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The map label for this gene is rmlA1 [C]

Identifier: 220916039

GI number: 220916039

Start: 1045573

End: 1046343

Strand: Direct

Name: rmlA1 [C]

Synonym: A2cp1_0926

Alternate gene names: 220916039

Gene position: 1045573-1046343 (Clockwise)

Preceding gene: 220916038

Following gene: 220916040

Centisome position: 20.79

GC content: 76.01

Gene sequence:

>771_bases
ATGACATGGGGCATCGTGCCGGCCGCGGGCGTGGGGAGCCGGATCCAGCCGCTGGCGTTCTCGAAGGAGCTGCTGCCGGT
GGGGAGCCGCCTGGTGGACGGCAGCGAGCGCCCGCGCGCCGTGTCGGAGTACCTGGTCGAGCGGATGCTCCGCGGCGGCG
CCGACCGGCTGTGCTTCGTCATCTCGCCGGGCAAGTCGGACATCGTCGAGTACTTCGGCGGCGCCGTCGGCGGCGCCCGC
ATCTGCTACGTGGTCCAGCCGCGGCCGGCCGGGCTGTGCGACGCGCTGTTCCGTGCGCTGCCGTTCGTGGCCCCCGGGGA
CGAGGTGCTGGTCGGGCTGCCGGACACGGTCTGGTTCCCCGCGGACGGCTACCGCGCGCTCCCGGGCGGCGGCCTCGCGT
TCCTGTGCTTCCCGGTGGAGCGGCCGGAGCTGTTCGACGCGGTGGTGAGCGGGCCGGACGGCGCCGTGCGCGAGATCGAG
GTGAAGGCCGCGGCGCCGTCCACCGGCTGGGTGTGGGGCGGCTTCAAGCTGACCGGCGCGGTCCTCGCCGAGCTGCACGC
GCTGTTCGTGGAGCGCGGCGAGGTCGACGCGTACGTCGGGACGCTGGTGAACGCCTGGCTCGAGCGCGGCGGCGCGGCGA
AGGCCGTGCGCAGGGGCCGGGCCTACGTGGACGTCGGGACGCTGGACGGGTACCGGCAGGCGCTGCGGCTGCTCCGCGAG
GGGCCGCAGCCCGAGCCGGAGGACGCCGGCGCGGCGCCGGGGATCGGGTGA

Upstream 100 bases:

>100_bases
TGCCCCCGTTGCCGGGAACGGAGGCGCGCGCGGGGATCGACGCCGGCGGGACGCGGGGGGCCACCGCGGCGCTCGACGCG
GCGGCGGAGGGGCTGGCCGG

Downstream 100 bases:

>100_bases
GCGGATGACGCGAGCGGAGCTCGAGGCGCGCGTGCGCGCGCTCTCGCCGTGGTTCCACAACCTCGAGCTGAACGGCGTGC
GCACCGCGCCGGACCACTTC

Product: nucleotidyl transferase

Products: diphosphate; dTDPglucose

Alternate protein names: UTP-Glucose-1-Phosphate Thymidylyltransferase; Nucleotidyltransferase; Glucose-1-Phosphate Thymidylyltransferase

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MTWGIVPAAGVGSRIQPLAFSKELLPVGSRLVDGSERPRAVSEYLVERMLRGGADRLCFVISPGKSDIVEYFGGAVGGAR
ICYVVQPRPAGLCDALFRALPFVAPGDEVLVGLPDTVWFPADGYRALPGGGLAFLCFPVERPELFDAVVSGPDGAVREIE
VKAAAPSTGWVWGGFKLTGAVLAELHALFVERGEVDAYVGTLVNAWLERGGAAKAVRRGRAYVDVGTLDGYRQALRLLRE
GPQPEPEDAGAAPGIG

Sequences:

>Translated_256_residues
MTWGIVPAAGVGSRIQPLAFSKELLPVGSRLVDGSERPRAVSEYLVERMLRGGADRLCFVISPGKSDIVEYFGGAVGGAR
ICYVVQPRPAGLCDALFRALPFVAPGDEVLVGLPDTVWFPADGYRALPGGGLAFLCFPVERPELFDAVVSGPDGAVREIE
VKAAAPSTGWVWGGFKLTGAVLAELHALFVERGEVDAYVGTLVNAWLERGGAAKAVRRGRAYVDVGTLDGYRQALRLLRE
GPQPEPEDAGAAPGIG
>Mature_255_residues
TWGIVPAAGVGSRIQPLAFSKELLPVGSRLVDGSERPRAVSEYLVERMLRGGADRLCFVISPGKSDIVEYFGGAVGGARI
CYVVQPRPAGLCDALFRALPFVAPGDEVLVGLPDTVWFPADGYRALPGGGLAFLCFPVERPELFDAVVSGPDGAVREIEV
KAAAPSTGWVWGGFKLTGAVLAELHALFVERGEVDAYVGTLVNAWLERGGAAKAVRRGRAYVDVGTLDGYRQALRLLREG
PQPEPEDAGAAPGIG

Specific function: Catalyzes The Formation Of Dtdp-Glucose, From Dttp And Glucose 1-Phosphate, As Well As Its Pyrophosphorolysis. [C]

COG id: COG1209

COG function: function code M; dTDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.7.24

Molecular weight: Translated: 27031; Mature: 26900

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTWGIVPAAGVGSRIQPLAFSKELLPVGSRLVDGSERPRAVSEYLVERMLRGGADRLCFV
CCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEE
ISPGKSDIVEYFGGAVGGARICYVVQPRPAGLCDALFRALPFVAPGDEVLVGLPDTVWFP
ECCCHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEEECCCCEEEC
ADGYRALPGGGLAFLCFPVERPELFDAVVSGPDGAVREIEVKAAAPSTGWVWGGFKLTGA
CCCCEECCCCCEEEEEEECCCHHHHHHHHCCCCCCEEEEEEEECCCCCCEEECCHHHHHH
VLAELHALFVERGEVDAYVGTLVNAWLERGGAAKAVRRGRAYVDVGTLDGYRQALRLLRE
HHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEECCCHHHHHHHHHHHC
GPQPEPEDAGAAPGIG
CCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TWGIVPAAGVGSRIQPLAFSKELLPVGSRLVDGSERPRAVSEYLVERMLRGGADRLCFV
CCCCCCCCCCCCCCCCHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEE
ISPGKSDIVEYFGGAVGGARICYVVQPRPAGLCDALFRALPFVAPGDEVLVGLPDTVWFP
ECCCHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEEECCCCEEEC
ADGYRALPGGGLAFLCFPVERPELFDAVVSGPDGAVREIEVKAAAPSTGWVWGGFKLTGA
CCCCEECCCCCEEEEEEECCCHHHHHHHHCCCCCCEEEEEEEECCCCCCEEECCHHHHHH
VLAELHALFVERGEVDAYVGTLVNAWLERGGAAKAVRRGRAYVDVGTLDGYRQALRLLRE
HHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEECCCHHHHHHHHHHHC
GPQPEPEDAGAAPGIG
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dTTP; alpha-D-glucose 1-phosphate

Specific reaction: dTTP + alpha-D-glucose 1-phosphate = diphosphate + dTDP-glucose

General reaction: Nucleotidyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA