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The map label for this gene is ilvE [H]

Identifier: 220916286

GI number: 220916286

Start: 1317872

End: 1318786

Strand: Reverse

Name: ilvE [H]

Synonym: A2cp1_1179

Alternate gene names: 220916286

Gene position: 1318786-1317872 (Counterclockwise)

Preceding gene: 220916287

Following gene: 220916285

Centisome position: 26.22

GC content: 70.6

Gene sequence:

>915_bases
ATGATCAAGGCGGACAGGATCTGGCTCGACGGCAAGCTCGTCGCCTTCGAGGACGCGAAGGTCCACGTCCTCACCCACGC
GCTCCACTACGGCATCGGCGTGTTCGAGGGCATCCGCGCCTACGAGCAGGCCGGCGGGGGCTCGGCGGTGTTCCGCCTGC
GCGAGCACATCCAGCGCCTGTTCGACTCGGCGCGCATCATGCTCATGGACCTCCCGTTCGCGCCCGGCGACGTCGAGCGC
GCCTGCGTCGACGTGCTGAAGGCGAACGGCCTGAAGGCCGGCTACATCCGCCCGCTCGCGTTCTTCGGCACCGGCTCCAT
GGGCGTCGGCGCGCCGAACCCGGTGCAGGTGCTGGTCGCGGCGTGGCCCTGGGGCGCCTACCTCTCCGAGGAGGGCATGG
CGAAGGGCATCCGCGCCAAGGTCTCGTCCATCGCCCGGCTCCACATCGGCGGCCAGATGGTGCGCGCCAAGGTGTCCGGC
CAGTACGTGAACTCGTTCCTCGCCACCCGGGAGGCGGCGCTCGCCGGCTACGACGAGGCGATCCTGCTCGACGCGGACGG
CTACGTGGCCGAGGGCTCGGGCGAGAACGTCTTCATCGTGAAGAACGGCGTGCTGCAGACGCCGCCGCTCTCCTCCCCGG
TGCTGGACGGCATCACCCGGAACGCGGTGCTCCGCCTCGCCGCCGACCTGGGCATCCCGGTGAAGGAGGAGAAGTTCACC
CGCGACACCGCCTACCTCGCCGACGAGCTGTTCCTCACCGGCACCGCCGCCGAGGTCACCCCGGTCCGCGAGCTCGACAA
CCGGCGCATCGGCAAGGGCGAGCCCGGGCCGGTGACGAAGCGGATCTCCGAGGCGTTCTTCAAGGCGGTCGGCGGCGAGG
ATCCGAAGCACCGGGAGTGGCTCACGCCCTACTAG

Upstream 100 bases:

>100_bases
GCTCCACCGGCGGTGCGCCCCCGCGCATCGTGCGATTGAATCCCGCGGCGCGTTGGGGCATCTTCGTCGACCCACTCCCA
CCAACCTCGGAAGGGCCACG

Downstream 100 bases:

>100_bases
GGGCCCGCGCGCCCGCGCCGAGCCCCATCAGGGCTCCCACGGGCGAGCCACCACACATCCTCCCGACACGAGGGCCGTTT
TCCGGGCGGTTGCCCCCGGA

Product: branched-chain amino acid aminotransferase

Products: NA

Alternate protein names: BCAT [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MIKADRIWLDGKLVAFEDAKVHVLTHALHYGIGVFEGIRAYEQAGGGSAVFRLREHIQRLFDSARIMLMDLPFAPGDVER
ACVDVLKANGLKAGYIRPLAFFGTGSMGVGAPNPVQVLVAAWPWGAYLSEEGMAKGIRAKVSSIARLHIGGQMVRAKVSG
QYVNSFLATREAALAGYDEAILLDADGYVAEGSGENVFIVKNGVLQTPPLSSPVLDGITRNAVLRLAADLGIPVKEEKFT
RDTAYLADELFLTGTAAEVTPVRELDNRRIGKGEPGPVTKRISEAFFKAVGGEDPKHREWLTPY

Sequences:

>Translated_304_residues
MIKADRIWLDGKLVAFEDAKVHVLTHALHYGIGVFEGIRAYEQAGGGSAVFRLREHIQRLFDSARIMLMDLPFAPGDVER
ACVDVLKANGLKAGYIRPLAFFGTGSMGVGAPNPVQVLVAAWPWGAYLSEEGMAKGIRAKVSSIARLHIGGQMVRAKVSG
QYVNSFLATREAALAGYDEAILLDADGYVAEGSGENVFIVKNGVLQTPPLSSPVLDGITRNAVLRLAADLGIPVKEEKFT
RDTAYLADELFLTGTAAEVTPVRELDNRRIGKGEPGPVTKRISEAFFKAVGGEDPKHREWLTPY
>Mature_304_residues
MIKADRIWLDGKLVAFEDAKVHVLTHALHYGIGVFEGIRAYEQAGGGSAVFRLREHIQRLFDSARIMLMDLPFAPGDVER
ACVDVLKANGLKAGYIRPLAFFGTGSMGVGAPNPVQVLVAAWPWGAYLSEEGMAKGIRAKVSSIARLHIGGQMVRAKVSG
QYVNSFLATREAALAGYDEAILLDADGYVAEGSGENVFIVKNGVLQTPPLSSPVLDGITRNAVLRLAADLGIPVKEEKFT
RDTAYLADELFLTGTAAEVTPVRELDNRRIGKGEPGPVTKRISEAFFKAVGGEDPKHREWLTPY

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI50658084, Length=298, Percent_Identity=26.1744966442953, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI296010906, Length=280, Percent_Identity=27.8571428571429, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI38176287, Length=280, Percent_Identity=27.8571428571429, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI296010904, Length=280, Percent_Identity=27.8571428571429, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI48994963, Length=301, Percent_Identity=50.4983388704319, Blast_Score=297, Evalue=5e-82,
Organism=Caenorhabditis elegans, GI17565728, Length=284, Percent_Identity=27.8169014084507, Blast_Score=88, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6322608, Length=330, Percent_Identity=25.1515151515152, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322002, Length=262, Percent_Identity=29.7709923664122, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641779, Length=282, Percent_Identity=25.177304964539, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 32892; Mature: 32892

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKADRIWLDGKLVAFEDAKVHVLTHALHYGIGVFEGIRAYEQAGGGSAVFRLREHIQRL
CCCCCEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
FDSARIMLMDLPFAPGDVERACVDVLKANGLKAGYIRPLAFFGTGSMGVGAPNPVQVLVA
HHCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEE
AWPWGAYLSEEGMAKGIRAKVSSIARLHIGGQMVRAKVSGQYVNSFLATREAALAGYDEA
ECCCCHHHCHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCE
ILLDADGYVAEGSGENVFIVKNGVLQTPPLSSPVLDGITRNAVLRLAADLGIPVKEEKFT
EEEECCCEEECCCCCEEEEEECCEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHH
RDTAYLADELFLTGTAAEVTPVRELDNRRIGKGEPGPVTKRISEAFFKAVGGEDPKHREW
HHHHHHHHHHEEECCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
LTPY
CCCC
>Mature Secondary Structure
MIKADRIWLDGKLVAFEDAKVHVLTHALHYGIGVFEGIRAYEQAGGGSAVFRLREHIQRL
CCCCCEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
FDSARIMLMDLPFAPGDVERACVDVLKANGLKAGYIRPLAFFGTGSMGVGAPNPVQVLVA
HHCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEE
AWPWGAYLSEEGMAKGIRAKVSSIARLHIGGQMVRAKVSGQYVNSFLATREAALAGYDEA
ECCCCHHHCHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCE
ILLDADGYVAEGSGENVFIVKNGVLQTPPLSSPVLDGITRNAVLRLAADLGIPVKEEKFT
EEEECCCEEECCCCCEEEEEECCEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHH
RDTAYLADELFLTGTAAEVTPVRELDNRRIGKGEPGPVTKRISEAFFKAVGGEDPKHREW
HHHHHHHHHHEEECCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
LTPY
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]