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The map label for this gene is dtd [H]

Identifier: 220915321

GI number: 220915321

Start: 221716

End: 222177

Strand: Direct

Name: dtd [H]

Synonym: A2cp1_0200

Alternate gene names: 220915321

Gene position: 221716-222177 (Clockwise)

Preceding gene: 220915318

Following gene: 220915322

Centisome position: 4.41

GC content: 74.46

Gene sequence:

>462_bases
ATGGAAGGACGCGTGCGGGCGGTGATCCAGCGGGTCTCGAGGGCCGAGGTGCGGGTGGGCGGCGCGGCCACCGGCGCGAT
CGGGCGCGGGCTGCTCGTCCTGCTGGGCGTGGCGCGCGACGACGGCGCCCCGGACGCGCGGCTGCTCGCCGACAAGATCG
CGGCCCTGCGGATCTTCGAGGACGCGGCCGGCAAGATGAACCTGGCCGTCGCCGAGGTGGGCGGCGCGGTGCTGGTCGTG
TCGCAGTTCACGCTGCTCGGCGACGCGCGCCGGGGGAACCGGCCCGGCTTCAGCGACGCGGCGCCGCCCGAGGCGGCGAA
CGCGCTCTACGAGTCGGTGTGCGGGATGCTCCGCGAGAAGGGGCTGCGCGTCGAGACCGGGGTGTTCCGCGCCGAGATGG
AGGTCGAGCTGGTGAACGACGGTCCGGTCACCATCCTGCTCGACTCGCGGCGGCTGTTCTAG

Upstream 100 bases:

>100_bases
GGGCCAGGGGCCTGTCACGGAGCGCAACGGGCCCCGGGGAGGCGCCCGCCGCCCGCCGCAGCGCGGCGCTCCGGCGTTGA
AAGCCGGGCCGGCGCGTGCC

Downstream 100 bases:

>100_bases
AGAGGGCGACCGATGAGCGACTGCCTGTTCTGCAGGATCGTGCGGGGCGAGATCCCCGCCAAGCTGGTGCACCAGGACGC
CGACACGGTGGCGTTCGTGG

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MEGRVRAVIQRVSRAEVRVGGAATGAIGRGLLVLLGVARDDGAPDARLLADKIAALRIFEDAAGKMNLAVAEVGGAVLVV
SQFTLLGDARRGNRPGFSDAAPPEAANALYESVCGMLREKGLRVETGVFRAEMEVELVNDGPVTILLDSRRLF

Sequences:

>Translated_153_residues
MEGRVRAVIQRVSRAEVRVGGAATGAIGRGLLVLLGVARDDGAPDARLLADKIAALRIFEDAAGKMNLAVAEVGGAVLVV
SQFTLLGDARRGNRPGFSDAAPPEAANALYESVCGMLREKGLRVETGVFRAEMEVELVNDGPVTILLDSRRLF
>Mature_153_residues
MEGRVRAVIQRVSRAEVRVGGAATGAIGRGLLVLLGVARDDGAPDARLLADKIAALRIFEDAAGKMNLAVAEVGGAVLVV
SQFTLLGDARRGNRPGFSDAAPPEAANALYESVCGMLREKGLRVETGVFRAEMEVELVNDGPVTILLDSRRLF

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine [H]

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family [H]

Homologues:

Organism=Homo sapiens, GI30795227, Length=149, Percent_Identity=44.2953020134228, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI1790320, Length=141, Percent_Identity=54.6099290780142, Blast_Score=149, Evalue=8e-38,
Organism=Caenorhabditis elegans, GI115533292, Length=149, Percent_Identity=41.6107382550336, Blast_Score=109, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6319982, Length=152, Percent_Identity=37.5, Blast_Score=103, Evalue=1e-23,
Organism=Drosophila melanogaster, GI281361569, Length=147, Percent_Identity=40.8163265306122, Blast_Score=97, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003732 [H]

Pfam domain/function: PF02580 Tyr_Deacylase [H]

EC number: NA

Molecular weight: Translated: 16128; Mature: 16128

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGRVRAVIQRVSRAEVRVGGAATGAIGRGLLVLLGVARDDGAPDARLLADKIAALRIFE
CCCHHHHHHHHHHHHHEEECCCCCCHHHCCEEHEEEECCCCCCCHHHHHHHHHHHHHHHH
DAAGKMNLAVAEVGGAVLVVSQFTLLGDARRGNRPGFSDAAPPEAANALYESVCGMLREK
HCCCCEEEEEEHHCCEEEEEEHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
GLRVETGVFRAEMEVELVNDGPVTILLDSRRLF
CCEEECCEEEEEEEEEEECCCCEEEEECCCCCC
>Mature Secondary Structure
MEGRVRAVIQRVSRAEVRVGGAATGAIGRGLLVLLGVARDDGAPDARLLADKIAALRIFE
CCCHHHHHHHHHHHHHEEECCCCCCHHHCCEEHEEEECCCCCCCHHHHHHHHHHHHHHHH
DAAGKMNLAVAEVGGAVLVVSQFTLLGDARRGNRPGFSDAAPPEAANALYESVCGMLREK
HCCCCEEEEEEHHCCEEEEEEHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
GLRVETGVFRAEMEVELVNDGPVTILLDSRRLF
CCEEECCEEEEEEEEEEECCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA