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The map label for this gene is rpfG [H]

Identifier: 220917204

GI number: 220917204

Start: 2342755

End: 2343828

Strand: Reverse

Name: rpfG [H]

Synonym: A2cp1_2101

Alternate gene names: 220917204

Gene position: 2343828-2342755 (Counterclockwise)

Preceding gene: 220917213

Following gene: 220917203

Centisome position: 46.6

GC content: 71.23

Gene sequence:

>1074_bases
ATGACGGAGATCGCCCCCGAAGCCACCCGGATCCTCATCGTGGACGACGACGCCGCGGTCCGGGACGTCATCACGGTGCT
CCTGCGGGAAGAAGGCTACGTCTGCACCACCGTGGCGAGCGCCGAGGCGGCGCTCGACGAGGCGCGCAAGACCGACTACC
CGCTCGTCATCAGCGACGTGCGGATGCCGGCGCGCGACGGGTTCTGGCTGCTCGAGCAGATGCGCGAGGCCTCGCCCGAC
ACCGCGGTCATCATGCTGACCGCCTACGGCGACACCGAGGCGGCGGTCGAGTGCCTGCGCAACGGCGCGGCGGACTACCT
GCTGAAGCCGCCCAAGGTCACCGAGCTGATCCGGGCGATCGAGCGGGCGCTCGGCCGGCGGCGCCTGGAGCTGGCGCGCG
GGCGGTACCGCCGCAGCCTCGAGAACCGGGTCAAGGAGAAGACCGCCGAGCTCTCCCGCACCCTGCACGACCTCGAGAGC
ACCTACTCGCAGACGCTCTGGACGCTGGTGGCGGCGCTCGACGCGCGAGAGCACGAGACCAGCGATCACTCGCAGCGGGT
GGTGCGCTACACGCTCGCCATCGCGCGCCGGGTGGGGCTCGCAGAGACCGCGCTCCCCGACGTGGGCCGCGGCGCGCTGC
TGCACGACATCGGCAAGATCGGCGTGCCCGACGCGATCCTGCTGAAGCCGGGGAAGCTGACGCCGGAGGAGTGGACCGAG
ATGCGGAAGCACCCGCAGATCGGCTTCAACATCCTGAAGAGCGTCGACTTCCTGCAGGTGCCCGCCGAGATGGTGCTCTG
CCACCAGGAGCGCTTCGACGGCGGCGGCTACCCGCGCGGCCTCTCCGGCGACGCCATCCCGCTCTCGGCGCGCATCTTCG
CGATCGCCGACTGCTTCGACGCGATGACCAGCGACCGGCCCTACCGCAAGCGCACCTCCACCGAGAACGCGCGCAAGGAG
ATCCTGCGCTGCGCGGGGACGCAGTTCGACCCGCGCGCCGCCGACGCGTTCCTGTCGCTCGGCGAGGACGAGCTCCTGGA
GCTGTCGCGACCGTCGGACGAGCGGCCCATCTGA

Upstream 100 bases:

>100_bases
CGCCCGCCCTCTGCTACCCTACACATTGGGGAGCGTACCTGCATGCTATACTCCGCGCGCTTCTCCCCTCTTGGGTTCGC
CCAGTCCGCCCCGGTTACCA

Downstream 100 bases:

>100_bases
CGCTCCGCGCGGCGGGCGGCGCTGCGCGGGCCCGCGCAGGCGTCCCGGTGGCTTTCTCCTCCCCCCGCGGTGGTGGTATG
AGGCGCCGTGCTCCAGCAAC

Product: response regulator receiver modulated metal dependent phosphohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MTEIAPEATRILIVDDDAAVRDVITVLLREEGYVCTTVASAEAALDEARKTDYPLVISDVRMPARDGFWLLEQMREASPD
TAVIMLTAYGDTEAAVECLRNGAADYLLKPPKVTELIRAIERALGRRRLELARGRYRRSLENRVKEKTAELSRTLHDLES
TYSQTLWTLVAALDAREHETSDHSQRVVRYTLAIARRVGLAETALPDVGRGALLHDIGKIGVPDAILLKPGKLTPEEWTE
MRKHPQIGFNILKSVDFLQVPAEMVLCHQERFDGGGYPRGLSGDAIPLSARIFAIADCFDAMTSDRPYRKRTSTENARKE
ILRCAGTQFDPRAADAFLSLGEDELLELSRPSDERPI

Sequences:

>Translated_357_residues
MTEIAPEATRILIVDDDAAVRDVITVLLREEGYVCTTVASAEAALDEARKTDYPLVISDVRMPARDGFWLLEQMREASPD
TAVIMLTAYGDTEAAVECLRNGAADYLLKPPKVTELIRAIERALGRRRLELARGRYRRSLENRVKEKTAELSRTLHDLES
TYSQTLWTLVAALDAREHETSDHSQRVVRYTLAIARRVGLAETALPDVGRGALLHDIGKIGVPDAILLKPGKLTPEEWTE
MRKHPQIGFNILKSVDFLQVPAEMVLCHQERFDGGGYPRGLSGDAIPLSARIFAIADCFDAMTSDRPYRKRTSTENARKE
ILRCAGTQFDPRAADAFLSLGEDELLELSRPSDERPI
>Mature_356_residues
TEIAPEATRILIVDDDAAVRDVITVLLREEGYVCTTVASAEAALDEARKTDYPLVISDVRMPARDGFWLLEQMREASPDT
AVIMLTAYGDTEAAVECLRNGAADYLLKPPKVTELIRAIERALGRRRLELARGRYRRSLENRVKEKTAELSRTLHDLEST
YSQTLWTLVAALDAREHETSDHSQRVVRYTLAIARRVGLAETALPDVGRGALLHDIGKIGVPDAILLKPGKLTPEEWTEM
RKHPQIGFNILKSVDFLQVPAEMVLCHQERFDGGGYPRGLSGDAIPLSARIFAIADCFDAMTSDRPYRKRTSTENARKEI
LRCAGTQFDPRAADAFLSLGEDELLELSRPSDERPI

Specific function: Positively regulates the synthesis of extracellular enzymes and extracellular polysaccharides. The cell-cell signaling system encoded by rpf genes is required for full virulence and is implicated in regulation of the formation and dispersal of biofilms [H

COG id: COG3437

COG function: function code KT; Response regulator containing a CheY-like receiver domain and an HD-GYP domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=116, Percent_Identity=38.7931034482759, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1790299, Length=114, Percent_Identity=36.8421052631579, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788550, Length=116, Percent_Identity=38.7931034482759, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI87082012, Length=108, Percent_Identity=37.962962962963, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789809, Length=125, Percent_Identity=32.8, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788905, Length=115, Percent_Identity=34.7826086956522, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790552, Length=119, Percent_Identity=35.2941176470588, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786784, Length=118, Percent_Identity=33.0508474576271, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786599, Length=121, Percent_Identity=29.7520661157025, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR003607
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 39842; Mature: 39711

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEIAPEATRILIVDDDAAVRDVITVLLREEGYVCTTVASAEAALDEARKTDYPLVISDV
CCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCCCEEEECC
RMPARDGFWLLEQMREASPDTAVIMLTAYGDTEAAVECLRNGAADYLLKPPKVTELIRAI
CCCCCCCHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHCCCHHHCCCCCCHHHHHHHH
ERALGRRRLELARGRYRRSLENRVKEKTAELSRTLHDLESTYSQTLWTLVAALDAREHET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SDHSQRVVRYTLAIARRVGLAETALPDVGRGALLHDIGKIGVPDAILLKPGKLTPEEWTE
CHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCHHHHHHHHCCCCCEEEECCCCCCHHHHHH
MRKHPQIGFNILKSVDFLQVPAEMVLCHQERFDGGGYPRGLSGDAIPLSARIFAIADCFD
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
AMTSDRPYRKRTSTENARKEILRCAGTQFDPRAADAFLSLGEDELLELSRPSDERPI
HHHCCCCCHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TEIAPEATRILIVDDDAAVRDVITVLLREEGYVCTTVASAEAALDEARKTDYPLVISDV
CCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCCCEEEECC
RMPARDGFWLLEQMREASPDTAVIMLTAYGDTEAAVECLRNGAADYLLKPPKVTELIRAI
CCCCCCCHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHCCCHHHCCCCCCHHHHHHHH
ERALGRRRLELARGRYRRSLENRVKEKTAELSRTLHDLESTYSQTLWTLVAALDAREHET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SDHSQRVVRYTLAIARRVGLAETALPDVGRGALLHDIGKIGVPDAILLKPGKLTPEEWTE
CHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCHHHHHHHHCCCCCEEEECCCCCCHHHHHH
MRKHPQIGFNILKSVDFLQVPAEMVLCHQERFDGGGYPRGLSGDAIPLSARIFAIADCFD
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
AMTSDRPYRKRTSTENARKEILRCAGTQFDPRAADAFLSLGEDELLELSRPSDERPI
HHHCCCCCHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11123673 [H]