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The map label for this gene is 220916759

Identifier: 220916759

GI number: 220916759

Start: 1846704

End: 1847855

Strand: Reverse

Name: 220916759

Synonym: A2cp1_1654

Alternate gene names: NA

Gene position: 1847855-1846704 (Counterclockwise)

Preceding gene: 220916768

Following gene: 220916758

Centisome position: 36.74

GC content: 73.26

Gene sequence:

>1152_bases
GTGGAGCCCTTCGCCATCGACGTTCCCGAGGCCGTCCTGCACGACTTGCGCGAGAGGCTCCGCGCGACGCGCTGGCCCGA
CGCCGTCGAGGGCGCCGGCTGGGACTACGGCGCGGACCTCGCGTACATGCAGGAGCTGGTGGCGTACTGGGTCGACCGGT
TCGACTGGCGCGCGCAGGAGCGCCGCCTGAACCAGCTCCCCCAGTTCCGCGCGCGGGTCGACGGCCTCGGCATCCACTTC
GTGCACGTCCGCGGGCGCGGACCGGCCCCCATCCCGCTCGTGCTCACACATGGCTGGCCGAGCTCGTTCATCGAGCTCGA
GGCCGTCGCCGGCCCGCTCGCTGACCCCGCCAGCCACGGCGGCGATGCGCGCGACGCGTTCGACGTGGTGATCCCCTCCA
TGCCCGGCTTCGGTTTCTCCGATCGGCCCACGGCCCGGGGGTTCGTCCGGGTGGACCGGCTCTGGCGCAAGCTGATGACC
CAGGTCCTCGGCTACCCCTGGTTCGTGGCGCACGGGACCGACGTCGGCGCGCGCGTGACGAGCGCGCTCGGGCGGTTCCA
GGCGGACGTGGTGCGCGGGATCCACCTCGGCTCCGTGGATCTCGAGTGGCCCGACCCGCCGCCCGACGCGGCGAGCATGA
CCGCCGCGGAGCGGGACTACGTGGCGCGCTGCGCGCGCTGGGAGAAGGAGCAGGGGGCGTACGGCGAGCTCCAGGCCACC
ACGCCGCAGACCGCCGCGTACGGCCTCAACGACTCGCCCGCCGCGCTCGCGGCCTGGATCGTGGAGAAGTACCGCGCCTG
GAGCGACTGCGGCGGCGAGGTGGAGCGCCGGTTCTCCAAGGACACGCTCCTCACCAACGTCGTCGTGTACTGGGCGACGC
AGACGATCAACTCCTCGATGCGCCGCTACTACGAGGTGCGCCACGATCCGCAGCCGCCGCTGCGGCCCGGGGAGCGCATC
GAGGCGCCCGCTTCCATCGCCATGTTCCCCGGCGAGCGCGACCTCCTCGTCCCGCGCGAATGGGCGGAGCGCTGCTACCA
CGTCCGCCGCTGGACCAACATGCCGCGCGGCGGCCACTTCCCCGCGCTGGAGGAGCCCGAGCTGCTGGTGCAGGACCTCC
GGGAGAGCTTCCGGCCGTTGCGCGGCAGCTGA

Upstream 100 bases:

>100_bases
CGAACCCGAACCGGTAGCATGCGGCAGGGCGGCGCCGGCACTACCAGAGGGGCCTCGATGCGCTGGCGGCGCGAAGCCGC
GGGCGCAGCCTGGAGGCCGC

Downstream 100 bases:

>100_bases
CGCGCGCCACGGCGATCGCCGACCCGCCTCGGCTGTCAGACGGAGCCTGTACATCCGTTCCGTCTCGCACGCGAGGCCGG
CGGCCATGCGACTCCTCTTC

Product: Epoxide hydrolase domain-containing protein

Products: NA

Alternate protein names: Epoxide hydratase [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MEPFAIDVPEAVLHDLRERLRATRWPDAVEGAGWDYGADLAYMQELVAYWVDRFDWRAQERRLNQLPQFRARVDGLGIHF
VHVRGRGPAPIPLVLTHGWPSSFIELEAVAGPLADPASHGGDARDAFDVVIPSMPGFGFSDRPTARGFVRVDRLWRKLMT
QVLGYPWFVAHGTDVGARVTSALGRFQADVVRGIHLGSVDLEWPDPPPDAASMTAAERDYVARCARWEKEQGAYGELQAT
TPQTAAYGLNDSPAALAAWIVEKYRAWSDCGGEVERRFSKDTLLTNVVVYWATQTINSSMRRYYEVRHDPQPPLRPGERI
EAPASIAMFPGERDLLVPREWAERCYHVRRWTNMPRGGHFPALEEPELLVQDLRESFRPLRGS

Sequences:

>Translated_383_residues
MEPFAIDVPEAVLHDLRERLRATRWPDAVEGAGWDYGADLAYMQELVAYWVDRFDWRAQERRLNQLPQFRARVDGLGIHF
VHVRGRGPAPIPLVLTHGWPSSFIELEAVAGPLADPASHGGDARDAFDVVIPSMPGFGFSDRPTARGFVRVDRLWRKLMT
QVLGYPWFVAHGTDVGARVTSALGRFQADVVRGIHLGSVDLEWPDPPPDAASMTAAERDYVARCARWEKEQGAYGELQAT
TPQTAAYGLNDSPAALAAWIVEKYRAWSDCGGEVERRFSKDTLLTNVVVYWATQTINSSMRRYYEVRHDPQPPLRPGERI
EAPASIAMFPGERDLLVPREWAERCYHVRRWTNMPRGGHFPALEEPELLVQDLRESFRPLRGS
>Mature_383_residues
MEPFAIDVPEAVLHDLRERLRATRWPDAVEGAGWDYGADLAYMQELVAYWVDRFDWRAQERRLNQLPQFRARVDGLGIHF
VHVRGRGPAPIPLVLTHGWPSSFIELEAVAGPLADPASHGGDARDAFDVVIPSMPGFGFSDRPTARGFVRVDRLWRKLMT
QVLGYPWFVAHGTDVGARVTSALGRFQADVVRGIHLGSVDLEWPDPPPDAASMTAAERDYVARCARWEKEQGAYGELQAT
TPQTAAYGLNDSPAALAAWIVEKYRAWSDCGGEVERRFSKDTLLTNVVVYWATQTINSSMRRYYEVRHDPQPPLRPGERI
EAPASIAMFPGERDLLVPREWAERCYHVRRWTNMPRGGHFPALEEPELLVQDLRESFRPLRGS

Specific function: Unknown

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

Organism=Homo sapiens, GI4503583, Length=407, Percent_Identity=33.9066339066339, Blast_Score=240, Evalue=2e-63,
Organism=Homo sapiens, GI209862837, Length=407, Percent_Identity=33.9066339066339, Blast_Score=240, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI17564944, Length=407, Percent_Identity=32.6781326781327, Blast_Score=219, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI193207462, Length=412, Percent_Identity=25.2427184466019, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI20130139, Length=400, Percent_Identity=29.25, Blast_Score=165, Evalue=6e-41,
Organism=Drosophila melanogaster, GI24655327, Length=404, Percent_Identity=29.9504950495049, Blast_Score=164, Evalue=9e-41,
Organism=Drosophila melanogaster, GI19922580, Length=399, Percent_Identity=27.5689223057644, Blast_Score=147, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =3.3.2.10 [H]

Molecular weight: Translated: 43296; Mature: 43296

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPFAIDVPEAVLHDLRERLRATRWPDAVEGAGWDYGADLAYMQELVAYWVDRFDWRAQE
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RRLNQLPQFRARVDGLGIHFVHVRGRGPAPIPLVLTHGWPSSFIELEAVAGPLADPASHG
HHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEECCCCCHHEEHHHHHCCCCCCHHCC
GDARDAFDVVIPSMPGFGFSDRPTARGFVRVDRLWRKLMTQVLGYPWFVAHGTDVGARVT
CCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHH
SALGRFQADVVRGIHLGSVDLEWPDPPPDAASMTAAERDYVARCARWEKEQGAYGELQAT
HHHHHHHHHHHHCEEECCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEECC
TPQTAAYGLNDSPAALAAWIVEKYRAWSDCGGEVERRFSKDTLLTNVVVYWATQTINSSM
CCCHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRYYEVRHDPQPPLRPGERIEAPASIAMFPGERDLLVPREWAERCYHVRRWTNMPRGGHF
HHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
PALEEPELLVQDLRESFRPLRGS
CCCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MEPFAIDVPEAVLHDLRERLRATRWPDAVEGAGWDYGADLAYMQELVAYWVDRFDWRAQE
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RRLNQLPQFRARVDGLGIHFVHVRGRGPAPIPLVLTHGWPSSFIELEAVAGPLADPASHG
HHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEECCCCCHHEEHHHHHCCCCCCHHCC
GDARDAFDVVIPSMPGFGFSDRPTARGFVRVDRLWRKLMTQVLGYPWFVAHGTDVGARVT
CCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHH
SALGRFQADVVRGIHLGSVDLEWPDPPPDAASMTAAERDYVARCARWEKEQGAYGELQAT
HHHHHHHHHHHHCEEECCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEECC
TPQTAAYGLNDSPAALAAWIVEKYRAWSDCGGEVERRFSKDTLLTNVVVYWATQTINSSM
CCCHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRYYEVRHDPQPPLRPGERIEAPASIAMFPGERDLLVPREWAERCYHVRRWTNMPRGGHF
HHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
PALEEPELLVQDLRESFRPLRGS
CCCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226695 [H]