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The map label for this gene is 220916573

Identifier: 220916573

GI number: 220916573

Start: 1638694

End: 1639494

Strand: Direct

Name: 220916573

Synonym: A2cp1_1467

Alternate gene names: NA

Gene position: 1638694-1639494 (Clockwise)

Preceding gene: 220916572

Following gene: 220916577

Centisome position: 32.58

GC content: 77.03

Gene sequence:

>801_bases
ATGCTCATCGACCTGCACGTCCACAGCCATCACACCCGCGGTTGCGCGCTGGCGCCGCGGGACGTGGTGCGGCGGGCCCG
CGAGGCCGGCCTGGACGGCGTCGCCTTCACCGATCACGACACGCTCGAGGGGCTGGAGGAGATCCGGGCCGCCGCGCGGG
ACGAGGGGCTGGTCGCGCTGTGCGGCGTCGAGGTGACCACCGATCGCGGCCACTTCCTCTGCTTCTTCCCCGACCCCGCC
GCGGTGCCCGCGCCCGTCCAGCTGTTCGGCGCCGCGCGGCCCTGGCCCGTGCGCGAGGTGCTCGCGCGCGTGCGGCAGCT
CGGCGGCGCCGCGGTGGCCGCCCACCCCTACGACAAGACCGTGGAGCGCCCCTGCGGCGACGTGGTGTTCACGCTCGACG
GCCTGTCGGCGATCGAGGGGCTGAACGCGCGGCGCAAGGGACCCGCGAACGACCTCGCCATCGAGGCCGCCGATCACATG
AGCCTGCCCTGCACCGGCGGCTCCGGCGCGCACGAGCTCGCCGAGATCGGGAAGGCCGCGACGCTGTTCCGCGACCCCGT
GGCGAGCGAGGCGGACGTCGTCCGCCAGCTCCGCGCCGGCACGGTGTACTGCGTCGCCGTGGGCGTGACCCCCTCGGAGC
CCGATCGCGCACCCCGCGATCGCGGCGGCGAGCGAGGCGACCGCGGAGATCGCGGCGACCGGGGCGGCCACCGAGGGCAC
GGGCACGGCCGCGGCCGAGGGCACGGCGGCGGTGGTGGCAGTGGCGGTGGCGGCCACGGTGGCGAGCGCCGCCGGCGCTA
G

Upstream 100 bases:

>100_bases
GCGCTCGCCTGAGCGGCCCGGGCGCGGGGCGTCGCGTCCTTCAAAAGCCGCGCGGCGCGTGCTAAGGCACCGGGACCGAT
CCGCACCCCGGGGCGACGCC

Downstream 100 bases:

>100_bases
GCGCCGGTCCCCGAACGCAGCTCCGAGCTCGGCCCAGGTCGCGCGAGAGCGTCTCGGCCCGAGCTGCCGCGCCGAGCGAA
GGTGTACGCGTCCATCACCC

Product: PHP domain-containing protein

Products: AMP; diphosphate; L-isoleucyl-tRNA(Ile)

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MLIDLHVHSHHTRGCALAPRDVVRRAREAGLDGVAFTDHDTLEGLEEIRAAARDEGLVALCGVEVTTDRGHFLCFFPDPA
AVPAPVQLFGAARPWPVREVLARVRQLGGAAVAAHPYDKTVERPCGDVVFTLDGLSAIEGLNARRKGPANDLAIEAADHM
SLPCTGGSGAHELAEIGKAATLFRDPVASEADVVRQLRAGTVYCVAVGVTPSEPDRAPRDRGGERGDRGDRGDRGGHRGH
GHGRGRGHGGGGGSGGGGHGGERRRR

Sequences:

>Translated_266_residues
MLIDLHVHSHHTRGCALAPRDVVRRAREAGLDGVAFTDHDTLEGLEEIRAAARDEGLVALCGVEVTTDRGHFLCFFPDPA
AVPAPVQLFGAARPWPVREVLARVRQLGGAAVAAHPYDKTVERPCGDVVFTLDGLSAIEGLNARRKGPANDLAIEAADHM
SLPCTGGSGAHELAEIGKAATLFRDPVASEADVVRQLRAGTVYCVAVGVTPSEPDRAPRDRGGERGDRGDRGDRGGHRGH
GHGRGRGHGGGGGSGGGGHGGERRRR
>Mature_266_residues
MLIDLHVHSHHTRGCALAPRDVVRRAREAGLDGVAFTDHDTLEGLEEIRAAARDEGLVALCGVEVTTDRGHFLCFFPDPA
AVPAPVQLFGAARPWPVREVLARVRQLGGAAVAAHPYDKTVERPCGDVVFTLDGLSAIEGLNARRKGPANDLAIEAADHM
SLPCTGGSGAHELAEIGKAATLFRDPVASEADVVRQLRAGTVYCVAVGVTPSEPDRAPRDRGGERGDRGDRGDRGGHRGH
GHGRGRGHGGGGGSGGGGHGGERRRR

Specific function: Unknown

COG id: COG0613

COG function: function code R; Predicted metal-dependent phosphoesterases (PHP family)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.jannaschii MJ0417 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR016195 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: 6.1.1.5

Molecular weight: Translated: 27883; Mature: 27883

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIDLHVHSHHTRGCALAPRDVVRRAREAGLDGVAFTDHDTLEGLEEIRAAARDEGLVAL
CEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHCCCCEEEE
CGVEVTTDRGHFLCFFPDPAAVPAPVQLFGAARPWPVREVLARVRQLGGAAVAAHPYDKT
ECEEEECCCCCEEEECCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHCCCEEEECCCHHH
VERPCGDVVFTLDGLSAIEGLNARRKGPANDLAIEAADHMSLPCTGGSGAHELAEIGKAA
HHCCCCCEEEEECCHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHH
TLFRDPVASEADVVRQLRAGTVYCVAVGVTPSEPDRAPRDRGGERGDRGDRGDRGGHRGH
HHHHCCCCCHHHHHHHHHCCEEEEEEEECCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCC
GHGRGRGHGGGGGSGGGGHGGERRRR
CCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLIDLHVHSHHTRGCALAPRDVVRRAREAGLDGVAFTDHDTLEGLEEIRAAARDEGLVAL
CEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHCCCCEEEE
CGVEVTTDRGHFLCFFPDPAAVPAPVQLFGAARPWPVREVLARVRQLGGAAVAAHPYDKT
ECEEEECCCCCEEEECCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHCCCEEEECCCHHH
VERPCGDVVFTLDGLSAIEGLNARRKGPANDLAIEAADHMSLPCTGGSGAHELAEIGKAA
HHCCCCCEEEEECCHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHH
TLFRDPVASEADVVRQLRAGTVYCVAVGVTPSEPDRAPRDRGGERGDRGDRGDRGGHRGH
HHHHCCCCCHHHHHHHHHCCEEEEEEEECCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCC
GHGRGRGHGGGGGSGGGGHGGERRRR
CCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-isoleucine; tRNA(Ile)

Specific reaction: ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl-tRNA(Ile)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]