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The map label for this gene is gpsA

Identifier: 220915544

GI number: 220915544

Start: 478668

End: 479666

Strand: Direct

Name: gpsA

Synonym: A2cp1_0425

Alternate gene names: 220915544

Gene position: 478668-479666 (Clockwise)

Preceding gene: 220915543

Following gene: 220915545

Centisome position: 9.52

GC content: 72.77

Gene sequence:

>999_bases
ATGCGCGCCACCGTCCTGGGCGCCGGTTCCTGGGGAACCGCGCTCGCCTCGCTCCTCGCCGGCAAGGGCTACACCGTCAC
CTCGTGGGACAAGGACGCCGCCGTCCTCGACGACATCGCGCGCAACCACCGCAACGAGCGCTACCTGCCCGGCCTGCAGC
TCCCGCCGACGCTGCACGCCAGCGGCGAGGTCGCGAAGGCGCTGGAGGGCGCAGAGCTGGTGGTCCTCGCCGTGCCCTCG
CACGCCGTCCGCCCGGTGGTGATCGAGGCGAAGCGCCACGTGCACGCCGGGACGCCCATCGTCTGCGTCGCGAAGGGCAT
CGAGCTCGACACGCTCATGACCATGACCGAGGTCATCGAGGACGTGCTGCCGGTCCCGCTCCATCCCTACCTGGCGGTCC
TCTCCGGCCCGTCCTTCGCGAAGGAGGTCGCGAAGGGCCTGCCCACCGCGGTCACGGTGGCCGCGCGCTGGGAGCGGATC
GCGAAGCAGGTGCAGGACGCCTTCCACACCAAGACCTTCCGCCCGTACACCTCCGGTGACGTGGTGGGCTGCGAGATCGG
CGGCTGCGTGAAGAACGTGGTCGCCATCGCGGCCGGCATCTCCGACGGCATGGGCTTCGGCGCGAACGCCATGGCGGCGC
TCGTCACCCGCGGGCTCGCCGAGATCACGCGGCTCGCGGTGCGCAAGGGCGCGAACCCGCTCACGCTGTCCGGCCTGGCC
GGCCTGGGCGACCTGGTGCTGACCTGCTCGTCGGACCTGTCGCGCAACCGCACCGTCGGGCGCGGGCTCGCGGCGGGCAA
GACCGCCGACGCGATCCAGCGCGAGCTCGGGCAGGTGGCGGAGGGCGTGCGCAACGCGCGCAGCGCGCGGGAGCTGGCGA
AGCGGCTGGGCGTGGAGATGCCCATCACCGAGGCGATCTACCGGGTGCTGTACGAGGGGCTCGCGCCGCGCGAGGCGGTG
ACGGCGCTCATGATGCGCGAGACCAAGCCCGAGCTGTGA

Upstream 100 bases:

>100_bases
GGGACGCCCCGGCGTTCCGCCCCATCACGGCCCGCCCCGCAGAATCAAGACCGTTTCGCGGACCGCTCCTGGCTAGGATG
GCCACAAAGGAGAACCCATC

Downstream 100 bases:

>100_bases
CCGGCGCCGGGCGCGCACGGGGACCGCGCCGCCGTGGCCCCGCGCGCACCGCGGGTGCGGTCCCGCACCGGCCCCGTGCG
GATCGGCCCGGGGCGAAGTA

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MRATVLGAGSWGTALASLLAGKGYTVTSWDKDAAVLDDIARNHRNERYLPGLQLPPTLHASGEVAKALEGAELVVLAVPS
HAVRPVVIEAKRHVHAGTPIVCVAKGIELDTLMTMTEVIEDVLPVPLHPYLAVLSGPSFAKEVAKGLPTAVTVAARWERI
AKQVQDAFHTKTFRPYTSGDVVGCEIGGCVKNVVAIAAGISDGMGFGANAMAALVTRGLAEITRLAVRKGANPLTLSGLA
GLGDLVLTCSSDLSRNRTVGRGLAAGKTADAIQRELGQVAEGVRNARSARELAKRLGVEMPITEAIYRVLYEGLAPREAV
TALMMRETKPEL

Sequences:

>Translated_332_residues
MRATVLGAGSWGTALASLLAGKGYTVTSWDKDAAVLDDIARNHRNERYLPGLQLPPTLHASGEVAKALEGAELVVLAVPS
HAVRPVVIEAKRHVHAGTPIVCVAKGIELDTLMTMTEVIEDVLPVPLHPYLAVLSGPSFAKEVAKGLPTAVTVAARWERI
AKQVQDAFHTKTFRPYTSGDVVGCEIGGCVKNVVAIAAGISDGMGFGANAMAALVTRGLAEITRLAVRKGANPLTLSGLA
GLGDLVLTCSSDLSRNRTVGRGLAAGKTADAIQRELGQVAEGVRNARSARELAKRLGVEMPITEAIYRVLYEGLAPREAV
TALMMRETKPEL
>Mature_332_residues
MRATVLGAGSWGTALASLLAGKGYTVTSWDKDAAVLDDIARNHRNERYLPGLQLPPTLHASGEVAKALEGAELVVLAVPS
HAVRPVVIEAKRHVHAGTPIVCVAKGIELDTLMTMTEVIEDVLPVPLHPYLAVLSGPSFAKEVAKGLPTAVTVAARWERI
AKQVQDAFHTKTFRPYTSGDVVGCEIGGCVKNVVAIAAGISDGMGFGANAMAALVTRGLAEITRLAVRKGANPLTLSGLA
GLGDLVLTCSSDLSRNRTVGRGLAAGKTADAIQRELGQVAEGVRNARSARELAKRLGVEMPITEAIYRVLYEGLAPREAV
TALMMRETKPEL

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI33695088, Length=352, Percent_Identity=29.2613636363636, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI24307999, Length=351, Percent_Identity=27.0655270655271, Blast_Score=126, Evalue=3e-29,
Organism=Escherichia coli, GI1790037, Length=331, Percent_Identity=46.2235649546828, Blast_Score=280, Evalue=1e-76,
Organism=Caenorhabditis elegans, GI32564403, Length=357, Percent_Identity=29.1316526610644, Blast_Score=133, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI193210136, Length=357, Percent_Identity=29.1316526610644, Blast_Score=133, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI32564399, Length=348, Percent_Identity=29.3103448275862, Blast_Score=132, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17507425, Length=339, Percent_Identity=26.2536873156342, Blast_Score=117, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI193210134, Length=345, Percent_Identity=27.8260869565217, Blast_Score=101, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6324513, Length=346, Percent_Identity=30.635838150289, Blast_Score=136, Evalue=5e-33,
Organism=Saccharomyces cerevisiae, GI6320181, Length=341, Percent_Identity=28.7390029325513, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI17136200, Length=345, Percent_Identity=25.2173913043478, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI17136204, Length=345, Percent_Identity=25.2173913043478, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI17136202, Length=345, Percent_Identity=25.2173913043478, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI22026922, Length=331, Percent_Identity=24.4712990936556, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI45551945, Length=345, Percent_Identity=24.3478260869565, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI281362270, Length=291, Percent_Identity=25.085910652921, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24648969, Length=304, Percent_Identity=25.3289473684211, Blast_Score=81, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_ANAD2 (B8JAX1)

Other databases:

- EMBL:   CP001359
- RefSeq:   YP_002490848.1
- ProteinModelPortal:   B8JAX1
- SMR:   B8JAX1
- GeneID:   7299308
- GenomeReviews:   CP001359_GR
- KEGG:   acp:A2cp1_0425
- HOGENOM:   HBG586392
- ProtClustDB:   PRK00094
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 34949; Mature: 34949

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 191-191 BINDING 105-105 BINDING 105-105 BINDING 140-140 BINDING 255-255 BINDING 281-281

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRATVLGAGSWGTALASLLAGKGYTVTSWDKDAAVLDDIARNHRNERYLPGLQLPPTLHA
CCEEEEECCCHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
SGEVAKALEGAELVVLAVPSHAVRPVVIEAKRHVHAGTPIVCVAKGIELDTLMTMTEVIE
CCHHHHHHCCCCEEEEECCCCCCCHHEEECHHHHCCCCCEEEEECCCCHHHHHHHHHHHH
DVLPVPLHPYLAVLSGPSFAKEVAKGLPTAVTVAARWERIAKQVQDAFHTKTFRPYTSGD
HHCCCCCHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
VVGCEIGGCVKNVVAIAAGISDGMGFGANAMAALVTRGLAEITRLAVRKGANPLTLSGLA
EEEEEHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHH
GLGDLVLTCSSDLSRNRTVGRGLAAGKTADAIQRELGQVAEGVRNARSARELAKRLGVEM
HHHHHHHHCCCHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PITEAIYRVLYEGLAPREAVTALMMRETKPEL
CHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRATVLGAGSWGTALASLLAGKGYTVTSWDKDAAVLDDIARNHRNERYLPGLQLPPTLHA
CCEEEEECCCHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
SGEVAKALEGAELVVLAVPSHAVRPVVIEAKRHVHAGTPIVCVAKGIELDTLMTMTEVIE
CCHHHHHHCCCCEEEEECCCCCCCHHEEECHHHHCCCCCEEEEECCCCHHHHHHHHHHHH
DVLPVPLHPYLAVLSGPSFAKEVAKGLPTAVTVAARWERIAKQVQDAFHTKTFRPYTSGD
HHCCCCCHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
VVGCEIGGCVKNVVAIAAGISDGMGFGANAMAALVTRGLAEITRLAVRKGANPLTLSGLA
EEEEEHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHH
GLGDLVLTCSSDLSRNRTVGRGLAAGKTADAIQRELGQVAEGVRNARSARELAKRLGVEM
HHHHHHHHCCCHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PITEAIYRVLYEGLAPREAVTALMMRETKPEL
CHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA