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The map label for this gene is fabZ

Identifier: 220916318

GI number: 220916318

Start: 1362464

End: 1362934

Strand: Direct

Name: fabZ

Synonym: A2cp1_1212

Alternate gene names: 220916318

Gene position: 1362464-1362934 (Clockwise)

Preceding gene: 220916317

Following gene: 220916319

Centisome position: 27.09

GC content: 70.7

Gene sequence:

>471_bases
ATGAGCGAGAGCGCGGAGCGCAAGTCGATCCTCGACGTGGTCGGGATCCAGAAGCTGCTGCCGCACCGGCCGCCGTTCCT
GCTGGTGGACCGGGTGGTGGAGTTCGAGGCGCACCGGCGGCTGGTGGCGCTGAAGGGCGTCACCATGAACGAGCCGTTCT
TCCAGGGGCACTTCCCGGCCCAGCCGGTGATGCCCGGGGTGCTCATCCTGGAGGCGCTCGCCCAGGCGGCCGCGCTGCTC
GCCACGATGTCCCTGCAGCCCGACGAGGTGAAGGACAAGATCACCTACCTCATGGGCATCGACGGGGCGCGCTTCCGCCG
CCCGGTGGTGCCGGGCGACCGGCTCGAGCTCGAGGTCGAGGTGACGAAGCAGAAGGGCGCCGTCTGGAAGCAGACCGGCG
TCGCGCGCGTCGACGGCCAGGTGGTCGCCGAGGCCGAGTTCATGGCGATGCTCGCCGACCGCGAGCGGTAG

Upstream 100 bases:

>100_bases
CGATGGCGTCGCTCGATCACCTGCACGACATGCGCAAGGAACTGCGCAGCCTGCGCCGCGAGGTGGAGCGGCTGCGCGCG
GACGCCGGCGAGGACGAGCC

Downstream 100 bases:

>100_bases
CAGACGATCGAGGAGCACGGGCGTCATGGCAATCCACCCCACCGCCATCGTCGAGGCCGGCGCGCAGGTCGATCCGTCCT
GCGACATCGGCCCGTACGCC

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 156; Mature: 155

Protein sequence:

>156_residues
MSESAERKSILDVVGIQKLLPHRPPFLLVDRVVEFEAHRRLVALKGVTMNEPFFQGHFPAQPVMPGVLILEALAQAAALL
ATMSLQPDEVKDKITYLMGIDGARFRRPVVPGDRLELEVEVTKQKGAVWKQTGVARVDGQVVAEAEFMAMLADRER

Sequences:

>Translated_156_residues
MSESAERKSILDVVGIQKLLPHRPPFLLVDRVVEFEAHRRLVALKGVTMNEPFFQGHFPAQPVMPGVLILEALAQAAALL
ATMSLQPDEVKDKITYLMGIDGARFRRPVVPGDRLELEVEVTKQKGAVWKQTGVARVDGQVVAEAEFMAMLADRER
>Mature_155_residues
SESAERKSILDVVGIQKLLPHRPPFLLVDRVVEFEAHRRLVALKGVTMNEPFFQGHFPAQPVMPGVLILEALAQAAALLA
TMSLQPDEVKDKITYLMGIDGARFRRPVVPGDRLELEVEVTKQKGAVWKQTGVARVDGQVVAEAEFMAMLADRER

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=142, Percent_Identity=54.9295774647887, Blast_Score=147, Evalue=4e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_ANAD2 (B8JFW8)

Other databases:

- EMBL:   CP001359
- RefSeq:   YP_002491622.1
- ProteinModelPortal:   B8JFW8
- SMR:   B8JFW8
- GeneID:   7299078
- GenomeReviews:   CP001359_GR
- KEGG:   acp:A2cp1_1212
- HOGENOM:   HBG433282
- ProtClustDB:   PRK00006
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 17343; Mature: 17211

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: ACT_SITE 57-57

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESAERKSILDVVGIQKLLPHRPPFLLVDRVVEFEAHRRLVALKGVTMNEPFFQGHFPA
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCC
QPVMPGVLILEALAQAAALLATMSLQPDEVKDKITYLMGIDGARFRRPVVPGDRLELEVE
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHCCCCCCCCCEEEEEE
VTKQKGAVWKQTGVARVDGQVVAEAEFMAMLADRER
EECCCCCEEHHCCCEECCCEEHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SESAERKSILDVVGIQKLLPHRPPFLLVDRVVEFEAHRRLVALKGVTMNEPFFQGHFPA
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCC
QPVMPGVLILEALAQAAALLATMSLQPDEVKDKITYLMGIDGARFRRPVVPGDRLELEVE
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHCCCCCCCCCEEEEEE
VTKQKGAVWKQTGVARVDGQVVAEAEFMAMLADRER
EECCCCCEEHHCCCEECCCEEHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA