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The map label for this gene is hdrB [H]

Identifier: 220905361

GI number: 220905361

Start: 2528263

End: 2529183

Strand: Direct

Name: hdrB [H]

Synonym: Ddes_2099

Alternate gene names: 220905361

Gene position: 2528263-2529183 (Clockwise)

Preceding gene: 220905360

Following gene: 220905362

Centisome position: 87.99

GC content: 61.89

Gene sequence:

>921_bases
ATGAATTTTGCCTACTACCCCGGCTGCTCGGCCCGAGGCTCTTCCAAGGACTACGAAATGTCCACCCAGGCCGTGTGCAA
GGCGCTGGACATGAACCTTGTGGATATTCCGGACTGGAACTGCTGTGGCTCCACCCCGGCCCACGCCGTGGATACCGAGC
TTTCCGCGGCCCTGTGCGTGCGCAACCTCGACATTGCCGCCCAGCAGCAGGCCGAACTGCTGCTCACGCCCTGCCCGAGC
TGCCTTTCCAATCTCAAGCTGGCCGCCAGACGTATGGAAGACCCCGCGTTTCGCCAACGTGTGGACGAACTGCTCGACGG
CCCCTCGGCCAAGACCTTTCCGCCCGTGACCTCGGTCATGCAGGGCATTGCCGAAGCCTATGATATGGAAACCATCGCCG
CCCGGGTGCGCAAAAGCCTCAAGGGTCTCAGGCTGGCCGCCTATTACGGCTGCCTCATGAGCCGCCCCGCAGAGATCATG
AACTTCGGCGATCCGGAAAATCCCACACTTATGGAAAGCATGCTCGCTGCCTGCGGCGCTGAAATGGTGGACTTTCCCCT
CAAAACAGCCTGCTGTGGCGCGTCGTTCGGCATTCCCGAACGCGTGATGACGGCCCGCAATTCCGGGCGCATCCTCGACC
TTGCCACGCAGCTTGGCGTGGATGCCGTCATCGTGGCCTGCCCGCTCTGCCAGATGAACCTTGATCTGCGCCAGCAGCAG
GCATCCAAAGAAATGGGCACGGCCTTCCACCTGCCGGTGCTCTACTTCACCCAGATGATGGGCATAGCCTTTGGCCTTGA
CCACAAGGAACTGGGGCTTAACAAACTGCGCGTCAGCCCTGACGGCCTCATCCGCAAGCTGGACGAACTCCGGCGCAATT
CCGCCGCCGCAGACAAGGCCGCTGAAGGAGGCAGGTCATGA

Upstream 100 bases:

>100_bases
AGCTGGGCCTCAAACCCCACGTTCTGCCCCAGGGAGCAGCCCCGGTTTCGCGCATTTTCCAGCGCTATAAAGAACGCGCC
AAGCGCGAGGGGGTACGCCC

Downstream 100 bases:

>100_bases
GAATAGGCGTTTTCGTCTGCCATTGCGGCAGCAATATCGGCGGCACCGTTGACTGCGCCAAGGTGGCTGAGATTGCCCGC
ACCTACCCTGACGTGGTGTA

Product: CoB--CoM heterodisulfide reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MNFAYYPGCSARGSSKDYEMSTQAVCKALDMNLVDIPDWNCCGSTPAHAVDTELSAALCVRNLDIAAQQQAELLLTPCPS
CLSNLKLAARRMEDPAFRQRVDELLDGPSAKTFPPVTSVMQGIAEAYDMETIAARVRKSLKGLRLAAYYGCLMSRPAEIM
NFGDPENPTLMESMLAACGAEMVDFPLKTACCGASFGIPERVMTARNSGRILDLATQLGVDAVIVACPLCQMNLDLRQQQ
ASKEMGTAFHLPVLYFTQMMGIAFGLDHKELGLNKLRVSPDGLIRKLDELRRNSAAADKAAEGGRS

Sequences:

>Translated_306_residues
MNFAYYPGCSARGSSKDYEMSTQAVCKALDMNLVDIPDWNCCGSTPAHAVDTELSAALCVRNLDIAAQQQAELLLTPCPS
CLSNLKLAARRMEDPAFRQRVDELLDGPSAKTFPPVTSVMQGIAEAYDMETIAARVRKSLKGLRLAAYYGCLMSRPAEIM
NFGDPENPTLMESMLAACGAEMVDFPLKTACCGASFGIPERVMTARNSGRILDLATQLGVDAVIVACPLCQMNLDLRQQQ
ASKEMGTAFHLPVLYFTQMMGIAFGLDHKELGLNKLRVSPDGLIRKLDELRRNSAAADKAAEGGRS
>Mature_306_residues
MNFAYYPGCSARGSSKDYEMSTQAVCKALDMNLVDIPDWNCCGSTPAHAVDTELSAALCVRNLDIAAQQQAELLLTPCPS
CLSNLKLAARRMEDPAFRQRVDELLDGPSAKTFPPVTSVMQGIAEAYDMETIAARVRKSLKGLRLAAYYGCLMSRPAEIM
NFGDPENPTLMESMLAACGAEMVDFPLKTACCGASFGIPERVMTARNSGRILDLATQLGVDAVIVACPLCQMNLDLRQQQ
ASKEMGTAFHLPVLYFTQMMGIAFGLDHKELGLNKLRVSPDGLIRKLDELRRNSAAADKAAEGGRS

Specific function: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrB may have a function in energy transduction [H]

COG id: COG2048

COG function: function code C; Heterodisulfide reductase, subunit B

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hdrB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017678
- InterPro:   IPR004017 [H]

Pfam domain/function: PF02754 CCG [H]

EC number: =1.8.98.1 [H]

Molecular weight: Translated: 33186; Mature: 33186

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.2 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
9.5 %Cys+Met (Translated Protein)
4.2 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
9.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFAYYPGCSARGSSKDYEMSTQAVCKALDMNLVDIPDWNCCGSTPAHAVDTELSAALCV
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEECCCCCCCCCCCCHHHHHHHHHHHHH
RNLDIAAQQQAELLLTPCPSCLSNLKLAARRMEDPAFRQRVDELLDGPSAKTFPPVTSVM
HHCCHHHHHHHHEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHH
QGIAEAYDMETIAARVRKSLKGLRLAAYYGCLMSRPAEIMNFGDPENPTLMESMLAACGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHCH
EMVDFPLKTACCGASFGIPERVMTARNSGRILDLATQLGVDAVIVACPLCQMNLDLRQQQ
HHHHCCHHHHHCCCCCCCHHHHHHHCCCCCEEHHHHHHCHHHHHHHHHHHHCCHHHHHHH
ASKEMGTAFHLPVLYFTQMMGIAFGLDHKELGLNKLRVSPDGLIRKLDELRRNSAAADKA
HHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHCCHHEECCHHHHHHHHHHHHHHHHHHHHH
AEGGRS
HCCCCC
>Mature Secondary Structure
MNFAYYPGCSARGSSKDYEMSTQAVCKALDMNLVDIPDWNCCGSTPAHAVDTELSAALCV
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEECCCCCCCCCCCCHHHHHHHHHHHHH
RNLDIAAQQQAELLLTPCPSCLSNLKLAARRMEDPAFRQRVDELLDGPSAKTFPPVTSVM
HHCCHHHHHHHHEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHH
QGIAEAYDMETIAARVRKSLKGLRLAAYYGCLMSRPAEIMNFGDPENPTLMESMLAACGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHCH
EMVDFPLKTACCGASFGIPERVMTARNSGRILDLATQLGVDAVIVACPLCQMNLDLRQQQ
HHHHCCHHHHHCCCCCCCHHHHHHHCCCCCEEHHHHHHCHHHHHHHHHHHHCCHHHHHHH
ASKEMGTAFHLPVLYFTQMMGIAFGLDHKELGLNKLRVSPDGLIRKLDELRRNSAAADKA
HHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHCCHHEECCHHHHHHHHHHHHHHHHHHHHH
AEGGRS
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]