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The map label for this gene is yoaE [H]

Identifier: 220916437

GI number: 220916437

Start: 1481678

End: 1483681

Strand: Direct

Name: yoaE [H]

Synonym: A2cp1_1331

Alternate gene names: 220916437

Gene position: 1481678-1483681 (Clockwise)

Preceding gene: 220916436

Following gene: 220916438

Centisome position: 29.46

GC content: 75.55

Gene sequence:

>2004_bases
ATGCCCTCGCTCGCACGCTCCGTCTGCCCGTTCGACTGTCCCGACGCCTGCGGCCTGCTCGTCGAGGTCGAAGACGGGCG
CGCGGCGAAGGTCCGGGGCGACCCCGAGCACCCGTACTCGCAGGGCACCCTCTGCCCGAAGATGAACGGCTACGACCGGA
CGGTGCACTCGCCCGACCGGCTCACCCATCCTCTGATCCGGACCGGGCCGAAGGGCGCCGGGGCGTTCCGGCGCGCGACC
TGGGACGAGGCCGTCGCGCGGGTGGCCTCGCGCTGGAAGGAGATCCTGGCCGCCGACGGCGGCGAGGCGATCCTGCCCTA
CTCGTACGCGGGCTCCATGGGCCTGGTGCAGCGCAACGCCGGCTACCCGTTCTTCCATCGCCTGGGCGCGACGAAGCTGG
CGCGCACCATCTGCACGCCGGCCCAGGACGCCGGCTGGACCGCGGTGATGGGCGCCACCCCCGGGCCGGACCCGGACACG
GTGCTCGGCTCGGACCTGGTGGTGCTGTGGGGCATCAACGCGGTCGCCACCAGCATCCACTTCGCCCAGCGGGCCCGGGA
GGCGCGGCGCCGCGGCGCCAGGGTGCTGCTGGTGGACACCTACCGGAACGACACCGCCGCCCTGGCGGACGAGGTGATCC
TGGTCCGGCCCGGCTCCGACGGCATGCTCGCGCTCGGCCTCGTCCACGTGCTCGCGCGCGAGGGGCTGGCCGACGAGGCG
TTCCTGGCGAGCGAGACGGCCGGGTGGCCGGAGCTGAAGGCGGTCGCGCTGGCGGAGTGCCCGCCGGACGCGGTCGCGGC
CGCGACCGGGCTCGCGCCGGAGGCGATCGTGGCGCTGGCGCGGACGCTGGCGCGCGCGCGCGCGCCGTTCTTCCGGATCG
GCGGCGGGCCGTCGCGCTACGGCAACGGCGCCATGACCGTCCGGAGCGTGGTCGCGCTCGCGGCGGTGCTGGGCGCGTTC
GGCCGCGAGGGCGGCGGCTGCCTCACCTCGGCCGCCTCGTCGCAGGCGTTCGACCTCTCCCCGGTCCGCCGCGAGGACCT
GCTCGCGCGCCCGGTGCGCGAGGTGAACATGAACCGGCTGGGCTGGGCGCTGAACGAGCTGCGCGATCCGCCCATCCGCT
CGATGTACGTGTGGTGCTCGAACCCGGCCGCGGTCGCGCCGGACCAGAACGCGGTGCTGCGCGGCCTCTCGCGCGAGGAC
CTGTTCCTGGTGGTGCACGAGCGCTTCCTCACCGACACCGCGCGCCACGCGGACGTGGTGCTGCCGGCGACCACCTCGCT
CGAGCACCTCGACGTCTACCGCTCGTACGGCCACTACACGGTCCAGCGCGCCGCCGCGGTGATCCCGCCGCTGGGCGAGG
CGAAGCCGAACTGGGAGGTCTTCCAGCTCCTCGCCGCCGCCATGGGCTTCGACGAGCCGGTGTTCCGGACCAGCGCCGCC
GAGATGGCGGACCAGCTGCTCGCGCAGCGATCGGCGTGGTGGGACGCGGTGGACCGCTCGCGGCTCGCGGAGGGGAAGGC
GGTCCGCATCGCGCCGCCGCCCGGCCCGCGCTGGCGCACCGCCTCCGGCCGCATCGAGCTCGTGAACCCGGCGCTGCGCG
AGCCGGTGCCGCGGCCGCTCCCTGCCCACGCGGACCGCGATCCGCTGCCGCTCAGGCTCGTCACCGCGCCCGCGCTGTAC
ACGCTCAACTCCACCTTCCAGGAGCGGCCCGAGCTGCGCGCCAAGGCCGGCGGCATGCAGCTCCAGCTCGCGCCGTCCGA
GGCCGCCGCGCGCGGGCTCTCCGACGGCCAGCGGGTGGTGGCCTTCAACGGTCTCGGCGAGGCGGCGTTCGTGCTGCGCG
TCGCCGAGGGCGTCCCGGCGGGCGTGGCGGTGGCGGAGGGCGTGTTCTGGCTGGCGCACGCCCCGGGCGCACGGAACGTG
AATGCGCTCACCTCCCAGCGGCTCACCGACGAGGCGGGCGGCTCCACGTTCTACGACAACCGCGTGGACGTCCGGGCGGC
GTAG

Upstream 100 bases:

>100_bases
GGGCGCCCCCGCGCCCGGCGCGCGATCCGCCGCCCCGTCGCACGACGGGCCGCAGGACGGGTCGCGCCGCCGGCGGGCGT
CGATTATCCTCGCGCACGCC

Downstream 100 bases:

>100_bases
GCCGCCCGGGGCCGCGGCCCCGTCCCGAACCGTTCCGCTCCCCCGCCGGCTCCCGCCCGGACGGGCGAGCCGTGCCCGGC
GAGGGATCGTGCGGGGGCGA

Product: Formate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 667; Mature: 666

Protein sequence:

>667_residues
MPSLARSVCPFDCPDACGLLVEVEDGRAAKVRGDPEHPYSQGTLCPKMNGYDRTVHSPDRLTHPLIRTGPKGAGAFRRAT
WDEAVARVASRWKEILAADGGEAILPYSYAGSMGLVQRNAGYPFFHRLGATKLARTICTPAQDAGWTAVMGATPGPDPDT
VLGSDLVVLWGINAVATSIHFAQRAREARRRGARVLLVDTYRNDTAALADEVILVRPGSDGMLALGLVHVLAREGLADEA
FLASETAGWPELKAVALAECPPDAVAAATGLAPEAIVALARTLARARAPFFRIGGGPSRYGNGAMTVRSVVALAAVLGAF
GREGGGCLTSAASSQAFDLSPVRREDLLARPVREVNMNRLGWALNELRDPPIRSMYVWCSNPAAVAPDQNAVLRGLSRED
LFLVVHERFLTDTARHADVVLPATTSLEHLDVYRSYGHYTVQRAAAVIPPLGEAKPNWEVFQLLAAAMGFDEPVFRTSAA
EMADQLLAQRSAWWDAVDRSRLAEGKAVRIAPPPGPRWRTASGRIELVNPALREPVPRPLPAHADRDPLPLRLVTAPALY
TLNSTFQERPELRAKAGGMQLQLAPSEAAARGLSDGQRVVAFNGLGEAAFVLRVAEGVPAGVAVAEGVFWLAHAPGARNV
NALTSQRLTDEAGGSTFYDNRVDVRAA

Sequences:

>Translated_667_residues
MPSLARSVCPFDCPDACGLLVEVEDGRAAKVRGDPEHPYSQGTLCPKMNGYDRTVHSPDRLTHPLIRTGPKGAGAFRRAT
WDEAVARVASRWKEILAADGGEAILPYSYAGSMGLVQRNAGYPFFHRLGATKLARTICTPAQDAGWTAVMGATPGPDPDT
VLGSDLVVLWGINAVATSIHFAQRAREARRRGARVLLVDTYRNDTAALADEVILVRPGSDGMLALGLVHVLAREGLADEA
FLASETAGWPELKAVALAECPPDAVAAATGLAPEAIVALARTLARARAPFFRIGGGPSRYGNGAMTVRSVVALAAVLGAF
GREGGGCLTSAASSQAFDLSPVRREDLLARPVREVNMNRLGWALNELRDPPIRSMYVWCSNPAAVAPDQNAVLRGLSRED
LFLVVHERFLTDTARHADVVLPATTSLEHLDVYRSYGHYTVQRAAAVIPPLGEAKPNWEVFQLLAAAMGFDEPVFRTSAA
EMADQLLAQRSAWWDAVDRSRLAEGKAVRIAPPPGPRWRTASGRIELVNPALREPVPRPLPAHADRDPLPLRLVTAPALY
TLNSTFQERPELRAKAGGMQLQLAPSEAAARGLSDGQRVVAFNGLGEAAFVLRVAEGVPAGVAVAEGVFWLAHAPGARNV
NALTSQRLTDEAGGSTFYDNRVDVRAA
>Mature_666_residues
PSLARSVCPFDCPDACGLLVEVEDGRAAKVRGDPEHPYSQGTLCPKMNGYDRTVHSPDRLTHPLIRTGPKGAGAFRRATW
DEAVARVASRWKEILAADGGEAILPYSYAGSMGLVQRNAGYPFFHRLGATKLARTICTPAQDAGWTAVMGATPGPDPDTV
LGSDLVVLWGINAVATSIHFAQRAREARRRGARVLLVDTYRNDTAALADEVILVRPGSDGMLALGLVHVLAREGLADEAF
LASETAGWPELKAVALAECPPDAVAAATGLAPEAIVALARTLARARAPFFRIGGGPSRYGNGAMTVRSVVALAAVLGAFG
REGGGCLTSAASSQAFDLSPVRREDLLARPVREVNMNRLGWALNELRDPPIRSMYVWCSNPAAVAPDQNAVLRGLSREDL
FLVVHERFLTDTARHADVVLPATTSLEHLDVYRSYGHYTVQRAAAVIPPLGEAKPNWEVFQLLAAAMGFDEPVFRTSAAE
MADQLLAQRSAWWDAVDRSRLAEGKAVRIAPPPGPRWRTASGRIELVNPALREPVPRPLPAHADRDPLPLRLVTAPALYT
LNSTFQERPELRAKAGGMQLQLAPSEAAARGLSDGQRVVAFNGLGEAAFVLRVAEGVPAGVAVAEGVFWLAHAPGARNVN
ALTSQRLTDEAGGSTFYDNRVDVRAA

Specific function: Terminal Reductase During Anaerobic Growth On Various Sulfoxide And N-Oxide Compounds (By Similarity). [C]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cytoplasm Face Of The Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI171474008, Length=763, Percent_Identity=26.605504587156, Blast_Score=190, Evalue=3e-49,
Organism=Escherichia coli, GI87081797, Length=769, Percent_Identity=27.1781534460338, Blast_Score=184, Evalue=2e-47,
Organism=Escherichia coli, GI1787870, Length=763, Percent_Identity=24.9017038007864, Blast_Score=175, Evalue=8e-45,
Organism=Escherichia coli, GI3868721, Length=514, Percent_Identity=27.2373540856031, Blast_Score=146, Evalue=5e-36,
Organism=Escherichia coli, GI145693196, Length=685, Percent_Identity=26.8613138686131, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI87081994, Length=734, Percent_Identity=24.6594005449591, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1787231, Length=737, Percent_Identity=22.7951153324288, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788534, Length=532, Percent_Identity=23.4962406015038, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI3868720, Length=410, Percent_Identity=23.9024390243902, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI3868719, Length=409, Percent_Identity=22.7383863080685, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: 1.8.99.- [C]

Molecular weight: Translated: 71315; Mature: 71184

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: PS00490 MOLYBDOPTERIN_PROK_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSLARSVCPFDCPDACGLLVEVEDGRAAKVRGDPEHPYSQGTLCPKMNGYDRTVHSPDR
CCCHHHHCCCCCCCCCCCEEEEECCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
LTHPLIRTGPKGAGAFRRATWDEAVARVASRWKEILAADGGEAILPYSYAGSMGLVQRNA
HCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEECCC
GYPFFHRLGATKLARTICTPAQDAGWTAVMGATPGPDPDTVLGSDLVVLWGINAVATSIH
CCHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEEECHHHHHHHHH
FAQRAREARRRGARVLLVDTYRNDTAALADEVILVRPGSDGMLALGLVHVLAREGLADEA
HHHHHHHHHHCCCEEEEEEECCCCHHHHHCCEEEEECCCCCHHHHHHHHHHHHCCCCCHH
FLASETAGWPELKAVALAECPPDAVAAATGLAPEAIVALARTLARARAPFFRIGGGPSRY
HHHHCCCCCCHHHEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEECCCCCCC
GNGAMTVRSVVALAAVLGAFGREGGGCLTSAASSQAFDLSPVRREDLLARPVREVNMNRL
CCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHCHHHH
GWALNELRDPPIRSMYVWCSNPAAVAPDQNAVLRGLSREDLFLVVHERFLTDTARHADVV
HHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHCCCCCCEEEEEHHHHHHHHHCCCCEE
LPATTSLEHLDVYRSYGHYTVQRAAAVIPPLGEAKPNWEVFQLLAAAMGFDEPVFRTSAA
EECCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHH
EMADQLLAQRSAWWDAVDRSRLAEGKAVRIAPPPGPRWRTASGRIELVNPALREPVPRPL
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCEEEECHHHHCCCCCCC
PAHADRDPLPLRLVTAPALYTLNSTFQERPELRAKAGGMQLQLAPSEAAARGLSDGQRVV
CCCCCCCCCCEEEEECCHHEECCCHHHHCCHHHHHCCCEEEEECCHHHHHCCCCCCCEEE
AFNGLGEAAFVLRVAEGVPAGVAVAEGVFWLAHAPGARNVNALTSQRLTDEAGGSTFYDN
EECCCCHHHHHHHHHCCCCCCHHHHCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCEECC
RVDVRAA
CEEEEEC
>Mature Secondary Structure 
PSLARSVCPFDCPDACGLLVEVEDGRAAKVRGDPEHPYSQGTLCPKMNGYDRTVHSPDR
CCHHHHCCCCCCCCCCCEEEEECCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
LTHPLIRTGPKGAGAFRRATWDEAVARVASRWKEILAADGGEAILPYSYAGSMGLVQRNA
HCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEECCC
GYPFFHRLGATKLARTICTPAQDAGWTAVMGATPGPDPDTVLGSDLVVLWGINAVATSIH
CCHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEEECHHHHHHHHH
FAQRAREARRRGARVLLVDTYRNDTAALADEVILVRPGSDGMLALGLVHVLAREGLADEA
HHHHHHHHHHCCCEEEEEEECCCCHHHHHCCEEEEECCCCCHHHHHHHHHHHHCCCCCHH
FLASETAGWPELKAVALAECPPDAVAAATGLAPEAIVALARTLARARAPFFRIGGGPSRY
HHHHCCCCCCHHHEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEECCCCCCC
GNGAMTVRSVVALAAVLGAFGREGGGCLTSAASSQAFDLSPVRREDLLARPVREVNMNRL
CCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHCHHHH
GWALNELRDPPIRSMYVWCSNPAAVAPDQNAVLRGLSREDLFLVVHERFLTDTARHADVV
HHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHCCCCCCEEEEEHHHHHHHHHCCCCEE
LPATTSLEHLDVYRSYGHYTVQRAAAVIPPLGEAKPNWEVFQLLAAAMGFDEPVFRTSAA
EECCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHH
EMADQLLAQRSAWWDAVDRSRLAEGKAVRIAPPPGPRWRTASGRIELVNPALREPVPRPL
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCEEEECHHHHCCCCCCC
PAHADRDPLPLRLVTAPALYTLNSTFQERPELRAKAGGMQLQLAPSEAAARGLSDGQRVV
CCCCCCCCCCEEEEECCHHEECCCHHHHCCHHHHHCCCEEEEECCHHHHHCCCCCCCEEE
AFNGLGEAAFVLRVAEGVPAGVAVAEGVFWLAHAPGARNVNALTSQRLTDEAGGSTFYDN
EECCCCHHHHHHHHHCCCCCCHHHHCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCEECC
RVDVRAA
CEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: May Bind 4Fe-4S Cluster. [C]

Metal ions: Fe; Mo [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]