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The map label for this gene is argD [H]

Identifier: 220905220

GI number: 220905220

Start: 2361462

End: 2362667

Strand: Direct

Name: argD [H]

Synonym: Ddes_1958

Alternate gene names: 220905220

Gene position: 2361462-2362667 (Clockwise)

Preceding gene: 220905219

Following gene: 220905221

Centisome position: 82.18

GC content: 62.11

Gene sequence:

>1206_bases
ATGTCACAAGCCTTTGCTGCCGTCAAAGCCGGGGAAGAAAGCCTGCTCTGCCGTTCTTACAGCCGCTATCCCGTGGCCGT
GGTCCGAGGCAAGGGCGCGCGATTGTGGGATGTGGACGGCAAGGAATATGTCGACCTGCTGGCGGGCATTGCCGTTACGA
CCCTCGGACACTGCAACGACGAAGTAAACGCCGCTCTGGCCGCACAGGCCGAAAAACTCTGGCATGTGAGCAATCTCTTC
TATCAGGAAGAGCAGCTTGAGCTGGCGCGCCTGCTTTTGTCCACCAGCCATCACAATAAGGCTTTTTTCTGCAACTCCGG
GGCCGAGGCCAACGAGGCATGCATCAAGCTGGCGCGCCGCTACATGCGCAAGATCAGGCAGCGCGATGCCTGTGAAATCA
TCACCCTGAACGGCTGTTTCCACGGGCGCACACTGGGCGCGCTTGCCGCTACAGGACGTGAAAACCTCAGCGACGGCTTC
ACCCCCCTGCCTGAAGGATTCAGGCAGGTTCCGGCCAATGATCTGGACGCCATGAGCGCGGCCATCACTCCGGCCACTGC
CGCGGTTCTGGTGGAAGTGGTACAGGGTGAAGGCGGCATTGTCCCCCTGTCCGGCGACTATCTGCGGCAGCTTGAGGCCC
TGTGCCGCCAGCGCGGCGTGCTCTTCATGTGCGATGAAGTCCAGGCGGGACTTGGCCGCACCGGCACATTCTGGGCCTTT
CAGAATCACGGGCTGACGCCTGACGCCATCAGCGTCGCCAAGGCCCTTGCCAATGGCCTGCCCATGGGAGCCATGCTGGC
TACAGACGAGGTCGCCGCAGGTTTTGAGGCGGGAAGCCATGCCACCACGTTCGGCGGCGGCGCTCTGGTCTCCGGCGTGG
CGACCAGGGTAGTTGAAATCCTGCTGCGCGACAGGCTGACCGAACGCGCCGCCCAGCTGGGCGCGCACATGAAGCACACC
CTCGCAGACATGCAGGAACGCCTGCCCGGAAAAATTGTCGAAGTGCGGGGCATGGGCCTTATGCTGGGCATCGAGCTTGC
CGTGGACGGCAAGGCCGTGTGGGACGAATTGCTGCACCGGGGCTATATCTGCAACCTGAGCCACGGCACGACCCTTCGCC
TTCTGCCGCCCCTGAATATTGACCAGGCTGACCTGGATGGCTTTCTGACGACGCTTGAAGACATCCTGCGGAATTTTACC
GCCTGA

Upstream 100 bases:

>100_bases
CGTGGTTCCGGCGGCTTCGGGCACACAGGGCGCTGACAGCGCCGCGCCCCTGCGGCGCGTCCAAACCAACCATCTGTTTA
TCGAGAAAAGGAGTCCGTCC

Downstream 100 bases:

>100_bases
AAAGCACCGCAGGGGCTTTACAGACAGATCATTGTAGACTAAATAGTCTGCGTTGAAAATCAGGTACGACTATTACGGCA
ACCCCGCTTCGGCGGGGTTG

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MSQAFAAVKAGEESLLCRSYSRYPVAVVRGKGARLWDVDGKEYVDLLAGIAVTTLGHCNDEVNAALAAQAEKLWHVSNLF
YQEEQLELARLLLSTSHHNKAFFCNSGAEANEACIKLARRYMRKIRQRDACEIITLNGCFHGRTLGALAATGRENLSDGF
TPLPEGFRQVPANDLDAMSAAITPATAAVLVEVVQGEGGIVPLSGDYLRQLEALCRQRGVLFMCDEVQAGLGRTGTFWAF
QNHGLTPDAISVAKALANGLPMGAMLATDEVAAGFEAGSHATTFGGGALVSGVATRVVEILLRDRLTERAAQLGAHMKHT
LADMQERLPGKIVEVRGMGLMLGIELAVDGKAVWDELLHRGYICNLSHGTTLRLLPPLNIDQADLDGFLTTLEDILRNFT
A

Sequences:

>Translated_401_residues
MSQAFAAVKAGEESLLCRSYSRYPVAVVRGKGARLWDVDGKEYVDLLAGIAVTTLGHCNDEVNAALAAQAEKLWHVSNLF
YQEEQLELARLLLSTSHHNKAFFCNSGAEANEACIKLARRYMRKIRQRDACEIITLNGCFHGRTLGALAATGRENLSDGF
TPLPEGFRQVPANDLDAMSAAITPATAAVLVEVVQGEGGIVPLSGDYLRQLEALCRQRGVLFMCDEVQAGLGRTGTFWAF
QNHGLTPDAISVAKALANGLPMGAMLATDEVAAGFEAGSHATTFGGGALVSGVATRVVEILLRDRLTERAAQLGAHMKHT
LADMQERLPGKIVEVRGMGLMLGIELAVDGKAVWDELLHRGYICNLSHGTTLRLLPPLNIDQADLDGFLTTLEDILRNFT
A
>Mature_400_residues
SQAFAAVKAGEESLLCRSYSRYPVAVVRGKGARLWDVDGKEYVDLLAGIAVTTLGHCNDEVNAALAAQAEKLWHVSNLFY
QEEQLELARLLLSTSHHNKAFFCNSGAEANEACIKLARRYMRKIRQRDACEIITLNGCFHGRTLGALAATGRENLSDGFT
PLPEGFRQVPANDLDAMSAAITPATAAVLVEVVQGEGGIVPLSGDYLRQLEALCRQRGVLFMCDEVQAGLGRTGTFWAFQ
NHGLTPDAISVAKALANGLPMGAMLATDEVAAGFEAGSHATTFGGGALVSGVATRVVEILLRDRLTERAAQLGAHMKHTL
ADMQERLPGKIVEVRGMGLMLGIELAVDGKAVWDELLHRGYICNLSHGTTLRLLPPLNIDQADLDGFLTTLEDILRNFTA

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=392, Percent_Identity=34.1836734693878, Blast_Score=223, Evalue=3e-58,
Organism=Homo sapiens, GI13994255, Length=429, Percent_Identity=28.6713286713287, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI284507298, Length=306, Percent_Identity=34.3137254901961, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI24119277, Length=433, Percent_Identity=28.4064665127021, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI37574042, Length=423, Percent_Identity=26.7139479905437, Blast_Score=138, Evalue=8e-33,
Organism=Homo sapiens, GI226442705, Length=423, Percent_Identity=26.0047281323877, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI226442709, Length=392, Percent_Identity=26.7857142857143, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI188536080, Length=431, Percent_Identity=24.5939675174014, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI38679950, Length=431, Percent_Identity=24.5939675174014, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI38679946, Length=431, Percent_Identity=24.5939675174014, Blast_Score=93, Evalue=4e-19,
Organism=Escherichia coli, GI1788044, Length=385, Percent_Identity=40, Blast_Score=286, Evalue=1e-78,
Organism=Escherichia coli, GI1789759, Length=389, Percent_Identity=38.3033419023136, Blast_Score=268, Evalue=6e-73,
Organism=Escherichia coli, GI145693181, Length=369, Percent_Identity=34.4173441734417, Blast_Score=197, Evalue=7e-52,
Organism=Escherichia coli, GI1789016, Length=395, Percent_Identity=31.3924050632911, Blast_Score=178, Evalue=5e-46,
Organism=Escherichia coli, GI1787560, Length=400, Percent_Identity=31, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI1786991, Length=392, Percent_Identity=27.2959183673469, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786349, Length=253, Percent_Identity=30.8300395256917, Blast_Score=94, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI25144271, Length=398, Percent_Identity=33.4170854271357, Blast_Score=217, Evalue=8e-57,
Organism=Caenorhabditis elegans, GI32564660, Length=426, Percent_Identity=30.7511737089202, Blast_Score=211, Evalue=5e-55,
Organism=Caenorhabditis elegans, GI25144274, Length=283, Percent_Identity=33.2155477031802, Blast_Score=148, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI71992977, Length=430, Percent_Identity=27.2093023255814, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI71981843, Length=167, Percent_Identity=31.7365269461078, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17541228, Length=217, Percent_Identity=28.110599078341, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6324432, Length=405, Percent_Identity=32.5925925925926, Blast_Score=223, Evalue=6e-59,
Organism=Saccharomyces cerevisiae, GI6323470, Length=403, Percent_Identity=34.2431761786601, Blast_Score=221, Evalue=2e-58,
Organism=Saccharomyces cerevisiae, GI6324386, Length=448, Percent_Identity=25.2232142857143, Blast_Score=107, Evalue=4e-24,
Organism=Drosophila melanogaster, GI21357415, Length=385, Percent_Identity=33.7662337662338, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI161085790, Length=434, Percent_Identity=29.0322580645161, Blast_Score=195, Evalue=4e-50,
Organism=Drosophila melanogaster, GI28574759, Length=421, Percent_Identity=29.4536817102138, Blast_Score=193, Evalue=2e-49,
Organism=Drosophila melanogaster, GI21356575, Length=422, Percent_Identity=29.1469194312796, Blast_Score=157, Evalue=9e-39,
Organism=Drosophila melanogaster, GI281366494, Length=374, Percent_Identity=25.1336898395722, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24667139, Length=374, Percent_Identity=25.1336898395722, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24667143, Length=374, Percent_Identity=25.1336898395722, Blast_Score=96, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43186; Mature: 43055

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQAFAAVKAGEESLLCRSYSRYPVAVVRGKGARLWDVDGKEYVDLLAGIAVTTLGHCND
CCCHHHHHHCCCHHHHHHHCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHCCCH
EVNAALAAQAEKLWHVSNLFYQEEQLELARLLLSTSHHNKAFFCNSGAEANEACIKLARR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHH
YMRKIRQRDACEIITLNGCFHGRTLGALAATGRENLSDGFTPLPEGFRQVPANDLDAMSA
HHHHHHCCCCCEEEEECCCCCCCHHHHHHHCCCCHHCCCCCCCCHHHHHCCCCHHHHHHH
AITPATAAVLVEVVQGEGGIVPLSGDYLRQLEALCRQRGVLFMCDEVQAGLGRTGTFWAF
HCCHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHCCEEEEECHHHHCCCCCCEEEEE
QNHGLTPDAISVAKALANGLPMGAMLATDEVAAGFEAGSHATTFGGGALVSGVATRVVEI
CCCCCCHHHHHHHHHHHCCCCCCCEEEHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
LLRDRLTERAAQLGAHMKHTLADMQERLPGKIVEVRGMGLMLGIELAVDGKAVWDELLHR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEEEEEEECCHHHHHHHHHC
GYICNLSHGTTLRLLPPLNIDQADLDGFLTTLEDILRNFTA
CEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SQAFAAVKAGEESLLCRSYSRYPVAVVRGKGARLWDVDGKEYVDLLAGIAVTTLGHCND
CCHHHHHHCCCHHHHHHHCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHCCCH
EVNAALAAQAEKLWHVSNLFYQEEQLELARLLLSTSHHNKAFFCNSGAEANEACIKLARR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHH
YMRKIRQRDACEIITLNGCFHGRTLGALAATGRENLSDGFTPLPEGFRQVPANDLDAMSA
HHHHHHCCCCCEEEEECCCCCCCHHHHHHHCCCCHHCCCCCCCCHHHHHCCCCHHHHHHH
AITPATAAVLVEVVQGEGGIVPLSGDYLRQLEALCRQRGVLFMCDEVQAGLGRTGTFWAF
HCCHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHCCEEEEECHHHHCCCCCCEEEEE
QNHGLTPDAISVAKALANGLPMGAMLATDEVAAGFEAGSHATTFGGGALVSGVATRVVEI
CCCCCCHHHHHHHHHHHCCCCCCCEEEHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
LLRDRLTERAAQLGAHMKHTLADMQERLPGKIVEVRGMGLMLGIELAVDGKAVWDELLHR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEEEEEEECCHHHHHHHHHC
GYICNLSHGTTLRLLPPLNIDQADLDGFLTTLEDILRNFTA
CEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]