Click here to switch to the map view.

The map label for this gene is rnhB [H]

Identifier: 220905054

GI number: 220905054

Start: 2165044

End: 2165736

Strand: Direct

Name: rnhB [H]

Synonym: Ddes_1791

Alternate gene names: 220905054

Gene position: 2165044-2165736 (Clockwise)

Preceding gene: 220905053

Following gene: 220905055

Centisome position: 75.35

GC content: 63.49

Gene sequence:

>693_bases
GTGAAAAAACATCCCTCCCACCAGCAAGGCCTGCTTGAACTGCCGGGCACGCCTGCTATTCCGGCCGCCGGGCAAACAGC
CGGTATTGATGAGGCCGGACGCGGCTGTCTGGCCGGGCCGGTGGTAGCCGGAGCCGTAATCCTGCCGCCGGAGTACGATC
TGCCGGGCCTTGCCGACTCAAAGGCCTGCACAGCCCGGCAACGCGGCCTGCTCGCCCCGCGCATCAAAAAATCTGCGCTG
GCCTGGGGCCTGGGAATCGTCTGGCCCGACCGCATCGACCGCATCAACATTCTTCAGGCCACCTTTGAAGCCATGAGCAT
GGCAGTGCGCCACCTGCGCATCACGCCGCAAATCCTGCTTGTGGACGGTAACAAGGTCATCCCCGAACCGGCACTCGCGC
CGCAGTGGCTACGGGCACATGGCGATACCCTGCCGTTGCAGCGGGCCATTGTGGGCGGCGATGCCGCAGAGCCCGCCATT
TCCGCAGCATCCATTCTGGCAAAAACCTGCCGTGATACCCTCATGACAAGCCTGGACAAACGCTGGCCCGGCTATGGTTT
TGCCATCCACAAAGGCTACGGCACAAAGGAGCATTACGAGGCTCTGCGCCGCCTTGGCCCCTGCCCGCAGCACAGGCTGA
CCTTCCGGGGCGTCTGCAAAGACTGTACGGTGGAACAGGGCTGCCTGTTATGA

Upstream 100 bases:

>100_bases
TGTTGTGCCACCCGCGCAAATATTCCACAGCTGCCGGCCTTCCCGCGAGCACTTCACACTCCGGCAAGTGCCGCAAAGCC
GCACCAAACAGGAACATGGC

Downstream 100 bases:

>100_bases
ATCTGCGCAAGTTGCTGCCCGCCTTTTTTGCCGGAAAGTCAGGTAAAATTTCTCCGGAAGGCAAAATGCCCTCCGGTTCC
GGAAACACGGCGAAAGACGC

Product: Ribonuclease H

Products: NA

Alternate protein names: RNase HII [H]

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MKKHPSHQQGLLELPGTPAIPAAGQTAGIDEAGRGCLAGPVVAGAVILPPEYDLPGLADSKACTARQRGLLAPRIKKSAL
AWGLGIVWPDRIDRINILQATFEAMSMAVRHLRITPQILLVDGNKVIPEPALAPQWLRAHGDTLPLQRAIVGGDAAEPAI
SAASILAKTCRDTLMTSLDKRWPGYGFAIHKGYGTKEHYEALRRLGPCPQHRLTFRGVCKDCTVEQGCLL

Sequences:

>Translated_230_residues
MKKHPSHQQGLLELPGTPAIPAAGQTAGIDEAGRGCLAGPVVAGAVILPPEYDLPGLADSKACTARQRGLLAPRIKKSAL
AWGLGIVWPDRIDRINILQATFEAMSMAVRHLRITPQILLVDGNKVIPEPALAPQWLRAHGDTLPLQRAIVGGDAAEPAI
SAASILAKTCRDTLMTSLDKRWPGYGFAIHKGYGTKEHYEALRRLGPCPQHRLTFRGVCKDCTVEQGCLL
>Mature_230_residues
MKKHPSHQQGLLELPGTPAIPAAGQTAGIDEAGRGCLAGPVVAGAVILPPEYDLPGLADSKACTARQRGLLAPRIKKSAL
AWGLGIVWPDRIDRINILQATFEAMSMAVRHLRITPQILLVDGNKVIPEPALAPQWLRAHGDTLPLQRAIVGGDAAEPAI
SAASILAKTCRDTLMTSLDKRWPGYGFAIHKGYGTKEHYEALRRLGPCPQHRLTFRGVCKDCTVEQGCLL

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids [H]

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family [H]

Homologues:

Organism=Escherichia coli, GI1786380, Length=197, Percent_Identity=45.1776649746193, Blast_Score=150, Evalue=9e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01351 RNase_HII [H]

EC number: =3.1.26.4 [H]

Molecular weight: Translated: 24696; Mature: 24696

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKHPSHQQGLLELPGTPAIPAAGQTAGIDEAGRGCLAGPVVAGAVILPPEYDLPGLADS
CCCCCCCCCCCEECCCCCCCCCCCCCCCCCHHCCCCCCCHHHHCEEEECCCCCCCCCCCC
KACTARQRGLLAPRIKKSALAWGLGIVWPDRIDRINILQATFEAMSMAVRHLRITPQILL
HHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEE
VDGNKVIPEPALAPQWLRAHGDTLPLQRAIVGGDAAEPAISAASILAKTCRDTLMTSLDK
EECCEECCCCCCCHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RWPGYGFAIHKGYGTKEHYEALRRLGPCPQHRLTFRGVCKDCTVEQGCLL
CCCCCCEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKKHPSHQQGLLELPGTPAIPAAGQTAGIDEAGRGCLAGPVVAGAVILPPEYDLPGLADS
CCCCCCCCCCCEECCCCCCCCCCCCCCCCCHHCCCCCCCHHHHCEEEECCCCCCCCCCCC
KACTARQRGLLAPRIKKSALAWGLGIVWPDRIDRINILQATFEAMSMAVRHLRITPQILL
HHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEE
VDGNKVIPEPALAPQWLRAHGDTLPLQRAIVGGDAAEPAISAASILAKTCRDTLMTSLDK
EECCEECCCCCCCHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RWPGYGFAIHKGYGTKEHYEALRRLGPCPQHRLTFRGVCKDCTVEQGCLL
CCCCCCEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA