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The map label for this gene is mnmG [H]

Identifier: 220905196

GI number: 220905196

Start: 2328474

End: 2330456

Strand: Direct

Name: mnmG [H]

Synonym: Ddes_1934

Alternate gene names: 220905196

Gene position: 2328474-2330456 (Clockwise)

Preceding gene: 220905195

Following gene: 220905197

Centisome position: 81.03

GC content: 62.88

Gene sequence:

>1983_bases
ATGTCTGATTCATACAACGCAAGCACATTTGACTGCATCGTGGCCGGAGGCGGCCATGCCGGCTGCGAAGCCGCCGTGGC
CCTTGCCCGCATGGGACACAGCGTGCTGCTCATCAGCGGCAACCTTGACCGCCTGGGCTACCTTTCCTGCAATCCCGCCA
TCGGCGGCCTTGCCAAGGGGCACATGGCGCGCGAAATCGACGCCCTGGGCGGCATGATGGGCCTGTGGGCCGATGCCGCG
GGCATACAGTTTCGCATGCTGAACATGAGCAAAGGACCGGCCGTGCGGGCTACCCGCGCGCAGATGGACCGCCTTGTCTA
TCAGCGAGTGGTGCAGCAGACGCTCTATTCCACGCCCGGGCTGCGCATCTGGCAGGATTCTGTCATCGAGATCACCGCGG
GCGACAGCCGCGCCACAGGTGTGCGCACGGCACAGGGGCTTGAGTTTTCCGCCCGCCATGTGCTGCTGACCACGGGAACA
TTCCTTGACGGCCGCATCCATATGGGGCTGACCAGCATCCCCGGCGGCCGCCTTGGCGATGCGCCCGCACTGGGTCTTTC
CGACAGTCTGCGCACTCTGGGCTTTGAACTGGGCCGCCTCAAAACAGGCACTACCCCGCGGCTGTTGAAATCATCCATCA
ATTATGCCGTGCTGGAAGAGCAAAAAGGTGATGATCCGGCACCGGCATTCAGTTTTCACGGCCCAGGCCCGGTCTTGCCT
CAGGTTCCCTGCCATGTGACCTGGACCAATGAGCAGGCCCACGAGATCATCCGCAGCGGCTTTGACCGCTCGCCCATGTT
CACGGGCGTTATCAAGGGAACGGGCGCGCGTTACTGCCCCTCCATTGAAGACAAGATCGCCCGCTTTCCCGACAGGGAAC
GGCATCAGATATTCCTTGAACCTGAAGGCCTGGACAGCGCCGAAGTTTATGCCAACGGCATCTCCACCAGCCTGCCGCTG
GATGTGCAGATCGGCATGATCCACGCTGTTCCCGGCCTGGAAAACGCCGTCATGCTGCGCCCGGGCTACGCCATCGAATA
CGATTTTTCCGATCCCGTGCAGCTTATGCCCACCCTTGAAAGCAAGGCCGTTCCCGGCCTGTGGCTGGCGGGGCAGATCA
ACGGCACTTCCGGCTACGAAGAGGCTGCGGCCCAGGGCCTGTGGGCGGCGCTGAACATTTCGTGCAGGCTGCGTGAAATG
CCGCCCTTTCTGCTGGGACGCGACGAGGCCTACATGGCTGTTCTGGTGGACGATCTGGTAACTTCTGGCACTCAGGAGCC
TTACCGCATGTTTACCTCGCGCGCCGAACACCGCCTGCTGCTGCGCGAAGACAATGCCGATACACGCCTGACGCCCCACG
GGCGGCAGCTGGGCCTGGTAAACGATGCCCATTGGGATGCATTCTGCCGCAAGCAGGATGCCGCAAACCGCCTGCGTTCG
GGCCTCGAGCAAAAACGCATCCCTGCCCCAGGGCGCGGCTCTCTCGCGGATGGACCTGCAACGGACTCTGGGCAAGATAA
AGGCACCGTAACAACGGGCATGTCCGCGACAGGCAAGACCGCCGACCTGCCCGTTGGGCGCACCCTGGCCGAGGCCCTGC
GCAGGCCCGAACTGGACCTGCACGGCCTTGCGGCACTTCTGCGCTCCTGTGCCTGTGAAGACACGGCCGCCGCCGCGGAA
TTTCTTGAGCATGAGATGGCGCTGGCCGGAGCTGGCGTGTGTGAAAGCGTGCAGACAGAGATCAAGTATGCGGGATATCT
GAGCCGTCAACGCGAACTGGTTGCGCGCGCGGCAAAGCTTGAGTCCACAGCCTTGCCCCCGGATTTGGATTATGCCACAG
TAGCAGGGTTGTCCCGTGAGGTGACGGAAAAGCTCGACCGTGTCAGACCCCTGAGCCTTGGCCAGGCCGGGCGCATTTCA
GGGGTCACCCCGGCGGCAGTGGGCTGCCTGGAAATACACTTGCACAAACTGGGCCTGCTCTGA

Upstream 100 bases:

>100_bases
TGTGTTGAAAACACCTGCCATCAGCCCAACGAGCGCTCCTCCATCACCGCAGCCATTAAAGATGCCCAGGTGTTCACCCA
CATACTCATGAATTCCGCCC

Downstream 100 bases:

>100_bases
TGTCGGCAAGGCGGCACAGCAGGCACACGGCAGGCCCCGGGCCAAAAATTATTCTTCCTCCGGCCGGACCGGAAGGGCCG
CAAGGCTCCTCACGGCACAG

Product: tRNA uridine 5-carboxymethylaminomethyl modification protein GidA

Products: NA

Alternate protein names: Glucose-inhibited division protein A [H]

Number of amino acids: Translated: 660; Mature: 659

Protein sequence:

>660_residues
MSDSYNASTFDCIVAGGGHAGCEAAVALARMGHSVLLISGNLDRLGYLSCNPAIGGLAKGHMAREIDALGGMMGLWADAA
GIQFRMLNMSKGPAVRATRAQMDRLVYQRVVQQTLYSTPGLRIWQDSVIEITAGDSRATGVRTAQGLEFSARHVLLTTGT
FLDGRIHMGLTSIPGGRLGDAPALGLSDSLRTLGFELGRLKTGTTPRLLKSSINYAVLEEQKGDDPAPAFSFHGPGPVLP
QVPCHVTWTNEQAHEIIRSGFDRSPMFTGVIKGTGARYCPSIEDKIARFPDRERHQIFLEPEGLDSAEVYANGISTSLPL
DVQIGMIHAVPGLENAVMLRPGYAIEYDFSDPVQLMPTLESKAVPGLWLAGQINGTSGYEEAAAQGLWAALNISCRLREM
PPFLLGRDEAYMAVLVDDLVTSGTQEPYRMFTSRAEHRLLLREDNADTRLTPHGRQLGLVNDAHWDAFCRKQDAANRLRS
GLEQKRIPAPGRGSLADGPATDSGQDKGTVTTGMSATGKTADLPVGRTLAEALRRPELDLHGLAALLRSCACEDTAAAAE
FLEHEMALAGAGVCESVQTEIKYAGYLSRQRELVARAAKLESTALPPDLDYATVAGLSREVTEKLDRVRPLSLGQAGRIS
GVTPAAVGCLEIHLHKLGLL

Sequences:

>Translated_660_residues
MSDSYNASTFDCIVAGGGHAGCEAAVALARMGHSVLLISGNLDRLGYLSCNPAIGGLAKGHMAREIDALGGMMGLWADAA
GIQFRMLNMSKGPAVRATRAQMDRLVYQRVVQQTLYSTPGLRIWQDSVIEITAGDSRATGVRTAQGLEFSARHVLLTTGT
FLDGRIHMGLTSIPGGRLGDAPALGLSDSLRTLGFELGRLKTGTTPRLLKSSINYAVLEEQKGDDPAPAFSFHGPGPVLP
QVPCHVTWTNEQAHEIIRSGFDRSPMFTGVIKGTGARYCPSIEDKIARFPDRERHQIFLEPEGLDSAEVYANGISTSLPL
DVQIGMIHAVPGLENAVMLRPGYAIEYDFSDPVQLMPTLESKAVPGLWLAGQINGTSGYEEAAAQGLWAALNISCRLREM
PPFLLGRDEAYMAVLVDDLVTSGTQEPYRMFTSRAEHRLLLREDNADTRLTPHGRQLGLVNDAHWDAFCRKQDAANRLRS
GLEQKRIPAPGRGSLADGPATDSGQDKGTVTTGMSATGKTADLPVGRTLAEALRRPELDLHGLAALLRSCACEDTAAAAE
FLEHEMALAGAGVCESVQTEIKYAGYLSRQRELVARAAKLESTALPPDLDYATVAGLSREVTEKLDRVRPLSLGQAGRIS
GVTPAAVGCLEIHLHKLGLL
>Mature_659_residues
SDSYNASTFDCIVAGGGHAGCEAAVALARMGHSVLLISGNLDRLGYLSCNPAIGGLAKGHMAREIDALGGMMGLWADAAG
IQFRMLNMSKGPAVRATRAQMDRLVYQRVVQQTLYSTPGLRIWQDSVIEITAGDSRATGVRTAQGLEFSARHVLLTTGTF
LDGRIHMGLTSIPGGRLGDAPALGLSDSLRTLGFELGRLKTGTTPRLLKSSINYAVLEEQKGDDPAPAFSFHGPGPVLPQ
VPCHVTWTNEQAHEIIRSGFDRSPMFTGVIKGTGARYCPSIEDKIARFPDRERHQIFLEPEGLDSAEVYANGISTSLPLD
VQIGMIHAVPGLENAVMLRPGYAIEYDFSDPVQLMPTLESKAVPGLWLAGQINGTSGYEEAAAQGLWAALNISCRLREMP
PFLLGRDEAYMAVLVDDLVTSGTQEPYRMFTSRAEHRLLLREDNADTRLTPHGRQLGLVNDAHWDAFCRKQDAANRLRSG
LEQKRIPAPGRGSLADGPATDSGQDKGTVTTGMSATGKTADLPVGRTLAEALRRPELDLHGLAALLRSCACEDTAAAAEF
LEHEMALAGAGVCESVQTEIKYAGYLSRQRELVARAAKLESTALPPDLDYATVAGLSREVTEKLDRVRPLSLGQAGRISG
VTPAAVGCLEIHLHKLGLL

Specific function: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 [H]

COG id: COG0445

COG function: function code D; NAD/FAD-utilizing enzyme apparently involved in cell division

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MnmG family [H]

Homologues:

Organism=Homo sapiens, GI74024895, Length=659, Percent_Identity=41.7298937784522, Blast_Score=457, Evalue=1e-128,
Organism=Homo sapiens, GI19882217, Length=684, Percent_Identity=40.2046783625731, Blast_Score=442, Evalue=1e-124,
Organism=Homo sapiens, GI183227703, Length=699, Percent_Identity=39.3419170243205, Blast_Score=438, Evalue=1e-123,
Organism=Escherichia coli, GI2367273, Length=654, Percent_Identity=51.3761467889908, Blast_Score=639, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17534255, Length=647, Percent_Identity=38.1761978361669, Blast_Score=437, Evalue=1e-123,
Organism=Saccharomyces cerevisiae, GI6321202, Length=649, Percent_Identity=41.6024653312789, Blast_Score=469, Evalue=1e-133,
Organism=Drosophila melanogaster, GI24658174, Length=661, Percent_Identity=41.4523449319213, Blast_Score=460, Evalue=1e-129,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004416
- InterPro:   IPR002218
- InterPro:   IPR020595 [H]

Pfam domain/function: PF01134 GIDA [H]

EC number: NA

Molecular weight: Translated: 70795; Mature: 70663

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS01280 GIDA_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSYNASTFDCIVAGGGHAGCEAAVALARMGHSVLLISGNLDRLGYLSCNPAIGGLAKG
CCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCEEEEECCCCCCCHHHH
HMAREIDALGGMMGLWADAAGIQFRMLNMSKGPAVRATRAQMDRLVYQRVVQQTLYSTPG
HHHHHHHHHCCHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
LRIWQDSVIEITAGDSRATGVRTAQGLEFSARHVLLTTGTFLDGRIHMGLTSIPGGRLGD
CEEECCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCEECCEEEECEECCCCCCCCC
APALGLSDSLRTLGFELGRLKTGTTPRLLKSSINYAVLEEQKGDDPAPAFSFHGPGPVLP
CCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCC
QVPCHVTWTNEQAHEIIRSGFDRSPMFTGVIKGTGARYCPSIEDKIARFPDRERHQIFLE
CCCEEEEECCHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCHHHHHHHCCCCCCCEEEEC
PEGLDSAEVYANGISTSLPLDVQIGMIHAVPGLENAVMLRPGYAIEYDFSDPVQLMPTLE
CCCCCHHHHHHCCCCCCCCEEEEEEEEEECCCCCCEEEECCCEEEEECCCCCHHHHCCHH
SKAVPGLWLAGQINGTSGYEEAAAQGLWAALNISCRLREMPPFLLGRDEAYMAVLVDDLV
HCCCCCEEEEEEECCCCCHHHHHHCCCEEEEEEEEEEECCCCHHCCCCCHHHHHHHHHHH
TSGTQEPYRMFTSRAEHRLLLREDNADTRLTPHGRQLGLVNDAHWDAFCRKQDAANRLRS
HCCCCHHHHHHHHHHHCEEEEEECCCCCEECCCCCEECCCCCCHHHHHHHHHHHHHHHHH
GLEQKRIPAPGRGSLADGPATDSGQDKGTVTTGMSATGKTADLPVGRTLAEALRRPELDL
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHCCCCCH
HGLAALLRSCACEDTAAAAEFLEHEMALAGAGVCESVQTEIKYAGYLSRQRELVARAAKL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESTALPPDLDYATVAGLSREVTEKLDRVRPLSLGQAGRISGVTPAAVGCLEIHLHKLGLL
HHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SDSYNASTFDCIVAGGGHAGCEAAVALARMGHSVLLISGNLDRLGYLSCNPAIGGLAKG
CCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCEEEEECCCCCCCHHHH
HMAREIDALGGMMGLWADAAGIQFRMLNMSKGPAVRATRAQMDRLVYQRVVQQTLYSTPG
HHHHHHHHHCCHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
LRIWQDSVIEITAGDSRATGVRTAQGLEFSARHVLLTTGTFLDGRIHMGLTSIPGGRLGD
CEEECCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCEECCEEEECEECCCCCCCCC
APALGLSDSLRTLGFELGRLKTGTTPRLLKSSINYAVLEEQKGDDPAPAFSFHGPGPVLP
CCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCC
QVPCHVTWTNEQAHEIIRSGFDRSPMFTGVIKGTGARYCPSIEDKIARFPDRERHQIFLE
CCCEEEEECCHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCHHHHHHHCCCCCCCEEEEC
PEGLDSAEVYANGISTSLPLDVQIGMIHAVPGLENAVMLRPGYAIEYDFSDPVQLMPTLE
CCCCCHHHHHHCCCCCCCCEEEEEEEEEECCCCCCEEEECCCEEEEECCCCCHHHHCCHH
SKAVPGLWLAGQINGTSGYEEAAAQGLWAALNISCRLREMPPFLLGRDEAYMAVLVDDLV
HCCCCCEEEEEEECCCCCHHHHHHCCCEEEEEEEEEEECCCCHHCCCCCHHHHHHHHHHH
TSGTQEPYRMFTSRAEHRLLLREDNADTRLTPHGRQLGLVNDAHWDAFCRKQDAANRLRS
HCCCCHHHHHHHHHHHCEEEEEECCCCCEECCCCCEECCCCCCHHHHHHHHHHHHHHHHH
GLEQKRIPAPGRGSLADGPATDSGQDKGTVTTGMSATGKTADLPVGRTLAEALRRPELDL
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHCCCCCH
HGLAALLRSCACEDTAAAAEFLEHEMALAGAGVCESVQTEIKYAGYLSRQRELVARAAKL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESTALPPDLDYATVAGLSREVTEKLDRVRPLSLGQAGRISGVTPAAVGCLEIHLHKLGLL
HHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA