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The map label for this gene is nqo13 [H]

Identifier: 220915562

GI number: 220915562

Start: 502422

End: 504050

Strand: Direct

Name: nqo13 [H]

Synonym: A2cp1_0443

Alternate gene names: 220915562

Gene position: 502422-504050 (Clockwise)

Preceding gene: 220915561

Following gene: 220915563

Centisome position: 9.99

GC content: 69.92

Gene sequence:

>1629_bases
GTGAACCTGCTCACCGTCGTCACCTTCCTCCCGCTCCTGGGCGCGCTCGCGATGGTGCTCGTCCCGCGGGACGAGCCGTC
GCAGCACCGGGCGCTGGCGCTGGTCGCCTCGCTCGTCACCTTCGCGCTGTCGCTGGGGCTCTGGTTCGGGTTCGACGCGA
GCCCGGGCGCGCCCGAGTTCCAGTTCGAGCTCATGGTCCCGTGGATGCCCACCATCGGCATCGGGTTCCACGTCGGCATC
GACGGCGTCGCGCTGCTCCTGTTCATGCTCACCACCGTGCTGATGCCGGTGGTGGTGCTCTCCGCCTGGAAGGCGGTGGG
CGACCGCGTGAAGGAGTTCATGATCGCGCTGCTGGTGCTCGAGAGCGCCATGCTCGGCACGTTCATCGCGCTCGACCTGG
TGCTCTTCTACGTGTTCTGGGAGGCGATGCTCATCCCGATGTACCTGCTCATCGGGATCTGGGGCTCGCAGAACCGCCTC
TACGCGACCGTGAAGTTCTTCGTGTACACGTTCGCGGCCAGCGTGCTGATGCTGCTCGCCATCCTGTACGTGTACTTCCA
CGACGGCGGCACGTTCGACTACGTCGAGGCCCGGCGCGCGCTGGCGGTGACGCCCGGCGCCGCGAGCTGGCTGTTCCTCG
CGTTCGCGCTGGCGTTCGCGGTCAAGGTGCCGATGTTCCCGTTGCACACCTGGCTGCCGGACGCGCACACCGAGGCGCCC
ACCGCCGGCTCGGTGATCCTGGCCGGCGTGCTCCTGAAGATGGGCACGTTCGGCTTCTTCCGCTACGCGCTGCCGCTCTT
CCCGGAGGCGGCGCTGCAGCACCGCAACCTGGTCGCGGTGCTGGCGGTCATCGGGATCATCTACGGCGCGCTCATGTCGC
TCGTGCAGACCGACATGAAGCGGCTGGTGGCCTACTCCTCGGTCTCGCACCTCGGCTTCGTGATGCTGGGCCTGATGGCC
CTCTCCGCCGAGGGGATGACCGGGTCGGTCTACCAGATGCTGAACCACGGCGTGTCCACCGGCGCGCTGTTCCTCCTCGT
CGGCATGCTCTACGAGCGGCGCCACACCCGCCTCATCTCCGAGTACGGCGGCATCGCCAAGCGCGTGCCGGTGATCGCGG
CGGCGTTCGTGATCGTGACGCTCTCCTCGATCGGCCTCCCCGGCACCAACGGGTTCGTGGGCGAGTTCCTGATCCTGTCC
GGCACCTGGCTCTCGCGCCTGGGCGGGTCGGCGGTGTTCGCCACGGTCGCGGCGCTGGGCGTCATCCTGGGCGCGGTCTA
CATGCTGCTGCTGGTGGAGAAGGTCTTCTTCGGGCCGAACCAGAACCCGCAGAACCACCGCCTCCCGGACCTCTCCGTCC
GCGAGGGCTTCGTGCTCGCCCCGATGATCGCGCTGATCGTGGTGATGGGCCTGCTGCCCGGACCGTTCCTGGCGCCGGCC
AAGCCGGCGGTGGACCGCCTCATCCAGCGCTTCCAGGTGGCCGAGGCGCGCCTCGGCAAGGGCCCGCAGGTCGGCACCGC
GGTCCCGGCGGTGATGGTGCGCGCGCCCGCGCCGGCCCCGGCGGCGGAGCCCGCCCCGCTGCCCGCGCCGGCGCCGGTCC
CGCTCCAGCAGCCCGGAGGGAATTACTGA

Upstream 100 bases:

>100_bases
GCTGGCCCAGAACGGCGACGTGCAGCGCTACGCCGCGATCATGGTGGTCGCCGCCGCCGTCATCCTCTGGACCGTGGTCG
GCGCAGGAGGGCGCTAGCTC

Downstream 100 bases:

>100_bases
CATGAGCGGCTTCCCGACCCAGGACTTCGTCGCGCTGGTCCCGGTGGCGATCCTCACGATGGGGGCGCTGGTCCTGCTGA
TGACCGAGGTGTTCCTCACC

Product: proton-translocating NADH-quinone oxidoreductase subunit M

Products: NA

Alternate protein names: NADH dehydrogenase I, chain 13; NDH-1, chain 13 [H]

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MNLLTVVTFLPLLGALAMVLVPRDEPSQHRALALVASLVTFALSLGLWFGFDASPGAPEFQFELMVPWMPTIGIGFHVGI
DGVALLLFMLTTVLMPVVVLSAWKAVGDRVKEFMIALLVLESAMLGTFIALDLVLFYVFWEAMLIPMYLLIGIWGSQNRL
YATVKFFVYTFAASVLMLLAILYVYFHDGGTFDYVEARRALAVTPGAASWLFLAFALAFAVKVPMFPLHTWLPDAHTEAP
TAGSVILAGVLLKMGTFGFFRYALPLFPEAALQHRNLVAVLAVIGIIYGALMSLVQTDMKRLVAYSSVSHLGFVMLGLMA
LSAEGMTGSVYQMLNHGVSTGALFLLVGMLYERRHTRLISEYGGIAKRVPVIAAAFVIVTLSSIGLPGTNGFVGEFLILS
GTWLSRLGGSAVFATVAALGVILGAVYMLLLVEKVFFGPNQNPQNHRLPDLSVREGFVLAPMIALIVVMGLLPGPFLAPA
KPAVDRLIQRFQVAEARLGKGPQVGTAVPAVMVRAPAPAPAAEPAPLPAPAPVPLQQPGGNY

Sequences:

>Translated_542_residues
MNLLTVVTFLPLLGALAMVLVPRDEPSQHRALALVASLVTFALSLGLWFGFDASPGAPEFQFELMVPWMPTIGIGFHVGI
DGVALLLFMLTTVLMPVVVLSAWKAVGDRVKEFMIALLVLESAMLGTFIALDLVLFYVFWEAMLIPMYLLIGIWGSQNRL
YATVKFFVYTFAASVLMLLAILYVYFHDGGTFDYVEARRALAVTPGAASWLFLAFALAFAVKVPMFPLHTWLPDAHTEAP
TAGSVILAGVLLKMGTFGFFRYALPLFPEAALQHRNLVAVLAVIGIIYGALMSLVQTDMKRLVAYSSVSHLGFVMLGLMA
LSAEGMTGSVYQMLNHGVSTGALFLLVGMLYERRHTRLISEYGGIAKRVPVIAAAFVIVTLSSIGLPGTNGFVGEFLILS
GTWLSRLGGSAVFATVAALGVILGAVYMLLLVEKVFFGPNQNPQNHRLPDLSVREGFVLAPMIALIVVMGLLPGPFLAPA
KPAVDRLIQRFQVAEARLGKGPQVGTAVPAVMVRAPAPAPAAEPAPLPAPAPVPLQQPGGNY
>Mature_542_residues
MNLLTVVTFLPLLGALAMVLVPRDEPSQHRALALVASLVTFALSLGLWFGFDASPGAPEFQFELMVPWMPTIGIGFHVGI
DGVALLLFMLTTVLMPVVVLSAWKAVGDRVKEFMIALLVLESAMLGTFIALDLVLFYVFWEAMLIPMYLLIGIWGSQNRL
YATVKFFVYTFAASVLMLLAILYVYFHDGGTFDYVEARRALAVTPGAASWLFLAFALAFAVKVPMFPLHTWLPDAHTEAP
TAGSVILAGVLLKMGTFGFFRYALPLFPEAALQHRNLVAVLAVIGIIYGALMSLVQTDMKRLVAYSSVSHLGFVMLGLMA
LSAEGMTGSVYQMLNHGVSTGALFLLVGMLYERRHTRLISEYGGIAKRVPVIAAAFVIVTLSSIGLPGTNGFVGEFLILS
GTWLSRLGGSAVFATVAALGVILGAVYMLLLVEKVFFGPNQNPQNHRLPDLSVREGFVLAPMIALIVVMGLLPGPFLAPA
KPAVDRLIQRFQVAEARLGKGPQVGTAVPAVMVRAPAPAPAAEPAPLPAPAPVPLQQPGGNY

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1008

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 4 (chain M)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 4 family [H]

Homologues:

Organism=Homo sapiens, GI251831116, Length=373, Percent_Identity=32.4396782841823, Blast_Score=177, Evalue=3e-44,
Organism=Homo sapiens, GI251831117, Length=331, Percent_Identity=24.773413897281, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI1788613, Length=504, Percent_Identity=39.0873015873016, Blast_Score=343, Evalue=2e-95,
Organism=Escherichia coli, GI1788827, Length=305, Percent_Identity=32.4590163934426, Blast_Score=145, Evalue=7e-36,
Organism=Escherichia coli, GI1788614, Length=459, Percent_Identity=25.7080610021786, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1788831, Length=278, Percent_Identity=27.3381294964029, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI145693160, Length=428, Percent_Identity=28.5046728971963, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788829, Length=416, Percent_Identity=27.8846153846154, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI2367154, Length=235, Percent_Identity=31.063829787234, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010227
- InterPro:   IPR001750
- InterPro:   IPR003918
- InterPro:   IPR000260 [H]

Pfam domain/function: PF00361 Oxidored_q1; PF01059 Oxidored_q5_N [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 58168; Mature: 58168

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLLTVVTFLPLLGALAMVLVPRDEPSQHRALALVASLVTFALSLGLWFGFDASPGAPEF
CHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCE
QFELMVPWMPTIGIGFHVGIDGVALLLFMLTTVLMPVVVLSAWKAVGDRVKEFMIALLVL
EEEEEECCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESAMLGTFIALDLVLFYVFWEAMLIPMYLLIGIWGSQNRLYATVKFFVYTFAASVLMLLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ILYVYFHDGGTFDYVEARRALAVTPGAASWLFLAFALAFAVKVPMFPLHTWLPDAHTEAP
HHHHHHCCCCCCHHHHHHHHEEECCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCC
TAGSVILAGVLLKMGTFGFFRYALPLFPEAALQHRNLVAVLAVIGIIYGALMSLVQTDMK
CCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLVAYSSVSHLGFVMLGLMALSAEGMTGSVYQMLNHGVSTGALFLLVGMLYERRHTRLIS
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
EYGGIAKRVPVIAAAFVIVTLSSIGLPGTNGFVGEFLILSGTWLSRLGGSAVFATVAALG
HHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHCCCHHHHHHHHHHH
VILGAVYMLLLVEKVFFGPNQNPQNHRLPDLSVREGFVLAPMIALIVVMGLLPGPFLAPA
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
KPAVDRLIQRFQVAEARLGKGPQVGTAVPAVMVRAPAPAPAAEPAPLPAPAPVPLQQPGG
CHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCC
NY
CC
>Mature Secondary Structure
MNLLTVVTFLPLLGALAMVLVPRDEPSQHRALALVASLVTFALSLGLWFGFDASPGAPEF
CHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCE
QFELMVPWMPTIGIGFHVGIDGVALLLFMLTTVLMPVVVLSAWKAVGDRVKEFMIALLVL
EEEEEECCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESAMLGTFIALDLVLFYVFWEAMLIPMYLLIGIWGSQNRLYATVKFFVYTFAASVLMLLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ILYVYFHDGGTFDYVEARRALAVTPGAASWLFLAFALAFAVKVPMFPLHTWLPDAHTEAP
HHHHHHCCCCCCHHHHHHHHEEECCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCC
TAGSVILAGVLLKMGTFGFFRYALPLFPEAALQHRNLVAVLAVIGIIYGALMSLVQTDMK
CCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLVAYSSVSHLGFVMLGLMALSAEGMTGSVYQMLNHGVSTGALFLLVGMLYERRHTRLIS
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
EYGGIAKRVPVIAAAFVIVTLSSIGLPGTNGFVGEFLILSGTWLSRLGGSAVFATVAALG
HHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHCCCHHHHHHHHHHH
VILGAVYMLLLVEKVFFGPNQNPQNHRLPDLSVREGFVLAPMIALIVVMGLLPGPFLAPA
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
KPAVDRLIQRFQVAEARLGKGPQVGTAVPAVMVRAPAPAPAAEPAPLPAPAPVPLQQPGG
CHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCC
NY
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8422400 [H]