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The map label for this gene is pgaC [H]

Identifier: 220915822

GI number: 220915822

Start: 789121

End: 790626

Strand: Direct

Name: pgaC [H]

Synonym: A2cp1_0705

Alternate gene names: 220915822

Gene position: 789121-790626 (Clockwise)

Preceding gene: 220915821

Following gene: 220915827

Centisome position: 15.69

GC content: 67.99

Gene sequence:

>1506_bases
ATGACTTCACTCGAGCTCTCGGTCGTCGTCGGGTACGCACTGCTGCTCTGCATCCTCTCGATCTACGGGTCCCATCGCTA
CGCGATGGCGTACCTGTACTACCGGCACAAGTACCGGCTCCCCACGCCGAAGGACCGGTTCGAGCAGCTGCCGCGCGTCA
CCATCCAGCTCCCGATCTTCAACGAGATGTACGTGACGGAGCGGCTCATCGGCGCCGTCGCGAAGATCGACTATCCGCGC
GAGCTCCTCGAGGTGCAGGTCCTCGACGACTCGACCGACGAGACCCAGGGCATCGCCCGCGCCTGCGTGGATCGCGTCCG
GGCCGAGGGGCTCGACATCGTCTACATCCACCGCACCGACCGCAGCGGCTTCAAGGCGGGCGCGCTGGAGAACGGGCTGA
AGACCGCCATGGGCGAGTTCGTGGCGGTCTTCGACGCGGACTTCATCCCGGATCCGCACTTCCTGCGGCGCACCGTGGAC
TTCTTCACCGACCCGAAGGTCGGCATGGTCCAGGCGCGCTGGGGCCACCTGAACCGCGGCTACTCGCTGCTCACCCAGGT
CCAGGCCATCCTGCTCGACGGGCACTTCGTCATCGAGCACACCGCGCGCAACCGCTCCGGCCGCTTCTTCAACTTCAACG
GCACCGCGGGGATCTGGCGGCGCGAGGCCATCGCCTCGGGCGGCGGCTGGCAGCACGACACGCTCACCGAGGACCTGGAC
CTCTCCTACCGCACGCAGATGAAGGGCTGGCAGTTCGTCTACGTGCCGCAGATCGTCACGCCGGCCGAGCTGCCGGTGGA
GATGAACGCGTTCAAGAGCCAGCAGCACCGCTGGGCGAAGGGCTCGATCCAGACCGCGCTCAAGGTCCTGCCGCGGCTGC
TCGACGCGGATCTGCCGCGCGAGGTGAAGCGCGAGGCGGTGATGCACCTCACCGCGAACCTCGCCTACCTGCTGATGATC
CCGCTGGCGATCCTGCTGCCGATCACGGTGGTGGTGCGCGTCTCCCACGGCTGGTACGAGGTGCTGTTCCTCGACATCCC
GTTCTTCGCCGCCGCCACCTTCAGCGTGGTGGCGTTCTACGCGGCCAGCCAGCGCGAGCAGGGCCGCACCACCTGGCAGC
AGATCAAGTACCTGCCCATGGTGATGGCGATCGGCATCGGCCTGTCGGTGAACCAGGCGCGCGCGGTGGTCGAGGCGCTC
ATGGGCTACGAGACCGCCTTCACCCGCACGCCCAAGCACGGCGTCGCCTCGGCGGGCGAGTCGGTGACGCGCAAGCGGTA
CAAGGCGGCGGTCACGTTCCAGCCCATCGTCGAGCTGGCCCTCGCGGCCTACATGACCTACGGCGTGATGTACCTGATCG
AGCGCGAGGTCTACTACTCGCTGCCGTTCCTGCTGCTGTTCCAGGTGGGCTTCGGCTACGTCGGCCTGGCCAGCGTCTAC
GAGGGCCTGCGCGGCCGCGTCGGGCGCTGGGTCCGCGTGCTCTCGCCGCAGCCCTCGCCGGAGTAG

Upstream 100 bases:

>100_bases
CGCGCCAATCCTTCCGGAGACGGAGGGGCGACGCCCTGGCCCGCAGATTGCGATTCGCGGCCCTCTCCGGAGGCGCCCAC
CGGCGCACACACACGTCAAG

Downstream 100 bases:

>100_bases
CGGCCCGCCCGGCGGGTCCGCGAAGCACGACGGGCGTCCTTCGGCAGGCTCAGGAGGAGCGGGCCTTCGATCCGCTCGCC
CTGAGCTCGTCGAAGGGCGG

Product: family 2 glycosyl transferase

Products: NA

Alternate protein names: PGA synthase; Poly-beta-1,6-GlcNAc synthase; Biofilm PGA synthesis protein PgaC; N-acetylglucosaminyltransferase PgaC [H]

Number of amino acids: Translated: 501; Mature: 500

Protein sequence:

>501_residues
MTSLELSVVVGYALLLCILSIYGSHRYAMAYLYYRHKYRLPTPKDRFEQLPRVTIQLPIFNEMYVTERLIGAVAKIDYPR
ELLEVQVLDDSTDETQGIARACVDRVRAEGLDIVYIHRTDRSGFKAGALENGLKTAMGEFVAVFDADFIPDPHFLRRTVD
FFTDPKVGMVQARWGHLNRGYSLLTQVQAILLDGHFVIEHTARNRSGRFFNFNGTAGIWRREAIASGGGWQHDTLTEDLD
LSYRTQMKGWQFVYVPQIVTPAELPVEMNAFKSQQHRWAKGSIQTALKVLPRLLDADLPREVKREAVMHLTANLAYLLMI
PLAILLPITVVVRVSHGWYEVLFLDIPFFAAATFSVVAFYAASQREQGRTTWQQIKYLPMVMAIGIGLSVNQARAVVEAL
MGYETAFTRTPKHGVASAGESVTRKRYKAAVTFQPIVELALAAYMTYGVMYLIEREVYYSLPFLLLFQVGFGYVGLASVY
EGLRGRVGRWVRVLSPQPSPE

Sequences:

>Translated_501_residues
MTSLELSVVVGYALLLCILSIYGSHRYAMAYLYYRHKYRLPTPKDRFEQLPRVTIQLPIFNEMYVTERLIGAVAKIDYPR
ELLEVQVLDDSTDETQGIARACVDRVRAEGLDIVYIHRTDRSGFKAGALENGLKTAMGEFVAVFDADFIPDPHFLRRTVD
FFTDPKVGMVQARWGHLNRGYSLLTQVQAILLDGHFVIEHTARNRSGRFFNFNGTAGIWRREAIASGGGWQHDTLTEDLD
LSYRTQMKGWQFVYVPQIVTPAELPVEMNAFKSQQHRWAKGSIQTALKVLPRLLDADLPREVKREAVMHLTANLAYLLMI
PLAILLPITVVVRVSHGWYEVLFLDIPFFAAATFSVVAFYAASQREQGRTTWQQIKYLPMVMAIGIGLSVNQARAVVEAL
MGYETAFTRTPKHGVASAGESVTRKRYKAAVTFQPIVELALAAYMTYGVMYLIEREVYYSLPFLLLFQVGFGYVGLASVY
EGLRGRVGRWVRVLSPQPSPE
>Mature_500_residues
TSLELSVVVGYALLLCILSIYGSHRYAMAYLYYRHKYRLPTPKDRFEQLPRVTIQLPIFNEMYVTERLIGAVAKIDYPRE
LLEVQVLDDSTDETQGIARACVDRVRAEGLDIVYIHRTDRSGFKAGALENGLKTAMGEFVAVFDADFIPDPHFLRRTVDF
FTDPKVGMVQARWGHLNRGYSLLTQVQAILLDGHFVIEHTARNRSGRFFNFNGTAGIWRREAIASGGGWQHDTLTEDLDL
SYRTQMKGWQFVYVPQIVTPAELPVEMNAFKSQQHRWAKGSIQTALKVLPRLLDADLPREVKREAVMHLTANLAYLLMIP
LAILLPITVVVRVSHGWYEVLFLDIPFFAAATFSVVAFYAASQREQGRTTWQQIKYLPMVMAIGIGLSVNQARAVVEALM
GYETAFTRTPKHGVASAGESVTRKRYKAAVTFQPIVELALAAYMTYGVMYLIEREVYYSLPFLLLFQVGFGYVGLASVYE
GLRGRVGRWVRVLSPQPSPE

Specific function: Probable N-acetylglucosaminyltransferase that catalyzes the polymerization of single monomer units of UDP-N- acetylglucosamine to produce the linear homopolymer poly-beta-1,6- N-acetyl-D-glucosamine (PGA), a biofilm adhesin polysaccharide [H]

COG id: COG1215

COG function: function code M; Glycosyltransferases, probably involved in cell wall biogenesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family [H]

Homologues:

Organism=Escherichia coli, GI1787259, Length=258, Percent_Identity=29.8449612403101, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI87082284, Length=325, Percent_Identity=28.9230769230769, Blast_Score=99, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: NA

Molecular weight: Translated: 56728; Mature: 56596

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLELSVVVGYALLLCILSIYGSHRYAMAYLYYRHKYRLPTPKDRFEQLPRVTIQLPIF
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEECCCCCHHHHHHCCCEEEEECCC
NEMYVTERLIGAVAKIDYPRELLEVQVLDDSTDETQGIARACVDRVRAEGLDIVYIHRTD
CHHHHHHHHHHHHHHCCCCHHHHEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEECC
RSGFKAGALENGLKTAMGEFVAVFDADFIPDPHFLRRTVDFFTDPKVGMVQARWGHLNRG
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCH
YSLLTQVQAILLDGHFVIEHTARNRSGRFFNFNGTAGIWRREAIASGGGWQHDTLTEDLD
HHHHHHHHHHHHCCCEEEEECCCCCCCCEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCC
LSYRTQMKGWQFVYVPQIVTPAELPVEMNAFKSQQHRWAKGSIQTALKVLPRLLDADLPR
CCHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
EVKREAVMHLTANLAYLLMIPLAILLPITVVVRVSHGWYEVLFLDIPFFAAATFSVVAFY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEEEECCHHHHHHHHHHHHH
AASQREQGRTTWQQIKYLPMVMAIGIGLSVNQARAVVEALMGYETAFTRTPKHGVASAGE
HHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHCCCCCCCHHHCCH
SVTRKRYKAAVTFQPIVELALAAYMTYGVMYLIEREVYYSLPFLLLFQVGFGYVGLASVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
EGLRGRVGRWVRVLSPQPSPE
HHHHHHHHHHEEEECCCCCCC
>Mature Secondary Structure 
TSLELSVVVGYALLLCILSIYGSHRYAMAYLYYRHKYRLPTPKDRFEQLPRVTIQLPIF
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEECCCCCHHHHHHCCCEEEEECCC
NEMYVTERLIGAVAKIDYPRELLEVQVLDDSTDETQGIARACVDRVRAEGLDIVYIHRTD
CHHHHHHHHHHHHHHCCCCHHHHEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEECC
RSGFKAGALENGLKTAMGEFVAVFDADFIPDPHFLRRTVDFFTDPKVGMVQARWGHLNRG
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCH
YSLLTQVQAILLDGHFVIEHTARNRSGRFFNFNGTAGIWRREAIASGGGWQHDTLTEDLD
HHHHHHHHHHHHCCCEEEEECCCCCCCCEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCC
LSYRTQMKGWQFVYVPQIVTPAELPVEMNAFKSQQHRWAKGSIQTALKVLPRLLDADLPR
CCHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
EVKREAVMHLTANLAYLLMIPLAILLPITVVVRVSHGWYEVLFLDIPFFAAATFSVVAFY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEEEECCHHHHHHHHHHHHH
AASQREQGRTTWQQIKYLPMVMAIGIGLSVNQARAVVEALMGYETAFTRTPKHGVASAGE
HHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHCCCCCCCHHHCCH
SVTRKRYKAAVTFQPIVELALAAYMTYGVMYLIEREVYYSLPFLLLFQVGFGYVGLASVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
EGLRGRVGRWVRVLSPQPSPE
HHHHHHHHHHEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]