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The map label for this gene is aapM [H]

Identifier: 220914744

GI number: 220914744

Start: 90940

End: 92124

Strand: Reverse

Name: aapM [H]

Synonym: Mnod_7858

Alternate gene names: 220914744

Gene position: 92124-90940 (Counterclockwise)

Preceding gene: 220914745

Following gene: 220914743

Centisome position: 20.11

GC content: 60.51

Gene sequence:

>1185_bases
ATGTCGCAGACCACCACCGCCAAGATTTCGGAAGCTGCCGGCGACCCGGTACCATCAATCGCCGGCATTCCGGCAGCCCC
GATCACGCGCGCCCCACCGCTGGCGGCCGGCGCAGGACCACTGGGCTGGGCGCGGACGAACCTGTTCAGCTCGATCCCGT
CCACGATCGTGACATTGGTGCTGCTCATTCTGCTGGCACGATGGGCAACCGAATTCGTGAATTGGGCCATCCTGCATGCC
GTCTGGTCCGTACCGAACACCGCGACCGGTCCCGACACTGCCGCCTGCCGCGATGCGAAAGGGATTGGCGCGTGCTGGGC
TGTCATTAGCGAGAAGTATCGGTTTATCCTGTTCGGCCGCTACTTGTACGAGGAGCAGTGGCGGCCGGCAATCGTCATCG
TACTTTTTATCGGCCTGTATGTTGTATCGGCCATGCGCCAGTTCTGGCGCAAGGAGTTGATTTTAATTTGGATCACCACG
CTTACGGTCGTCGGAGTGCTGATGTGGGGTGGAGTCTTCGGACTGACTTACGTACCACAAGATAGTTGGGGCGGACTTCC
GATCACGCTGATCCTAGCCACATTCGGTCTTGCCTGTGCCTTTCCGCTTTCGATCCTGGTCGCACTGGGCCGTCGAGCAA
CTAATCTGCCGGCGATCCGGGTTCTCTGCACGGTTTATGTTGAGCTGATCCGCGGCGTGCCGCTGATCACAGTTCTCTTT
ATGGCCAGCGTGATGTTCCCGCTGTTCATGCCGGCAGGACTCAATCCGGACAAGCTACTGCGGGCGCAGGTAGCGGTGAT
CCTGTTCGCCGCGGCCTATCTCGCGGAAGTGGTCCGGGGCGGGCTGCAGACCTTGCCGAAGGGACAGTACGAGGCGGCCG
ACGCGCTTGGACTTGGTTACTGGCACAAGACAGCCTTCATCATCTTGCCGCAGGCCCTGCGGCTCGTGATACCGCCTTTG
GTCAACACCTTCATCGGCTTCTTCAAAGACACTTCGCTCGTGCTCATCATCGGCCTGTTCGACCTGCTGACCGCAGGCAA
GGTGGCGATGGCCGACCTCGTCTGGCAGCCCTACAGCACAGAGGTCTATCTCGTGCTCGCGGCCATCTACTTCGCTTTCT
GCTACGTCATGGCCCGCTACAGCCGCGGGCTGGAGCAGGGATTCAGCCGTAGCACTAAGCGGTAA

Upstream 100 bases:

>100_bases
AATTGCCATGGTTATGCTGGTCTACCTGGTGATCAGTCTCTCGATTAGCCTATTCATGAATTGGTACAATGGGCGCATCG
CGCTCGTGGAGCGCTGAGCC

Downstream 100 bases:

>100_bases
GGGGGATCACCATGAGCCAGGCAACGACAATCGACCGGGCCAACGCAGCGACCTGCGAACAGCCAGCCATCATTCTTGAC
AAAGTAAACAAGTGGTACGG

Product: polar amino acid ABC transporter, inner membrane subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MSQTTTAKISEAAGDPVPSIAGIPAAPITRAPPLAAGAGPLGWARTNLFSSIPSTIVTLVLLILLARWATEFVNWAILHA
VWSVPNTATGPDTAACRDAKGIGACWAVISEKYRFILFGRYLYEEQWRPAIVIVLFIGLYVVSAMRQFWRKELILIWITT
LTVVGVLMWGGVFGLTYVPQDSWGGLPITLILATFGLACAFPLSILVALGRRATNLPAIRVLCTVYVELIRGVPLITVLF
MASVMFPLFMPAGLNPDKLLRAQVAVILFAAAYLAEVVRGGLQTLPKGQYEAADALGLGYWHKTAFIILPQALRLVIPPL
VNTFIGFFKDTSLVLIIGLFDLLTAGKVAMADLVWQPYSTEVYLVLAAIYFAFCYVMARYSRGLEQGFSRSTKR

Sequences:

>Translated_394_residues
MSQTTTAKISEAAGDPVPSIAGIPAAPITRAPPLAAGAGPLGWARTNLFSSIPSTIVTLVLLILLARWATEFVNWAILHA
VWSVPNTATGPDTAACRDAKGIGACWAVISEKYRFILFGRYLYEEQWRPAIVIVLFIGLYVVSAMRQFWRKELILIWITT
LTVVGVLMWGGVFGLTYVPQDSWGGLPITLILATFGLACAFPLSILVALGRRATNLPAIRVLCTVYVELIRGVPLITVLF
MASVMFPLFMPAGLNPDKLLRAQVAVILFAAAYLAEVVRGGLQTLPKGQYEAADALGLGYWHKTAFIILPQALRLVIPPL
VNTFIGFFKDTSLVLIIGLFDLLTAGKVAMADLVWQPYSTEVYLVLAAIYFAFCYVMARYSRGLEQGFSRSTKR
>Mature_393_residues
SQTTTAKISEAAGDPVPSIAGIPAAPITRAPPLAAGAGPLGWARTNLFSSIPSTIVTLVLLILLARWATEFVNWAILHAV
WSVPNTATGPDTAACRDAKGIGACWAVISEKYRFILFGRYLYEEQWRPAIVIVLFIGLYVVSAMRQFWRKELILIWITTL
TVVGVLMWGGVFGLTYVPQDSWGGLPITLILATFGLACAFPLSILVALGRRATNLPAIRVLCTVYVELIRGVPLITVLFM
ASVMFPLFMPAGLNPDKLLRAQVAVILFAAAYLAEVVRGGLQTLPKGQYEAADALGLGYWHKTAFIILPQALRLVIPPLV
NTFIGFFKDTSLVLIIGLFDLLTAGKVAMADLVWQPYSTEVYLVLAAIYFAFCYVMARYSRGLEQGFSRSTKR

Specific function: Part of a binding-protein-dependent transport system for L-amino acids, affects the uptake as well as efflux of these amino acids. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082239, Length=353, Percent_Identity=49.0084985835694, Blast_Score=304, Evalue=6e-84,
Organism=Escherichia coli, GI1788226, Length=221, Percent_Identity=31.2217194570136, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786873, Length=195, Percent_Identity=34.3589743589744, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI1787030, Length=206, Percent_Identity=33.0097087378641, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1786874, Length=225, Percent_Identity=29.7777777777778, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI48994930, Length=87, Percent_Identity=40.2298850574713, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1788645, Length=221, Percent_Identity=28.0542986425339, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1787087, Length=131, Percent_Identity=31.2977099236641, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 43006; Mature: 42874

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQTTTAKISEAAGDPVPSIAGIPAAPITRAPPLAAGAGPLGWARTNLFSSIPSTIVTLV
CCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LLILLARWATEFVNWAILHAVWSVPNTATGPDTAACRDAKGIGACWAVISEKYRFILFGR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHH
YLYEEQWRPAIVIVLFIGLYVVSAMRQFWRKELILIWITTLTVVGVLMWGGVFGLTYVPQ
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCC
DSWGGLPITLILATFGLACAFPLSILVALGRRATNLPAIRVLCTVYVELIRGVPLITVLF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHH
MASVMFPLFMPAGLNPDKLLRAQVAVILFAAAYLAEVVRGGLQTLPKGQYEAADALGLGY
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
WHKTAFIILPQALRLVIPPLVNTFIGFFKDTSLVLIIGLFDLLTAGKVAMADLVWQPYST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCC
EVYLVLAAIYFAFCYVMARYSRGLEQGFSRSTKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SQTTTAKISEAAGDPVPSIAGIPAAPITRAPPLAAGAGPLGWARTNLFSSIPSTIVTLV
CCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LLILLARWATEFVNWAILHAVWSVPNTATGPDTAACRDAKGIGACWAVISEKYRFILFGR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHH
YLYEEQWRPAIVIVLFIGLYVVSAMRQFWRKELILIWITTLTVVGVLMWGGVFGLTYVPQ
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCC
DSWGGLPITLILATFGLACAFPLSILVALGRRATNLPAIRVLCTVYVELIRGVPLITVLF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHH
MASVMFPLFMPAGLNPDKLLRAQVAVILFAAAYLAEVVRGGLQTLPKGQYEAADALGLGY
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
WHKTAFIILPQALRLVIPPLVNTFIGFFKDTSLVLIIGLFDLLTAGKVAMADLVWQPYST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCC
EVYLVLAAIYFAFCYVMARYSRGLEQGFSRSTKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8898392 [H]