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The map label for this gene is hdrA2 [H]

Identifier: 220905362

GI number: 220905362

Start: 2529180

End: 2531141

Strand: Direct

Name: hdrA2 [H]

Synonym: Ddes_2100

Alternate gene names: 220905362

Gene position: 2529180-2531141 (Clockwise)

Preceding gene: 220905361

Following gene: 220905363

Centisome position: 88.02

GC content: 59.43

Gene sequence:

>1962_bases
ATGAGAATAGGCGTTTTCGTCTGCCATTGCGGCAGCAATATCGGCGGCACCGTTGACTGCGCCAAGGTGGCTGAGATTGC
CCGCACCTACCCTGACGTGGTGTACGCCGACGACCCCATGTACACCTGTGCCGAACCCGGCCAGGCAGCCATTGAGGCAG
CCATTCACGAGCACAAGCTTGACGGCGTTGTGGTGGCTTCCTGTTCGCCCCGCATGCACGAGCCGACCTTCCGCCGCACG
GTGGAACGCGCGGGGCTCAACCGCTACATGCTCGAAATGGCGAATATTCGCGAGCATGTCTCGTGGATTGGCCGCGACAA
GGAAGCCAATACCAACAAATCCGCCGAACTAGTTTTGCTGGCGGTTGAAAAGCTGCGCAACAACAAGCCGCTGCTCGCCA
AAAGCTTTGACGTCAACAAGCGCGTGCTCGTCATCGGCGGCGGCGTGGCGGGCATTCAGGCCGCCCTTGACTGCGCCGAC
GGCGGCGTGCCCGTGGTGCTTGTGGAGCGTGATGCCACCATCGGCGGCAAAATGGCCAAGCTGGACAAGACCTTTCCCAC
GGTGGACTGCTCGGCCTGCATTCTCGGCCCCAAGATGGTCGACGTGGCCCAGCACTCCAACATCACGCTGTATGCTTATT
CCGAGGTGGAAGACATTTCGGGCTATGTGGGCAACTTTACGGTGAAAATCCGCAAAAGGGCCACCTATGTAGACTGGAGC
CTCTGCACCGGCTGCGGAGCCTGCACAGAAAAATGCCCCAGCAAAAAAACGCCTGACGCCTTTAACGAAGAGATCAGCAA
CACCACGGCCATCACCATTGCCTTTCCGCAGGCCATCCCCAAAAAGGCCGTCATCAACGCCGGGCACTGCCGCCAGTTCA
TCAAGGGCAAGTGCGGCGTATGCGCCAAAATATGCCCCACCGGGGCCATCAAGTATGACATGGAAGACGAGATCATAACC
GAAGAGGTGGGCAGCATCGTGGCCGCCACCGGCTATGACCTCATGGACTGGACCGTGTACCAGGAATATGGCGGCGGCGC
TTACCCCGACGTTATCACGTCCCTGCAGTACGAGCGGCTGCTCAATGCCTCCGGTCCCACTGCCGGGCATATCAAACGCC
CCTCGGACGGCAAGGAACCCAAAAACATCGTTTTCGTGCAGTGTGTCGGCTCGCGCGACAAATCCATCGGGCGGCCCTAC
TGCTCCGGCTTCTGCTGCATGTATACGGCCAAGCAGGCCATCCTGACCAAGGATCACATTCCGGATTCCCAGTCCTATGT
CTTCTATATGGACATCCGCGCCGCAGGCAAGATGTACGACGAGTTTACCCGCCGCACCATGGAAGAATACGGTACGGAAT
ACATCCGCGGGCGCGTCTCGCAGATATACCCCGATGGTCAGGGCCAGCTCGTGGTTATGGGCGTAGACACGCTTATGGGG
CAGGCCATTGAAATCAAGGCCGACCTTGTGGTTCTGGCTGTAGGTATCGAGGCCAGCAAGGGCGCACCTCAGCTGGCTGA
AAAGCTGCGTATTTCATACGACAGCTACGGCTTTTTTATGGAAAGCCACGTCAAGCTCAAGCCTGTAGAAACCAATACCG
CCGGTGTGTATCTGGCGGGCGTGTGCCAGGGGACCAAGGATATTCCCGCTTCCGTGGCCCAGGGTTCGGCTGCGGCCGCC
AAGGTGCTGGCCCTCTTTGCCAAAGACAAGCTGGAAAGCGACCCGCAGATCGCCCAGGTGGACATGCGCCGCTGCGTCAA
CTGCGGCAAGTGCATCCAGTGCTGCCCCTTCGGAGCCATCAAGGAAGTGGAAGTCCGGGGCGAAGGTAAGGCCCAGGTTA
TTGAAACCGTGTGCCAGGGCTGCGGGCTTTGCACGGCCACCTGCCCCCAGGGGGCCATCCAGCTTTCACACGCCACAGAC
AACCAGATTCTTGCGGAGGTTAACGCGCTATGCCAGCTTTAG

Upstream 100 bases:

>100_bases
TTAACAAACTGCGCGTCAGCCCTGACGGCCTCATCCGCAAGCTGGACGAACTCCGGCGCAATTCCGCCGCCGCAGACAAG
GCCGCTGAAGGAGGCAGGTC

Downstream 100 bases:

>100_bases
AAGGCAAAGAACTGCGGATTGTGGGTTTTCTCTGCAACTGGTGCTCCTATGGCGGCGCCGACACAGCCGGTGTGGCCCGC
GCCACCCAGCCCACAGATCT

Product: 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 653; Mature: 653

Protein sequence:

>653_residues
MRIGVFVCHCGSNIGGTVDCAKVAEIARTYPDVVYADDPMYTCAEPGQAAIEAAIHEHKLDGVVVASCSPRMHEPTFRRT
VERAGLNRYMLEMANIREHVSWIGRDKEANTNKSAELVLLAVEKLRNNKPLLAKSFDVNKRVLVIGGGVAGIQAALDCAD
GGVPVVLVERDATIGGKMAKLDKTFPTVDCSACILGPKMVDVAQHSNITLYAYSEVEDISGYVGNFTVKIRKRATYVDWS
LCTGCGACTEKCPSKKTPDAFNEEISNTTAITIAFPQAIPKKAVINAGHCRQFIKGKCGVCAKICPTGAIKYDMEDEIIT
EEVGSIVAATGYDLMDWTVYQEYGGGAYPDVITSLQYERLLNASGPTAGHIKRPSDGKEPKNIVFVQCVGSRDKSIGRPY
CSGFCCMYTAKQAILTKDHIPDSQSYVFYMDIRAAGKMYDEFTRRTMEEYGTEYIRGRVSQIYPDGQGQLVVMGVDTLMG
QAIEIKADLVVLAVGIEASKGAPQLAEKLRISYDSYGFFMESHVKLKPVETNTAGVYLAGVCQGTKDIPASVAQGSAAAA
KVLALFAKDKLESDPQIAQVDMRRCVNCGKCIQCCPFGAIKEVEVRGEGKAQVIETVCQGCGLCTATCPQGAIQLSHATD
NQILAEVNALCQL

Sequences:

>Translated_653_residues
MRIGVFVCHCGSNIGGTVDCAKVAEIARTYPDVVYADDPMYTCAEPGQAAIEAAIHEHKLDGVVVASCSPRMHEPTFRRT
VERAGLNRYMLEMANIREHVSWIGRDKEANTNKSAELVLLAVEKLRNNKPLLAKSFDVNKRVLVIGGGVAGIQAALDCAD
GGVPVVLVERDATIGGKMAKLDKTFPTVDCSACILGPKMVDVAQHSNITLYAYSEVEDISGYVGNFTVKIRKRATYVDWS
LCTGCGACTEKCPSKKTPDAFNEEISNTTAITIAFPQAIPKKAVINAGHCRQFIKGKCGVCAKICPTGAIKYDMEDEIIT
EEVGSIVAATGYDLMDWTVYQEYGGGAYPDVITSLQYERLLNASGPTAGHIKRPSDGKEPKNIVFVQCVGSRDKSIGRPY
CSGFCCMYTAKQAILTKDHIPDSQSYVFYMDIRAAGKMYDEFTRRTMEEYGTEYIRGRVSQIYPDGQGQLVVMGVDTLMG
QAIEIKADLVVLAVGIEASKGAPQLAEKLRISYDSYGFFMESHVKLKPVETNTAGVYLAGVCQGTKDIPASVAQGSAAAA
KVLALFAKDKLESDPQIAQVDMRRCVNCGKCIQCCPFGAIKEVEVRGEGKAQVIETVCQGCGLCTATCPQGAIQLSHATD
NQILAEVNALCQL
>Mature_653_residues
MRIGVFVCHCGSNIGGTVDCAKVAEIARTYPDVVYADDPMYTCAEPGQAAIEAAIHEHKLDGVVVASCSPRMHEPTFRRT
VERAGLNRYMLEMANIREHVSWIGRDKEANTNKSAELVLLAVEKLRNNKPLLAKSFDVNKRVLVIGGGVAGIQAALDCAD
GGVPVVLVERDATIGGKMAKLDKTFPTVDCSACILGPKMVDVAQHSNITLYAYSEVEDISGYVGNFTVKIRKRATYVDWS
LCTGCGACTEKCPSKKTPDAFNEEISNTTAITIAFPQAIPKKAVINAGHCRQFIKGKCGVCAKICPTGAIKYDMEDEIIT
EEVGSIVAATGYDLMDWTVYQEYGGGAYPDVITSLQYERLLNASGPTAGHIKRPSDGKEPKNIVFVQCVGSRDKSIGRPY
CSGFCCMYTAKQAILTKDHIPDSQSYVFYMDIRAAGKMYDEFTRRTMEEYGTEYIRGRVSQIYPDGQGQLVVMGVDTLMG
QAIEIKADLVVLAVGIEASKGAPQLAEKLRISYDSYGFFMESHVKLKPVETNTAGVYLAGVCQGTKDIPASVAQGSAAAA
KVLALFAKDKLESDPQIAQVDMRRCVNCGKCIQCCPFGAIKEVEVRGEGKAQVIETVCQGCGLCTATCPQGAIQLSHATD
NQILAEVNALCQL

Specific function: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). May act as the catalytic subunit [H]

COG id: COG1148

COG function: function code C; Heterodisulfide reductase, subunit A and related polyferredoxins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR003953
- InterPro:   IPR012285 [H]

Pfam domain/function: PF00890 FAD_binding_2; PF00037 Fer4 [H]

EC number: =1.8.98.1 [H]

Molecular weight: Translated: 70559; Mature: 70559

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
4.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIGVFVCHCGSNIGGTVDCAKVAEIARTYPDVVYADDPMYTCAEPGQAAIEAAIHEHKL
CEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEECCCCEECCCCCHHHHHHHHHHHCC
DGVVVASCSPRMHEPTFRRTVERAGLNRYMLEMANIREHVSWIGRDKEANTNKSAELVLL
CCEEEEECCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHEEEE
AVEKLRNNKPLLAKSFDVNKRVLVIGGGVAGIQAALDCADGGVPVVLVERDATIGGKMAK
EHHHHCCCCCCEEEECCCCCEEEEEECCHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHH
LDKTFPTVDCSACILGPKMVDVAQHSNITLYAYSEVEDISGYVGNFTVKIRKRATYVDWS
HCCCCCCCCCCCEEECCHHHHHHCCCCEEEEEECCHHHHCCCCCEEEEEEEECCEEECHH
LCTGCGACTEKCPSKKTPDAFNEEISNTTAITIAFPQAIPKKAVINAGHCRQFIKGKCGV
HHCCCCHHHHHCCCCCCCCHHHHHHCCCEEEEEEECCCCCHHHHCCCHHHHHHHCCCCCC
CAKICPTGAIKYDMEDEIITEEVGSIVAATGYDLMDWTVYQEYGGGAYPDVITSLQYERL
EEECCCCCCEEECCCHHHHHHHHCCEEEECCCCHHEEEEEHHCCCCCCHHHHHHHHHHHH
LNASGPTAGHIKRPSDGKEPKNIVFVQCVGSRDKSIGRPYCSGFCCMYTAKQAILTKDHI
HCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHCCCHHHHHHHHHHHHHCCC
PDSQSYVFYMDIRAAGKMYDEFTRRTMEEYGTEYIRGRVSQIYPDGQGQLVVMGVDTLMG
CCCCCEEEEEEECHHHHHHHHHHHHHHHHHCHHHHHCHHHHCCCCCCCEEEEEEHHHHHC
QAIEIKADLVVLAVGIEASKGAPQLAEKLRISYDSYGFFMESHVKLKPVETNTAGVYLAG
CEEEEEEEEEEEEEECCCCCCCHHHHHHHHCCCCCCCEEEECCEEEEEECCCCCCEEEEE
VCQGTKDIPASVAQGSAAAAKVLALFAKDKLESDPQIAQVDMRRCVNCGKCIQCCPFGAI
ECCCCCCCCHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHCCCCCC
KEVEVRGEGKAQVIETVCQGCGLCTATCPQGAIQLSHATDNQILAEVNALCQL
EEEEECCCCHHHHHHHHHHHCCCEECCCCCCCEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MRIGVFVCHCGSNIGGTVDCAKVAEIARTYPDVVYADDPMYTCAEPGQAAIEAAIHEHKL
CEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEECCCCEECCCCCHHHHHHHHHHHCC
DGVVVASCSPRMHEPTFRRTVERAGLNRYMLEMANIREHVSWIGRDKEANTNKSAELVLL
CCEEEEECCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHEEEE
AVEKLRNNKPLLAKSFDVNKRVLVIGGGVAGIQAALDCADGGVPVVLVERDATIGGKMAK
EHHHHCCCCCCEEEECCCCCEEEEEECCHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHH
LDKTFPTVDCSACILGPKMVDVAQHSNITLYAYSEVEDISGYVGNFTVKIRKRATYVDWS
HCCCCCCCCCCCEEECCHHHHHHCCCCEEEEEECCHHHHCCCCCEEEEEEEECCEEECHH
LCTGCGACTEKCPSKKTPDAFNEEISNTTAITIAFPQAIPKKAVINAGHCRQFIKGKCGV
HHCCCCHHHHHCCCCCCCCHHHHHHCCCEEEEEEECCCCCHHHHCCCHHHHHHHCCCCCC
CAKICPTGAIKYDMEDEIITEEVGSIVAATGYDLMDWTVYQEYGGGAYPDVITSLQYERL
EEECCCCCCEEECCCHHHHHHHHCCEEEECCCCHHEEEEEHHCCCCCCHHHHHHHHHHHH
LNASGPTAGHIKRPSDGKEPKNIVFVQCVGSRDKSIGRPYCSGFCCMYTAKQAILTKDHI
HCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHCCCHHHHHHHHHHHHHCCC
PDSQSYVFYMDIRAAGKMYDEFTRRTMEEYGTEYIRGRVSQIYPDGQGQLVVMGVDTLMG
CCCCCEEEEEEECHHHHHHHHHHHHHHHHHCHHHHHCHHHHCCCCCCCEEEEEEHHHHHC
QAIEIKADLVVLAVGIEASKGAPQLAEKLRISYDSYGFFMESHVKLKPVETNTAGVYLAG
CEEEEEEEEEEEEEECCCCCCCHHHHHHHHCCCCCCCEEEECCEEEEEECCCCCCEEEEE
VCQGTKDIPASVAQGSAAAAKVLALFAKDKLESDPQIAQVDMRRCVNCGKCIQCCPFGAI
ECCCCCCCCHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHCCCCCC
KEVEVRGEGKAQVIETVCQGCGLCTATCPQGAIQLSHATDNQILAEVNALCQL
EEEEECCCCHHHHHHHHHHHCCCEECCCCCCCEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9063468; 11930014 [H]