Click here to switch to the map view.

The map label for this gene is fabH [H]

Identifier: 220915128

GI number: 220915128

Start: 7060

End: 8055

Strand: Direct

Name: fabH [H]

Synonym: A2cp1_0005

Alternate gene names: 220915128

Gene position: 7060-8055 (Clockwise)

Preceding gene: 220915127

Following gene: 220915129

Centisome position: 0.14

GC content: 70.38

Gene sequence:

>996_bases
ATGCCCCGCGCCGCCATCGTCGCCCTCGGCACGCACGTCCCCGACCGCGTGGTCACGAACGAAGAGCTCACGAAGCACAT
GGAGACCACCGACGCCTGGATCCAGGAGCGCACCGGGATCCAGGAGCGCCGCTGGGTGCGCGAGGGCACCGGCAACTCCG
ACCTCGCGCTCGAGGCGACGAAGAAGGCGCTCGACAAGGCCGGCTGGAAGCCCACCGACATCGAGGCGATCGTCTACGCC
TCGCTCTCGCCCGATCACATGTTCCCGGGCGACGGCTGCTTCCTGAACGCGAAGCTCGGCATCCCCGGCGTGCCGGCCAT
CGACATCCGCAACCAGTGCACCGGCTTCCTGTACGGCCTCTCGGTGGCGGACGCCTGGATCCGCACCGGGATGTACAAGC
GCGTCCTGCTGGTCGGCTCGGAGGTCCACTCCACCGGCCTCGACGTCACCACCCGCGGCCGCGACGTGGCGGTCATCTTC
GGCGACGGGGCCGGCGCGGCGCTGCTCGAGGCGACCGACGACCCGAACCGCGGCGTGCTCTCCTGCCACCTCCACGCGGA
CGGCCGCTTCGCGCGCGACCTGTTCACCGACGCGCCCGGGTCGATCTACCACCCGCGCGTGCAGCCGAGGATGCTCGACG
ACGCCAGCATCTTCCCGCACATGGAGGGGCAGAAGGTGTTCAAGCATGCGGTCGTCCGCATGCCGGAGGTGCTGAAGGAG
GCCTTCGACAAGAACGGCGTCGGGCCGCAGGACCTGAAGGTCCTCGTCCCGCACCAGGCGAACCTCCGCATCGCGCAGAT
GGTCCAGCGCTCGCTCGGGCTGCGCGACGACCAGGTGTTCAACAACATCCAGCGCTACGGCAACACCACCGCGGCGTCGA
TCCCGCTCGCGCTCGCCGAGGCGGTCGAGGCGCGCGGCGTCGCGCGCGGTGACCTGGTGGGACTGTGCGCGTTCGGGGCC
GGCTTTACTTGGGCGAGCGCCCTGGTACGCTGGTGA

Upstream 100 bases:

>100_bases
TTCTCGATCCTGATGGGCGACGCGGTGGAGCCGCGCCGCGAGTTCATCGAGAAGCACGCGCTCGACGTGCAGAACCTGGA
CATCTGAGGAGGAGCCGCCC

Downstream 100 bases:

>100_bases
CGGCTTGATCGCGGTCAGCGGGTGAGGGCCACTCAACAGCGCGTCGGGAGCGCAACGTCCGGAGCAGCGCGCGCGTGTCC
GTGAAGCATCCTGAGGCGTC

Product: 3-oxoacyl-(acyl-carrier-protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MPRAAIVALGTHVPDRVVTNEELTKHMETTDAWIQERTGIQERRWVREGTGNSDLALEATKKALDKAGWKPTDIEAIVYA
SLSPDHMFPGDGCFLNAKLGIPGVPAIDIRNQCTGFLYGLSVADAWIRTGMYKRVLLVGSEVHSTGLDVTTRGRDVAVIF
GDGAGAALLEATDDPNRGVLSCHLHADGRFARDLFTDAPGSIYHPRVQPRMLDDASIFPHMEGQKVFKHAVVRMPEVLKE
AFDKNGVGPQDLKVLVPHQANLRIAQMVQRSLGLRDDQVFNNIQRYGNTTAASIPLALAEAVEARGVARGDLVGLCAFGA
GFTWASALVRW

Sequences:

>Translated_331_residues
MPRAAIVALGTHVPDRVVTNEELTKHMETTDAWIQERTGIQERRWVREGTGNSDLALEATKKALDKAGWKPTDIEAIVYA
SLSPDHMFPGDGCFLNAKLGIPGVPAIDIRNQCTGFLYGLSVADAWIRTGMYKRVLLVGSEVHSTGLDVTTRGRDVAVIF
GDGAGAALLEATDDPNRGVLSCHLHADGRFARDLFTDAPGSIYHPRVQPRMLDDASIFPHMEGQKVFKHAVVRMPEVLKE
AFDKNGVGPQDLKVLVPHQANLRIAQMVQRSLGLRDDQVFNNIQRYGNTTAASIPLALAEAVEARGVARGDLVGLCAFGA
GFTWASALVRW
>Mature_330_residues
PRAAIVALGTHVPDRVVTNEELTKHMETTDAWIQERTGIQERRWVREGTGNSDLALEATKKALDKAGWKPTDIEAIVYAS
LSPDHMFPGDGCFLNAKLGIPGVPAIDIRNQCTGFLYGLSVADAWIRTGMYKRVLLVGSEVHSTGLDVTTRGRDVAVIFG
DGAGAALLEATDDPNRGVLSCHLHADGRFARDLFTDAPGSIYHPRVQPRMLDDASIFPHMEGQKVFKHAVVRMPEVLKEA
FDKNGVGPQDLKVLVPHQANLRIAQMVQRSLGLRDDQVFNNIQRYGNTTAASIPLALAEAVEARGVARGDLVGLCAFGAG
FTWASALVRW

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=326, Percent_Identity=43.2515337423313, Blast_Score=245, Evalue=3e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 36044; Mature: 35912

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRAAIVALGTHVPDRVVTNEELTKHMETTDAWIQERTGIQERRWVREGTGNSDLALEAT
CCCCEEEEECCCCCCHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEHHHH
KKALDKAGWKPTDIEAIVYASLSPDHMFPGDGCFLNAKLGIPGVPAIDIRNQCTGFLYGL
HHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCEEEEEECCCCCCCEECCCCCCCHHHHHH
SVADAWIRTGMYKRVLLVGSEVHSTGLDVTTRGRDVAVIFGDGAGAALLEATDDPNRGVL
HHHHHHHHHHHHHHHEEECCHHHCCCCCEEECCCEEEEEEECCCCEEEEECCCCCCCCEE
SCHLHADGRFARDLFTDAPGSIYHPRVQPRMLDDASIFPHMEGQKVFKHAVVRMPEVLKE
EEEEECCCCHHHHHHHCCCCCEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AFDKNGVGPQDLKVLVPHQANLRIAQMVQRSLGLRDDQVFNNIQRYGNTTAASIPLALAE
HHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHH
AVEARGVARGDLVGLCAFGAGFTWASALVRW
HHHHCCCCCCCCEEHHHHCCCHHHHHHHHCC
>Mature Secondary Structure 
PRAAIVALGTHVPDRVVTNEELTKHMETTDAWIQERTGIQERRWVREGTGNSDLALEAT
CCCEEEEECCCCCCHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEHHHH
KKALDKAGWKPTDIEAIVYASLSPDHMFPGDGCFLNAKLGIPGVPAIDIRNQCTGFLYGL
HHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCEEEEEECCCCCCCEECCCCCCCHHHHHH
SVADAWIRTGMYKRVLLVGSEVHSTGLDVTTRGRDVAVIFGDGAGAALLEATDDPNRGVL
HHHHHHHHHHHHHHHEEECCHHHCCCCCEEECCCEEEEEEECCCCEEEEECCCCCCCCEE
SCHLHADGRFARDLFTDAPGSIYHPRVQPRMLDDASIFPHMEGQKVFKHAVVRMPEVLKE
EEEEECCCCHHHHHHHCCCCCEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AFDKNGVGPQDLKVLVPHQANLRIAQMVQRSLGLRDDQVFNNIQRYGNTTAASIPLALAE
HHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHH
AVEARGVARGDLVGLCAFGAGFTWASALVRW
HHHHCCCCCCCCEEHHHHCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA