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The map label for this gene is tag [H]

Identifier: 220916899

GI number: 220916899

Start: 2004839

End: 2005570

Strand: Reverse

Name: tag [H]

Synonym: A2cp1_1795

Alternate gene names: 220916899

Gene position: 2005570-2004839 (Counterclockwise)

Preceding gene: 220916904

Following gene: 220916896

Centisome position: 39.88

GC content: 75.27

Gene sequence:

>732_bases
ATGCCCCAGCACGCCCACGCGCTCGACGACGGCCTCGGCACGGGCCCCGACGGCCGGGCCCGCTGCGCCTGGGGGCTCTC
GGCCGCGGACTACGTCCGGTACCACGACGAGGAGTGGGGGCTCCCCGTCGCGGACGATCGCCGGCTGTTCGAGAAGCTGT
GCCTGGAAGGCTTCCAGTCCGGCCTGTCGTGGCTCACCATCCTGCGCAAGCGCGAGGCGTTCCGGACCGCGTTCGCCGGC
TTCGACTTCGAGAAGGTGGCCCGCTTCGGCGCCCGCGACGTGGCGCGCCTGCTCGGGGACGCCGGCATCGTGCGCCACCG
CGGCAAGATCGAGGCGACGCTCAACAACGCGCGGCGCGCCTGCGAGCTCGCCGCCGAGGCCGGATCTCTCGCGGCCTACT
TCTGGCAATTCGAGCCGCCGAAGGCCTCGCGGCCGGAGCGGGTCACCTGGGCGGCGCTCCGGGCGCAGCCGGTCACCACG
GAATCGAAAGCGCTCTCGCGCGACCTGAAGCGGCGCGGCTGGGCGTTCGTCGGGCCGACCACCTGCTACGCGTTCATGCA
GGCCATGGGGCTCGTGAACGACCACGTGGAGGGCTGCGCCGTGCGCGGCCGCGTCGAGCGGGCGCGGCGCGGGTTCGAGC
GGCCGGTCGTCGTCGACGGGGCGTCAGCGGAGCCCGAGCCGGCGCCAGCGTCCCGCGCACGAGCCCGGGCCGTCGCGCGG
GGGCGCCGCTAG

Upstream 100 bases:

>100_bases
CGAGCCACCATCGGGTGCCTGCCCGGCGCCTTGACGCCGCCCCCGCCGGCCGGCAGGTTCCGCGCACACGGCGCCGGCGC
ACCGGCGCGGGAGGAACCCG

Downstream 100 bases:

>100_bases
CCCGGGTCGCCGCCCGGGCGCTGCCGCTATCGAGGATCCTGGGGGGGCGCGGGCGGACGCACGAGCCGCTGGAAGAGCCG
CTCGAGCGCGCGGTCCGGGT

Product: DNA-3-methyladenine glycosylase I

Products: NA

Alternate protein names: 3-methyladenine-DNA glycosylase I, constitutive; TAG I; DNA-3-methyladenine glycosidase I; DNA-3-methyladenine glycosylase I [H]

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MPQHAHALDDGLGTGPDGRARCAWGLSAADYVRYHDEEWGLPVADDRRLFEKLCLEGFQSGLSWLTILRKREAFRTAFAG
FDFEKVARFGARDVARLLGDAGIVRHRGKIEATLNNARRACELAAEAGSLAAYFWQFEPPKASRPERVTWAALRAQPVTT
ESKALSRDLKRRGWAFVGPTTCYAFMQAMGLVNDHVEGCAVRGRVERARRGFERPVVVDGASAEPEPAPASRARARAVAR
GRR

Sequences:

>Translated_243_residues
MPQHAHALDDGLGTGPDGRARCAWGLSAADYVRYHDEEWGLPVADDRRLFEKLCLEGFQSGLSWLTILRKREAFRTAFAG
FDFEKVARFGARDVARLLGDAGIVRHRGKIEATLNNARRACELAAEAGSLAAYFWQFEPPKASRPERVTWAALRAQPVTT
ESKALSRDLKRRGWAFVGPTTCYAFMQAMGLVNDHVEGCAVRGRVERARRGFERPVVVDGASAEPEPAPASRARARAVAR
GRR
>Mature_242_residues
PQHAHALDDGLGTGPDGRARCAWGLSAADYVRYHDEEWGLPVADDRRLFEKLCLEGFQSGLSWLTILRKREAFRTAFAGF
DFEKVARFGARDVARLLGDAGIVRHRGKIEATLNNARRACELAAEAGSLAAYFWQFEPPKASRPERVTWAALRAQPVTTE
SKALSRDLKRRGWAFVGPTTCYAFMQAMGLVNDHVEGCAVRGRVERARRGFERPVVVDGASAEPEPAPASRARARAVARG
RR

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG2818

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789971, Length=181, Percent_Identity=48.0662983425414, Blast_Score=180, Evalue=7e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005019
- InterPro:   IPR011257
- InterPro:   IPR004597 [H]

Pfam domain/function: PF03352 Adenine_glyco [H]

EC number: =3.2.2.20 [H]

Molecular weight: Translated: 26908; Mature: 26777

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQHAHALDDGLGTGPDGRARCAWGLSAADYVRYHDEEWGLPVADDRRLFEKLCLEGFQS
CCCHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
GLSWLTILRKREAFRTAFAGFDFEKVARFGARDVARLLGDAGIVRHRGKIEATLNNARRA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
CELAAEAGSLAAYFWQFEPPKASRPERVTWAALRAQPVTTESKALSRDLKRRGWAFVGPT
HHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCEEECHH
TCYAFMQAMGLVNDHVEGCAVRGRVERARRGFERPVVVDGASAEPEPAPASRARARAVAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHC
GRR
CCC
>Mature Secondary Structure 
PQHAHALDDGLGTGPDGRARCAWGLSAADYVRYHDEEWGLPVADDRRLFEKLCLEGFQS
CCHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
GLSWLTILRKREAFRTAFAGFDFEKVARFGARDVARLLGDAGIVRHRGKIEATLNNARRA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
CELAAEAGSLAAYFWQFEPPKASRPERVTWAALRAQPVTTESKALSRDLKRRGWAFVGPT
HHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCEEECHH
TCYAFMQAMGLVNDHVEGCAVRGRVERARRGFERPVVVDGASAEPEPAPASRARARAVAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHC
GRR
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3536912; 3520491; 8041620; 9278503 [H]