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The map label for this gene is hprK [H]

Identifier: 220915285

GI number: 220915285

Start: 182198

End: 183163

Strand: Direct

Name: hprK [H]

Synonym: A2cp1_0164

Alternate gene names: 220915285

Gene position: 182198-183163 (Clockwise)

Preceding gene: 220915282

Following gene: 220915286

Centisome position: 3.62

GC content: 67.81

Gene sequence:

>966_bases
ATGGATGCGATCCGCGTCGGGGCGCTCCTCGACGACACCAAGTTCGATCTGCGGCTCACGCTCGTCGCGGGCAAGCAGGG
CCTGTCGCGCCGGATCAGCTCCTCGCGCATCCAGAAGCCCGGGCTGGTGCTCGCCGGCTTCACCGAGTACCTGCACAAGG
AGCGCGTGCAGGTGTTCGGGAACACCGAGATGAGCTACCTCGCCACCCTGCCGCGCGAGCGCTCGGTCGAGGTGCTGCGC
AGCTTCTTCGGCCAGGACGTCTCCTGCCTGGTGGTGACGAAGGGGCTGCAGCCGCCGCCCGAGATGATGGCCGCGGCGGA
CGAGGCGGGGGTGCCGCTGCTCCGCACCAGCCACCTCTCCTCCAACTTCATCGAGTCGGTGCAGAACTGCCTGGAGGACG
TGCTCACCGCGCAGACCTCCATGCACGGCGTGCTGCTCGACGTGTTCGGCGTCGGGATCCTGCTGCTCGGCAAGTCCGGC
ATCGGCAAGAGCGAGATCGCGCTCGACCTCATCATGCGCGGCCACCGCCTGGTGGCCGACGACATCGTGGACGTGAAGCG
CAAGACGCCGGAGTCGGTGTTCGGCGCGGGCTCGGAGATCATCAAGCACCACATGGAGATCCGGGGCCTCGGCATCATCA
ACATCAAGGACCTGTTCGGCGTCGCCGCCATCCGCGAGCGGAAGAAGATCGAGATCGTGCTCGAGCTGGTCGAGTGGGAT
CCGAACGTGGAGTACGACCGGCTCGGCGTCGAGGAGCGCAAGTTCCGCATCCTCGACGTGGAGATCCCGATGCTGGTCGT
CCCGGTCCGGCCGGGCCGCAACATGACCACCATCGTGGAGGTGGCCGCGCGCAACCACCTCCTCAAGCTCCAGGGGCACC
ACTCCGCCCGCGAGTTCCAGGAGCGACTGAACCGCGCCATCGCGCTCGCGCCGGGCGGGCGCGTCGGGGAGATCGACGTC
GAATGA

Upstream 100 bases:

>100_bases
AGCCCTCGCCCCCGCCGCCACGGGCGCGCCCGGCCCCGGCCCCGCCGGCGCGCGCCGAAGGTGGCGGGCCCGGGTTTCGC
CGGGTTAGACTCGGCACCCC

Downstream 100 bases:

>100_bases
CCGCCACGGTGAGCCACGCCGGGCCGCAGGTGGTGATCCTCACCGGCGTGTCCGGCTCGGGGAAGTCCACCGCGCTGCGC
GCGCTGGAGGACGCCGGCTT

Product: HPr kinase/phosphorylase

Products: NA

Alternate protein names: HPrK/P; HPr(Ser) kinase/phosphorylase [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MDAIRVGALLDDTKFDLRLTLVAGKQGLSRRISSSRIQKPGLVLAGFTEYLHKERVQVFGNTEMSYLATLPRERSVEVLR
SFFGQDVSCLVVTKGLQPPPEMMAAADEAGVPLLRTSHLSSNFIESVQNCLEDVLTAQTSMHGVLLDVFGVGILLLGKSG
IGKSEIALDLIMRGHRLVADDIVDVKRKTPESVFGAGSEIIKHHMEIRGLGIINIKDLFGVAAIRERKKIEIVLELVEWD
PNVEYDRLGVEERKFRILDVEIPMLVVPVRPGRNMTTIVEVAARNHLLKLQGHHSAREFQERLNRAIALAPGGRVGEIDV
E

Sequences:

>Translated_321_residues
MDAIRVGALLDDTKFDLRLTLVAGKQGLSRRISSSRIQKPGLVLAGFTEYLHKERVQVFGNTEMSYLATLPRERSVEVLR
SFFGQDVSCLVVTKGLQPPPEMMAAADEAGVPLLRTSHLSSNFIESVQNCLEDVLTAQTSMHGVLLDVFGVGILLLGKSG
IGKSEIALDLIMRGHRLVADDIVDVKRKTPESVFGAGSEIIKHHMEIRGLGIINIKDLFGVAAIRERKKIEIVLELVEWD
PNVEYDRLGVEERKFRILDVEIPMLVVPVRPGRNMTTIVEVAARNHLLKLQGHHSAREFQERLNRAIALAPGGRVGEIDV
E
>Mature_321_residues
MDAIRVGALLDDTKFDLRLTLVAGKQGLSRRISSSRIQKPGLVLAGFTEYLHKERVQVFGNTEMSYLATLPRERSVEVLR
SFFGQDVSCLVVTKGLQPPPEMMAAADEAGVPLLRTSHLSSNFIESVQNCLEDVLTAQTSMHGVLLDVFGVGILLLGKSG
IGKSEIALDLIMRGHRLVADDIVDVKRKTPESVFGAGSEIIKHHMEIRGLGIINIKDLFGVAAIRERKKIEIVLELVEWD
PNVEYDRLGVEERKFRILDVEIPMLVVPVRPGRNMTTIVEVAARNHLLKLQGHHSAREFQERLNRAIALAPGGRVGEIDV
E

Specific function: Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-pr

COG id: COG1493

COG function: function code T; Serine kinase of the HPr protein, regulates carbohydrate metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPrK/P family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003755
- InterPro:   IPR011104
- InterPro:   IPR011126 [H]

Pfam domain/function: PF07475 Hpr_kinase_C; PF02603 Hpr_kinase_N [H]

EC number: NA

Molecular weight: Translated: 35564; Mature: 35564

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAIRVGALLDDTKFDLRLTLVAGKQGLSRRISSSRIQKPGLVLAGFTEYLHKERVQVFG
CCCEEECEEECCCCEEEEEEEEECCHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCC
NTEMSYLATLPRERSVEVLRSFFGQDVSCLVVTKGLQPPPEMMAAADEAGVPLLRTSHLS
CCCHHHHHHCCCCCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHCCCCCCCCEEEHHHHH
SNFIESVQNCLEDVLTAQTSMHGVLLDVFGVGILLLGKSGIGKSEIALDLIMRGHRLVAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHCCCCHHHH
DIVDVKRKTPESVFGAGSEIIKHHMEIRGLGIINIKDLFGVAAIRERKKIEIVLELVEWD
HHHHHHHCCCHHHHCCCHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHEEEEECCC
PNVEYDRLGVEERKFRILDVEIPMLVVPVRPGRNMTTIVEVAARNHLLKLQGHHSAREFQ
CCCCHHHCCCCCCCEEEEEEECCEEEEEECCCCCHHHHHHHHHHCCEEEECCCCCHHHHH
ERLNRAIALAPGGRVGEIDVE
HHHHHEEEECCCCCEECEECC
>Mature Secondary Structure
MDAIRVGALLDDTKFDLRLTLVAGKQGLSRRISSSRIQKPGLVLAGFTEYLHKERVQVFG
CCCEEECEEECCCCEEEEEEEEECCHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCC
NTEMSYLATLPRERSVEVLRSFFGQDVSCLVVTKGLQPPPEMMAAADEAGVPLLRTSHLS
CCCHHHHHHCCCCCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHCCCCCCCCEEEHHHHH
SNFIESVQNCLEDVLTAQTSMHGVLLDVFGVGILLLGKSGIGKSEIALDLIMRGHRLVAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHCCCCHHHH
DIVDVKRKTPESVFGAGSEIIKHHMEIRGLGIINIKDLFGVAAIRERKKIEIVLELVEWD
HHHHHHHCCCHHHHCCCHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHEEEEECCC
PNVEYDRLGVEERKFRILDVEIPMLVVPVRPGRNMTTIVEVAARNHLLKLQGHHSAREFQ
CCCCHHHCCCCCCCEEEEEEECCEEEEEECCCCCHHHHHHHHHHCCEEEECCCCCHHHHH
ERLNRAIALAPGGRVGEIDVE
HHHHHEEEECCCCCEECEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA