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The map label for this gene is prpC [H]

Identifier: 220915886

GI number: 220915886

Start: 865715

End: 866557

Strand: Direct

Name: prpC [H]

Synonym: A2cp1_0770

Alternate gene names: 220915886

Gene position: 865715-866557 (Clockwise)

Preceding gene: 220915885

Following gene: 220915887

Centisome position: 17.21

GC content: 70.82

Gene sequence:

>843_bases
ATGGCAACCGCGTTGACCCCTCAGTCTGCGGAAAGGTACGCTCCGCGCGTGGCGGCCACGCCTGTCCTGACGATCGCTGC
CCACGGCGTCACGGACGTCGGCCAGCGGCGCGATCACAACGAGGACGCGTTCCTGGTCGATCCCGCGCTGGGGCTGTACG
TGGTCGCCGACGGCATGGGCGGCCACGCGGGCGGCGGCACGGCATCCCGGCTCGCGGTCGAGACCATCCAGGAGTCGATC
CGCGCGGCGCGCGACGGCGCGCCGGAGGTGTTCGAGGGGGCGAACGGGGTCGAGGACAGCCGCCTCCCGGACCTGCTCCG
CGACGCGGTCGAGGCGGCCTGCGCGCGGATCTTCCAGACGGCCCAGGACGCTCCCGAGCTCGCCGGGATGGGGACCACCG
TCACCGCGGCGCTCATCGACGGCCGGGTGGCGTTCGTGGCGCACGTGGGCGACAGCCGCTGCTACCTGCTGCGCGAGGGG
CGCATCTACCAGGTCTCCGAGGACCACTCGCTCGTCAACGAGCAGCTCAAGGCCGGCACCATCAGCGCCGACGAGGCGAA
GCACAGCCGCTTCAAGAACATCATCACTCGATCGGTGGGGTTCGAGGCGCAGGTCCAGGTCGATCTCATGGGCCTCGAGC
TCGAGGACGGCGACGGGCTCGTGATCTGCTGCGACGGCCTGTCCAACCTGGTGGACGACGACGAGATCCTCCAGATCGTG
GACGAATGCCCCATCGACGCGTCGCCGGCGCGCCTGGTCGAGCTCGCGAACGATCGCGGCGGCGACGACAACATCACCGT
GATCGTGATCCGGGCGGGCCGCGAGCCGATCCTGGCCGGCTGA

Upstream 100 bases:

>100_bases
TGAGCCGCCCGCGCGGCCGACCGGGGGATCCTGGGACGCCGCGGGGTCGCACCGGGCCGTCGAGGGGTCACGAACGCGGA
CCGCGGCGTTCGGCGAGACG

Downstream 100 bases:

>100_bases
CGCCTGCCCGCCCGCTCGCGCAGTGCGGGTCCGGGCTGGGGTAAGGTGGGCAAAACCCTTTCTTGACAGGCAACTTCGGG
CTCTGTTACCGGTCTGCCTC

Product: protein serine/threonine phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MATALTPQSAERYAPRVAATPVLTIAAHGVTDVGQRRDHNEDAFLVDPALGLYVVADGMGGHAGGGTASRLAVETIQESI
RAARDGAPEVFEGANGVEDSRLPDLLRDAVEAACARIFQTAQDAPELAGMGTTVTAALIDGRVAFVAHVGDSRCYLLREG
RIYQVSEDHSLVNEQLKAGTISADEAKHSRFKNIITRSVGFEAQVQVDLMGLELEDGDGLVICCDGLSNLVDDDEILQIV
DECPIDASPARLVELANDRGGDDNITVIVIRAGREPILAG

Sequences:

>Translated_280_residues
MATALTPQSAERYAPRVAATPVLTIAAHGVTDVGQRRDHNEDAFLVDPALGLYVVADGMGGHAGGGTASRLAVETIQESI
RAARDGAPEVFEGANGVEDSRLPDLLRDAVEAACARIFQTAQDAPELAGMGTTVTAALIDGRVAFVAHVGDSRCYLLREG
RIYQVSEDHSLVNEQLKAGTISADEAKHSRFKNIITRSVGFEAQVQVDLMGLELEDGDGLVICCDGLSNLVDDDEILQIV
DECPIDASPARLVELANDRGGDDNITVIVIRAGREPILAG
>Mature_279_residues
ATALTPQSAERYAPRVAATPVLTIAAHGVTDVGQRRDHNEDAFLVDPALGLYVVADGMGGHAGGGTASRLAVETIQESIR
AARDGAPEVFEGANGVEDSRLPDLLRDAVEAACARIFQTAQDAPELAGMGTTVTAALIDGRVAFVAHVGDSRCYLLREGR
IYQVSEDHSLVNEQLKAGTISADEAKHSRFKNIITRSVGFEAQVQVDLMGLELEDGDGLVICCDGLSNLVDDDEILQIVD
ECPIDASPARLVELANDRGGDDNITVIVIRAGREPILAG

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 29583; Mature: 29452

Theoretical pI: Translated: 4.23; Mature: 4.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATALTPQSAERYAPRVAATPVLTIAAHGVTDVGQRRDHNEDAFLVDPALGLYVVADGMG
CCCCCCCCCHHHHCCCHHCCCEEEEEECCCHHHHHCCCCCCCEEEECCCCEEEEEEECCC
GHAGGGTASRLAVETIQESIRAARDGAPEVFEGANGVEDSRLPDLLRDAVEAACARIFQT
CCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AQDAPELAGMGTTVTAALIDGRVAFVAHVGDSRCYLLREGRIYQVSEDHSLVNEQLKAGT
HHCCHHHHCCCCHHHHHHHCCCEEEEEEECCCEEEEEECCEEEEECCCHHHHHHHHHCCC
ISADEAKHSRFKNIITRSVGFEAQVQVDLMGLELEDGDGLVICCDGLSNLVDDDEILQIV
CCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEECCCCEEEEECCHHHHCCHHHHHHHH
DECPIDASPARLVELANDRGGDDNITVIVIRAGREPILAG
HHCCCCCCHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCC
>Mature Secondary Structure 
ATALTPQSAERYAPRVAATPVLTIAAHGVTDVGQRRDHNEDAFLVDPALGLYVVADGMG
CCCCCCCCHHHHCCCHHCCCEEEEEECCCHHHHHCCCCCCCEEEECCCCEEEEEEECCC
GHAGGGTASRLAVETIQESIRAARDGAPEVFEGANGVEDSRLPDLLRDAVEAACARIFQT
CCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AQDAPELAGMGTTVTAALIDGRVAFVAHVGDSRCYLLREGRIYQVSEDHSLVNEQLKAGT
HHCCHHHHCCCCHHHHHHHCCCEEEEEEECCCEEEEEECCEEEEECCCHHHHHHHHHCCC
ISADEAKHSRFKNIITRSVGFEAQVQVDLMGLELEDGDGLVICCDGLSNLVDDDEILQIV
CCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEECCCCEEEEECCHHHHCCHHHHHHHH
DECPIDASPARLVELANDRGGDDNITVIVIRAGREPILAG
HHCCCCCCHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]