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The map label for this gene is cobO [H]

Identifier: 220905105

GI number: 220905105

Start: 2222986

End: 2223489

Strand: Direct

Name: cobO [H]

Synonym: Ddes_1842

Alternate gene names: 220905105

Gene position: 2222986-2223489 (Clockwise)

Preceding gene: 220905104

Following gene: 220905106

Centisome position: 77.36

GC content: 62.3

Gene sequence:

>504_bases
ATGATTCTTGTTTATACGGGTGACGGCAAAGGCAAGACAAGCGCCTGCACTGGGCAGGCCGTACGCGCCATGGGCCAGGG
CATGACCGTGGCTTTTGGTCAGTTTATGAAACGCGATGGACAGGCAGGTGAGCAGGCCATGCTGGCTCAATGGCTGGGGC
CACGCTTTCTGGCCGGGGGCTGCGGCTTTTTGCGCCGTGACGAAGACCGCCCCGCCCACCGTGAGGCCGCATTGCAAGTG
CTTGCATGGGCGCGACGACAGATGGCCGAAGCCGATATGCTGGTGCTGGATGAAAGCCTTTACGCCTTTGGCGCGGGCAT
TCTTTTGCGCGAGGAGATTGAAGAACTCATGGCTCTGGCGCGGCAGCAGGCTACGCACCTGGTGCTTTCGGGCCGGAACG
CGCCGGACTGGCTGGTGGACGCGGCGGACCTTGTGACCTCCATGACCGAAATCAAGCATCCCTGGCGCGCCGGCATCAAG
GCCGCGCCCGGCATCGAATATTGA

Upstream 100 bases:

>100_bases
TTATAGAGCGCCGGGGCTACAACATACGGTCACTCATGCAGGCAGACGCGCCCGGCGCGTGTCCTTCCTGTCACGCGGCC
CTGACAGGAGTGTGGAGCTG

Downstream 100 bases:

>100_bases
GGGCCGCGCCGCATGAAAGCCTTTACCCTTTCATGCGAGACAGCACGCCCCTTGCAGCAACACGTTCCCACACTCTGTGA
AAAAACCGTAAAGGACTGTT

Product: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 167; Mature: 167

Protein sequence:

>167_residues
MILVYTGDGKGKTSACTGQAVRAMGQGMTVAFGQFMKRDGQAGEQAMLAQWLGPRFLAGGCGFLRRDEDRPAHREAALQV
LAWARRQMAEADMLVLDESLYAFGAGILLREEIEELMALARQQATHLVLSGRNAPDWLVDAADLVTSMTEIKHPWRAGIK
AAPGIEY

Sequences:

>Translated_167_residues
MILVYTGDGKGKTSACTGQAVRAMGQGMTVAFGQFMKRDGQAGEQAMLAQWLGPRFLAGGCGFLRRDEDRPAHREAALQV
LAWARRQMAEADMLVLDESLYAFGAGILLREEIEELMALARQQATHLVLSGRNAPDWLVDAADLVTSMTEIKHPWRAGIK
AAPGIEY
>Mature_167_residues
MILVYTGDGKGKTSACTGQAVRAMGQGMTVAFGQFMKRDGQAGEQAMLAQWLGPRFLAGGCGFLRRDEDRPAHREAALQV
LAWARRQMAEADMLVLDESLYAFGAGILLREEIEELMALARQQATHLVLSGRNAPDWLVDAADLVTSMTEIKHPWRAGIK
AAPGIEY

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=169, Percent_Identity=34.3195266272189, Blast_Score=91, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 18235; Mature: 18235

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVYTGDGKGKTSACTGQAVRAMGQGMTVAFGQFMKRDGQAGEQAMLAQWLGPRFLAGG
CEEEEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHCC
CGFLRRDEDRPAHREAALQVLAWARRQMAEADMLVLDESLYAFGAGILLREEIEELMALA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQQATHLVLSGRNAPDWLVDAADLVTSMTEIKHPWRAGIKAAPGIEY
HHHHHHHEEECCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCC
>Mature Secondary Structure
MILVYTGDGKGKTSACTGQAVRAMGQGMTVAFGQFMKRDGQAGEQAMLAQWLGPRFLAGG
CEEEEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHCC
CGFLRRDEDRPAHREAALQVLAWARRQMAEADMLVLDESLYAFGAGILLREEIEELMALA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQQATHLVLSGRNAPDWLVDAADLVTSMTEIKHPWRAGIKAAPGIEY
HHHHHHHEEECCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1917862 [H]