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The map label for this gene is zraS [C]

Identifier: 220915440

GI number: 220915440

Start: 356567

End: 358690

Strand: Direct

Name: zraS [C]

Synonym: A2cp1_0319

Alternate gene names: 220915440

Gene position: 356567-358690 (Clockwise)

Preceding gene: 220915439

Following gene: 220915442

Centisome position: 7.09

GC content: 78.39

Gene sequence:

>2124_bases
ATGGCACCCGACGCGTCAGCGCCGCCCGCGGCCCCCGGCCCCGGTGACGCGCCGCGCCCCGGGCGCAGGGCGCCGTGGGG
TGGCGTCGCCGCGGCCGCGGCGGTGCTCCTCCTCGGCGGCGCGGTGCTCCAGCAGCACGAGGTCGCAGAGGGGCGGGGCC
GGCGGCGCGCGGTGCTCGAGCGCGCGGACCTCGCCGCGCGCGCCATCGAGGACGACCTGTCGCGCAGCCTCGCCGCGGCC
CACGCGCTCGCCGCGCTGGTGCGCCACGCCGACGTCGACCGGTTCGAGCAGATCGCCGACGAGCTGCTCTCGCACTACGG
CGGCATCAGCAGCCTGCAGCTCGCGCCCGGCGGCGTGCTCACCCGCATCCACCCGCTCGCCGGAAACGAGGCGGCGCTGG
GCCTCGACCTGCTCGCGGATCCCGAGCATCGCGACTCGGCCGAGCGCACGCTGGAGTCGCGCCAGCTCACCGCCGAGGGG
CCGTTCGAGCTGCGCCAGGGTGGGCAGGGGGTGGTGGGGCGGATCGCGGTGTTCCGCACCGCGCCCGGCGGCGGCGAGGC
GTTCTGGGGCTTCGTGGCGGTGGCGGTGCGGCTGCCCGAGGTGGTGAGCCGGACGCGGGTGGCGGCCCTGTCGGCGGGCG
GGCTCGACTGGGCGCTCCGGCGCGACGGCGCCGCGCGGCCGTTCGCGTCCTCGGGCGGCGCGCTCCCGCGCGACGCGGTC
GCGGTCAAGGTCCGGCTGCCGGGCGAGGCCTGGGAGCTGGACGTGGCGCCGCGCGAGGGCTGGGTGCGCTGGGGCGGGCT
GGTCATGCCGGCGGCGCTGCTCCTGCTGGTGGCGGCGGCGAGCGGGCTGCTCGCGCACCGGCTCCTGCGGCTGCCGGAGG
AGCTCCGGCGCGCGGTGGACGAGCGGACCGCGGCGCTGGCGCTCGCGAACCGGCGGCTCGCGGCCGAGCTGGTGGAGCGG
CAGCGCGCCGAGGAGGCGCGGCAGGCGGCGGAGGCGCAGGCGCGGCACGGGCAGAAGATGGAGGCGGTGGGGCTGCTCGC
CGGCGGGATCGCGCACGACTTCAACAACCTGCTCACCGGGATCCTCGGCTACGCCGAGCTGCTGGGCGAGGCCGGCACCG
CCGCGGACGAGGCGGCCGCCGGGATCCGCCAGGCCGCGCGCCGGGGCGCCGCGCTGACCCGGCAGCTGCTCGGGTTCGCG
CGCCGGGGCAAGTACCAGCAGGTGCCGGTGAACGTCCACGCGCTGGTGCGCGAGGTGTCCGCGCTGCTCGAGCGCACGCT
CGACAAGCGCATCGCCATCCGGCACCGGCTCGCCGCCGGCAGCGCGGTGGTGCGCGGCGACCCCGACCAGCTCCAGCAGG
TCGTGCTCAACCTGGCGGTGAACGCGCGGGACGCGATGCCCTCCGGCGGCACGCTGACGTTCGAGGTCGCCGAGGTGGAG
CTCGACGCGGAGGGCACGCGCGCACGGCCCGGCCTCGCGCCCGGCCCGCACGTGGCGGTCACGGTGGCGGACACCGGCGT
GGGCATCCCCGCGGTGGTGCGCGACCGCGTCTTCGATCCGTTCTTCACCACCAAGCCCGCCGGGCAAGGCACGGGGATGG
GCCTCGCCATGGTGTACGGCATCGTCCAGAACCACGGCGGCTGGGTCGGGTTCGAGAGCGAGGAGGGGAAGGGGGCGCGG
TTCACCGTGCTCCTGCCCGAGGCGCCGGCGCCCGAGCGCGACGAGGCGGTGCCGGCGGGCGCGCCCGAGCACGGCGCCGG
GCGCGTCCTGGTGGCGGACGACGAGCGCGGCGTGCGGGAGACCACCGCGCGGCTCCTGCGCCGCCTCGGCTACGACGCGC
TCCCCGCCGCCTCGATGGAGGAGGCGCTCGAGGTGCAGGGGCGCGGCGCGCTCGACCTCGCGCTGGTGGATCTCGCCATG
CCGGCCGGCGACGGCCCCGAGACGCTGCGCGCCCTGCGCCGCGCCCAGCCCGAGCTCCCCGCCGTGCTCATGACCGGCTA
CGGGCTCGACGCGCGGGTGCGCGAGGCGCTCGAGGGCGGGTTCCGCGGAATCCTGCACAAGCCGTTCAGCCTGGAGGAGC
TCGCCGCCGAGGTGGCGCGCGCCGTTCGTCGGCGCGGCGCCTGA

Upstream 100 bases:

>100_bases
CGCGCGAGGTGGACGCCGCGGCGGACGCGCGGCTCGAGGTGCTCGCCGAGGAGGAGGCGCGGGTGGTGGCGGCCCTGCCG
CTGCTGCCCCGCATCCACTG

Downstream 100 bases:

>100_bases
TGCCGGCCCGCGGGGGCACGCCGGCGGCGACCCCCGAAGCGAGCGTCGCCGGGCGGGCATCCCAGGAGCGGCGGCTGCGC
TGCGGTCCGCCGTCCGTCCG

Product: histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 707; Mature: 706

Protein sequence:

>707_residues
MAPDASAPPAAPGPGDAPRPGRRAPWGGVAAAAAVLLLGGAVLQQHEVAEGRGRRRAVLERADLAARAIEDDLSRSLAAA
HALAALVRHADVDRFEQIADELLSHYGGISSLQLAPGGVLTRIHPLAGNEAALGLDLLADPEHRDSAERTLESRQLTAEG
PFELRQGGQGVVGRIAVFRTAPGGGEAFWGFVAVAVRLPEVVSRTRVAALSAGGLDWALRRDGAARPFASSGGALPRDAV
AVKVRLPGEAWELDVAPREGWVRWGGLVMPAALLLLVAAASGLLAHRLLRLPEELRRAVDERTAALALANRRLAAELVER
QRAEEARQAAEAQARHGQKMEAVGLLAGGIAHDFNNLLTGILGYAELLGEAGTAADEAAAGIRQAARRGAALTRQLLGFA
RRGKYQQVPVNVHALVREVSALLERTLDKRIAIRHRLAAGSAVVRGDPDQLQQVVLNLAVNARDAMPSGGTLTFEVAEVE
LDAEGTRARPGLAPGPHVAVTVADTGVGIPAVVRDRVFDPFFTTKPAGQGTGMGLAMVYGIVQNHGGWVGFESEEGKGAR
FTVLLPEAPAPERDEAVPAGAPEHGAGRVLVADDERGVRETTARLLRRLGYDALPAASMEEALEVQGRGALDLALVDLAM
PAGDGPETLRALRRAQPELPAVLMTGYGLDARVREALEGGFRGILHKPFSLEELAAEVARAVRRRGA

Sequences:

>Translated_707_residues
MAPDASAPPAAPGPGDAPRPGRRAPWGGVAAAAAVLLLGGAVLQQHEVAEGRGRRRAVLERADLAARAIEDDLSRSLAAA
HALAALVRHADVDRFEQIADELLSHYGGISSLQLAPGGVLTRIHPLAGNEAALGLDLLADPEHRDSAERTLESRQLTAEG
PFELRQGGQGVVGRIAVFRTAPGGGEAFWGFVAVAVRLPEVVSRTRVAALSAGGLDWALRRDGAARPFASSGGALPRDAV
AVKVRLPGEAWELDVAPREGWVRWGGLVMPAALLLLVAAASGLLAHRLLRLPEELRRAVDERTAALALANRRLAAELVER
QRAEEARQAAEAQARHGQKMEAVGLLAGGIAHDFNNLLTGILGYAELLGEAGTAADEAAAGIRQAARRGAALTRQLLGFA
RRGKYQQVPVNVHALVREVSALLERTLDKRIAIRHRLAAGSAVVRGDPDQLQQVVLNLAVNARDAMPSGGTLTFEVAEVE
LDAEGTRARPGLAPGPHVAVTVADTGVGIPAVVRDRVFDPFFTTKPAGQGTGMGLAMVYGIVQNHGGWVGFESEEGKGAR
FTVLLPEAPAPERDEAVPAGAPEHGAGRVLVADDERGVRETTARLLRRLGYDALPAASMEEALEVQGRGALDLALVDLAM
PAGDGPETLRALRRAQPELPAVLMTGYGLDARVREALEGGFRGILHKPFSLEELAAEVARAVRRRGA
>Mature_706_residues
APDASAPPAAPGPGDAPRPGRRAPWGGVAAAAAVLLLGGAVLQQHEVAEGRGRRRAVLERADLAARAIEDDLSRSLAAAH
ALAALVRHADVDRFEQIADELLSHYGGISSLQLAPGGVLTRIHPLAGNEAALGLDLLADPEHRDSAERTLESRQLTAEGP
FELRQGGQGVVGRIAVFRTAPGGGEAFWGFVAVAVRLPEVVSRTRVAALSAGGLDWALRRDGAARPFASSGGALPRDAVA
VKVRLPGEAWELDVAPREGWVRWGGLVMPAALLLLVAAASGLLAHRLLRLPEELRRAVDERTAALALANRRLAAELVERQ
RAEEARQAAEAQARHGQKMEAVGLLAGGIAHDFNNLLTGILGYAELLGEAGTAADEAAAGIRQAARRGAALTRQLLGFAR
RGKYQQVPVNVHALVREVSALLERTLDKRIAIRHRLAAGSAVVRGDPDQLQQVVLNLAVNARDAMPSGGTLTFEVAEVEL
DAEGTRARPGLAPGPHVAVTVADTGVGIPAVVRDRVFDPFFTTKPAGQGTGMGLAMVYGIVQNHGGWVGFESEEGKGARF
TVLLPEAPAPERDEAVPAGAPEHGAGRVLVADDERGVRETTARLLRRLGYDALPAASMEEALEVQGRGALDLALVDLAMP
AGDGPETLRALRRAQPELPAVLMTGYGLDARVREALEGGFRGILHKPFSLEELAAEVARAVRRRGA

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=268, Percent_Identity=32.8358208955224, Blast_Score=122, Evalue=8e-29,
Organism=Escherichia coli, GI1788549, Length=249, Percent_Identity=29.3172690763052, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1788713, Length=373, Percent_Identity=24.9329758713137, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1790300, Length=280, Percent_Identity=28.9285714285714, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI48994928, Length=405, Percent_Identity=25.4320987654321, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI145693157, Length=282, Percent_Identity=26.5957446808511, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI87081816, Length=423, Percent_Identity=27.8959810874704, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1786600, Length=235, Percent_Identity=26.8085106382979, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1789149, Length=286, Percent_Identity=25.1748251748252, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1786912, Length=301, Percent_Identity=28.2392026578073, Blast_Score=66, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 74325; Mature: 74193

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: PS50839 CHASE ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPDASAPPAAPGPGDAPRPGRRAPWGGVAAAAAVLLLGGAVLQQHEVAEGRGRRRAVLE
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
RADLAARAIEDDLSRSLAAAHALAALVRHADVDRFEQIADELLSHYGGISSLQLAPGGVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEECCCCHH
TRIHPLAGNEAALGLDLLADPEHRDSAERTLESRQLTAEGPFELRQGGQGVVGRIAVFRT
HEEECCCCCCHHCCCHHCCCCCCCCHHHHHHHHCCCCCCCCHHHHCCCCCCEEEEEEEEE
APGGGEAFWGFVAVAVRLPEVVSRTRVAALSAGGLDWALRRDGAARPFASSGGALPRDAV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCCE
AVKVRLPGEAWELDVAPREGWVRWGGLVMPAALLLLVAAASGLLAHRLLRLPEELRRAVD
EEEEEECCCCEEEECCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
ERTAALALANRRLAAELVERQRAEEARQAAEAQARHGQKMEAVGLLAGGIAHDFNNLLTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
ILGYAELLGEAGTAADEAAAGIRQAARRGAALTRQLLGFARRGKYQQVPVNVHALVREVS
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
ALLERTLDKRIAIRHRLAAGSAVVRGDPDQLQQVVLNLAVNARDAMPSGGTLTFEVAEVE
HHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEE
LDAEGTRARPGLAPGPHVAVTVADTGVGIPAVVRDRVFDPFFTTKPAGQGTGMGLAMVYG
ECCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
IVQNHGGWVGFESEEGKGARFTVLLPEAPAPERDEAVPAGAPEHGAGRVLVADDERGVRE
HHHCCCCEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHH
TTARLLRRLGYDALPAASMEEALEVQGRGALDLALVDLAMPAGDGPETLRALRRAQPELP
HHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCC
AVLMTGYGLDARVREALEGGFRGILHKPFSLEELAAEVARAVRRRGA
EEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
APDASAPPAAPGPGDAPRPGRRAPWGGVAAAAAVLLLGGAVLQQHEVAEGRGRRRAVLE
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
RADLAARAIEDDLSRSLAAAHALAALVRHADVDRFEQIADELLSHYGGISSLQLAPGGVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEECCCCHH
TRIHPLAGNEAALGLDLLADPEHRDSAERTLESRQLTAEGPFELRQGGQGVVGRIAVFRT
HEEECCCCCCHHCCCHHCCCCCCCCHHHHHHHHCCCCCCCCHHHHCCCCCCEEEEEEEEE
APGGGEAFWGFVAVAVRLPEVVSRTRVAALSAGGLDWALRRDGAARPFASSGGALPRDAV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCCE
AVKVRLPGEAWELDVAPREGWVRWGGLVMPAALLLLVAAASGLLAHRLLRLPEELRRAVD
EEEEEECCCCEEEECCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
ERTAALALANRRLAAELVERQRAEEARQAAEAQARHGQKMEAVGLLAGGIAHDFNNLLTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
ILGYAELLGEAGTAADEAAAGIRQAARRGAALTRQLLGFARRGKYQQVPVNVHALVREVS
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
ALLERTLDKRIAIRHRLAAGSAVVRGDPDQLQQVVLNLAVNARDAMPSGGTLTFEVAEVE
HHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEE
LDAEGTRARPGLAPGPHVAVTVADTGVGIPAVVRDRVFDPFFTTKPAGQGTGMGLAMVYG
ECCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
IVQNHGGWVGFESEEGKGARFTVLLPEAPAPERDEAVPAGAPEHGAGRVLVADDERGVRE
HHHCCCCEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHH
TTARLLRRLGYDALPAASMEEALEVQGRGALDLALVDLAMPAGDGPETLRALRRAQPELP
HHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCC
AVLMTGYGLDARVREALEGGFRGILHKPFSLEELAAEVARAVRRRGA
EEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA