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The map label for this gene is mprF [H]

Identifier: 220916798

GI number: 220916798

Start: 1885309

End: 1887843

Strand: Reverse

Name: mprF [H]

Synonym: A2cp1_1693

Alternate gene names: 220916798

Gene position: 1887843-1885309 (Counterclockwise)

Preceding gene: 220916799

Following gene: 220916797

Centisome position: 37.54

GC content: 75.58

Gene sequence:

>2535_bases
GTGACATGGCTCCGCCGCGCCGCGCTGGTGCTCCTCCCCGTCGCCCTGCTCGGCGCGGCCGCCTGGACGCTCCACGTGGA
GCTGCGCGGCCTCCACCTGCACCAGGTGGAGCGCGAGCTGTCGGCGCTGCCGGCGGCCCTGCTCGCGCTCGCCGCCGGGC
TCACCGCGCTCGACTACCTGCTGCTCTCCGCCTACGACGTGCTGGCGCTCCGCTACGCCGGGCGCCGCCTCCCGTACTCG
CGGGTGGTCTTCACCTCGTTCGTCTCCTACGCGTTCGGGAACAACGTCGGGTTCGCGCTGCTGTCCTCCGGCTCGGTGCG
GTTCCGCCTCTACTCGCAGTGGGGCCTCTCCGCGCTCGAGATCACGCGGGTGGTCGCGTTCACCGCCGCGCAGCTCTGGG
CCGGCCTCCTGCCCATCGCCGGGGTGGCGCTGCTGTCCGGGCTGCCGGTGCCGCTCCCGGGCTGGGCGGCCCGGGCGCTG
GGCGCCGCCGCGCTGGCGGTGACCGCGGCCTACGTGGTCGCCGCCGCCCGCGGCACGACGCTCTCGGTGAAGGGCGTCCG
CTTCTCGCTGCCCTCGCTGCCGCTGACGCTCGCGCAGATCGTCGTGTCCGCCGCAGACTGGGCGCTGGCGGCGCTGGTGC
TCCACGTGCTGCTCCCGCCCGCCTCGCCCCTCGGCTTCGTGCAGCTGCTCGGGCTGTTCGTGGCCGCGCAGGTGGTGGGC
CTGGCCTCGCAGGTGCCGGGCGGCCTGGGCGTGTTCGAGTCGATCGTGCTCGCGGCGCTGACGCCCGCGGTGCCGGCGCC
GGCGGTGGTGTCGAGCCTGGTGGCGTTCCGGCTCGTCTACTACGTGGCCCCGTTCCTGGCCGCGTTCGCCCTGCTCGCGA
CGCACGAGCTGCTGCTGCGGCGCGCCTGGCTGGGGCGGGTCCTGCGCGGCGCGCACGCCTCCTTCGCCCCGGTGGTGCCG
TGGCTGGCCGGCGGCGCCGCGCTGCTCGCCGGCGCGGTGCTGCTCGTCTCGGGCGCCACGCCGGCGGAGGCCGAGCGGCT
CCACCTGCTGCGCCGCGCCGTGCCGCTGCCGGTGCTGGAGGCGTCGCACCTGGTCGGGAGCCTGGTCGGGACGGCGCTGC
TCCTCCTCGCCCGCGCGCTGGTCCGCCGCATCGACGCGGCCTGGGCGGTCGCCATCGGGCTGCTCGCGGCGGGCGCGGTG
GCCTCGCTCGCGAAGGGGCTCGACTGGGAGGAGGCGACGCTGCTCGTCGCGCTGCTCGCGGCCATCGCGCCGTTCCACCG
CCAGTTCTACCGGCGCAGCTCGATGCTCGAGGGCGTCCCCTCCGCCGGCTGGGCGCTCGGGGTGGCGCTGCTGGTGGCCG
GCTCGATCGTGATCGGCGTGCTCTCGTACCGGCACGTGGAGTGGTCGCGGGACCTGTGGTTCACGTTCGCGTTCCACGGG
GACGCGCCGCGGTTCCTGCGCGCCTCGGTGGCCGGCGTGTCGCTCCTGGTGCTGTTCGGGGTGGCGACGCTGCTCCGGCC
TGCGCCGCCCGAGCCCCCGCGCACGGGCCAGGCGGAGCTGGACCGGGTGCGCCCGCTGGTGGACCGCGCGCCGGAGTCCT
ACGCGCACCTCGCGCTCACCGGCGACAAGTGCCTGCTGTTCGCGGAGGCCGACGCCGCGTTCCTGATGTACGCGGTCGAG
GGCCGGAGCTGGATCGCCATGGGCGATCCGGTCGGCCCGGACCCGGCCGCGACCGAGCTGGCCTGGCGCTTCCGGGAGCT
GTCGGACCGGCACGACGGCTGGGCCTGCTTCTACCAGGTCGGGCCGGCCGCGCTGCCGCGCTACCTCGACCTGGGCCTCT
CCCTGCTGAAGCTGGGCGAGGAGGCGGTGGTGCCGCTGGACGGGTTCTCGCTCGACGGGAGCGCCCGCCGGGCGCTGCGC
CAGGCGCACGCCCGTGCGGAGCGCGACGGCCTCTCCTTCGAGGTCGCGCCCGCCCCGGCCGTGCCCGGGCTCCTCCCGGA
TCTCGCCGCCGTCTCGGACGCGTGGCTGATCGAGAAGGGCGTGCGCGAGAAGGGCTTCTCCCTCGGGTCGTTCGACGCGC
GCTACCTGGCGGAGGGGCCGGTCGCGCTGGTGCGCCTCGACGGCAAGATCGTGGGCTTCGCGAACGTGTGGGCCAGCGCG
GCCCGCGTGGAGCTGTCGGTGGACCTCATGCGCTACCACCCCTCCGCGCCGCGCTCGACCATGGACTACCTGTTCACCTC
GCTCATGCTCTGGGGAAGGGCCGAGGGCTACCGCGCGTTCAACCTCGGCATGGCCCCGTTCTCCGGGTTCGAGCCGCGCC
AGCTCGCGCCCCTGTGGACGCGGATGGGCGCCCGGCTCTACCGGCACGGCGAGAACTTCTACAACTTCCAGGGGCTCCGC
GCGTACAAGGAGAAGTTCGCGCCGGAGTGGCGGCCGCGCTGGCTGGCCGCGCCCGGCGGGCTCCGCCTCCCCGCCATCCT
CGCGAACCTGGCCGCGCTCGTCTCGCGCGGCCTGAAGGGCGTGGTGACCAAATGA

Upstream 100 bases:

>100_bases
GCCCGGGGTCGACGGTGCGTGAACCTCCGGCAACGGTGCCGCGCCGCACGCCCCGTCGCGGAAGTGGACCGCGGCCCGGG
TTCGGGACTCTCATTCGAGG

Downstream 100 bases:

>100_bases
TCCCTGCCGCGCTGGCGCTGGCCCTCGCCGCCGTCCCCGCCACCCTCGACGTCCCCGGCCTCGGGGCCGTGCCCGTCTCC
GCGCCGCCCGGGGCGCCGCA

Product: hypothetical protein

Products: NA

Alternate protein names: Lysylphosphatidylglycerol synthase; LPG synthase [H]

Number of amino acids: Translated: 844; Mature: 843

Protein sequence:

>844_residues
MTWLRRAALVLLPVALLGAAAWTLHVELRGLHLHQVERELSALPAALLALAAGLTALDYLLLSAYDVLALRYAGRRLPYS
RVVFTSFVSYAFGNNVGFALLSSGSVRFRLYSQWGLSALEITRVVAFTAAQLWAGLLPIAGVALLSGLPVPLPGWAARAL
GAAALAVTAAYVVAAARGTTLSVKGVRFSLPSLPLTLAQIVVSAADWALAALVLHVLLPPASPLGFVQLLGLFVAAQVVG
LASQVPGGLGVFESIVLAALTPAVPAPAVVSSLVAFRLVYYVAPFLAAFALLATHELLLRRAWLGRVLRGAHASFAPVVP
WLAGGAALLAGAVLLVSGATPAEAERLHLLRRAVPLPVLEASHLVGSLVGTALLLLARALVRRIDAAWAVAIGLLAAGAV
ASLAKGLDWEEATLLVALLAAIAPFHRQFYRRSSMLEGVPSAGWALGVALLVAGSIVIGVLSYRHVEWSRDLWFTFAFHG
DAPRFLRASVAGVSLLVLFGVATLLRPAPPEPPRTGQAELDRVRPLVDRAPESYAHLALTGDKCLLFAEADAAFLMYAVE
GRSWIAMGDPVGPDPAATELAWRFRELSDRHDGWACFYQVGPAALPRYLDLGLSLLKLGEEAVVPLDGFSLDGSARRALR
QAHARAERDGLSFEVAPAPAVPGLLPDLAAVSDAWLIEKGVREKGFSLGSFDARYLAEGPVALVRLDGKIVGFANVWASA
ARVELSVDLMRYHPSAPRSTMDYLFTSLMLWGRAEGYRAFNLGMAPFSGFEPRQLAPLWTRMGARLYRHGENFYNFQGLR
AYKEKFAPEWRPRWLAAPGGLRLPAILANLAALVSRGLKGVVTK

Sequences:

>Translated_844_residues
MTWLRRAALVLLPVALLGAAAWTLHVELRGLHLHQVERELSALPAALLALAAGLTALDYLLLSAYDVLALRYAGRRLPYS
RVVFTSFVSYAFGNNVGFALLSSGSVRFRLYSQWGLSALEITRVVAFTAAQLWAGLLPIAGVALLSGLPVPLPGWAARAL
GAAALAVTAAYVVAAARGTTLSVKGVRFSLPSLPLTLAQIVVSAADWALAALVLHVLLPPASPLGFVQLLGLFVAAQVVG
LASQVPGGLGVFESIVLAALTPAVPAPAVVSSLVAFRLVYYVAPFLAAFALLATHELLLRRAWLGRVLRGAHASFAPVVP
WLAGGAALLAGAVLLVSGATPAEAERLHLLRRAVPLPVLEASHLVGSLVGTALLLLARALVRRIDAAWAVAIGLLAAGAV
ASLAKGLDWEEATLLVALLAAIAPFHRQFYRRSSMLEGVPSAGWALGVALLVAGSIVIGVLSYRHVEWSRDLWFTFAFHG
DAPRFLRASVAGVSLLVLFGVATLLRPAPPEPPRTGQAELDRVRPLVDRAPESYAHLALTGDKCLLFAEADAAFLMYAVE
GRSWIAMGDPVGPDPAATELAWRFRELSDRHDGWACFYQVGPAALPRYLDLGLSLLKLGEEAVVPLDGFSLDGSARRALR
QAHARAERDGLSFEVAPAPAVPGLLPDLAAVSDAWLIEKGVREKGFSLGSFDARYLAEGPVALVRLDGKIVGFANVWASA
ARVELSVDLMRYHPSAPRSTMDYLFTSLMLWGRAEGYRAFNLGMAPFSGFEPRQLAPLWTRMGARLYRHGENFYNFQGLR
AYKEKFAPEWRPRWLAAPGGLRLPAILANLAALVSRGLKGVVTK
>Mature_843_residues
TWLRRAALVLLPVALLGAAAWTLHVELRGLHLHQVERELSALPAALLALAAGLTALDYLLLSAYDVLALRYAGRRLPYSR
VVFTSFVSYAFGNNVGFALLSSGSVRFRLYSQWGLSALEITRVVAFTAAQLWAGLLPIAGVALLSGLPVPLPGWAARALG
AAALAVTAAYVVAAARGTTLSVKGVRFSLPSLPLTLAQIVVSAADWALAALVLHVLLPPASPLGFVQLLGLFVAAQVVGL
ASQVPGGLGVFESIVLAALTPAVPAPAVVSSLVAFRLVYYVAPFLAAFALLATHELLLRRAWLGRVLRGAHASFAPVVPW
LAGGAALLAGAVLLVSGATPAEAERLHLLRRAVPLPVLEASHLVGSLVGTALLLLARALVRRIDAAWAVAIGLLAAGAVA
SLAKGLDWEEATLLVALLAAIAPFHRQFYRRSSMLEGVPSAGWALGVALLVAGSIVIGVLSYRHVEWSRDLWFTFAFHGD
APRFLRASVAGVSLLVLFGVATLLRPAPPEPPRTGQAELDRVRPLVDRAPESYAHLALTGDKCLLFAEADAAFLMYAVEG
RSWIAMGDPVGPDPAATELAWRFRELSDRHDGWACFYQVGPAALPRYLDLGLSLLKLGEEAVVPLDGFSLDGSARRALRQ
AHARAERDGLSFEVAPAPAVPGLLPDLAAVSDAWLIEKGVREKGFSLGSFDARYLAEGPVALVRLDGKIVGFANVWASAA
RVELSVDLMRYHPSAPRSTMDYLFTSLMLWGRAEGYRAFNLGMAPFSGFEPRQLAPLWTRMGARLYRHGENFYNFQGLRA
YKEKFAPEWRPRWLAAPGGLRLPAILANLAALVSRGLKGVVTK

Specific function: Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contribu

COG id: COG2898

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LPG synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787006, Length=294, Percent_Identity=30.2721088435374, Blast_Score=120, Evalue=5e-28,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016181
- InterPro:   IPR022791 [H]

Pfam domain/function: PF03706 UPF0104 [H]

EC number: =2.3.2.3 [H]

Molecular weight: Translated: 90021; Mature: 89890

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTWLRRAALVLLPVALLGAAAWTLHVELRGLHLHQVERELSALPAALLALAAGLTALDYL
CCHHHHHHHHHHHHHHHHHHHEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLSAYDVLALRYAGRRLPYSRVVFTSFVSYAFGNNVGFALLSSGSVRFRLYSQWGLSALE
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEEHHHCCHHHH
ITRVVAFTAAQLWAGLLPIAGVALLSGLPVPLPGWAARALGAAALAVTAAYVVAAARGTT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCE
LSVKGVRFSLPSLPLTLAQIVVSAADWALAALVLHVLLPPASPLGFVQLLGLFVAAQVVG
EEECCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
LASQVPGGLGVFESIVLAALTPAVPAPAVVSSLVAFRLVYYVAPFLAAFALLATHELLLR
HHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAWLGRVLRGAHASFAPVVPWLAGGAALLAGAVLLVSGATPAEAERLHLLRRAVPLPVLE
HHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHH
ASHLVGSLVGTALLLLARALVRRIDAAWAVAIGLLAAGAVASLAKGLDWEEATLLVALLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AIAPFHRQFYRRSSMLEGVPSAGWALGVALLVAGSIVIGVLSYRHVEWSRDLWFTFAFHG
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEC
DAPRFLRASVAGVSLLVLFGVATLLRPAPPEPPRTGQAELDRVRPLVDRAPESYAHLALT
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEE
GDKCLLFAEADAAFLMYAVEGRSWIAMGDPVGPDPAATELAWRFRELSDRHDGWACFYQV
CCEEEEEEECCCEEEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEC
GPAALPRYLDLGLSLLKLGEEAVVPLDGFSLDGSARRALRQAHARAERDGLSFEVAPAPA
CHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCC
VPGLLPDLAAVSDAWLIEKGVREKGFSLGSFDARYLAEGPVALVRLDGKIVGFANVWASA
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCEEEEEECCCEEEHHHHHHHH
ARVELSVDLMRYHPSAPRSTMDYLFTSLMLWGRAEGYRAFNLGMAPFSGFEPRQLAPLWT
HHHEEEEHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHH
RMGARLYRHGENFYNFQGLRAYKEKFAPEWRPRWLAAPGGLRLPAILANLAALVSRGLKG
HHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHHCCCCC
VVTK
CCCC
>Mature Secondary Structure 
TWLRRAALVLLPVALLGAAAWTLHVELRGLHLHQVERELSALPAALLALAAGLTALDYL
CHHHHHHHHHHHHHHHHHHHEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLSAYDVLALRYAGRRLPYSRVVFTSFVSYAFGNNVGFALLSSGSVRFRLYSQWGLSALE
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEEHHHCCHHHH
ITRVVAFTAAQLWAGLLPIAGVALLSGLPVPLPGWAARALGAAALAVTAAYVVAAARGTT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCE
LSVKGVRFSLPSLPLTLAQIVVSAADWALAALVLHVLLPPASPLGFVQLLGLFVAAQVVG
EEECCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
LASQVPGGLGVFESIVLAALTPAVPAPAVVSSLVAFRLVYYVAPFLAAFALLATHELLLR
HHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAWLGRVLRGAHASFAPVVPWLAGGAALLAGAVLLVSGATPAEAERLHLLRRAVPLPVLE
HHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHH
ASHLVGSLVGTALLLLARALVRRIDAAWAVAIGLLAAGAVASLAKGLDWEEATLLVALLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AIAPFHRQFYRRSSMLEGVPSAGWALGVALLVAGSIVIGVLSYRHVEWSRDLWFTFAFHG
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEC
DAPRFLRASVAGVSLLVLFGVATLLRPAPPEPPRTGQAELDRVRPLVDRAPESYAHLALT
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEE
GDKCLLFAEADAAFLMYAVEGRSWIAMGDPVGPDPAATELAWRFRELSDRHDGWACFYQV
CCEEEEEEECCCEEEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEC
GPAALPRYLDLGLSLLKLGEEAVVPLDGFSLDGSARRALRQAHARAERDGLSFEVAPAPA
CHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCC
VPGLLPDLAAVSDAWLIEKGVREKGFSLGSFDARYLAEGPVALVRLDGKIVGFANVWASA
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCEEEEEECCCEEEHHHHHHHH
ARVELSVDLMRYHPSAPRSTMDYLFTSLMLWGRAEGYRAFNLGMAPFSGFEPRQLAPLWT
HHHEEEEHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHH
RMGARLYRHGENFYNFQGLRAYKEKFAPEWRPRWLAAPGGLRLPAILANLAALVSRGLKG
HHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHHCCCCC
VVTK
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]