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The map label for this gene is xerC [H]

Identifier: 220905619

GI number: 220905619

Start: 2839403

End: 2840599

Strand: Reverse

Name: xerC [H]

Synonym: Ddes_2359

Alternate gene names: 220905619

Gene position: 2840599-2839403 (Counterclockwise)

Preceding gene: 220905620

Following gene: 220905618

Centisome position: 98.86

GC content: 54.72

Gene sequence:

>1197_bases
ATGGCTTCCCTTACCCGCCACCAGACCGACAGAGTCGGCGTCTTCTACATCCTCGGCAAGCAACGCGCCAAGAGCAAAAC
GCCTTCCGGCGAAGCCGTTCCCACCGAAAAGGCAGATAAAATCTATTATATTATGTACCGCCTTGACGGGAAAAAGGTTG
AAGAAAAGGTAGGGCGCGAGTCTGAACGCATGACCGTTGCCAAGGCCGCCAAGATACGTGAACAGCGGATTAACGGAGTC
ACACTGCCCAACACGGAACGCCGCCGTCAGCGCCTTGAGAAAGCTCAGGCAGAGGCCGGACGTTGGACAATCGGCAAATT
GTGGAAAGCCTACAAAGATAACAACCCCGGCCTTAAAGGGATTGTCACCGACGAGAACCGCTTCAAAAACTACCTGAGCG
GCTTTACAAAATTATCACCCGAAGAGCTGACCACACAGATGGTGGACACCTTGCGGCTGAAGCTCCTGAAGTCCGGCAAG
AAGGCCGGAACTACCAAGAATGTGTTGGAGCTTTTACGGCGTATTATCAATTTTGGCGTCAAAAAGGGGCTGTGCGCGTG
GCAAGACCCGTCGCGTCTGCACTTTGAGATGCCCAAGCTGAACAACGTCAAAACGGAAATGCTGACCAAGGAAGAACGCG
CCCGTTTCATCGAAGCAGCAAAAGCGGCCCCCAACCGCAAGGCCGGACAGCTTATGCTCATGGCCTACTATACCGGGATG
CGCCGCAATGAGCTTTTCGGCCTCAAATGGGCGCACATCGACTTTGAGCACGGTTTTATCAATATCGTGGGTGAGAAGCA
GGAAGGAGCCAAGAGCAACCGGGATGAACGCATTCCCCTCAGCCCCCCGGTGCGTGAACTGCTGGCGGAAGTGGGGGACA
ACGGCAGCGAGTATGTGTTTCCCGGCAAGGACGGGCGTAGCCGCATGATCGACATGAACAAGCAGGTGAACGCCATTAAG
GCCGCCGCCGGACTGCCCAAGGATTTCCGGCCCCTGCACGGCTTGCGGCATACCTTCGCCAGCGTGGCAGTGTCCAATGG
AGTTCCCCTCTCTCACGTCCAAAAGCTGCTGACTCACAAAGACCCCACTTTGACGCAACGCTATGCGCACTTGGAGGATG
AGGCGTTGAAAAATGCGGCTAATATGGTGGGTAATTTTCTCACTATCCCAGATTCAACAAAAATAGCTGGGGAATGA

Upstream 100 bases:

>100_bases
CCTTTCGTTTCACTCCTACATTTTGGCCTTGTTTTCGACTTGACTTGGTGGGAATATGGTGGGAATAAATTGCTGAACAC
TTCCACGCGGAGGAATCGGC

Downstream 100 bases:

>100_bases
GGTTCTTGCTCAGATCGCTCAAGCGCCTTACAGTAATCAGGTACCCTTCAAGTGCCACAACGCCACCAAGCCCAAAGTGA
TTGCCCTCCCAAGGAGCAGA

Product: integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MASLTRHQTDRVGVFYILGKQRAKSKTPSGEAVPTEKADKIYYIMYRLDGKKVEEKVGRESERMTVAKAAKIREQRINGV
TLPNTERRRQRLEKAQAEAGRWTIGKLWKAYKDNNPGLKGIVTDENRFKNYLSGFTKLSPEELTTQMVDTLRLKLLKSGK
KAGTTKNVLELLRRIINFGVKKGLCAWQDPSRLHFEMPKLNNVKTEMLTKEERARFIEAAKAAPNRKAGQLMLMAYYTGM
RRNELFGLKWAHIDFEHGFINIVGEKQEGAKSNRDERIPLSPPVRELLAEVGDNGSEYVFPGKDGRSRMIDMNKQVNAIK
AAAGLPKDFRPLHGLRHTFASVAVSNGVPLSHVQKLLTHKDPTLTQRYAHLEDEALKNAANMVGNFLTIPDSTKIAGE

Sequences:

>Translated_398_residues
MASLTRHQTDRVGVFYILGKQRAKSKTPSGEAVPTEKADKIYYIMYRLDGKKVEEKVGRESERMTVAKAAKIREQRINGV
TLPNTERRRQRLEKAQAEAGRWTIGKLWKAYKDNNPGLKGIVTDENRFKNYLSGFTKLSPEELTTQMVDTLRLKLLKSGK
KAGTTKNVLELLRRIINFGVKKGLCAWQDPSRLHFEMPKLNNVKTEMLTKEERARFIEAAKAAPNRKAGQLMLMAYYTGM
RRNELFGLKWAHIDFEHGFINIVGEKQEGAKSNRDERIPLSPPVRELLAEVGDNGSEYVFPGKDGRSRMIDMNKQVNAIK
AAAGLPKDFRPLHGLRHTFASVAVSNGVPLSHVQKLLTHKDPTLTQRYAHLEDEALKNAANMVGNFLTIPDSTKIAGE
>Mature_397_residues
ASLTRHQTDRVGVFYILGKQRAKSKTPSGEAVPTEKADKIYYIMYRLDGKKVEEKVGRESERMTVAKAAKIREQRINGVT
LPNTERRRQRLEKAQAEAGRWTIGKLWKAYKDNNPGLKGIVTDENRFKNYLSGFTKLSPEELTTQMVDTLRLKLLKSGKK
AGTTKNVLELLRRIINFGVKKGLCAWQDPSRLHFEMPKLNNVKTEMLTKEERARFIEAAKAAPNRKAGQLMLMAYYTGMR
RNELFGLKWAHIDFEHGFINIVGEKQEGAKSNRDERIPLSPPVRELLAEVGDNGSEYVFPGKDGRSRMIDMNKQVNAIKA
AAGLPKDFRPLHGLRHTFASVAVSNGVPLSHVQKLLTHKDPTLTQRYAHLEDEALKNAANMVGNFLTIPDSTKIAGE

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4973

COG function: function code L; Site-specific recombinase XerC

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=235, Percent_Identity=26.8085106382979, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1786748, Length=207, Percent_Identity=27.0531400966184, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI2367104, Length=169, Percent_Identity=28.4023668639053, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 44955; Mature: 44823

Theoretical pI: Translated: 10.58; Mature: 10.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASLTRHQTDRVGVFYILGKQRAKSKTPSGEAVPTEKADKIYYIMYRLDGKKVEEKVGRE
CCCCCCCCCCCCEEEEEECCHHHCCCCCCCCCCCCCCCCCEEEEEEEECCHHHHHHHCCH
SERMTVAKAAKIREQRINGVTLPNTERRRQRLEKAQAEAGRWTIGKLWKAYKDNNPGLKG
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEE
IVTDENRFKNYLSGFTKLSPEELTTQMVDTLRLKLLKSGKKAGTTKNVLELLRRIINFGV
EECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCH
KKGLCAWQDPSRLHFEMPKLNNVKTEMLTKEERARFIEAAKAAPNRKAGQLMLMAYYTGM
HCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHCCC
RRNELFGLKWAHIDFEHGFINIVGEKQEGAKSNRDERIPLSPPVRELLAEVGDNGSEYVF
CCCCCCCEEEEEEEECCCEEEEEECCHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEE
PGKDGRSRMIDMNKQVNAIKAAAGLPKDFRPLHGLRHTFASVAVSNGVPLSHVQKLLTHK
CCCCCCCHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
DPTLTQRYAHLEDEALKNAANMVGNFLTIPDSTKIAGE
CCHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCC
>Mature Secondary Structure 
ASLTRHQTDRVGVFYILGKQRAKSKTPSGEAVPTEKADKIYYIMYRLDGKKVEEKVGRE
CCCCCCCCCCCEEEEEECCHHHCCCCCCCCCCCCCCCCCEEEEEEEECCHHHHHHHCCH
SERMTVAKAAKIREQRINGVTLPNTERRRQRLEKAQAEAGRWTIGKLWKAYKDNNPGLKG
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEE
IVTDENRFKNYLSGFTKLSPEELTTQMVDTLRLKLLKSGKKAGTTKNVLELLRRIINFGV
EECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCH
KKGLCAWQDPSRLHFEMPKLNNVKTEMLTKEERARFIEAAKAAPNRKAGQLMLMAYYTGM
HCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHCCC
RRNELFGLKWAHIDFEHGFINIVGEKQEGAKSNRDERIPLSPPVRELLAEVGDNGSEYVF
CCCCCCCEEEEEEEECCCEEEEEECCHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEE
PGKDGRSRMIDMNKQVNAIKAAAGLPKDFRPLHGLRHTFASVAVSNGVPLSHVQKLLTHK
CCCCCCCHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
DPTLTQRYAHLEDEALKNAANMVGNFLTIPDSTKIAGE
CCHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA