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The map label for this gene is 220914924

Identifier: 220914924

GI number: 220914924

Start: 299142

End: 300722

Strand: Reverse

Name: 220914924

Synonym: Mnod_8077

Alternate gene names: NA

Gene position: 300722-299142 (Counterclockwise)

Preceding gene: 220914925

Following gene: 220914921

Centisome position: 65.65

GC content: 74.57

Gene sequence:

>1581_bases
ATGCCGGACGAGAGCCAGAGCGAGACTGTGGACTTCCTCCGGCGCTGCCTTGCCGGTCACGGCAGGCTCGAGACGATCCG
CACGCACATCTCCGTCGTGCTCCTGGCGGAGGATCGCGTGTACAAGCTCAAGCGCGCGGTGCGCTTCCCCTTCGTCGATT
TCTCGGCGCCGGAGGCGCGGCTGGCGGCCTGCGAGGCCGAGCTCGCCCTCAACCGCCGCACGGCGCCCGCCCTGTATCGC
GGGGTGCACCGGATCACGCGGACGCCCGACGGGGGGCTCGCCCTCGACGGCACCGGCCCCCTGGTCGACGCGGTCGTGGC
GATGCGGCGCTTCCCGCAAGGTGACCTGTTCGACGCCATGACCCGGGAGGGGCGGCTCACCCCCGCCCTCGTCGCCGCCC
TCGCTCACCGCATCGCCGCCTTCCACGCCGCCGCGGAGATCAGCCGCGCCCCTGGCGGTGCGGCCGCCATGGCGGCCCTC
GTCGCCCTGAACGACCGGGGGCTGCGGGCCTGCGGGCTCGCAAGCGCCGGAGAGGCCGACGCCCTCACGGCCCGCTTCGA
GGCCGCGCTCGCCCGGCACGGCGACCGGCTGGAGGCGCGGCGCGCCGCCGGCAAGGTGCGCCGCTGCCATGGCGACCTGA
CGCTGCGCAACATCTGCCTGTACGAGGGGGTGCCGACGCCGTTCGACTGCCTCGAATTCGACGAGGCCCTCGCCACGATC
GACGTGCTCTACGACCTCGCCTTCGTGCTGATGGATCTGTGGCATCGCGGCCGGCGCGACCTCGCGAACCTGCTGTTCAA
CCGCTACTTGGACGAGAGCGACGAGGCGGACGGCGCCGGCCTGCTGCCTTTCCTGATGGCGATCCGCGCCGTCATCCGCG
CGCATGTCACGGCGACCCAGGCGGCGGAGGCGCCCGGCGAGACTGCCCGTGCGCTGCGGGACGAGGCGCGGGCCTATCTC
GATCTCGCCGGCACCCTGCTCGCCGAGGAACCTGCGACCCTGGTGGCGGTCGGGGGCCTGAGCGGATCCGGCAAGTCGAC
CTTCGCCGCCGCGCTCGCGCCCTGGCTCGGCGCCCCGCCCGGGGCGCGCATCGTGAGCAGCGACCGCACGCGCAAGCGCC
TGCACGGCGTCAGCGCCGTGACGCGGCTCTCCGACTCGGCCTATGCGCCCTCCGTCTCCGAACGGGTCTATGCGGCGATG
CGCGACGAGGCGGCCCGGGTGCTCGCCACCGGCGGCGCAGTGATCCTCGATGCGGTCTTCGATCGTCCCGAGGCACGGGA
GGCCGTCGAAGCGCTGGCACGGCGGTGCGGCGTCCCCTTCCGGGGGGTGTGGCTGCAGGCGCCCGCGGCGATGCTCGCGG
CCCGCATCCGCGCCCGGCGGGACGATCCCTCCGACGCCACGATCGAGGTCCTGGCCGCGCAGGCCAGCCGCGACTGCGGC
CCGATGACGTGGCATTGCCTCGACGCGCAGCTGCCGGCGGAGACGTTGCGCGCGACGATCCTGGCGAGCTGCGGAACGGG
CGAGGCGAAGGCCGAGGCGAGCCGGGGCGGGACCGCGGGGACCGAGGTGCTCCCGGCCTGA

Upstream 100 bases:

>100_bases
AGCCGTGGGCGATCCGCGCACGGAGCCGGCCGCCGCGGCGGGCCCGCGCGGGCGCGCAGGCGAATCTGGTTTGACCCCCT
CATGTGACGGGACCGATGCC

Downstream 100 bases:

>100_bases
CGGATGAAGCCTCAGGATGAGCCATAGGAATCGGTGCACCCCGAGATGGTGCGTTGTCGATCGAGACCGCGTCAGCCCAC
GCAAGGATGTCCGCCTGACG

Product: aminoglycoside phosphotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 526; Mature: 525

Protein sequence:

>526_residues
MPDESQSETVDFLRRCLAGHGRLETIRTHISVVLLAEDRVYKLKRAVRFPFVDFSAPEARLAACEAELALNRRTAPALYR
GVHRITRTPDGGLALDGTGPLVDAVVAMRRFPQGDLFDAMTREGRLTPALVAALAHRIAAFHAAAEISRAPGGAAAMAAL
VALNDRGLRACGLASAGEADALTARFEAALARHGDRLEARRAAGKVRRCHGDLTLRNICLYEGVPTPFDCLEFDEALATI
DVLYDLAFVLMDLWHRGRRDLANLLFNRYLDESDEADGAGLLPFLMAIRAVIRAHVTATQAAEAPGETARALRDEARAYL
DLAGTLLAEEPATLVAVGGLSGSGKSTFAAALAPWLGAPPGARIVSSDRTRKRLHGVSAVTRLSDSAYAPSVSERVYAAM
RDEAARVLATGGAVILDAVFDRPEAREAVEALARRCGVPFRGVWLQAPAAMLAARIRARRDDPSDATIEVLAAQASRDCG
PMTWHCLDAQLPAETLRATILASCGTGEAKAEASRGGTAGTEVLPA

Sequences:

>Translated_526_residues
MPDESQSETVDFLRRCLAGHGRLETIRTHISVVLLAEDRVYKLKRAVRFPFVDFSAPEARLAACEAELALNRRTAPALYR
GVHRITRTPDGGLALDGTGPLVDAVVAMRRFPQGDLFDAMTREGRLTPALVAALAHRIAAFHAAAEISRAPGGAAAMAAL
VALNDRGLRACGLASAGEADALTARFEAALARHGDRLEARRAAGKVRRCHGDLTLRNICLYEGVPTPFDCLEFDEALATI
DVLYDLAFVLMDLWHRGRRDLANLLFNRYLDESDEADGAGLLPFLMAIRAVIRAHVTATQAAEAPGETARALRDEARAYL
DLAGTLLAEEPATLVAVGGLSGSGKSTFAAALAPWLGAPPGARIVSSDRTRKRLHGVSAVTRLSDSAYAPSVSERVYAAM
RDEAARVLATGGAVILDAVFDRPEAREAVEALARRCGVPFRGVWLQAPAAMLAARIRARRDDPSDATIEVLAAQASRDCG
PMTWHCLDAQLPAETLRATILASCGTGEAKAEASRGGTAGTEVLPA
>Mature_525_residues
PDESQSETVDFLRRCLAGHGRLETIRTHISVVLLAEDRVYKLKRAVRFPFVDFSAPEARLAACEAELALNRRTAPALYRG
VHRITRTPDGGLALDGTGPLVDAVVAMRRFPQGDLFDAMTREGRLTPALVAALAHRIAAFHAAAEISRAPGGAAAMAALV
ALNDRGLRACGLASAGEADALTARFEAALARHGDRLEARRAAGKVRRCHGDLTLRNICLYEGVPTPFDCLEFDEALATID
VLYDLAFVLMDLWHRGRRDLANLLFNRYLDESDEADGAGLLPFLMAIRAVIRAHVTATQAAEAPGETARALRDEARAYLD
LAGTLLAEEPATLVAVGGLSGSGKSTFAAALAPWLGAPPGARIVSSDRTRKRLHGVSAVTRLSDSAYAPSVSERVYAAMR
DEAARVLATGGAVILDAVFDRPEAREAVEALARRCGVPFRGVWLQAPAAMLAARIRARRDDPSDATIEVLAAQASRDCGP
MTWHCLDAQLPAETLRATILASCGTGEAKAEASRGGTAGTEVLPA

Specific function: Some isolated peptides of this protein are able to bind to human U937 monocytoblastic and A549 epithelial cell lines [H]

COG id: COG2187

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR010488 [H]

Pfam domain/function: PF06414 Zeta_toxin [H]

EC number: NA

Molecular weight: Translated: 56020; Mature: 55888

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDESQSETVDFLRRCLAGHGRLETIRTHISVVLLAEDRVYKLKRAVRFPFVDFSAPEAR
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHEEEEEEECHHHHHHHHHHHCCCCCCCCCHHH
LAACEAELALNRRTAPALYRGVHRITRTPDGGLALDGTGPLVDAVVAMRRFPQGDLFDAM
HHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHCCCCCHHHHH
TREGRLTPALVAALAHRIAAFHAAAEISRAPGGAAAMAALVALNDRGLRACGLASAGEAD
HCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHH
ALTARFEAALARHGDRLEARRAAGKVRRCHGDLTLRNICLYEGVPTPFDCLEFDEALATI
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHEECCCCCCHHHHHHHHHHHHH
DVLYDLAFVLMDLWHRGRRDLANLLFNRYLDESDEADGAGLLPFLMAIRAVIRAHVTATQ
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AAEAPGETARALRDEARAYLDLAGTLLAEEPATLVAVGGLSGSGKSTFAAALAPWLGAPP
HHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCC
GARIVSSDRTRKRLHGVSAVTRLSDSAYAPSVSERVYAAMRDEAARVLATGGAVILDAVF
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
DRPEAREAVEALARRCGVPFRGVWLQAPAAMLAARIRARRDDPSDATIEVLAAQASRDCG
CCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCC
PMTWHCLDAQLPAETLRATILASCGTGEAKAEASRGGTAGTEVLPA
CCEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
PDESQSETVDFLRRCLAGHGRLETIRTHISVVLLAEDRVYKLKRAVRFPFVDFSAPEAR
CCCCHHHHHHHHHHHHHCCCHHHHHHHHEEEEEEECHHHHHHHHHHHCCCCCCCCCHHH
LAACEAELALNRRTAPALYRGVHRITRTPDGGLALDGTGPLVDAVVAMRRFPQGDLFDAM
HHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHCCCCCHHHHH
TREGRLTPALVAALAHRIAAFHAAAEISRAPGGAAAMAALVALNDRGLRACGLASAGEAD
HCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHH
ALTARFEAALARHGDRLEARRAAGKVRRCHGDLTLRNICLYEGVPTPFDCLEFDEALATI
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHEECCCCCCHHHHHHHHHHHHH
DVLYDLAFVLMDLWHRGRRDLANLLFNRYLDESDEADGAGLLPFLMAIRAVIRAHVTATQ
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AAEAPGETARALRDEARAYLDLAGTLLAEEPATLVAVGGLSGSGKSTFAAALAPWLGAPP
HHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCC
GARIVSSDRTRKRLHGVSAVTRLSDSAYAPSVSERVYAAMRDEAARVLATGGAVILDAVF
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
DRPEAREAVEALARRCGVPFRGVWLQAPAAMLAARIRARRDDPSDATIEVLAAQASRDCG
CCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCC
PMTWHCLDAQLPAETLRATILASCGTGEAKAEASRGGTAGTEVLPA
CCEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]