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The map label for this gene is cfa [H]

Identifier: 220905094

GI number: 220905094

Start: 2207888

End: 2209000

Strand: Reverse

Name: cfa [H]

Synonym: Ddes_1831

Alternate gene names: 220905094

Gene position: 2209000-2207888 (Counterclockwise)

Preceding gene: 220905095

Following gene: 220905093

Centisome position: 76.88

GC content: 54.09

Gene sequence:

>1113_bases
ATGTTTGAATCGGACATCAAAAAAATGCTGGCTTCAGTAGATGTGGAGATTGGTGGATCCCGCCCGTGGGATATTCAGGT
TCATAACACTAAACTTTACAGCCGTGTCCTGTGTTTCGCCAACCTGGGTCTGGGTGAGGCGTATATGGAAGGCTGGTGGA
ACTGCACGGCCCTTGACCAGTTTTTTTACCGTGTGCTGCGGGGTGGTCTGGAAAAGCGTTTCCGTTTTACCCTGCCTGTT
CTGCTGGAGGTTCTTGCCTATTCATTCCGCAATCTGCAAAGCCCTGAGCGGGCGCGTATGGTGGCGGTGCACCACTATGA
TTTCGGCAATGACGTTTTTGAGGCCATGCTTGATCCGGCCATGCAGTACAGCTGCGGTTACTGGGAAAATGCCACGAATC
TGGAGGAAGCACAGCGGCAGAAGATGGATATGATCTGCCGCAAGCTACAGTTGCAGCCGGGTATGAACGTGCTGGACATC
GGTTGCGGCTGGGGCGGGCTTGGACGCTACATGGCGCGGGAATACGGCGTACGGGTCACTGGAGTGACGGTTTCCGAGGC
ACAGGCACGTTATGCACGAGAACACGGCGAAGGCGAGGACCTCCGCTGGTTGTTGCAGGACTACCGTACGCTTTCCGGCA
CGTTTGACCGTATTGTTTCTGTGGGCATGTTCGAGCATGTGGGGCGCAAGAACTATGCTGTTTATATGGACACCGTTCGC
CGTCTTCTGGCAGAAGACGGCCTTTTTTTACTGCACACCATAGGAGGGAACAAGGCGCGCCGTTGCGTGGACCCCTGGAT
TGAAAAATACATCTTCAAAAACGGCATCCTGCCCAGCATCCATCTGGTCGGCAACTGTGTTGAAGGCCGTATGGTGATGG
AAGACTGGGAAAATTTCGGCGCGTATTATGATAAGACCCTCATGTGTTGGGCCGAAAATTTCGCCCGGGGCAGAAAAGAG
GGGAGATTCCAGTGCAGCGAGGCACAGAGCCGCATGTTTCTGTACTATCTGTTAAGCTGCGCCGGGGCTTTCCGCGCCCG
TGACCTTCAGTTATGGCAGATCGTCCTTTCGCCAAGAGGTGTTGAAGGGGGATATAGACGGCCGAAGATATAA

Upstream 100 bases:

>100_bases
GTTATATGGAGGAGTCTGACTTACGTAACTAGCAAAATTATTTGCTTTCTGTAAGGGCTTACGCATGTTTTTGCGTCAAG
ATCGATCAGGAGTATCAGTT

Downstream 100 bases:

>100_bases
TATAGCCATGCCCGCCCTTGCCTTGCAGCAGGTAGGGCGTTATGGCTTCTGCTGCACGCCGTGACGCATGTTGTACGGCG
CCCGTTTTATCCTTCAGAGA

Product: cyclopropane fatty acyl phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MFESDIKKMLASVDVEIGGSRPWDIQVHNTKLYSRVLCFANLGLGEAYMEGWWNCTALDQFFYRVLRGGLEKRFRFTLPV
LLEVLAYSFRNLQSPERARMVAVHHYDFGNDVFEAMLDPAMQYSCGYWENATNLEEAQRQKMDMICRKLQLQPGMNVLDI
GCGWGGLGRYMAREYGVRVTGVTVSEAQARYAREHGEGEDLRWLLQDYRTLSGTFDRIVSVGMFEHVGRKNYAVYMDTVR
RLLAEDGLFLLHTIGGNKARRCVDPWIEKYIFKNGILPSIHLVGNCVEGRMVMEDWENFGAYYDKTLMCWAENFARGRKE
GRFQCSEAQSRMFLYYLLSCAGAFRARDLQLWQIVLSPRGVEGGYRRPKI

Sequences:

>Translated_370_residues
MFESDIKKMLASVDVEIGGSRPWDIQVHNTKLYSRVLCFANLGLGEAYMEGWWNCTALDQFFYRVLRGGLEKRFRFTLPV
LLEVLAYSFRNLQSPERARMVAVHHYDFGNDVFEAMLDPAMQYSCGYWENATNLEEAQRQKMDMICRKLQLQPGMNVLDI
GCGWGGLGRYMAREYGVRVTGVTVSEAQARYAREHGEGEDLRWLLQDYRTLSGTFDRIVSVGMFEHVGRKNYAVYMDTVR
RLLAEDGLFLLHTIGGNKARRCVDPWIEKYIFKNGILPSIHLVGNCVEGRMVMEDWENFGAYYDKTLMCWAENFARGRKE
GRFQCSEAQSRMFLYYLLSCAGAFRARDLQLWQIVLSPRGVEGGYRRPKI
>Mature_370_residues
MFESDIKKMLASVDVEIGGSRPWDIQVHNTKLYSRVLCFANLGLGEAYMEGWWNCTALDQFFYRVLRGGLEKRFRFTLPV
LLEVLAYSFRNLQSPERARMVAVHHYDFGNDVFEAMLDPAMQYSCGYWENATNLEEAQRQKMDMICRKLQLQPGMNVLDI
GCGWGGLGRYMAREYGVRVTGVTVSEAQARYAREHGEGEDLRWLLQDYRTLSGTFDRIVSVGMFEHVGRKNYAVYMDTVR
RLLAEDGLFLLHTIGGNKARRCVDPWIEKYIFKNGILPSIHLVGNCVEGRMVMEDWENFGAYYDKTLMCWAENFARGRKE
GRFQCSEAQSRMFLYYLLSCAGAFRARDLQLWQIVLSPRGVEGGYRRPKI

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=360, Percent_Identity=56.1111111111111, Blast_Score=402, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI133904226, Length=391, Percent_Identity=25.5754475703325, Blast_Score=127, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 42819; Mature: 42819

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFESDIKKMLASVDVEIGGSRPWDIQVHNTKLYSRVLCFANLGLGEAYMEGWWNCTALDQ
CCHHHHHHHHHHCCCEECCCCCEEEEEECHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHH
FFYRVLRGGLEKRFRFTLPVLLEVLAYSFRNLQSPERARMVAVHHYDFGNDVFEAMLDPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEEEEECCCCHHHHHHHHHHH
MQYSCGYWENATNLEEAQRQKMDMICRKLQLQPGMNVLDIGCGWGGLGRYMAREYGVRVT
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHCCEEE
GVTVSEAQARYAREHGEGEDLRWLLQDYRTLSGTFDRIVSVGMFEHVGRKNYAVYMDTVR
EEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHH
RLLAEDGLFLLHTIGGNKARRCVDPWIEKYIFKNGILPSIHLVGNCVEGRMVMEDWENFG
HHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHH
AYYDKTLMCWAENFARGRKEGRFQCSEAQSRMFLYYLLSCAGAFRARDLQLWQIVLSPRG
HHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHEECCCC
VEGGYRRPKI
CCCCCCCCCC
>Mature Secondary Structure
MFESDIKKMLASVDVEIGGSRPWDIQVHNTKLYSRVLCFANLGLGEAYMEGWWNCTALDQ
CCHHHHHHHHHHCCCEECCCCCEEEEEECHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHH
FFYRVLRGGLEKRFRFTLPVLLEVLAYSFRNLQSPERARMVAVHHYDFGNDVFEAMLDPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEEEEECCCCHHHHHHHHHHH
MQYSCGYWENATNLEEAQRQKMDMICRKLQLQPGMNVLDIGCGWGGLGRYMAREYGVRVT
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHCCEEE
GVTVSEAQARYAREHGEGEDLRWLLQDYRTLSGTFDRIVSVGMFEHVGRKNYAVYMDTVR
EEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHH
RLLAEDGLFLLHTIGGNKARRCVDPWIEKYIFKNGILPSIHLVGNCVEGRMVMEDWENFG
HHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHH
AYYDKTLMCWAENFARGRKEGRFQCSEAQSRMFLYYLLSCAGAFRARDLQLWQIVLSPRG
HHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHEECCCC
VEGGYRRPKI
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]