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The map label for this gene is yheS [H]

Identifier: 220905465

GI number: 220905465

Start: 2656008

End: 2658017

Strand: Direct

Name: yheS [H]

Synonym: Ddes_2203

Alternate gene names: 220905465

Gene position: 2656008-2658017 (Clockwise)

Preceding gene: 220905464

Following gene: 220905466

Centisome position: 92.43

GC content: 60.3

Gene sequence:

>2010_bases
GTGAAGATAACGATTCAGGAACTTTCCAAGTCATTTGGCGGCCGGGATATTTTCAGCAATTTTTCGCTGGAGGTGGACTC
CGGCGTGCGTTTGTGCGTGTGCGGTCCCAACGGCACGGGTAAGTCCACGCTTTTACGCCTGCTGGCCGGGGTGGATGCCC
CGGACGGCGGCCGTGTCATCCTGCCGCGCGGTTGCCGCATGGGCTATGTGGAACAGGAGCTTTCAGAAGAAGCCCTGGAC
ACACCCCTGCTGACCTACGTGCTGGACGTGCTGCATGACTGGAGCGATTTTTGGGCGCAATGGGAAGATGCCGCCGCCAG
CAAGGACGAAGCCCTGCTGACCGAGCTTATGCACCGGCAGAGCGAGCTTGAAGCGCGCTACGGCTATAATCCCGAGCACC
GGGCCAAGGCTGTGCTTTCAGGACTGGGCTTTGCCGAGCGCAAGTGGCACCGCACCCTGCGCGAACTTTCGGGCGGCTGG
CGCGAGCGCGCCAAGCTGGCCCGTGTGCTTACCGCCGGGGCCGATGTACTCCTGCTGGACGAACCCACCAACCATCTGGA
TATGGAAGCCGTGGAGTGGCTGGAGTCCTTTCTGCTGGACTTCAAGGGCGCGCTGGTCTTTGTGGCGCACGACCGCCGCT
TTATGGACACGGTGGGCACGCATGTGCTTTACCTCGGCCTTTCGCGACCCGTATTCCGCAAGGCCACCTATACCCAGTTT
CTGACCCTTCAGGACGAGTATAACGCCCAGCGCGAACGCGAAGCCCGCGCCCTCAAGGACGAGCTTGACCGCAAAATGGC
CTTTGTGGAGCGCTTCCGCGCCAAGGCCACCAAGGCCCGTCAGGCCGGGTCGCGCCAGAAGATGGCGAAAAAGCTGGAAA
AAGAGCTGGAAGACTACCGGCCGGAACCCAAGCGCAAAGAGCTGAATTTCACCTGGCCCGAAGCACCGCATTCTGAAAAA
ATCGTGCTCTCTGCCGCAGACCTGGACTTTCACTTCAACGACGGCAAAAAAATGTGGCCGCCGCTGAGTTTCACCCTGTA
TCGCGGCCAGCGCATCGCCCTGGTAGGACACAACGGCTGCGGCAAGTCCACCCTGCTCAAACTGCTGGCAGGCAATCTTG
AGCGCTGCGGCGGCAATATGGTCACCTCGTCCCAGGTGCGGCTGGGCTACTATACCCAGCACCAGATGGACACCCTGCGC
GGCGACACCACAGTGCTTGGCGAAATCCGCCGCCTGTCCGACCCCCGCACCACAGAAGAAGAGCTTATGAGTGTGCTCGG
GCTGTTCATGCTGGGGCAGGAATACTTTGACCGTCAGGTCAGCGGCCTTTCAGGCGGCGAAAAAAGCCGTCTTGTGCTGG
CAAGCCTATTCCTGAAGCGCTGCAACTTTCTGCTGCTGGACGAACCCACCAACCATCTGGACCTTGAAAGCCGCGAGGCG
CTCGTATCGGCCCTGCAAAAATTCACAGGCACCCTGCTTATGGTGGCCCACGACCGCTGGCTGCTCTCTCAGGTGGGCGC
GGAAGCATGGGAGCTTGACAAAAGCGGCCTGACTGTGTTCTCGGATTTTACCGCATATGATGCCGAACGCCGCTCGCGCA
TGGCAGGTACGGGGCAAACGGCCCCGGCCGTTTCCGGCGGCGTTGCCTCCGGCCGGAACGCTTCGGGTGATCAGGCGCAG
GAGGCTTCGGCACAAAATCTTTCGCGCGAAGAGCAAAAACGCCTCAAACGCGAACAGGCCGAAAAGCGCAACGCCCTGCA
CAAGGAAATCAAGCCCCTGCAAAGCAAGTATGACGCCCTGGAAAAAGAACTTACCGGGGTGCTTGAAAAACAGGGCACGG
TGGAGGCCCAGCTGGCCGACCCCGAAGTCTACGCCGAGCACGAAAAGGCTGCGGAACTGCTGAAGAGTTTTGAAGCCTGC
AAAAAACGCGGCGAAGACATCTTTGAGGAAATGACCGCTCTTGACGAGCGCATGGAAGCCGTGCGCGCACGGTGGAATAC
AGAAGACTGA

Upstream 100 bases:

>100_bases
ACGGCAGCCGCATACGGCGCGAACTTGGTTTCACGCCGTGCATGAGCCTTGAGGCGGGAATGAAAGAAGCTGTAGAAGGC
TACCGCCGTGAGGGCTGGTT

Downstream 100 bases:

>100_bases
TCCAGGCTGAATACGGCGCATGGCCCGCCTGCGGTTCCGTCCACAGGCTCGGGGCCGCATGGCCGGGGTGCAGCAACGTG
CCTGCCGCTTGCAGATCCTG

Product: ABC transporter-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 669; Mature: 669

Protein sequence:

>669_residues
MKITIQELSKSFGGRDIFSNFSLEVDSGVRLCVCGPNGTGKSTLLRLLAGVDAPDGGRVILPRGCRMGYVEQELSEEALD
TPLLTYVLDVLHDWSDFWAQWEDAAASKDEALLTELMHRQSELEARYGYNPEHRAKAVLSGLGFAERKWHRTLRELSGGW
RERAKLARVLTAGADVLLLDEPTNHLDMEAVEWLESFLLDFKGALVFVAHDRRFMDTVGTHVLYLGLSRPVFRKATYTQF
LTLQDEYNAQREREARALKDELDRKMAFVERFRAKATKARQAGSRQKMAKKLEKELEDYRPEPKRKELNFTWPEAPHSEK
IVLSAADLDFHFNDGKKMWPPLSFTLYRGQRIALVGHNGCGKSTLLKLLAGNLERCGGNMVTSSQVRLGYYTQHQMDTLR
GDTTVLGEIRRLSDPRTTEEELMSVLGLFMLGQEYFDRQVSGLSGGEKSRLVLASLFLKRCNFLLLDEPTNHLDLESREA
LVSALQKFTGTLLMVAHDRWLLSQVGAEAWELDKSGLTVFSDFTAYDAERRSRMAGTGQTAPAVSGGVASGRNASGDQAQ
EASAQNLSREEQKRLKREQAEKRNALHKEIKPLQSKYDALEKELTGVLEKQGTVEAQLADPEVYAEHEKAAELLKSFEAC
KKRGEDIFEEMTALDERMEAVRARWNTED

Sequences:

>Translated_669_residues
MKITIQELSKSFGGRDIFSNFSLEVDSGVRLCVCGPNGTGKSTLLRLLAGVDAPDGGRVILPRGCRMGYVEQELSEEALD
TPLLTYVLDVLHDWSDFWAQWEDAAASKDEALLTELMHRQSELEARYGYNPEHRAKAVLSGLGFAERKWHRTLRELSGGW
RERAKLARVLTAGADVLLLDEPTNHLDMEAVEWLESFLLDFKGALVFVAHDRRFMDTVGTHVLYLGLSRPVFRKATYTQF
LTLQDEYNAQREREARALKDELDRKMAFVERFRAKATKARQAGSRQKMAKKLEKELEDYRPEPKRKELNFTWPEAPHSEK
IVLSAADLDFHFNDGKKMWPPLSFTLYRGQRIALVGHNGCGKSTLLKLLAGNLERCGGNMVTSSQVRLGYYTQHQMDTLR
GDTTVLGEIRRLSDPRTTEEELMSVLGLFMLGQEYFDRQVSGLSGGEKSRLVLASLFLKRCNFLLLDEPTNHLDLESREA
LVSALQKFTGTLLMVAHDRWLLSQVGAEAWELDKSGLTVFSDFTAYDAERRSRMAGTGQTAPAVSGGVASGRNASGDQAQ
EASAQNLSREEQKRLKREQAEKRNALHKEIKPLQSKYDALEKELTGVLEKQGTVEAQLADPEVYAEHEKAAELLKSFEAC
KKRGEDIFEEMTALDERMEAVRARWNTED
>Mature_669_residues
MKITIQELSKSFGGRDIFSNFSLEVDSGVRLCVCGPNGTGKSTLLRLLAGVDAPDGGRVILPRGCRMGYVEQELSEEALD
TPLLTYVLDVLHDWSDFWAQWEDAAASKDEALLTELMHRQSELEARYGYNPEHRAKAVLSGLGFAERKWHRTLRELSGGW
RERAKLARVLTAGADVLLLDEPTNHLDMEAVEWLESFLLDFKGALVFVAHDRRFMDTVGTHVLYLGLSRPVFRKATYTQF
LTLQDEYNAQREREARALKDELDRKMAFVERFRAKATKARQAGSRQKMAKKLEKELEDYRPEPKRKELNFTWPEAPHSEK
IVLSAADLDFHFNDGKKMWPPLSFTLYRGQRIALVGHNGCGKSTLLKLLAGNLERCGGNMVTSSQVRLGYYTQHQMDTLR
GDTTVLGEIRRLSDPRTTEEELMSVLGLFMLGQEYFDRQVSGLSGGEKSRLVLASLFLKRCNFLLLDEPTNHLDLESREA
LVSALQKFTGTLLMVAHDRWLLSQVGAEAWELDKSGLTVFSDFTAYDAERRSRMAGTGQTAPAVSGGVASGRNASGDQAQ
EASAQNLSREEQKRLKREQAEKRNALHKEIKPLQSKYDALEKELTGVLEKQGTVEAQLADPEVYAEHEKAAELLKSFEAC
KKRGEDIFEEMTALDERMEAVRARWNTED

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=538, Percent_Identity=33.8289962825279, Blast_Score=270, Evalue=4e-72,
Organism=Homo sapiens, GI27881506, Length=543, Percent_Identity=32.4125230202578, Blast_Score=240, Evalue=3e-63,
Organism=Homo sapiens, GI10947137, Length=543, Percent_Identity=32.4125230202578, Blast_Score=240, Evalue=3e-63,
Organism=Homo sapiens, GI69354671, Length=545, Percent_Identity=30.4587155963303, Blast_Score=216, Evalue=8e-56,
Organism=Homo sapiens, GI10947135, Length=545, Percent_Identity=30.4587155963303, Blast_Score=216, Evalue=8e-56,
Organism=Homo sapiens, GI4506341, Length=351, Percent_Identity=25.0712250712251, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1789751, Length=630, Percent_Identity=33.4920634920635, Blast_Score=312, Evalue=4e-86,
Organism=Escherichia coli, GI1787041, Length=526, Percent_Identity=31.7490494296578, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI1787182, Length=647, Percent_Identity=29.3663060278207, Blast_Score=251, Evalue=2e-67,
Organism=Escherichia coli, GI2367384, Length=540, Percent_Identity=31.8518518518519, Blast_Score=238, Evalue=1e-63,
Organism=Escherichia coli, GI87081834, Length=200, Percent_Identity=31.5, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI87081791, Length=182, Percent_Identity=35.1648351648352, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI1788165, Length=213, Percent_Identity=28.169014084507, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1787758, Length=173, Percent_Identity=28.3236994219653, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1787500, Length=223, Percent_Identity=24.2152466367713, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1787547, Length=162, Percent_Identity=28.3950617283951, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1788644, Length=235, Percent_Identity=28.936170212766, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=531, Percent_Identity=34.2749529190207, Blast_Score=255, Evalue=4e-68,
Organism=Caenorhabditis elegans, GI17555318, Length=517, Percent_Identity=32.8820116054159, Blast_Score=242, Evalue=4e-64,
Organism=Caenorhabditis elegans, GI17559834, Length=558, Percent_Identity=30.6451612903226, Blast_Score=232, Evalue=4e-61,
Organism=Caenorhabditis elegans, GI71992285, Length=235, Percent_Identity=29.7872340425532, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17542146, Length=180, Percent_Identity=28.8888888888889, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17569143, Length=220, Percent_Identity=27.2727272727273, Blast_Score=66, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6321121, Length=547, Percent_Identity=32.9067641681901, Blast_Score=253, Evalue=7e-68,
Organism=Saccharomyces cerevisiae, GI6320874, Length=524, Percent_Identity=31.1068702290076, Blast_Score=227, Evalue=4e-60,
Organism=Saccharomyces cerevisiae, GI6325030, Length=400, Percent_Identity=28.25, Blast_Score=132, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6323278, Length=392, Percent_Identity=27.2959183673469, Blast_Score=128, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6324314, Length=391, Percent_Identity=26.3427109974425, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24666836, Length=517, Percent_Identity=33.8491295938104, Blast_Score=279, Evalue=4e-75,
Organism=Drosophila melanogaster, GI24641342, Length=568, Percent_Identity=30.6338028169014, Blast_Score=246, Evalue=5e-65,
Organism=Drosophila melanogaster, GI24642252, Length=519, Percent_Identity=31.7919075144509, Blast_Score=244, Evalue=2e-64,
Organism=Drosophila melanogaster, GI18859989, Length=519, Percent_Identity=31.7919075144509, Blast_Score=244, Evalue=2e-64,
Organism=Drosophila melanogaster, GI24643394, Length=183, Percent_Identity=29.5081967213115, Blast_Score=68, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 75551; Mature: 75551

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITIQELSKSFGGRDIFSNFSLEVDSGVRLCVCGPNGTGKSTLLRLLAGVDAPDGGRVI
CEEEHHHHHHHCCCCHHHCCCCEEECCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCEEE
LPRGCRMGYVEQELSEEALDTPLLTYVLDVLHDWSDFWAQWEDAAASKDEALLTELMHRQ
ECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
SELEARYGYNPEHRAKAVLSGLGFAERKWHRTLRELSGGWRERAKLARVLTAGADVLLLD
HHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEC
EPTNHLDMEAVEWLESFLLDFKGALVFVAHDRRFMDTVGTHVLYLGLSRPVFRKATYTQF
CCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHEEECCCCHHHHHHHHHHH
LTLQDEYNAQREREARALKDELDRKMAFVERFRAKATKARQAGSRQKMAKKLEKELEDYR
EEECHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
PEPKRKELNFTWPEAPHSEKIVLSAADLDFHFNDGKKMWPPLSFTLYRGQRIALVGHNGC
CCCCCCCCCCCCCCCCCCCEEEEEEECCEEEECCCCCCCCCCEEEEECCCEEEEEECCCC
GKSTLLKLLAGNLERCGGNMVTSSQVRLGYYTQHQMDTLRGDTTVLGEIRRLSDPRTTEE
CHHHHHHHHHCCHHHCCCCCEECCCEEEEEEHHHHHHHHCCCHHHHHHHHHCCCCCCCHH
ELMSVLGLFMLGQEYFDRQVSGLSGGEKSRLVLASLFLKRCNFLLLDEPTNHLDLESREA
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHH
LVSALQKFTGTLLMVAHDRWLLSQVGAEAWELDKSGLTVFSDFTAYDAERRSRMAGTGQT
HHHHHHHHHCEEEEEECCHHHHHHHCCHHHHCCCCCCEEEEHHHHHHHHHHHHHCCCCCC
APAVSGGVASGRNASGDQAQEASAQNLSREEQKRLKREQAEKRNALHKEIKPLQSKYDAL
CCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKELTGVLEKQGTVEAQLADPEVYAEHEKAAELLKSFEACKKRGEDIFEEMTALDERMEA
HHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VRARWNTED
HHHHCCCCC
>Mature Secondary Structure
MKITIQELSKSFGGRDIFSNFSLEVDSGVRLCVCGPNGTGKSTLLRLLAGVDAPDGGRVI
CEEEHHHHHHHCCCCHHHCCCCEEECCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCEEE
LPRGCRMGYVEQELSEEALDTPLLTYVLDVLHDWSDFWAQWEDAAASKDEALLTELMHRQ
ECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
SELEARYGYNPEHRAKAVLSGLGFAERKWHRTLRELSGGWRERAKLARVLTAGADVLLLD
HHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEC
EPTNHLDMEAVEWLESFLLDFKGALVFVAHDRRFMDTVGTHVLYLGLSRPVFRKATYTQF
CCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHEEECCCCHHHHHHHHHHH
LTLQDEYNAQREREARALKDELDRKMAFVERFRAKATKARQAGSRQKMAKKLEKELEDYR
EEECHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
PEPKRKELNFTWPEAPHSEKIVLSAADLDFHFNDGKKMWPPLSFTLYRGQRIALVGHNGC
CCCCCCCCCCCCCCCCCCCEEEEEEECCEEEECCCCCCCCCCEEEEECCCEEEEEECCCC
GKSTLLKLLAGNLERCGGNMVTSSQVRLGYYTQHQMDTLRGDTTVLGEIRRLSDPRTTEE
CHHHHHHHHHCCHHHCCCCCEECCCEEEEEEHHHHHHHHCCCHHHHHHHHHCCCCCCCHH
ELMSVLGLFMLGQEYFDRQVSGLSGGEKSRLVLASLFLKRCNFLLLDEPTNHLDLESREA
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHH
LVSALQKFTGTLLMVAHDRWLLSQVGAEAWELDKSGLTVFSDFTAYDAERRSRMAGTGQT
HHHHHHHHHCEEEEEECCHHHHHHHCCHHHHCCCCCCEEEEHHHHHHHHHHHHHCCCCCC
APAVSGGVASGRNASGDQAQEASAQNLSREEQKRLKREQAEKRNALHKEIKPLQSKYDAL
CCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKELTGVLEKQGTVEAQLADPEVYAEHEKAAELLKSFEACKKRGEDIFEEMTALDERMEA
HHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VRARWNTED
HHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]