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The map label for this gene is yabD [H]

Identifier: 220917209

GI number: 220917209

Start: 2348498

End: 2349274

Strand: Direct

Name: yabD [H]

Synonym: A2cp1_2106

Alternate gene names: 220917209

Gene position: 2348498-2349274 (Clockwise)

Preceding gene: 220917208

Following gene: 220917210

Centisome position: 46.7

GC content: 79.15

Gene sequence:

>777_bases
GTGATCGACTCGCACTGCCACCTCGACGCGCGCGCGTTCGACGCGGACCGGGCCGAGGCGCTGGCCCGGGCGCGCGCCGC
GGGGGTCACCGACGTGATCGTGCCGGCGGTGGGGCCGGATGCCTGGGCGCCGCTGGCGGCGTGGGCCGCCGCGACGCCGG
GCGTCCACCACGGCCTCGGCATCCACCCGCAGCTCCTGCCGGAGCTCGATCCCGGCGGCGACGACCGCCGGCTCGCCGAT
CTCGAGGCCGCGCTCTCGCGCGGTGGCGCGGTGGCGGTCGGGGAGTGCGGGCTCGACGCGCCGAGCGTCGAGGCGGGCGC
GCCCATGGACCGCCAGGTGGCGGTGCTGCGCGGCCACCTGGCGCTGGCGCGCCGCTTCCGGCTGCCCGTGATCCTGCACT
GCCTGCGGGCGCACGAGCCGCTCCTGGCGCTCCTCGCCGAGGCGCCGCTCCCCGCGGGCGGCGTGCTGCACAGCTTCTCC
GGCAGCGCCGACCAGGTCCGCGCCTACCTGCCCTCGGGCCTGCACTTCTCCTTCGCCGGCCCGCTCACCTACGAGCGCGC
CCGGAGGCCCATCGACGCCGCGCGGGCGGTGCCGCGGGACCGGCTGCTCGTGGAGACCGACGCGCCCGACCAGACCCCGC
GCCCCAACCGCGGCCGCAACGAGCCCGCCTACCTCCCCGGCATCCTGTCCGCGCTGGCGGGCGCGCTCGGCACCGGCGCG
GCGGAGGCCGACGCGCTCACCACCGCGAACGCCCGCGCGCTGTTCCGGCTCGCTTGA

Upstream 100 bases:

>100_bases
CGAGCGACCACCGCGTGGTGGACGGGCACGAGGCGGCCGCGTTCACCTACCAGGTGATCAGGTACCTCGAGGATCCCAAC
CTGCTGTTCATGCAGATGGT

Downstream 100 bases:

>100_bases
GCGGCGCGCGAGGCCGCGCTACACCGGGCCCGCATGGCCGGCGACCGCCCCGTCTCCCCCCGCCTCGATCGCACCGCGCG
GCTGCTCGGGCTCGAGGCCA

Product: TatD-related deoxyribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MIDSHCHLDARAFDADRAEALARARAAGVTDVIVPAVGPDAWAPLAAWAAATPGVHHGLGIHPQLLPELDPGGDDRRLAD
LEAALSRGGAVAVGECGLDAPSVEAGAPMDRQVAVLRGHLALARRFRLPVILHCLRAHEPLLALLAEAPLPAGGVLHSFS
GSADQVRAYLPSGLHFSFAGPLTYERARRPIDAARAVPRDRLLVETDAPDQTPRPNRGRNEPAYLPGILSALAGALGTGA
AEADALTTANARALFRLA

Sequences:

>Translated_258_residues
MIDSHCHLDARAFDADRAEALARARAAGVTDVIVPAVGPDAWAPLAAWAAATPGVHHGLGIHPQLLPELDPGGDDRRLAD
LEAALSRGGAVAVGECGLDAPSVEAGAPMDRQVAVLRGHLALARRFRLPVILHCLRAHEPLLALLAEAPLPAGGVLHSFS
GSADQVRAYLPSGLHFSFAGPLTYERARRPIDAARAVPRDRLLVETDAPDQTPRPNRGRNEPAYLPGILSALAGALGTGA
AEADALTTANARALFRLA
>Mature_258_residues
MIDSHCHLDARAFDADRAEALARARAAGVTDVIVPAVGPDAWAPLAAWAAATPGVHHGLGIHPQLLPELDPGGDDRRLAD
LEAALSRGGAVAVGECGLDAPSVEAGAPMDRQVAVLRGHLALARRFRLPVILHCLRAHEPLLALLAEAPLPAGGVLHSFS
GSADQVRAYLPSGLHFSFAGPLTYERARRPIDAARAVPRDRLLVETDAPDQTPRPNRGRNEPAYLPGILSALAGALGTGA
AEADALTTANARALFRLA

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI14042943, Length=268, Percent_Identity=25.7462686567164, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI225903439, Length=234, Percent_Identity=26.4957264957265, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI225903424, Length=234, Percent_Identity=28.6324786324786, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI110349730, Length=267, Percent_Identity=30.3370786516854, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI110349734, Length=267, Percent_Identity=29.5880149812734, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI226061853, Length=273, Percent_Identity=29.6703296703297, Blast_Score=75, Evalue=8e-14,
Organism=Escherichia coli, GI87082439, Length=260, Percent_Identity=35.3846153846154, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1787342, Length=267, Percent_Identity=34.0823970037453, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI48994985, Length=266, Percent_Identity=31.5789473684211, Blast_Score=106, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17559024, Length=286, Percent_Identity=25.5244755244755, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71980746, Length=265, Percent_Identity=25.6603773584906, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI221330018, Length=283, Percent_Identity=26.8551236749117, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24586117, Length=283, Percent_Identity=26.8551236749117, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24648690, Length=295, Percent_Identity=26.1016949152542, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.- [C]

Molecular weight: Translated: 26893; Mature: 26893

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS01137 TATD_1 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDSHCHLDARAFDADRAEALARARAAGVTDVIVPAVGPDAWAPLAAWAAATPGVHHGLG
CCCCCCCCCHHHCCHHHHHHHHHHHHCCCHHEEEECCCCCHHHHHHHHHHCCCCCCCCCC
IHPQLLPELDPGGDDRRLADLEAALSRGGAVAVGECGLDAPSVEAGAPMDRQVAVLRGHL
CCHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHH
ALARRFRLPVILHCLRAHEPLLALLAEAPLPAGGVLHSFSGSADQVRAYLPSGLHFSFAG
HHHHHHCHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHCCCCCHHHHHHHCCCCCEEEECC
PLTYERARRPIDAARAVPRDRLLVETDAPDQTPRPNRGRNEPAYLPGILSALAGALGTGA
CCCHHHHCCCHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
AEADALTTANARALFRLA
CHHHHHHCCCCCEEEECC
>Mature Secondary Structure
MIDSHCHLDARAFDADRAEALARARAAGVTDVIVPAVGPDAWAPLAAWAAATPGVHHGLG
CCCCCCCCCHHHCCHHHHHHHHHHHHCCCHHEEEECCCCCHHHHHHHHHHCCCCCCCCCC
IHPQLLPELDPGGDDRRLADLEAALSRGGAVAVGECGLDAPSVEAGAPMDRQVAVLRGHL
CCHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHH
ALARRFRLPVILHCLRAHEPLLALLAEAPLPAGGVLHSFSGSADQVRAYLPSGLHFSFAG
HHHHHHCHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHCCCCCHHHHHHHCCCCCEEEECC
PLTYERARRPIDAARAVPRDRLLVETDAPDQTPRPNRGRNEPAYLPGILSALAGALGTGA
CCCHHHHCCCHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
AEADALTTANARALFRLA
CHHHHHHCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]