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The map label for this gene is ubiE [C]

Identifier: 220915294

GI number: 220915294

Start: 190253

End: 191233

Strand: Direct

Name: ubiE [C]

Synonym: A2cp1_0173

Alternate gene names: 220915294

Gene position: 190253-191233 (Clockwise)

Preceding gene: 220915293

Following gene: 220915295

Centisome position: 3.78

GC content: 81.14

Gene sequence:

>981_bases
ATGCCTCGACCCGCCCCCGCCCGCCCCGCCGCCCCGAGCCGCCGCCCCGAGGCCCTGCTCGGCTGGATGGAGCTGCTCTC
GGACCCGATCCGGCTCCGCGCGCTGCGCGCGCTCGAGCCGCGCGAGCTGTCGGTGCTGGAGCTCCGCGAGGTGCTGGCGC
TCCCGCAGTCGACCGTGTCGCGCCACCTGAAGACGCTCTCCGACGCGGGCTGGCTCTCCGCCCGGCGCGAGGGCACCCAG
AGCCTGTACGGCTGGGCCGCCGAGCTCGCCCCCGGCGCCCGCAAGCTCTGGCAGCTCGCCCGCGCCGAGAGCGACGGGTG
GGCGGTGGTCCGCGCCGACGCGGTGCGGCTCCGGGCGGTGCGCGCCCGCCGCGACGAGGCGCAGCGCTTCTTCGCCGGCG
CGGCCGGCGCCTGGGACGGGCTGCGCGCCCGCGTGTACGGGCGCGGGGTCGCCGCCGAGGCGCTGCTCGCGCTCGTGCCC
CCGGGCTGGACCGTGGCCGACCTGGGCTGCGGCACCGGCGCGGTCGCCGCCGAGCTGGCGCCCCGCGTGCGGCGGGTGAT
CGCGGTGGACCGCTCCGCCGCCATGCTCCGCGCGGCACGCCGCCGCACCGCCCGCTTCGACAACGTCGAGCTGCACGAGG
CCGACCTCGCGGCGCTGCCGCTCGAGGACGGCGGCTGCGACGCGGCGCTGCTCGTCCTCGTGCTCGCCTACCTGGACGAT
CCCGCCCCGGCGCTGGCCGAGGCGGTGCGGGTGCTGCGCCCGGGCGGGCGCCTCGTGATCCTGGACGCCGCGCGCCACCA
GGACGAGGCGCTCCGGCGCCGCATGGGCCAGGCGCACCCCGGCTTCGAGCCGGACGCGCTCGCCGCGCTCGTCCGCCGGG
CCGGCGCGGCCGGCGTCACCGCGCGGGCGCTGCCGCCCGAGCCGGGCGCGCGAGGCCCGGGGCTGGTCGCCTGCACCGGC
GAGCGGCCCGCCCGGCCCTGA

Upstream 100 bases:

>100_bases
CGGTCCCACCGGGCGGGCCGCCTCGTTTGCGGGGCACCGCGGCCCGGGAGTTGACCACGCCGGCCGGGTGGACTAGCTAT
CCGTCCATCCGGATGCATTG

Downstream 100 bases:

>100_bases
CCGCGCCTCACCACCGACCTTCGACCCTCGTTCCACGCAAAGGAGAAGCACCATGGCCGTGTCCGCCGCGAAGAAGAAGC
CCACCCCGAGCGCCCCTGCG

Product: ArsR family transcriptional regulator

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MPRPAPARPAAPSRRPEALLGWMELLSDPIRLRALRALEPRELSVLELREVLALPQSTVSRHLKTLSDAGWLSARREGTQ
SLYGWAAELAPGARKLWQLARAESDGWAVVRADAVRLRAVRARRDEAQRFFAGAAGAWDGLRARVYGRGVAAEALLALVP
PGWTVADLGCGTGAVAAELAPRVRRVIAVDRSAAMLRAARRRTARFDNVELHEADLAALPLEDGGCDAALLVLVLAYLDD
PAPALAEAVRVLRPGGRLVILDAARHQDEALRRRMGQAHPGFEPDALAALVRRAGAAGVTARALPPEPGARGPGLVACTG
ERPARP

Sequences:

>Translated_326_residues
MPRPAPARPAAPSRRPEALLGWMELLSDPIRLRALRALEPRELSVLELREVLALPQSTVSRHLKTLSDAGWLSARREGTQ
SLYGWAAELAPGARKLWQLARAESDGWAVVRADAVRLRAVRARRDEAQRFFAGAAGAWDGLRARVYGRGVAAEALLALVP
PGWTVADLGCGTGAVAAELAPRVRRVIAVDRSAAMLRAARRRTARFDNVELHEADLAALPLEDGGCDAALLVLVLAYLDD
PAPALAEAVRVLRPGGRLVILDAARHQDEALRRRMGQAHPGFEPDALAALVRRAGAAGVTARALPPEPGARGPGLVACTG
ERPARP
>Mature_325_residues
PRPAPARPAAPSRRPEALLGWMELLSDPIRLRALRALEPRELSVLELREVLALPQSTVSRHLKTLSDAGWLSARREGTQS
LYGWAAELAPGARKLWQLARAESDGWAVVRADAVRLRAVRARRDEAQRFFAGAAGAWDGLRARVYGRGVAAEALLALVPP
GWTVADLGCGTGAVAAELAPRVRRVIAVDRSAAMLRAARRRTARFDNVELHEADLAALPLEDGGCDAALLVLVLAYLDDP
APALAEAVRVLRPGGRLVILDAARHQDEALRRRMGQAHPGFEPDALAALVRRAGAAGVTARALPPEPGARGPGLVACTGE
RPARP

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR005149
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08241 Methyltransf_11; PF03551 PadR [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 34867; Mature: 34735

Theoretical pI: Translated: 11.29; Mature: 11.29

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRPAPARPAAPSRRPEALLGWMELLSDPIRLRALRALEPRELSVLELREVLALPQSTVS
CCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHH
RHLKTLSDAGWLSARREGTQSLYGWAAELAPGARKLWQLARAESDGWAVVRADAVRLRAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCEEEEEHHHHHHHHH
RARRDEAQRFFAGAAGAWDGLRARVYGRGVAAEALLALVPPGWTVADLGCGTGAVAAELA
HHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCEEEECCCCCHHHHHHHH
PRVRRVIAVDRSAAMLRAARRRTARFDNVELHEADLAALPLEDGGCDAALLVLVLAYLDD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEECCCCCCCCHHHHHHHHHHHCC
PAPALAEAVRVLRPGGRLVILDAARHQDEALRRRMGQAHPGFEPDALAALVRRAGAAGVT
CCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCE
ARALPPEPGARGPGLVACTGERPARP
ECCCCCCCCCCCCCEEEECCCCCCCC
>Mature Secondary Structure 
PRPAPARPAAPSRRPEALLGWMELLSDPIRLRALRALEPRELSVLELREVLALPQSTVS
CCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHH
RHLKTLSDAGWLSARREGTQSLYGWAAELAPGARKLWQLARAESDGWAVVRADAVRLRAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCEEEEEHHHHHHHHH
RARRDEAQRFFAGAAGAWDGLRARVYGRGVAAEALLALVPPGWTVADLGCGTGAVAAELA
HHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCEEEECCCCCHHHHHHHH
PRVRRVIAVDRSAAMLRAARRRTARFDNVELHEADLAALPLEDGGCDAALLVLVLAYLDD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEECCCCCCCCHHHHHHHHHHHCC
PAPALAEAVRVLRPGGRLVILDAARHQDEALRRRMGQAHPGFEPDALAALVRRAGAAGVT
CCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCE
ARALPPEPGARGPGLVACTGERPARP
ECCCCCCCCCCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2155856 [H]