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The map label for this gene is dcrA [H]

Identifier: 220905411

GI number: 220905411

Start: 2590341

End: 2591924

Strand: Direct

Name: dcrA [H]

Synonym: Ddes_2149

Alternate gene names: 220905411

Gene position: 2590341-2591924 (Clockwise)

Preceding gene: 220905410

Following gene: 220905413

Centisome position: 90.15

GC content: 58.21

Gene sequence:

>1584_bases
ATGAATCTCACCCTCAGCTTTCGCATTACTGTATTTTTCATCATTGCCCTTGTGCTGGCCTGTGCGGCCATGCTGACCGG
CTTCAAGCTTGCCCTGGGCGACGGCCTGAGCGCCGCAGCCATGTGGAAAGCCCTGCTGTTCGGCGCGGGGAGCATTGCGA
TTCTGGGCGTCGTCGGCGCAATATTCATTAACGGCAGGCTCGCGCCCATCCGCAAATGCGTTCTCTACGCCGAAGCCATC
GCCGCCGGGCATCAAGAGGCCAGGCTTGACGTGTACCGCACCGACTGCCTGGGCCATCTGGCTGAGTCACTGCGCATCAT
GGTCGCCAAGCTGGAAAGCCAGGCACATTGGTACGAGGGCATACTGAACACCCTGCCCATGTCGGTTTCCGTTACGGACA
ACGACATGATCTGGACATTCTGCAATACCTATGCTCTCGAAACCATGAATAAAACATGTCAAAACGATGTGGTTGGCAAA
CATTGCTCGGAAAAGCAAGGCAATATCTGCAATACCCCCGAATGCGGCATCGAGCAGCTGCGCCTTGGCAATAAAAAGGT
CATCAACCACATGCCCAACGGCAAGACCATGCAGATCATGCTGGACTACTTGAAGGATGCAGAAGGCAAAACCATTGGGC
ATGTGGAAATAGGCGAAGATATCACTGAAAAAGTCATGCTTGAAAAACAGGCCGCCGAGGCCGCGCACAAGGCAAGAGTG
CACACCGTCACACAGCTTGAAGACGTGGTGGCGCACCTGCAGCATGCGGCCGACACGCTCAATGCTTCACTTGGTGACGT
GCGTGACAAGGCGGGCGTTGCCGCCGGGCGCATGGCCGAAACCGCCACCGCCATGAACGAAATGAACGCCACCGTACTTG
AGGTGGCCCATAATGCCGAAGGCGCCGCCAAGGCCGCAACATCCGTACAGGGACATGCCCAGGAAGGCGCGGGCATTGTG
CTGCGCACCATCCAGAGCATGCAGAGCGTGCAGCAGCAGTCCAGCGGACTCATGGGTGACATGGGCGGCCTTGACAAACA
GGCCAAGGATATCGGTGCGGTGCTCACCCTTATCCGCGACATTGCGGATCAGACCAACCTGCTCGCCCTCAACGCAGCCA
TTGAGGCCGCCCGCGCAGGCGAGGCAGGGCGTGGCTTTGCCGTAGTGGCCGACGAAGTGCGTAAACTGGCAGAAAAAACC
ATGAGTGCCACCCAGGAGGTGGAAACCGCCATTGCCGCCATTCAGGACGGCACTGGCAAAAGCGCCACCACGGTTAACAA
TACCGTGTCAGCCATTGACGAGGTGAGTCGCATGGCCGAAGAGTCAGGACAGTCGCTGGAGCAGATTTCAGCTCTGGCCG
GGGATTCCAGCTCGCGGGTTTCTGCCATTGCCGCCGCGGCTACGGAGCAGTCCGCCGCCTCGGAAGAAATCAACCGGCAT
ATAGCCGAAGTCAACAGCCTGAGCGCCCACATTGCGGAAGCGATGGATATGGCGGCACGCCAGGTCAACGACATGGCCGG
TCAGGTCAGCGTTGTCACAGGCATTCTTGACGCCATACGCAAGGAAGATCACACACAACAGTAA

Upstream 100 bases:

>100_bases
GACCAGAACCCGCGCGACACAGCACCGCAGCCATGGGTACACCTGAACGTATTTTCCGCCACCTGTGACTTCGGGAGCGG
CTATCTAAGGAAGAACCCTT

Downstream 100 bases:

>100_bases
GGCTGCACGGGCGCGCACAGCGCGTACCCCATGCAAGCCTCGCAGCCCGACGCCCTTGACATCGGGCGCGGAAAAAGCCG
CCGGACCACAATCCGGCGGC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 527; Mature: 527

Protein sequence:

>527_residues
MNLTLSFRITVFFIIALVLACAAMLTGFKLALGDGLSAAAMWKALLFGAGSIAILGVVGAIFINGRLAPIRKCVLYAEAI
AAGHQEARLDVYRTDCLGHLAESLRIMVAKLESQAHWYEGILNTLPMSVSVTDNDMIWTFCNTYALETMNKTCQNDVVGK
HCSEKQGNICNTPECGIEQLRLGNKKVINHMPNGKTMQIMLDYLKDAEGKTIGHVEIGEDITEKVMLEKQAAEAAHKARV
HTVTQLEDVVAHLQHAADTLNASLGDVRDKAGVAAGRMAETATAMNEMNATVLEVAHNAEGAAKAATSVQGHAQEGAGIV
LRTIQSMQSVQQQSSGLMGDMGGLDKQAKDIGAVLTLIRDIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAEKT
MSATQEVETAIAAIQDGTGKSATTVNNTVSAIDEVSRMAEESGQSLEQISALAGDSSSRVSAIAAAATEQSAASEEINRH
IAEVNSLSAHIAEAMDMAARQVNDMAGQVSVVTGILDAIRKEDHTQQ

Sequences:

>Translated_527_residues
MNLTLSFRITVFFIIALVLACAAMLTGFKLALGDGLSAAAMWKALLFGAGSIAILGVVGAIFINGRLAPIRKCVLYAEAI
AAGHQEARLDVYRTDCLGHLAESLRIMVAKLESQAHWYEGILNTLPMSVSVTDNDMIWTFCNTYALETMNKTCQNDVVGK
HCSEKQGNICNTPECGIEQLRLGNKKVINHMPNGKTMQIMLDYLKDAEGKTIGHVEIGEDITEKVMLEKQAAEAAHKARV
HTVTQLEDVVAHLQHAADTLNASLGDVRDKAGVAAGRMAETATAMNEMNATVLEVAHNAEGAAKAATSVQGHAQEGAGIV
LRTIQSMQSVQQQSSGLMGDMGGLDKQAKDIGAVLTLIRDIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAEKT
MSATQEVETAIAAIQDGTGKSATTVNNTVSAIDEVSRMAEESGQSLEQISALAGDSSSRVSAIAAAATEQSAASEEINRH
IAEVNSLSAHIAEAMDMAARQVNDMAGQVSVVTGILDAIRKEDHTQQ
>Mature_527_residues
MNLTLSFRITVFFIIALVLACAAMLTGFKLALGDGLSAAAMWKALLFGAGSIAILGVVGAIFINGRLAPIRKCVLYAEAI
AAGHQEARLDVYRTDCLGHLAESLRIMVAKLESQAHWYEGILNTLPMSVSVTDNDMIWTFCNTYALETMNKTCQNDVVGK
HCSEKQGNICNTPECGIEQLRLGNKKVINHMPNGKTMQIMLDYLKDAEGKTIGHVEIGEDITEKVMLEKQAAEAAHKARV
HTVTQLEDVVAHLQHAADTLNASLGDVRDKAGVAAGRMAETATAMNEMNATVLEVAHNAEGAAKAATSVQGHAQEGAGIV
LRTIQSMQSVQQQSSGLMGDMGGLDKQAKDIGAVLTLIRDIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAEKT
MSATQEVETAIAAIQDGTGKSATTVNNTVSAIDEVSRMAEESGQSLEQISALAGDSSSRVSAIAAAATEQSAASEEINRH
IAEVNSLSAHIAEAMDMAARQVNDMAGQVSVVTGILDAIRKEDHTQQ

Specific function: Receptor For The Attractant L-Serine And Related Amino Acids. Is Also Responsible For Chemotaxis Away From A Wide Range Of Repellents, Including Leucine, Indole, And Weak Acids. Chemotactic-Signal Transducers Respond To Changes In The Concentration Of At

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=257, Percent_Identity=31.9066147859922, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1788195, Length=255, Percent_Identity=31.7647058823529, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787690, Length=302, Percent_Identity=30.4635761589404, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1788194, Length=260, Percent_Identity=30.7692307692308, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1789453, Length=256, Percent_Identity=28.125, Blast_Score=89, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF00989 PAS [H]

EC number: NA

Molecular weight: Translated: 55761; Mature: 55761

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLTLSFRITVFFIIALVLACAAMLTGFKLALGDGLSAAAMWKALLFGAGSIAILGVVGA
CCEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHH
IFINGRLAPIRKCVLYAEAIAAGHQEARLDVYRTDCLGHLAESLRIMVAKLESQAHWYEG
HHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILNTLPMSVSVTDNDMIWTFCNTYALETMNKTCQNDVVGKHCSEKQGNICNTPECGIEQL
HHHHCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
RLGNKKVINHMPNGKTMQIMLDYLKDAEGKTIGHVEIGEDITEKVMLEKQAAEAAHKARV
HCCCHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
HTVTQLEDVVAHLQHAADTLNASLGDVRDKAGVAAGRMAETATAMNEMNATVLEVAHNAE
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHCCC
GAAKAATSVQGHAQEGAGIVLRTIQSMQSVQQQSSGLMGDMGGLDKQAKDIGAVLTLIRD
CHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
IADQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAEKTMSATQEVETAIAAIQDGTGK
HHCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SATTVNNTVSAIDEVSRMAEESGQSLEQISALAGDSSSRVSAIAAAATEQSAASEEINRH
CCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
IAEVNSLSAHIAEAMDMAARQVNDMAGQVSVVTGILDAIRKEDHTQQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNLTLSFRITVFFIIALVLACAAMLTGFKLALGDGLSAAAMWKALLFGAGSIAILGVVGA
CCEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHH
IFINGRLAPIRKCVLYAEAIAAGHQEARLDVYRTDCLGHLAESLRIMVAKLESQAHWYEG
HHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILNTLPMSVSVTDNDMIWTFCNTYALETMNKTCQNDVVGKHCSEKQGNICNTPECGIEQL
HHHHCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
RLGNKKVINHMPNGKTMQIMLDYLKDAEGKTIGHVEIGEDITEKVMLEKQAAEAAHKARV
HCCCHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
HTVTQLEDVVAHLQHAADTLNASLGDVRDKAGVAAGRMAETATAMNEMNATVLEVAHNAE
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHCCC
GAAKAATSVQGHAQEGAGIVLRTIQSMQSVQQQSSGLMGDMGGLDKQAKDIGAVLTLIRD
CHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
IADQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAEKTMSATQEVETAIAAIQDGTGK
HHCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SATTVNNTVSAIDEVSRMAEESGQSLEQISALAGDSSSRVSAIAAAATEQSAASEEINRH
CCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
IAEVNSLSAHIAEAMDMAARQVNDMAGQVSVVTGILDAIRKEDHTQQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1548224 [H]