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The map label for this gene is gufA [H]

Identifier: 220905410

GI number: 220905410

Start: 2588934

End: 2589764

Strand: Direct

Name: gufA [H]

Synonym: Ddes_2148

Alternate gene names: 220905410

Gene position: 2588934-2589764 (Clockwise)

Preceding gene: 220905409

Following gene: 220905411

Centisome position: 90.1

GC content: 60.29

Gene sequence:

>831_bases
ATGGACCCGGCCGTTTCTTCCGCTATCCAGCATCCCGTGGCACAAGCCACTGTGGCTGGTCTGCTGTCATGGCTTTCCGT
CAGCCTCGGCGCGGCATTCATATTTACCCGGCGGGAATTTTCACGCAAAGCCATGGACTGTCTTCTGGGCGCAGCCGGGG
GCATGATGCTGGGCGCGTCCTTCTTCGGCCTGCTGCAACCGGCCATGGAACTGACCTCTCACATGGGGCGTACGGGCTTC
ATCCCTGTAGTGTTCGGGCTGCTGCTGGGCGCGGGTTTTCTGCTAATGCTCGACCGTGTTCTGCCCCACCTGCACCTTGT
ACAGGATACCACCGAGGGCATCTCGACACGCTGGCGGCGCAGTGTTCTGCTTGTTACGGCCATGGCCCTGCACCATATTC
CCGAAGGGCTGGCCATCGGGGTAGGTTATGGGGCAGCCGCTGCGGAAAGCGGCATGGCTACAGGCATTGAAAGCCTCGGC
ATGAGCACGGCCCTGGTGCTTACCGCGTCCATCATGCTGCAAAACCTGCCCGAGGGTATGGTAGTATCCACCGCCTTGCG
GGCCGAAGGCTATTCAGCAAAAAAATCCTTCTTTTATGGTGTACTCTCCGGCGTGACCGCCCCCATCGGGGCCATACCGG
GGGCCATGGCCGCAGGGGTAACTGCGGGCATTCTGCCCGTGGCTCTGGCCTTTGCCGCAGGGGCCATGATCTATGTGGTC
TTTGAAGAGGTCATTCCTGAAGCCAACGCCTCGGGCAATGGCAATGCCGCTTCTCTCTCCTGTATTTTCGGGGTTTGTCT
GGTTATTGCGCTCACCACCCTGCTGGGTTGA

Upstream 100 bases:

>100_bases
GGACGGCTTGGCCCACGGCAGCACAGGCGCATGGCGCACCGGCGCACCGCGCACCGCGCACATTCAGACAATAGATATCC
CCACATTGCAGGAGGTTCTG

Downstream 100 bases:

>100_bases
CCGGCCTTTTCCCTTTAAAAAAACTAAGCAGCGATGTTGCAGCTCCTGCCTGAGCCGGGTTCTTCTGCGGAACCCGGCTC
TGCCTTGTTCGCATGGGTTC

Product: zinc/iron permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MDPAVSSAIQHPVAQATVAGLLSWLSVSLGAAFIFTRREFSRKAMDCLLGAAGGMMLGASFFGLLQPAMELTSHMGRTGF
IPVVFGLLLGAGFLLMLDRVLPHLHLVQDTTEGISTRWRRSVLLVTAMALHHIPEGLAIGVGYGAAAAESGMATGIESLG
MSTALVLTASIMLQNLPEGMVVSTALRAEGYSAKKSFFYGVLSGVTAPIGAIPGAMAAGVTAGILPVALAFAAGAMIYVV
FEEVIPEANASGNGNAASLSCIFGVCLVIALTTLLG

Sequences:

>Translated_276_residues
MDPAVSSAIQHPVAQATVAGLLSWLSVSLGAAFIFTRREFSRKAMDCLLGAAGGMMLGASFFGLLQPAMELTSHMGRTGF
IPVVFGLLLGAGFLLMLDRVLPHLHLVQDTTEGISTRWRRSVLLVTAMALHHIPEGLAIGVGYGAAAAESGMATGIESLG
MSTALVLTASIMLQNLPEGMVVSTALRAEGYSAKKSFFYGVLSGVTAPIGAIPGAMAAGVTAGILPVALAFAAGAMIYVV
FEEVIPEANASGNGNAASLSCIFGVCLVIALTTLLG
>Mature_276_residues
MDPAVSSAIQHPVAQATVAGLLSWLSVSLGAAFIFTRREFSRKAMDCLLGAAGGMMLGASFFGLLQPAMELTSHMGRTGF
IPVVFGLLLGAGFLLMLDRVLPHLHLVQDTTEGISTRWRRSVLLVTAMALHHIPEGLAIGVGYGAAAAESGMATGIESLG
MSTALVLTASIMLQNLPEGMVVSTALRAEGYSAKKSFFYGVLSGVTAPIGAIPGAMAAGVTAGILPVALAFAAGAMIYVV
FEEVIPEANASGNGNAASLSCIFGVCLVIALTTLLG

Specific function: Mediates Zinc Uptake. May Also Transport Other Divalent Cations Such As Copper And Cadmium Ions. [C]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI229577422, Length=161, Percent_Identity=44.7204968944099, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI229577418, Length=161, Percent_Identity=44.7204968944099, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17507805, Length=323, Percent_Identity=36.5325077399381, Blast_Score=182, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24652846, Length=169, Percent_Identity=43.1952662721894, Blast_Score=130, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 28241; Mature: 28241

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPAVSSAIQHPVAQATVAGLLSWLSVSLGAAFIFTRREFSRKAMDCLLGAAGGMMLGAS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
FFGLLQPAMELTSHMGRTGFIPVVFGLLLGAGFLLMLDRVLPHLHLVQDTTEGISTRWRR
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVLLVTAMALHHIPEGLAIGVGYGAAAAESGMATGIESLGMSTALVLTASIMLQNLPEGM
HHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCH
VVSTALRAEGYSAKKSFFYGVLSGVTAPIGAIPGAMAAGVTAGILPVALAFAAGAMIYVV
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEEVIPEANASGNGNAASLSCIFGVCLVIALTTLLG
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDPAVSSAIQHPVAQATVAGLLSWLSVSLGAAFIFTRREFSRKAMDCLLGAAGGMMLGAS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
FFGLLQPAMELTSHMGRTGFIPVVFGLLLGAGFLLMLDRVLPHLHLVQDTTEGISTRWRR
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVLLVTAMALHHIPEGLAIGVGYGAAAAESGMATGIESLGMSTALVLTASIMLQNLPEGM
HHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCH
VVSTALRAEGYSAKKSFFYGVLSGVTAPIGAIPGAMAAGVTAGILPVALAFAAGAMIYVV
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEEVIPEANASGNGNAASLSCIFGVCLVIALTTLLG
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934835 [H]