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The map label for this gene is yciR [C]

Identifier: 220905545

GI number: 220905545

Start: 2749785

End: 2752034

Strand: Direct

Name: yciR [C]

Synonym: Ddes_2284

Alternate gene names: 220905545

Gene position: 2749785-2752034 (Clockwise)

Preceding gene: 220905543

Following gene: 220905547

Centisome position: 95.7

GC content: 57.69

Gene sequence:

>2250_bases
ATGAAAAACAAACCCGCCCCAACCGACATCAAAAAAAATTTCGCTGTAGCCCCCATGACATGCCTCGCAAGCGGCAGAAT
GGAAGAGCAGTGCTATTCAGGCGTGCTGCGCAGCGTCTACGCCGAAATATATCTTCTGGACTTTGAAAAGGACGAAGCGC
GCGAACTGTACAGGGGCGATGACACGCTTCTGGGACCTTCGGGCGAATTCACCCTGTCGGAGCTTTTTACCGAGGCTCTG
ACCAGGCTCGTCCACCCTGACGACCACAATGCGCTGCTGCGCTTCTGGGACCCTTTGTCCAGGCAGGATCTTGAAAAAAA
CGGCCTGCCGTTCTCAACGCTTGACGTGCGCAGAAAATGCCACGACCTGAGCTACCGCTGGACGCGCATTACCGCATTTC
CCGTCCGTCAGCCCGGCGGGCATTTCGTATACCTTGTCTGCGTGCAGGATGTGGACGACCTCAAGCGCGCGGCCACCATT
GTGCGTGAAAATGAGCTTCTCCAGCAGCAGAAGCTCGATAACCTGCGCTACAAGGCCGTGGTGGACCATACACGCACGCT
GGTATTCGAGTGGCGCAATAATGATCTTACCTACATCAGTCCCCGCATAGGCGAACTGCTGGCCGGAAATTACGATGGCC
GCATTCCCTTTGATGTCTGGCGTGAGGACAATGTGCTGTACAGCGGCGACAGCGCCGCCTTTGACACCTGCCTTTCACGT
CTGGCCCTGGGCATACGCTCCGGCGAAATGACCCTGCGCCTGCGCCGCCGCGACGGGCAGTTCATCTGGTGCAAGGTCAC
CTATACCTGCCTGGCGGACGACAGCCCGGGTGAACGCTACATCGGCACCATCAACGACGTGGATGCCGCCACCCGCACAG
AGCAGGCCCTGCGCCTGCGAGCCGAGCACGATCCCCTCACAGGGGCGTACAATACCCAGACATTTTTTGAAAAGGTAGAA
GCGCTGCTGCGCGAGTATCCCACAGAGCCGTACGCCGTCCTGCGCTTTGACGTGGCGGGCTTCAAGGCCATCAACGAAGC
CTTCAGCCTGGAAGAAGGCAACCGCCTGCTGCGGGCCATCGCCCGCCTCATCCGCCAGCGCATCAACACCCAGTGCGAGG
CTTACGCCCGCCTTACGGCCGATGTGTTTGCCGTGTGCATCACTGGCGACATCAACCGGATAAAAAACTTCATCCACTCC
CTTTCCCGCAGGCTCGAGCATTACTCCGACACATTCAGGGTCAAGCTTTTCTTCGGCGTCTGCCAGGTGGAAAATCGCCG
GACTCCTGCCCACGTGCTCTGCGACTGGGCCTATCTGGCGCAAAAAACCATCAAGGGCAGCGACCTTGCCAACTATGCCT
TTTATGACAACGCGCTGCGCCAGCGCCTGCATGACGAAAGCTACATTACCGACCAGATGTACCGCGCACTGGAGCAAAAA
CAGTTCAAGCTCTACCTGCAGCCCAAGGTGGAGCTGTCGAGCGGCCGCATCGTGGGGGCCGAGGCTCTTGTACGCTGGCA
GCACCCGCACGACGGACTGATCCTGCCAGGCCGCTTTGTGCCGCTTTTCGAGCGCAACGGTTTTATCGTGCGTCTCGATG
AATACATCTGGGACCTCACCTGCCAGAACCTGCGCATGTGGCTGGACAAGGGCTACAAACCCATGCCCGTCTCGGTAAAT
ATGTCGCGCCTGCACTTTAATGACGGCGCTCTGACAAAAAAACTGGTTCAGCTTGTAGACAAATACCGCCTGCCGCGCCA
CCTGCTCGAGCTGGAACTCACCGAAAGTGCCTTTTTCAAAAATGAAAAGGCCCTCATTCACATCATGTGTGAACTGCAGG
CCGAAGGTTTTATTTTTTCAATGGATGACTTTGGTACGGGCTATTCTTCGCTGAGCACCCTGCGCGCCCTGCCGTTCAAC
ATCGTCAAGCTGGACCGCGCCTTCATCAGTGACGGCACGGACAACGAACGCGGCCAGATTGTGGCCCGCAACACTATTGC
CCTTGCCAAAGACCTGCACATGCAGATCGTGGCTGAAGGCGTTGAAACCCTTGATCAGGCCCGCTTTCTGCTCAGTTGCG
GCTGCAACTGCGCCCAGGGCTTCTACTATTCCCAGCCGCTGGACCAGGACGCCTTTGAGGTGCTTTCCTTTATTCAGGAA
AAAGCCTTCTGGGTGGACCCCCAGCTGGCCAACGACGCCCGCAATCTGGGCCTGCCCCTCAGCGACGAAAAGCCTTTTTA
CGATTTCTAG

Upstream 100 bases:

>100_bases
AGTGCAGCTCATTTGCAAAACGCCGGGTCCGGTGCTAGGCTCAAGACTTGACAGTCCGGCGTCAGCGCCGTATCCGTGCG
CAACCAAACAAGCGTTGCTT

Downstream 100 bases:

>100_bases
CCCACCCGCCGTTGAGACGCGCAGTCTCCAATCCTCCGCTCTCAAAAACATTGCCATGCCCGCGCAGCGTTTGACTACAC
AGGTTTGCGGCGCTGTTTTC

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 749; Mature: 749

Protein sequence:

>749_residues
MKNKPAPTDIKKNFAVAPMTCLASGRMEEQCYSGVLRSVYAEIYLLDFEKDEARELYRGDDTLLGPSGEFTLSELFTEAL
TRLVHPDDHNALLRFWDPLSRQDLEKNGLPFSTLDVRRKCHDLSYRWTRITAFPVRQPGGHFVYLVCVQDVDDLKRAATI
VRENELLQQQKLDNLRYKAVVDHTRTLVFEWRNNDLTYISPRIGELLAGNYDGRIPFDVWREDNVLYSGDSAAFDTCLSR
LALGIRSGEMTLRLRRRDGQFIWCKVTYTCLADDSPGERYIGTINDVDAATRTEQALRLRAEHDPLTGAYNTQTFFEKVE
ALLREYPTEPYAVLRFDVAGFKAINEAFSLEEGNRLLRAIARLIRQRINTQCEAYARLTADVFAVCITGDINRIKNFIHS
LSRRLEHYSDTFRVKLFFGVCQVENRRTPAHVLCDWAYLAQKTIKGSDLANYAFYDNALRQRLHDESYITDQMYRALEQK
QFKLYLQPKVELSSGRIVGAEALVRWQHPHDGLILPGRFVPLFERNGFIVRLDEYIWDLTCQNLRMWLDKGYKPMPVSVN
MSRLHFNDGALTKKLVQLVDKYRLPRHLLELELTESAFFKNEKALIHIMCELQAEGFIFSMDDFGTGYSSLSTLRALPFN
IVKLDRAFISDGTDNERGQIVARNTIALAKDLHMQIVAEGVETLDQARFLLSCGCNCAQGFYYSQPLDQDAFEVLSFIQE
KAFWVDPQLANDARNLGLPLSDEKPFYDF

Sequences:

>Translated_749_residues
MKNKPAPTDIKKNFAVAPMTCLASGRMEEQCYSGVLRSVYAEIYLLDFEKDEARELYRGDDTLLGPSGEFTLSELFTEAL
TRLVHPDDHNALLRFWDPLSRQDLEKNGLPFSTLDVRRKCHDLSYRWTRITAFPVRQPGGHFVYLVCVQDVDDLKRAATI
VRENELLQQQKLDNLRYKAVVDHTRTLVFEWRNNDLTYISPRIGELLAGNYDGRIPFDVWREDNVLYSGDSAAFDTCLSR
LALGIRSGEMTLRLRRRDGQFIWCKVTYTCLADDSPGERYIGTINDVDAATRTEQALRLRAEHDPLTGAYNTQTFFEKVE
ALLREYPTEPYAVLRFDVAGFKAINEAFSLEEGNRLLRAIARLIRQRINTQCEAYARLTADVFAVCITGDINRIKNFIHS
LSRRLEHYSDTFRVKLFFGVCQVENRRTPAHVLCDWAYLAQKTIKGSDLANYAFYDNALRQRLHDESYITDQMYRALEQK
QFKLYLQPKVELSSGRIVGAEALVRWQHPHDGLILPGRFVPLFERNGFIVRLDEYIWDLTCQNLRMWLDKGYKPMPVSVN
MSRLHFNDGALTKKLVQLVDKYRLPRHLLELELTESAFFKNEKALIHIMCELQAEGFIFSMDDFGTGYSSLSTLRALPFN
IVKLDRAFISDGTDNERGQIVARNTIALAKDLHMQIVAEGVETLDQARFLLSCGCNCAQGFYYSQPLDQDAFEVLSFIQE
KAFWVDPQLANDARNLGLPLSDEKPFYDF
>Mature_749_residues
MKNKPAPTDIKKNFAVAPMTCLASGRMEEQCYSGVLRSVYAEIYLLDFEKDEARELYRGDDTLLGPSGEFTLSELFTEAL
TRLVHPDDHNALLRFWDPLSRQDLEKNGLPFSTLDVRRKCHDLSYRWTRITAFPVRQPGGHFVYLVCVQDVDDLKRAATI
VRENELLQQQKLDNLRYKAVVDHTRTLVFEWRNNDLTYISPRIGELLAGNYDGRIPFDVWREDNVLYSGDSAAFDTCLSR
LALGIRSGEMTLRLRRRDGQFIWCKVTYTCLADDSPGERYIGTINDVDAATRTEQALRLRAEHDPLTGAYNTQTFFEKVE
ALLREYPTEPYAVLRFDVAGFKAINEAFSLEEGNRLLRAIARLIRQRINTQCEAYARLTADVFAVCITGDINRIKNFIHS
LSRRLEHYSDTFRVKLFFGVCQVENRRTPAHVLCDWAYLAQKTIKGSDLANYAFYDNALRQRLHDESYITDQMYRALEQK
QFKLYLQPKVELSSGRIVGAEALVRWQHPHDGLILPGRFVPLFERNGFIVRLDEYIWDLTCQNLRMWLDKGYKPMPVSVN
MSRLHFNDGALTKKLVQLVDKYRLPRHLLELELTESAFFKNEKALIHIMCELQAEGFIFSMDDFGTGYSSLSTLRALPFN
IVKLDRAFISDGTDNERGQIVARNTIALAKDLHMQIVAEGVETLDQARFLLSCGCNCAQGFYYSQPLDQDAFEVLSFIQE
KAFWVDPQLANDARNLGLPLSDEKPFYDF

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=441, Percent_Identity=28.7981859410431, Blast_Score=183, Evalue=3e-47,
Organism=Escherichia coli, GI226510982, Length=275, Percent_Identity=34.9090909090909, Blast_Score=159, Evalue=6e-40,
Organism=Escherichia coli, GI87081921, Length=275, Percent_Identity=29.4545454545455, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1790496, Length=241, Percent_Identity=31.1203319502075, Blast_Score=143, Evalue=5e-35,
Organism=Escherichia coli, GI1786507, Length=258, Percent_Identity=32.1705426356589, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI1787055, Length=422, Percent_Identity=25.5924170616114, Blast_Score=130, Evalue=4e-31,
Organism=Escherichia coli, GI1788502, Length=282, Percent_Identity=30.8510638297872, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI87081845, Length=233, Percent_Identity=30.0429184549356, Blast_Score=124, Evalue=3e-29,
Organism=Escherichia coli, GI87081743, Length=237, Percent_Identity=32.0675105485232, Blast_Score=122, Evalue=8e-29,
Organism=Escherichia coli, GI87081980, Length=243, Percent_Identity=32.9218106995885, Blast_Score=120, Evalue=4e-28,
Organism=Escherichia coli, GI87082096, Length=418, Percent_Identity=23.444976076555, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1788849, Length=251, Percent_Identity=27.8884462151394, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 86317; Mature: 86317

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS50113 PAC ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKPAPTDIKKNFAVAPMTCLASGRMEEQCYSGVLRSVYAEIYLLDFEKDEARELYRGD
CCCCCCCCCHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHCCC
DTLLGPSGEFTLSELFTEALTRLVHPDDHNALLRFWDPLSRQDLEKNGLPFSTLDVRRKC
CCEECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHCCCCCHHHHHHHHH
HDLSYRWTRITAFPVRQPGGHFVYLVCVQDVDDLKRAATIVRENELLQQQKLDNLRYKAV
HCCCEEEEEEEEEECCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHE
VDHTRTLVFEWRNNDLTYISPRIGELLAGNYDGRIPFDVWREDNVLYSGDSAAFDTCLSR
ECCCEEEEEEEECCCEEEECCHHHHHHCCCCCCCCCHHEECCCCEEECCCCHHHHHHHHH
LALGIRSGEMTLRLRRRDGQFIWCKVTYTCLADDSPGERYIGTINDVDAATRTEQALRLR
HHHHCCCCCEEEEEEECCCCEEEEEEEEEEEECCCCCCCEEECCCCCCHHHHHHHHHHHH
AEHDPLTGAYNTQTFFEKVEALLREYPTEPYAVLRFDVAGFKAINEAFSLEEGNRLLRAI
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHCHHHHHHHHHHH
ARLIRQRINTQCEAYARLTADVFAVCITGDINRIKNFIHSLSRRLEHYSDTFRVKLFFGV
HHHHHHHHCHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEE
CQVENRRTPAHVLCDWAYLAQKTIKGSDLANYAFYDNALRQRLHDESYITDQMYRALEQK
EEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHC
QFKLYLQPKVELSSGRIVGAEALVRWQHPHDGLILPGRFVPLFERNGFIVRLDEYIWDLT
CEEEEEECCEEECCCCEEEHHHHEEECCCCCCEEECCCEEEEEECCCEEEEEHHHHHHHH
CQNLRMWLDKGYKPMPVSVNMSRLHFNDGALTKKLVQLVDKYRLPRHLLELELTESAFFK
HHHHHHHHHCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHC
NEKALIHIMCELQAEGFIFSMDDFGTGYSSLSTLRALPFNIVKLDRAFISDGTDNERGQI
CCCEEEEEEEEECCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCEE
VARNTIALAKDLHMQIVAEGVETLDQARFLLSCGCNCAQGFYYSQPLDQDAFEVLSFIQE
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCHHHHHHHHHHHH
KAFWVDPQLANDARNLGLPLSDEKPFYDF
HHEECCCHHHCCHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MKNKPAPTDIKKNFAVAPMTCLASGRMEEQCYSGVLRSVYAEIYLLDFEKDEARELYRGD
CCCCCCCCCHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHCCC
DTLLGPSGEFTLSELFTEALTRLVHPDDHNALLRFWDPLSRQDLEKNGLPFSTLDVRRKC
CCEECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHCCCCCHHHHHHHHH
HDLSYRWTRITAFPVRQPGGHFVYLVCVQDVDDLKRAATIVRENELLQQQKLDNLRYKAV
HCCCEEEEEEEEEECCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHE
VDHTRTLVFEWRNNDLTYISPRIGELLAGNYDGRIPFDVWREDNVLYSGDSAAFDTCLSR
ECCCEEEEEEEECCCEEEECCHHHHHHCCCCCCCCCHHEECCCCEEECCCCHHHHHHHHH
LALGIRSGEMTLRLRRRDGQFIWCKVTYTCLADDSPGERYIGTINDVDAATRTEQALRLR
HHHHCCCCCEEEEEEECCCCEEEEEEEEEEEECCCCCCCEEECCCCCCHHHHHHHHHHHH
AEHDPLTGAYNTQTFFEKVEALLREYPTEPYAVLRFDVAGFKAINEAFSLEEGNRLLRAI
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHCHHHHHHHHHHH
ARLIRQRINTQCEAYARLTADVFAVCITGDINRIKNFIHSLSRRLEHYSDTFRVKLFFGV
HHHHHHHHCHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEE
CQVENRRTPAHVLCDWAYLAQKTIKGSDLANYAFYDNALRQRLHDESYITDQMYRALEQK
EEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHC
QFKLYLQPKVELSSGRIVGAEALVRWQHPHDGLILPGRFVPLFERNGFIVRLDEYIWDLT
CEEEEEECCEEECCCCEEEHHHHEEECCCCCCEEECCCEEEEEECCCEEEEEHHHHHHHH
CQNLRMWLDKGYKPMPVSVNMSRLHFNDGALTKKLVQLVDKYRLPRHLLELELTESAFFK
HHHHHHHHHCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHC
NEKALIHIMCELQAEGFIFSMDDFGTGYSSLSTLRALPFNIVKLDRAFISDGTDNERGQI
CCCEEEEEEEEECCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCEE
VARNTIALAKDLHMQIVAEGVETLDQARFLLSCGCNCAQGFYYSQPLDQDAFEVLSFIQE
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCHHHHHHHHHHHH
KAFWVDPQLANDARNLGLPLSDEKPFYDF
HHEECCCHHHCCHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]