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The map label for this gene is aroC

Identifier: 220915329

GI number: 220915329

Start: 227839

End: 228984

Strand: Direct

Name: aroC

Synonym: A2cp1_0208

Alternate gene names: 220915329

Gene position: 227839-228984 (Clockwise)

Preceding gene: 220915328

Following gene: 220915330

Centisome position: 4.53

GC content: 75.48

Gene sequence:

>1146_bases
ATGACACTTCGGTACCTGACCGCCGGCGAGTCGCACGGCCCGGCGCTGGTCGCCATCGCCGAGGGCTTCCCGGCGGGGCT
GGCGGTGGACTTCGAGGCGGTGGACCGGGACCTGCGCCGCCGGCAGAAGGGCTACGGCCGCGGCGGCCGCATGAAGATCG
AGACCGACGCGGCGCAGTTCCTGGCCGGGCTGCGCGGCGGGCTCACCACCGGCGCGCCCATCGCGCTCGCGGTCTGGAAC
AAGGACCACGAGAACTGGAAGGACCTCGTCTCCCCGTACGCCCGCGGCGGCAAGAAGTTCACCCAGGTCCGCCCCGGCCA
TGCCGATCTCGCCGGCGCGCTCAAGTACGGGCTCGACGACGCGCGCGACGTGCTGGAGCGGGCCAGCGCCCGGTCCACCG
CGGTCACGGTGGCGCTCGGCGCGCTCGCGAAGGCGCTGCTCTCGACCCTGGGCGTGGAGGTGTGCTCGCGGGTGGTGGCC
ATCGGCCCGCGCGAGATCCGGCCGGACGCGCCGCCCACCCCGGCGCAGCGCGACGCCATCGAGGCCTCCGACCTGCACGT
GGACGACGAGGCGCTCGCCGCCGAGTGGCGCGCGCTCATCGACGCGGAGAAGGCGCGCGGCGGCTCCATCGGCGGCGCCT
TCGACGTGTACGCCACCGGGCTCCCCATCGGCGTCGGCAGCCACGTGCACCCGGACCGCCGCCTCGACGCGCGCCTGGCT
GGCGCGCTCTGCGGCGTGCAGGCCATCCGCGCCGTGGAGATCGGCGACGGCACGCAGGTGGGCCGCCCCGGCTACGAGTT
CCACGACGCCATCCACCACGACCCGGCCCGCGGCTTCTGGCGAGACACGAACCGCGCCGGCGGGCTGGAGGGCGGCATGA
CCGACGGCATGCCGCTCCGCGTGCGCGCCTACATGAAGCCCATCCCCACCATGCTCCACCCGCTCGCCACCGTGGACCTC
GCCACCCGCGCGGCCACCCAGGCCCGCTACGAGCGGAGCGACGTGTGCGCGGTGCCGGCCGCCGCGGTGGTGGGCGAGGC
GGTGGTGGCCTGGGAGCTCGCGAACGCGCTCCTGGAGAAGTTCGGCGGCGACGCCGTCGAGGACGTGCGCCGGGCGGTGG
AGGCGTATGCCGCTCGGATCCGCTGA

Upstream 100 bases:

>100_bases
TGCTGGTGCGCCAGGGCGCGCTCGCGTTCACGATCTGGACCGGCCAGCCCGCCCCCGAGGCGGACATGGCCCGCGCGCTC
GAGGCGCGCGAGGGAGCACG

Downstream 100 bases:

>100_bases
GACGCTGGCGCTCACCGGGATGATGGGCTCGGGGAAGTCCACCGTGGCCCCGCTGCTGGCGCGCTGGCTGGGCCGGCGGC
TGGTGCGGCTCGACGACGAG

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MTLRYLTAGESHGPALVAIAEGFPAGLAVDFEAVDRDLRRRQKGYGRGGRMKIETDAAQFLAGLRGGLTTGAPIALAVWN
KDHENWKDLVSPYARGGKKFTQVRPGHADLAGALKYGLDDARDVLERASARSTAVTVALGALAKALLSTLGVEVCSRVVA
IGPREIRPDAPPTPAQRDAIEASDLHVDDEALAAEWRALIDAEKARGGSIGGAFDVYATGLPIGVGSHVHPDRRLDARLA
GALCGVQAIRAVEIGDGTQVGRPGYEFHDAIHHDPARGFWRDTNRAGGLEGGMTDGMPLRVRAYMKPIPTMLHPLATVDL
ATRAATQARYERSDVCAVPAAAVVGEAVVAWELANALLEKFGGDAVEDVRRAVEAYAARIR

Sequences:

>Translated_381_residues
MTLRYLTAGESHGPALVAIAEGFPAGLAVDFEAVDRDLRRRQKGYGRGGRMKIETDAAQFLAGLRGGLTTGAPIALAVWN
KDHENWKDLVSPYARGGKKFTQVRPGHADLAGALKYGLDDARDVLERASARSTAVTVALGALAKALLSTLGVEVCSRVVA
IGPREIRPDAPPTPAQRDAIEASDLHVDDEALAAEWRALIDAEKARGGSIGGAFDVYATGLPIGVGSHVHPDRRLDARLA
GALCGVQAIRAVEIGDGTQVGRPGYEFHDAIHHDPARGFWRDTNRAGGLEGGMTDGMPLRVRAYMKPIPTMLHPLATVDL
ATRAATQARYERSDVCAVPAAAVVGEAVVAWELANALLEKFGGDAVEDVRRAVEAYAARIR
>Mature_380_residues
TLRYLTAGESHGPALVAIAEGFPAGLAVDFEAVDRDLRRRQKGYGRGGRMKIETDAAQFLAGLRGGLTTGAPIALAVWNK
DHENWKDLVSPYARGGKKFTQVRPGHADLAGALKYGLDDARDVLERASARSTAVTVALGALAKALLSTLGVEVCSRVVAI
GPREIRPDAPPTPAQRDAIEASDLHVDDEALAAEWRALIDAEKARGGSIGGAFDVYATGLPIGVGSHVHPDRRLDARLAG
ALCGVQAIRAVEIGDGTQVGRPGYEFHDAIHHDPARGFWRDTNRAGGLEGGMTDGMPLRVRAYMKPIPTMLHPLATVDLA
TRAATQARYERSDVCAVPAAAVVGEAVVAWELANALLEKFGGDAVEDVRRAVEAYAARIR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=360, Percent_Identity=33.6111111111111, Blast_Score=128, Evalue=6e-31,
Organism=Saccharomyces cerevisiae, GI6321290, Length=369, Percent_Identity=28.9972899728997, Blast_Score=120, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_ANAD2 (B8J8W9)

Other databases:

- EMBL:   CP001359
- RefSeq:   YP_002490633.1
- ProteinModelPortal:   B8J8W9
- SMR:   B8J8W9
- GeneID:   7298443
- GenomeReviews:   CP001359_GR
- KEGG:   acp:A2cp1_0208
- HOGENOM:   HBG292336
- ProtClustDB:   PRK05382
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 40440; Mature: 40309

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRYLTAGESHGPALVAIAEGFPAGLAVDFEAVDRDLRRRQKGYGRGGRMKIETDAAQF
CEEEEEECCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHHHHHCCCCCCCEEEEHHHHHH
LAGLRGGLTTGAPIALAVWNKDHENWKDLVSPYARGGKKFTQVRPGHADLAGALKYGLDD
HHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEHHCCCCHHHHHHHHHHCCHH
ARDVLERASARSTAVTVALGALAKALLSTLGVEVCSRVVAIGPREIRPDAPPTPAQRDAI
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCHHHCC
EASDLHVDDEALAAEWRALIDAEKARGGSIGGAFDVYATGLPIGVGSHVHPDRRLDARLA
CHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHH
GALCGVQAIRAVEIGDGTQVGRPGYEFHDAIHHDPARGFWRDTNRAGGLEGGMTDGMPLR
HHHHHHHHHHEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
VRAYMKPIPTMLHPLATVDLATRAATQARYERSDVCAVPAAAVVGEAVVAWELANALLEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHH
FGGDAVEDVRRAVEAYAARIR
HCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLRYLTAGESHGPALVAIAEGFPAGLAVDFEAVDRDLRRRQKGYGRGGRMKIETDAAQF
EEEEEECCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHHHHHCCCCCCCEEEEHHHHHH
LAGLRGGLTTGAPIALAVWNKDHENWKDLVSPYARGGKKFTQVRPGHADLAGALKYGLDD
HHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEHHCCCCHHHHHHHHHHCCHH
ARDVLERASARSTAVTVALGALAKALLSTLGVEVCSRVVAIGPREIRPDAPPTPAQRDAI
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCHHHCC
EASDLHVDDEALAAEWRALIDAEKARGGSIGGAFDVYATGLPIGVGSHVHPDRRLDARLA
CHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHH
GALCGVQAIRAVEIGDGTQVGRPGYEFHDAIHHDPARGFWRDTNRAGGLEGGMTDGMPLR
HHHHHHHHHHEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
VRAYMKPIPTMLHPLATVDLATRAATQARYERSDVCAVPAAAVVGEAVVAWELANALLEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHH
FGGDAVEDVRRAVEAYAARIR
HCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA