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The map label for this gene is mre11 [H]

Identifier: 220916758

GI number: 220916758

Start: 1845806

End: 1846618

Strand: Reverse

Name: mre11 [H]

Synonym: A2cp1_1653

Alternate gene names: 220916758

Gene position: 1846618-1845806 (Counterclockwise)

Preceding gene: 220916759

Following gene: 220916757

Centisome position: 36.72

GC content: 76.38

Gene sequence:

>813_bases
ATGCGACTCCTCTTCCTCTCCGACACGCACCTCGGCCACGACCTGCCCGCGCGTCCCCGCACGTCGCGGCCGCGGCGCGG
GGCCGAGTTCTTCGAGAGCTTCGAGGCGGCGCTCGCGCCCGCCCGCGCCGGCGAGGTGGATGCGGTGCTGCACGCCGGCG
ACCTCCTGTACCGGAGCCGGGTGCCGGCGTGGCTCTCGGACGCGGCGCTGGCGCCCCTCCGCGCCGTCGCCGACGCGGGG
ATCCCGGTGCTGCTGCTCCCCGGCAACCACGAACGCGGACAGCTCCCCCACCCGCTCCTCGCGTGCCACCGCAACCTCCA
CGTGTTCGACCGCCCGCGCACCGTCGTGCTGGAGGCCGGCGGCGTTCGGGTCGCGTTCGCCGGGTTCCCGTACGCGCGCG
AGGTGCGGGGCCGCTTCGCGGCCCTCCTCGACGCGGCGACCGCCGGGGCGCCGTCCGGAGACGTGCGGGTCCTCTGCCTC
CACCACTGCGTCGAGGGCGCCACCGTCGGGCCCACCGACTTCACCTTCCGCGACGGGCCCGACGTGATCCCGCGCTCTGC
CCTGCCGACCGGCTTCGCGGCGGTCCTCTGCGGCCACGTGCACCGGCACCAGGTCCTCCGCGCGGACGGTGTGCCGCCCG
TCATCTATGCCGGGTCCACCGAGCGGACCTCGTCGGCCGAGGCCGGCGAGACGAAGGGCATCGTCCTGCTCTGGTTCTCG
GAGGCCGGGCTCGAGCGGTACCGGTTCCGCCCGCTCCCCCTGCACGCGCCGCCGCCCCGGTTCCGCCGGGGCGCGCCAAG
CCCTTGCGGTTGA

Upstream 100 bases:

>100_bases
TTGCGCGGCAGCTGACGCGCGCCACGGCGATCGCCGACCCGCCTCGGCTGTCAGACGGAGCCTGTACATCCGTTCCGTCT
CGCACGCGAGGCCGGCGGCC

Downstream 100 bases:

>100_bases
AGCGATCGCACGCTACGAGAACGGCCGCACGGGGAGGCGCATGAGCCGTTATCTGGTGCTGCTTCGCGGGATCAACGTCG
GCGGCAAGAACCTCATCGGC

Product: metallophosphoesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MRLLFLSDTHLGHDLPARPRTSRPRRGAEFFESFEAALAPARAGEVDAVLHAGDLLYRSRVPAWLSDAALAPLRAVADAG
IPVLLLPGNHERGQLPHPLLACHRNLHVFDRPRTVVLEAGGVRVAFAGFPYAREVRGRFAALLDAATAGAPSGDVRVLCL
HHCVEGATVGPTDFTFRDGPDVIPRSALPTGFAAVLCGHVHRHQVLRADGVPPVIYAGSTERTSSAEAGETKGIVLLWFS
EAGLERYRFRPLPLHAPPPRFRRGAPSPCG

Sequences:

>Translated_270_residues
MRLLFLSDTHLGHDLPARPRTSRPRRGAEFFESFEAALAPARAGEVDAVLHAGDLLYRSRVPAWLSDAALAPLRAVADAG
IPVLLLPGNHERGQLPHPLLACHRNLHVFDRPRTVVLEAGGVRVAFAGFPYAREVRGRFAALLDAATAGAPSGDVRVLCL
HHCVEGATVGPTDFTFRDGPDVIPRSALPTGFAAVLCGHVHRHQVLRADGVPPVIYAGSTERTSSAEAGETKGIVLLWFS
EAGLERYRFRPLPLHAPPPRFRRGAPSPCG
>Mature_270_residues
MRLLFLSDTHLGHDLPARPRTSRPRRGAEFFESFEAALAPARAGEVDAVLHAGDLLYRSRVPAWLSDAALAPLRAVADAG
IPVLLLPGNHERGQLPHPLLACHRNLHVFDRPRTVVLEAGGVRVAFAGFPYAREVRGRFAALLDAATAGAPSGDVRVLCL
HHCVEGATVGPTDFTFRDGPDVIPRSALPTGFAAVLCGHVHRHQVLRADGVPPVIYAGSTERTSSAEAGETKGIVLLWFS
EAGLERYRFRPLPLHAPPPRFRRGAPSPCG

Specific function: Involved in DNA double-strand break repair (DSBR). The rad50/mre11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific 3'-5' exonuclease activity [H]

COG id: COG0420

COG function: function code L; DNA repair exonuclease

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MRE11/RAD32 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: NA

Molecular weight: Translated: 29071; Mature: 29071

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLFLSDTHLGHDLPARPRTSRPRRGAEFFESFEAALAPARAGEVDAVLHAGDLLYRSR
CEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHC
VPAWLSDAALAPLRAVADAGIPVLLLPGNHERGQLPHPLLACHRNLHVFDRPRTVVLEAG
CCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHCCCCEEECCCCEEEEECC
GVRVAFAGFPYAREVRGRFAALLDAATAGAPSGDVRVLCLHHCVEGATVGPTDFTFRDGP
CEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHCCCCCCCCCCCCCCCC
DVIPRSALPTGFAAVLCGHVHRHQVLRADGVPPVIYAGSTERTSSAEAGETKGIVLLWFS
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCEEEEEEC
EAGLERYRFRPLPLHAPPPRFRRGAPSPCG
CCCHHHHCCCCCCCCCCCHHHHCCCCCCCC
>Mature Secondary Structure
MRLLFLSDTHLGHDLPARPRTSRPRRGAEFFESFEAALAPARAGEVDAVLHAGDLLYRSR
CEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHC
VPAWLSDAALAPLRAVADAGIPVLLLPGNHERGQLPHPLLACHRNLHVFDRPRTVVLEAG
CCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHCCCCEEECCCCEEEEECC
GVRVAFAGFPYAREVRGRFAALLDAATAGAPSGDVRVLCLHHCVEGATVGPTDFTFRDGP
CEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHCCCCCCCCCCCCCCCC
DVIPRSALPTGFAAVLCGHVHRHQVLRADGVPPVIYAGSTERTSSAEAGETKGIVLLWFS
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCEEEEEEC
EAGLERYRFRPLPLHAPPPRFRRGAPSPCG
CCCHHHHCCCCCCCCCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA