Definition Anaeromyxobacter dehalogenans 2CP-1 chromosome, complete genome.
Accession NC_011891
Length 5,029,329

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The map label for this gene is abcA [H]

Identifier: 220916600

GI number: 220916600

Start: 1669727

End: 1670491

Strand: Direct

Name: abcA [H]

Synonym: A2cp1_1494

Alternate gene names: 220916600

Gene position: 1669727-1670491 (Clockwise)

Preceding gene: 220916599

Following gene: 220916601

Centisome position: 33.2

GC content: 73.73

Gene sequence:

>765_bases
ATGACCGGGACCATCACCTTCGAGGACGTGGGGATGTGCTACCGCCTGCACCGGGAGCGGGTGCGCTCGCTCAAGGAGGC
GGTGCTGGGCGGCTTCCGGCACCTGCGCGAGGCGGACGAGCTGTGGGCGCTGCGCGGCGTGAGCTTCGAGGTGCGTCCCG
GCGAGGCGGTCGGGCTGGTGGGCGCGAACGGCTCGGGGAAGAGCACGCTCCTCAAGCTCGCGGCCGGCGTGCTGCGCCCG
ACCGAGGGCCGGGTGCGGGTGGAGGGTCGGGTGGCGCCCATCATCGAGCTCGCCGCCGGGTTCGACCCCGAGCTGTCCGG
CCGGGACAACGTGTTCCTGAACGGCGCGCTGATGGGCCGGGCCCGGCGCGACATGGCCCGGCGGCTGGAGCGGATCTTCG
CGTTCGCCGAGCTGGAGGGCTTCGAGGACGTGCCGGTGAAGAATTACAGCTCCGGCATGTACGCGCGGCTCGGGTTCGCC
ATCGCGGTGGACGTCGAGCCGGAGATCCTGGTGGTGGACGAGGTCCTGGCGGTGGGCGACGAGCGCTTCCAGGCGCGCTG
CCTGGAGCGGATCCGCGCGCTGCTCGCCGGCGGGACCACGCTGTTCCTCGTCTCGCACCAGATGGACCAGGTGGCGGAGG
TGTGCCGGCGGGTGCTGCTCCTCCACCGGGGCGGCGTGTGCCACGACGGCGCGCCGGCCGACGCCATCCGGCGCTACCGG
GAGCTGCAGGGCTTCACGCCGCCGCCGGTGGCGCGGACCGGCTGA

Upstream 100 bases:

>100_bases
TCCACCGTCGCGTTCGCGCTGCTGGCCGCCCTCGTCTCGCTCGCGGTCGGGGGCGCGGTGTTCACCCGCTGCGAGCACGG
CCACATCCACCATCTCTGAC

Downstream 100 bases:

>100_bases
GCGGAGGGCGCGTGGGCGAGGCGGTGCTCGCGGTGGCGGGCGGGGCCGAGCGCGCGCGGCGCGCGGGGGTGGCGCTCGGC
CGCGGCGCGGCGCTGGTCGC

Product: ABC transporter-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MTGTITFEDVGMCYRLHRERVRSLKEAVLGGFRHLREADELWALRGVSFEVRPGEAVGLVGANGSGKSTLLKLAAGVLRP
TEGRVRVEGRVAPIIELAAGFDPELSGRDNVFLNGALMGRARRDMARRLERIFAFAELEGFEDVPVKNYSSGMYARLGFA
IAVDVEPEILVVDEVLAVGDERFQARCLERIRALLAGGTTLFLVSHQMDQVAEVCRRVLLLHRGGVCHDGAPADAIRRYR
ELQGFTPPPVARTG

Sequences:

>Translated_254_residues
MTGTITFEDVGMCYRLHRERVRSLKEAVLGGFRHLREADELWALRGVSFEVRPGEAVGLVGANGSGKSTLLKLAAGVLRP
TEGRVRVEGRVAPIIELAAGFDPELSGRDNVFLNGALMGRARRDMARRLERIFAFAELEGFEDVPVKNYSSGMYARLGFA
IAVDVEPEILVVDEVLAVGDERFQARCLERIRALLAGGTTLFLVSHQMDQVAEVCRRVLLLHRGGVCHDGAPADAIRRYR
ELQGFTPPPVARTG
>Mature_253_residues
TGTITFEDVGMCYRLHRERVRSLKEAVLGGFRHLREADELWALRGVSFEVRPGEAVGLVGANGSGKSTLLKLAAGVLRPT
EGRVRVEGRVAPIIELAAGFDPELSGRDNVFLNGALMGRARRDMARRLERIFAFAELEGFEDVPVKNYSSGMYARLGFAI
AVDVEPEILVVDEVLAVGDERFQARCLERIRALLAGGTTLFLVSHQMDQVAEVCRRVLLLHRGGVCHDGAPADAIRRYRE
LQGFTPPPVARTG

Specific function: Influences the expression of the surface array protein gene (vapA). May have both regulatory and transport activities [H]

COG id: COG1134

COG function: function code GM; ABC-type polysaccharide/polyol phosphate transport system, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI153792144, Length=198, Percent_Identity=28.2828282828283, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI6005701, Length=190, Percent_Identity=30, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI27477115, Length=190, Percent_Identity=30, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI45446740, Length=200, Percent_Identity=28, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI27436953, Length=190, Percent_Identity=26.3157894736842, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI47078218, Length=185, Percent_Identity=29.1891891891892, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI31657092, Length=226, Percent_Identity=26.5486725663717, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI27262624, Length=195, Percent_Identity=27.1794871794872, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI27262626, Length=195, Percent_Identity=27.1794871794872, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI105990541, Length=186, Percent_Identity=27.4193548387097, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI157502203, Length=205, Percent_Identity=28.2926829268293, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI157502201, Length=205, Percent_Identity=28.2926829268293, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI21729876, Length=205, Percent_Identity=26.8292682926829, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI21729873, Length=205, Percent_Identity=26.8292682926829, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI15149474, Length=205, Percent_Identity=26.8292682926829, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI27881501, Length=194, Percent_Identity=22.1649484536082, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI30795238, Length=194, Percent_Identity=22.1649484536082, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI150417984, Length=239, Percent_Identity=24.6861924686192, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87081709, Length=207, Percent_Identity=28.0193236714976, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI87081782, Length=207, Percent_Identity=29.951690821256, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI48994943, Length=211, Percent_Identity=28.9099526066351, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI48995001, Length=207, Percent_Identity=29.4685990338164, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1786398, Length=205, Percent_Identity=29.2682926829268, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1786319, Length=200, Percent_Identity=26.5, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1789873, Length=230, Percent_Identity=28.695652173913, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787547, Length=216, Percent_Identity=25.9259259259259, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI87081791, Length=210, Percent_Identity=23.8095238095238, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788761, Length=211, Percent_Identity=26.5402843601896, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1788450, Length=213, Percent_Identity=27.2300469483568, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787792, Length=220, Percent_Identity=24.5454545454545, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1789032, Length=238, Percent_Identity=26.0504201680672, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI48994997, Length=206, Percent_Identity=30.0970873786408, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788210, Length=200, Percent_Identity=25, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1787370, Length=244, Percent_Identity=21.7213114754098, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1787029, Length=221, Percent_Identity=25.3393665158371, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87082267, Length=208, Percent_Identity=24.0384615384615, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790190, Length=199, Percent_Identity=25.1256281407035, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI87082064, Length=196, Percent_Identity=32.6530612244898, Blast_Score=61, Evalue=6e-11,
Organism=Escherichia coli, GI1788165, Length=194, Percent_Identity=28.8659793814433, Blast_Score=60, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=204, Percent_Identity=26.4705882352941, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17565586, Length=196, Percent_Identity=26.0204081632653, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71983523, Length=202, Percent_Identity=25.7425742574257, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71983516, Length=202, Percent_Identity=25.7425742574257, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71983510, Length=202, Percent_Identity=25.7425742574257, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17569081, Length=200, Percent_Identity=26, Blast_Score=64, Evalue=9e-11,
Organism=Drosophila melanogaster, GI221500365, Length=191, Percent_Identity=30.8900523560209, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI116007184, Length=203, Percent_Identity=30.5418719211823, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI221512771, Length=194, Percent_Identity=29.3814432989691, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24666092, Length=233, Percent_Identity=26.1802575107296, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: 3.6.3.30 [C]

Molecular weight: Translated: 27913; Mature: 27781

Theoretical pI: Translated: 7.98; Mature: 7.98

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MTGTITFEDVGMCYRLHRERVRSLKEAVLGGFRHLREADELWALRGVSFEVRPGEAVGLV
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEE
GANGSGKSTLLKLAAGVLRPTEGRVRVEGRVAPIIELAAGFDPELSGRDNVFLNGALMGR
ECCCCCHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHCCCCCCCCCCCCEEECHHHHHH
ARRDMARRLERIFAFAELEGFEDVPVKNYSSGMYARLGFAIAVDVEPEILVVDEVLAVGD
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEEEECCCCEEEHHHHHHHCC
ERFQARCLERIRALLAGGTTLFLVSHQMDQVAEVCRRVLLLHRGGVCHDGAPADAIRRYR
HHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
ELQGFTPPPVARTG
HHCCCCCCCCCCCC
>Mature Secondary Structure 
TGTITFEDVGMCYRLHRERVRSLKEAVLGGFRHLREADELWALRGVSFEVRPGEAVGLV
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEE
GANGSGKSTLLKLAAGVLRPTEGRVRVEGRVAPIIELAAGFDPELSGRDNVFLNGALMGR
ECCCCCHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHCCCCCCCCCCCCEEECHHHHHH
ARRDMARRLERIFAFAELEGFEDVPVKNYSSGMYARLGFAIAVDVEPEILVVDEVLAVGD
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEEEECCCCEEEHHHHHHHCC
ERFQARCLERIRALLAGGTTLFLVSHQMDQVAEVCRRVLLLHRGGVCHDGAPADAIRRYR
HHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
ELQGFTPPPVARTG
HHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8491726 [H]