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The map label for this gene is arpC [H]

Identifier: 220917047

GI number: 220917047

Start: 2197699

End: 2199171

Strand: Reverse

Name: arpC [H]

Synonym: A2cp1_1943

Alternate gene names: 220917047

Gene position: 2199171-2197699 (Counterclockwise)

Preceding gene: 220917048

Following gene: 220917046

Centisome position: 43.73

GC content: 81.4

Gene sequence:

>1473_bases
ATGGCCGCCCCCCGCGCCCGCACCGCCGCCGTCCTCGCGCTGCTCCTGCCCGCGAGCGGCTGCGCCACGCTGGCGCCGTC
GGGCTTCGTGGACGGACGCACCGCGCCGCCGCCGGAGGTGGCGCGCCGGGCCGCGACCGAGCCCGCACCGGCGCGCGCTG
CCGCCGGGCCGGCCCCGTCGCCGCCCTCCCCCGCGCCCGCCGCGCCGCGCTCGATCCCGGAGCTGGTCGCCCGCGCGCTG
GAGGTCGACCCCGCCACCCGCGCCGCCTGGCACGACGCGCGCGCCGCCGCTGCAGCCGCCGGCGGCGAGCGCACCGCGTA
CCTGCCCTCGGTGTCGGTCGGCGCCGGCCTCCAGCGCGCCGAGACCGCGCGGACGCTGACGCGCGCCGGCACCACCGCCA
CCACCGCCGGGCCATCCGGCGAGCTCACCTGGATCCTGCTCGACCTGGGCGCGCGCGCGGCGCGGGTGGAACAGGCCGAC
CAGCTCCTCCTCGCGTCGCGGCTCGCCGAGCACGCGGCGGTCGCCGATCTGGTGCTGCGCGTCCAGGAGACCGCCTACCA
GTACCTGGGCAGCCGCGCGCTGGTCGAGGCGGAGGCCGCGGCGGTGAAGCAGGCCGAGGAGAGCCTCGCCGCCGCCGAGG
GACGGCGCGGCGCCGGGGTGGCCACCGTCGCGGACGTCCTTCAGGCCCGCACCGCGCGCTCGCAGGCGCGCCTGCGGCTG
CAGCAGCTCGAGGGCCAGGCGCTCACCGTCGGCGGCGCGCTCGCCACGCTCGCGGGGCTCCCGCCCACCGCCACGCTCGA
CCTCGGCGCGCTGCCCGCCGACGTCCGCGTCCCGGAGACCGCCCCGGCGGTCGAGGCGCTGCTGGACGAGGCGGCGCAGC
GGAGCCCCGACCTGGCCCGCGCGCGCGCCCAGGCCGGTGCGGCCGCCGCCGGCGCGCGGGCCGCCGAGCGCGCCTGGCTC
CCGCTGCTCTCGCTCGGCGCGACCGCCAGCCGCTCCTGGTACCTCGACCCGTCCGGCGTGCCGCCCTCCACCGCCTGGAC
GGTGGGGCTCTCGCTGCGCATCCCGCTGCTCGAGGGGCTCCTCCGGCCGGCGTACGACGCGCTCGCCGCCCGCGCCGACG
CCGACGCCGCCGAGGCGCGCGCCGCCGCGACCGCGCAGGCGGTGGCCCTCCAGGTCTGGACCGGCTACCAGGCGTTCCGC
ACCGCCGGCCTCCGCGTCGAGACCGCGCGCGACCTGCTCGCCTCGGCCCAGGCCTCGAGCAACGTCGCCGCCGGGCGGTA
CCGCGAGGGCGTCGGCTCCATCCTCGATCTCCTCACCGCGCAGGCCGCGCTGGAGGGCGCCCGGGCCGAGGAGGTGCGCG
CCCGCGCCGACTACCTGGTGGCACTGGCCCAGCTCGCCCGCGCCACCGGCCGCCTCGCGCCGCCGGCCCAGGCCGCCGCC
GCGCCGACGCCCGCGCCAGAAGGGAACCCATGA

Upstream 100 bases:

>100_bases
GCGGATGGGTCGCGCGCGCGACTTCCTTCCGGAAATCCCGCGCGCCCCGGGCCACTCCGCCGTTGACGCGCGGGCCGGCC
TCCTTCAAATAGGGCAGAGC

Downstream 100 bases:

>100_bases
CCGCCCCCCGCGCCGCGCCGCTCGCGCTCACCCTCCTCGCGCTCGCCGCCGCCTGCGGGCGGGGCGACGCCGGACCGAAG
GGCCCGCGCCCGGTGGCGGT

Product: outer membrane efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 489

Protein sequence:

>490_residues
MAAPRARTAAVLALLLPASGCATLAPSGFVDGRTAPPPEVARRAATEPAPARAAAGPAPSPPSPAPAAPRSIPELVARAL
EVDPATRAAWHDARAAAAAAGGERTAYLPSVSVGAGLQRAETARTLTRAGTTATTAGPSGELTWILLDLGARAARVEQAD
QLLLASRLAEHAAVADLVLRVQETAYQYLGSRALVEAEAAAVKQAEESLAAAEGRRGAGVATVADVLQARTARSQARLRL
QQLEGQALTVGGALATLAGLPPTATLDLGALPADVRVPETAPAVEALLDEAAQRSPDLARARAQAGAAAAGARAAERAWL
PLLSLGATASRSWYLDPSGVPPSTAWTVGLSLRIPLLEGLLRPAYDALAARADADAAEARAAATAQAVALQVWTGYQAFR
TAGLRVETARDLLASAQASSNVAAGRYREGVGSILDLLTAQAALEGARAEEVRARADYLVALAQLARATGRLAPPAQAAA
APTPAPEGNP

Sequences:

>Translated_490_residues
MAAPRARTAAVLALLLPASGCATLAPSGFVDGRTAPPPEVARRAATEPAPARAAAGPAPSPPSPAPAAPRSIPELVARAL
EVDPATRAAWHDARAAAAAAGGERTAYLPSVSVGAGLQRAETARTLTRAGTTATTAGPSGELTWILLDLGARAARVEQAD
QLLLASRLAEHAAVADLVLRVQETAYQYLGSRALVEAEAAAVKQAEESLAAAEGRRGAGVATVADVLQARTARSQARLRL
QQLEGQALTVGGALATLAGLPPTATLDLGALPADVRVPETAPAVEALLDEAAQRSPDLARARAQAGAAAAGARAAERAWL
PLLSLGATASRSWYLDPSGVPPSTAWTVGLSLRIPLLEGLLRPAYDALAARADADAAEARAAATAQAVALQVWTGYQAFR
TAGLRVETARDLLASAQASSNVAAGRYREGVGSILDLLTAQAALEGARAEEVRARADYLVALAQLARATGRLAPPAQAAA
APTPAPEGNP
>Mature_489_residues
AAPRARTAAVLALLLPASGCATLAPSGFVDGRTAPPPEVARRAATEPAPARAAAGPAPSPPSPAPAAPRSIPELVARALE
VDPATRAAWHDARAAAAAAGGERTAYLPSVSVGAGLQRAETARTLTRAGTTATTAGPSGELTWILLDLGARAARVEQADQ
LLLASRLAEHAAVADLVLRVQETAYQYLGSRALVEAEAAAVKQAEESLAAAEGRRGAGVATVADVLQARTARSQARLRLQ
QLEGQALTVGGALATLAGLPPTATLDLGALPADVRVPETAPAVEALLDEAAQRSPDLARARAQAGAAAAGARAAERAWLP
LLSLGATASRSWYLDPSGVPPSTAWTVGLSLRIPLLEGLLRPAYDALAARADADAAEARAAATAQAVALQVWTGYQAFRT
AGLRVETARDLLASAQASSNVAAGRYREGVGSILDLLTAQAALEGARAEEVRARADYLVALAQLARATGRLAPPAQAAAA
PTPAPEGNP

Specific function: The outer membrane component of an antibiotic efflux pump. Confers resistance to numerous structurally unrelated antibiotics such as carbenicillin, chloramphenicol, erythromycin, novobiocin, streptomycin and tetracycline. Is not involved in organic solven

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 49617; Mature: 49486

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.2 %Met     (Translated Protein)
0.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAPRARTAAVLALLLPASGCATLAPSGFVDGRTAPPPEVARRAATEPAPARAAAGPAPS
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCC
PPSPAPAAPRSIPELVARALEVDPATRAAWHDARAAAAAAGGERTAYLPSVSVGAGLQRA
CCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCHHCCCHHHH
ETARTLTRAGTTATTAGPSGELTWILLDLGARAARVEQADQLLLASRLAEHAAVADLVLR
HHHHHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQETAYQYLGSRALVEAEAAAVKQAEESLAAAEGRRGAGVATVADVLQARTARSQARLRL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QQLEGQALTVGGALATLAGLPPTATLDLGALPADVRVPETAPAVEALLDEAAQRSPDLAR
HHHCCCEEEECHHHHHHHCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHH
ARAQAGAAAAGARAAERAWLPLLSLGATASRSWYLDPSGVPPSTAWTVGLSLRIPLLEGL
HHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCEEEEEEEEECHHHHHH
LRPAYDALAARADADAAEARAAATAQAVALQVWTGYQAFRTAGLRVETARDLLASAQASS
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHHHCC
NVAAGRYREGVGSILDLLTAQAALEGARAEEVRARADYLVALAQLARATGRLAPPAQAAA
CCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCC
APTPAPEGNP
CCCCCCCCCC
>Mature Secondary Structure 
AAPRARTAAVLALLLPASGCATLAPSGFVDGRTAPPPEVARRAATEPAPARAAAGPAPS
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCC
PPSPAPAAPRSIPELVARALEVDPATRAAWHDARAAAAAAGGERTAYLPSVSVGAGLQRA
CCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCHHCCCHHHH
ETARTLTRAGTTATTAGPSGELTWILLDLGARAARVEQADQLLLASRLAEHAAVADLVLR
HHHHHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQETAYQYLGSRALVEAEAAAVKQAEESLAAAEGRRGAGVATVADVLQARTARSQARLRL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QQLEGQALTVGGALATLAGLPPTATLDLGALPADVRVPETAPAVEALLDEAAQRSPDLAR
HHHCCCEEEECHHHHHHHCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHH
ARAQAGAAAAGARAAERAWLPLLSLGATASRSWYLDPSGVPPSTAWTVGLSLRIPLLEGL
HHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCEEEEEEEEECHHHHHH
LRPAYDALAARADADAAEARAAATAQAVALQVWTGYQAFRTAGLRVETARDLLASAQASS
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHHHCC
NVAAGRYREGVGSILDLLTAQAALEGARAEEVRARADYLVALAQLARATGRLAPPAQAAA
CCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCC
APTPAPEGNP
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11160799 [H]