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The map label for this gene is ruvB

Identifier: 220916124

GI number: 220916124

Start: 1137270

End: 1138298

Strand: Direct

Name: ruvB

Synonym: A2cp1_1011

Alternate gene names: 220916124

Gene position: 1137270-1138298 (Clockwise)

Preceding gene: 220916123

Following gene: 220916126

Centisome position: 22.61

GC content: 74.44

Gene sequence:

>1029_bases
ATGACCGTGAAGCCGCTCCGCGACGTGACCCCGAAGCCGCTCGAGGGCGAGGAGCGCCTGGAGCAGTCGCTCCGCCCGGC
CACCTTCGACGACTACGTCGGCCAGGTGAAGATCGTCGACAACGTGAAGGTGTACGCCGCCGCCGCCCGCCAGCGCGGCG
AGTCGCTCGACCACGTGCTGCTCTCCGGCCCGCCCGGCCTGGGCAAGACCTCGCTCGCCCACATCCTGGCGCGCGAGCTG
GGCGTCACCCTGCACGTGACGAGCGGCCCGGCGCTGGTGAAGAAGGGCGACCTGGCCGGCCTGCTCACCGCGCTCGCCCC
GCGCGACATCCTCTTCATCGACGAGATCCACCGGCTCTCGCCGGCCGTGGAGGAGGCGCTCTACCCGGCCATGGAGGACT
ACCGCTTCGACGTGGTGCTCGGCGCAGGCCTCGGCGCCCAGACCATGGAGATGAAGCTGGAGCGATTCACGCTGGTCGGG
GCCACCACCCGCACCGGCCTGCTCGCGAGCCCGCTCCGCGACCGCTTCCCCATCCAGGAGCGGCTCGAGTACTACGGCCC
GGCCGAGCTGAAGGAGATCGCGGTGCGGGCCGCGCGCAAGCTGGGGCTGCCGGTGGACGAGGACGGCGCCGAGGAGCTGG
CGCGCCGCGCCCGCGGCACCCCGCGCATCGCCATCCGCCTGCTGCAGCGCGCCCGCGACTTCGCGCAGGTGGAGGGGGAT
GGGCGGCTCACGCGCGAGGTGGTGGACCGCACGCTGCGCCGCCTGGAGGTGGACGCCCGCGGCCTCGACGCGATGGACCG
CCGCATTCTGGCGGCGGTCATCGACACGTTCGGCGGCGGGCCGGTGGGCATCGACGCGGTGGCCGCCGCGGTGGGCGAGG
AGTCGGGCACGCTCGAGGACGTGTACGAGCCGTTCCTGGTGCGCGAGGGGTACCTGGCGCGCACGCCGCGCGGGCGGGTG
GCGCTGCCCGCCGCGTACGCGCACCTCGGGCGCGACCGCCCCGGTGGCAAGCAGGGCTCGCTGGTCTGA

Upstream 100 bases:

>100_bases
GGAGGGCGTGGCGGAGGCGCTGCGCGACTCGGCCGAGGGCCGGCCGCTCGACGAGCTGCTGCGCGAGGCGCTGAAGCTGC
TGCGCGGGTAGGGAGCGACC

Downstream 100 bases:

>100_bases
TCGCGGCCCCCGCGGCTACCAGCTCACCCGGCGCGCGCGCCAGGTCGGGCGCCGCCCCATGAGCCGCACCAGCAGCCATC
CCGCCACGAACCCGCCCACG

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MTVKPLRDVTPKPLEGEERLEQSLRPATFDDYVGQVKIVDNVKVYAAAARQRGESLDHVLLSGPPGLGKTSLAHILAREL
GVTLHVTSGPALVKKGDLAGLLTALAPRDILFIDEIHRLSPAVEEALYPAMEDYRFDVVLGAGLGAQTMEMKLERFTLVG
ATTRTGLLASPLRDRFPIQERLEYYGPAELKEIAVRAARKLGLPVDEDGAEELARRARGTPRIAIRLLQRARDFAQVEGD
GRLTREVVDRTLRRLEVDARGLDAMDRRILAAVIDTFGGGPVGIDAVAAAVGEESGTLEDVYEPFLVREGYLARTPRGRV
ALPAAYAHLGRDRPGGKQGSLV

Sequences:

>Translated_342_residues
MTVKPLRDVTPKPLEGEERLEQSLRPATFDDYVGQVKIVDNVKVYAAAARQRGESLDHVLLSGPPGLGKTSLAHILAREL
GVTLHVTSGPALVKKGDLAGLLTALAPRDILFIDEIHRLSPAVEEALYPAMEDYRFDVVLGAGLGAQTMEMKLERFTLVG
ATTRTGLLASPLRDRFPIQERLEYYGPAELKEIAVRAARKLGLPVDEDGAEELARRARGTPRIAIRLLQRARDFAQVEGD
GRLTREVVDRTLRRLEVDARGLDAMDRRILAAVIDTFGGGPVGIDAVAAAVGEESGTLEDVYEPFLVREGYLARTPRGRV
ALPAAYAHLGRDRPGGKQGSLV
>Mature_341_residues
TVKPLRDVTPKPLEGEERLEQSLRPATFDDYVGQVKIVDNVKVYAAAARQRGESLDHVLLSGPPGLGKTSLAHILARELG
VTLHVTSGPALVKKGDLAGLLTALAPRDILFIDEIHRLSPAVEEALYPAMEDYRFDVVLGAGLGAQTMEMKLERFTLVGA
TTRTGLLASPLRDRFPIQERLEYYGPAELKEIAVRAARKLGLPVDEDGAEELARRARGTPRIAIRLLQRARDFAQVEGDG
RLTREVVDRTLRRLEVDARGLDAMDRRILAAVIDTFGGGPVGIDAVAAAVGEESGTLEDVYEPFLVREGYLARTPRGRVA
LPAAYAHLGRDRPGGKQGSLV

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=318, Percent_Identity=55.3459119496855, Blast_Score=360, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_ANAD2 (B8JF05)

Other databases:

- EMBL:   CP001359
- RefSeq:   YP_002491428.1
- ProteinModelPortal:   B8JF05
- SMR:   B8JF05
- GeneID:   7297057
- GenomeReviews:   CP001359_GR
- KEGG:   acp:A2cp1_1011
- HOGENOM:   HBG339960
- ProtClustDB:   PRK00080
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR000641
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00819
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 37192; Mature: 37061

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVKPLRDVTPKPLEGEERLEQSLRPATFDDYVGQVKIVDNVKVYAAAARQRGESLDHVL
CCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHCCCEEEECCHHHHHHHHHHCCCCCCEEE
LSGPPGLGKTSLAHILARELGVTLHVTSGPALVKKGDLAGLLTALAPRDILFIDEIHRLS
ECCCCCCCHHHHHHHHHHHHCCEEEEECCCCEEECCHHHHHHHHHCCCCCHHHHHHHHHC
PAVEEALYPAMEDYRFDVVLGAGLGAQTMEMKLERFTLVGATTRTGLLASPLRDRFPIQE
HHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHEEECCCHHCCHHHCCHHHCCCHHH
RLEYYGPAELKEIAVRAARKLGLPVDEDGAEELARRARGTPRIAIRLLQRARDFAQVEGD
HHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
GRLTREVVDRTLRRLEVDARGLDAMDRRILAAVIDTFGGGPVGIDAVAAAVGEESGTLED
CHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHH
VYEPFLVREGYLARTPRGRVALPAAYAHLGRDRPGGKQGSLV
HHHHHHHCCCCEEECCCCCEECHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TVKPLRDVTPKPLEGEERLEQSLRPATFDDYVGQVKIVDNVKVYAAAARQRGESLDHVL
CCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHCCCEEEECCHHHHHHHHHHCCCCCCEEE
LSGPPGLGKTSLAHILARELGVTLHVTSGPALVKKGDLAGLLTALAPRDILFIDEIHRLS
ECCCCCCCHHHHHHHHHHHHCCEEEEECCCCEEECCHHHHHHHHHCCCCCHHHHHHHHHC
PAVEEALYPAMEDYRFDVVLGAGLGAQTMEMKLERFTLVGATTRTGLLASPLRDRFPIQE
HHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHEEECCCHHCCHHHCCHHHCCCHHH
RLEYYGPAELKEIAVRAARKLGLPVDEDGAEELARRARGTPRIAIRLLQRARDFAQVEGD
HHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
GRLTREVVDRTLRRLEVDARGLDAMDRRILAAVIDTFGGGPVGIDAVAAAVGEESGTLED
CHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHH
VYEPFLVREGYLARTPRGRVALPAAYAHLGRDRPGGKQGSLV
HHHHHHHCCCCEEECCCCCEECHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA