTCGGTGGCGGAGCGCATC
CTCCGCAGCAACCCGGACCGGATCACGTTCCTCGGGCCGCTCGTCACGTACGTGTTCACGCTGTTCGCCGGCACCGGCCA
CGTCGCCTACTCGGTGCTGCCGGTGATCTCGGAGGTGGCGCGCGAGACCGGGGTCCGCCCGGAGCGCCCCATGTCCATCT
CGGTGATCGCCTCGCAGCAGGCCATCACCGCCAGCCCCATCTCCGCCGCCACCGTGGCGCTGCTGGGCATGCTCTCCACC
GGCGCCGCCGGCGCGGCGTTCCACGTCGAGCTCATCGACATCCTGAAGGTCTGCATCCCGTCCACGCTGCTCGGCGTGCT
GGTGGCCGCGTTCGTCGCCAACCGGATGGGCAAGGACCTGGACCAGGATCCCGAGTACCAGGACCGCGTGGCGCGCGGGC
TCGCCGCGCCCGCCGGCCATCAGGCCCTCGCCGGCGCCGACGGCGGCACCCCGGTCCGCGTCGCCGCGCCGGTCACGGCG
AAGATCGCGGTGGGGATCTTCCTCGCGGCGGCGCTCGCGGTGGTGCTGTTCGGCTCGTTCCCCGGGATGCGCCCGGAGTG
GACCACCGCGAGCGGCGTCACCAAGCTCGGCATGCCGCACACCATCGAGATGGTGATGCTCTCGGCGGCGGCGCTCATGC
TGATGGTCTGCCGGGTGGACGTCTCGAAGGTCGCGACCGGCAGCGTGTTCGGGGCCGGCGTGCAGGCGGTGATCGCCATC
TTCGGCATCGCGTGGATGGGCGACACGTTCTTCGCCGGCAACATGGAGGTGCTGGGCGGCAGCATCAAGGGCATGGTCAC
CGCCGCGCCCTGGCTGTTCGCGGCCGCGCTGTTCGCGCTCTCCGTGCTGCTCTACAGCCAGGCCGCCACCGTGCGCGCGC
TCATGCCGCTCGGGATCGCCCTCGGCATCCCCGCGCCCGCGCTCATGGCGATGTTCCCGGCGGTGAACGGGTACTTCTTC
ATCCCCAACTACCCGACCATCGTCGCGGCCATCAACTTCGACCGCACCGGGACGACGCGCATCGGGCGCTGGGTGCTGAA
CCACAGCTTCATGGTCCCCGGCCTGATCTCGACGGTGGTCGCGATCGCCACCGGGCTCGTCATCGTCCGCTTCGTGTTCT
GA

Upstream 100 bases:

>100_bases
TCTCGAAGGAGCTGCTCGACGAGGTGCTCTCCACCGAGAACCTGCTCCGCCCCCGCTACATCAACCCGCGCCTGCAGAAG
GTCGCGTAGGCGGCGCCGCC

Downstream 100 bases:

>100_bases
CCCGCAGCCCGCACCGCCACCTGAGAGAGAGGAAGCCATGAGACCGCTCGTCTCGGCAGCGCTCTTCGCCTGCCTCGTCG
CCGCCCGCCCCGCCGCCGCG

Product: anaerobic C4-dicarboxylate transporter

Products: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MIWLQLVVVLAAIFIGARLGGIGLGVMGGLGLGVLTFGFHLQPTSPPIDVLLMIAAVVTAAGVLQAAGGLDYLVSVAERI
LRSNPDRITFLGPLVTYVFTLFAGTGHVAYSVLPVISEVARETGVRPERPMSISVIASQQAITASPISAATVALLGMLST
GAAGAAFHVELIDILKVCIPSTLLGVLVAAFVANRMGKDLDQDPEYQDRVARGLAAPAGHQALAGADGGTPVRVAAPVTA
KIAVGIFLAAALAVVLFGSFPGMRPEWTTASGVTKLGMPHTIEMVMLSAAALMLMVCRVDVSKVATGSVFGAGVQAVIAI
FGIAWMGDTFFAGNMEVLGGSIKGMVTAAPWLFAAALFALSVLLYSQAATVRALMPLGIALGIPAPALMAMFPAVNGYFF
IPNYPTIVAAINFDRTGTTRIGRWVLNHSFMVPGLISTVVAIATGLVIVRFVF

Sequences:

>Translated_453_residues
MIWLQLVVVLAAIFIGARLGGIGLGVMGGLGLGVLTFGFHLQPTSPPIDVLLMIAAVVTAAGVLQAAGGLDYLVSVAERI
LRSNPDRITFLGPLVTYVFTLFAGTGHVAYSVLPVISEVARETGVRPERPMSISVIASQQAITASPISAATVALLGMLST
GAAGAAFHVELIDILKVCIPSTLLGVLVAAFVANRMGKDLDQDPEYQDRVARGLAAPAGHQALAGADGGTPVRVAAPVTA
KIAVGIFLAAALAVVLFGSFPGMRPEWTTASGVTKLGMPHTIEMVMLSAAALMLMVCRVDVSKVATGSVFGAGVQAVIAI
FGIAWMGDTFFAGNMEVLGGSIKGMVTAAPWLFAAALFALSVLLYSQAATVRALMPLGIALGIPAPALMAMFPAVNGYFF
IPNYPTIVAAINFDRTGTTRIGRWVLNHSFMVPGLISTVVAIATGLVIVRFVF
>Mature_453_residues
MIWLQLVVVLAAIFIGARLGGIGLGVMGGLGLGVLTFGFHLQPTSPPIDVLLMIAAVVTAAGVLQAAGGLDYLVSVAERI
LRSNPDRITFLGPLVTYVFTLFAGTGHVAYSVLPVISEVARETGVRPERPMSISVIASQQAITASPISAATVALLGMLST
GAAGAAFHVELIDILKVCIPSTLLGVLVAAFVANRMGKDLDQDPEYQDRVARGLAAPAGHQALAGADGGTPVRVAAPVTA
KIAVGIFLAAALAVVLFGSFPGMRPEWTTASGVTKLGMPHTIEMVMLSAAALMLMVCRVDVSKVATGSVFGAGVQAVIAI
FGIAWMGDTFFAGNMEVLGGSIKGMVTAAPWLFAAALFALSVLLYSQAATVRALMPLGIALGIPAPALMAMFPAVNGYFF
IPNYPTIVAAINFDRTGTTRIGRWVLNHSFMVPGLISTVVAIATGLVIVRFVF

Specific function: Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane [H]

COG id: COG2704

COG function: function code R; Anaerobic C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuA/dcuB transporter (TC 2.A.13.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790580, Length=460, Percent_Identity=41.9565217391304, Blast_Score=313, Evalue=1e-86,
Organism=Escherichia coli, GI1790565, Length=411, Percent_Identity=40.3892944038929, Blast_Score=301, Evalue=7e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004668 [H]

Pfam domain/function: PF03605 DcuA_DcuB [H]

EC number: NA

Molecular weight: Translated: 46799; Mature: 46799

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIWLQLVVVLAAIFIGARLGGIGLGVMGGLGLGVLTFGFHLQPTSPPIDVLLMIAAVVTA
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEECCCCCHHHHHHHHHHHHHH
AGVLQAAGGLDYLVSVAERILRSNPDRITFLGPLVTYVFTLFAGTGHVAYSVLPVISEVA
HHHHHHCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RETGVRPERPMSISVIASQQAITASPISAATVALLGMLSTGAAGAAFHVELIDILKVCIP
HHCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
STLLGVLVAAFVANRMGKDLDQDPEYQDRVARGLAAPAGHQALAGADGGTPVRVAAPVTA
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCHHH
KIAVGIFLAAALAVVLFGSFPGMRPEWTTASGVTKLGMPHTIEMVMLSAAALMLMVCRVD
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHH
VSKVATGSVFGAGVQAVIAIFGIAWMGDTFFAGNMEVLGGSIKGMVTAAPWLFAAALFAL
HHHHHCCCHHHHHHHHHHHHHHHHHHCCEEECCCHHHHCCCHHHHHHHHHHHHHHHHHHH
SVLLYSQAATVRALMPLGIALGIPAPALMAMFPAVNGYFFIPNYPTIVAAINFDRTGTTR
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEECCCCCEEEEEEECCCCCCHH
IGRWVLNHSFMVPGLISTVVAIATGLVIVRFVF
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIWLQLVVVLAAIFIGARLGGIGLGVMGGLGLGVLTFGFHLQPTSPPIDVLLMIAAVVTA
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEECCCCCHHHHHHHHHHHHHH
AGVLQAAGGLDYLVSVAERILRSNPDRITFLGPLVTYVFTLFAGTGHVAYSVLPVISEVA
HHHHHHCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RETGVRPERPMSISVIASQQAITASPISAATVALLGMLSTGAAGAAFHVELIDILKVCIP
HHCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
STLLGVLVAAFVANRMGKDLDQDPEYQDRVARGLAAPAGHQALAGADGGTPVRVAAPVTA
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCHHH
KIAVGIFLAAALAVVLFGSFPGMRPEWTTASGVTKLGMPHTIEMVMLSAAALMLMVCRVD
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHH
VSKVATGSVFGAGVQAVIAIFGIAWMGDTFFAGNMEVLGGSIKGMVTAAPWLFAAALFAL
HHHHHCCCHHHHHHHHHHHHHHHHHHCCEEECCCHHHHCCCHHHHHHHHHHHHHHHHHHH
SVLLYSQAATVRALMPLGIALGIPAPALMAMFPAVNGYFFIPNYPTIVAAINFDRTGTTR
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEECCCCCEEEEEEECCCCCCHH
IGRWVLNHSFMVPGLISTVVAIATGLVIVRFVF
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Specific reaction: C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] = C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]