Click here to switch to the map view.

The map label for this gene is moeB [H]

Identifier: 220905036

GI number: 220905036

Start: 2142773

End: 2143828

Strand: Reverse

Name: moeB [H]

Synonym: Ddes_1773

Alternate gene names: 220905036

Gene position: 2143828-2142773 (Counterclockwise)

Preceding gene: 220905037

Following gene: 220905026

Centisome position: 74.61

GC content: 62.12

Gene sequence:

>1056_bases
ATGACAGCATCCCGGTTGCGGGCTTTTTTCAGGCCCTACCTGCGTACCGTCTATCCCGGTCATTCTGTCTTTACGGCGTC
CGGCGGGCGCGACACCCATGAAGAAATCTGGTTTACAGCCATTGCGGGCATACGGGCCTGGGCGGCCGGACAAGGCCTGT
CCACGCGCGAGGCTGTGGCGCGTCTTGTGCCAGCCGGCATCTGGCCCGAGAGTTTTCGCCGCAATTACGGACTGTTTGCC
GTGCATGATGTGACGCACCTGTTACGTTGCCGGGTACTTGTGCTCGGTTGCGGCGGCCTGGGCGGGCATGTGGCAGAACT
GCTGGCCCGCACGGGTATCGGTTTTCTGCGCCTTGTGGACAATGATGTCTTTGACGAGAGCAATCTCAACCGTCAGCGTT
TCTGCGCCCAGAGTACGCTGGGCCGTCCCAAGGCGCAGGTTGTGCGCGATGCTCTGACGGACATCGCCTTTCATCTGGAG
GCCGAGGCATTGCAACTGGCCGCCGATAAAAGCAGCATGCCGGAACTTGTGCGCGGGATGGATGCGGTTGTGGACTGCCT
GGACAGTATCGGGGCCAAGCTGGCGCTGGAAAAAGCCTCACTGGCTGCGGGCAGCCCTTTTGTCCACGGTTCCATCCTGC
GTGAAGAAGGCTTTGCCTATGTGAATTCCGGGCCGGATGCGTGCCTGAACACGCTTTATCCAGGGGGACAGGGAACGGAA
GAACTGGCGGTGTCCCGGCATGAAGCCATGGGAACCCTTGCCCCGGCAGCCGTGGCCTGCCTGATGGTAAAATTGTGCCT
GCGTGCCTTGCTGGCTCCCGCGTCCGTTCATGCTCGCGCCGGGGCCAGTGATACCCTGACTGTCGGCGCAAATACCGTTG
CCGCGGCCGTTCCGGACATTGTCACAGCGGCTGGCGGACATGCTGCCGCAGGAGCCGCTGACACCGGCAGCGAAGCGGCA
GACAAGCATCAGGGCGGGCAGGCGCATGGCCTCCGTTCCCCCCTCTATCATCTGGACCTCTCCATTCCCGAACTGGAGCG
CTTTTTTTGGGGGTGA

Upstream 100 bases:

>100_bases
ATGATCAACGGACGCCAGCGCAAGGCGGACGATCTCCTGCGCGACGGCGATCGCGTTGCCTTCTTCCCGGCTGTCGGTGG
AGGCTAGGCGTCCGTTGGCC

Downstream 100 bases:

>100_bases
CGGCGCTCAGCCGCGCTGCGCGATGCCGGCAGCGGGATCGGCCGGGGTCTGGACAATAAACTGCAGAATACGGTGTCAGC
CCATTGTGCTGTATCTGTTC

Product: UBA/THIF-type NAD/FAD binding protein

Products: NA

Alternate protein names: MoaD protein adenylase; Molybdopterin-converting factor subunit 1 adenylase [H]

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MTASRLRAFFRPYLRTVYPGHSVFTASGGRDTHEEIWFTAIAGIRAWAAGQGLSTREAVARLVPAGIWPESFRRNYGLFA
VHDVTHLLRCRVLVLGCGGLGGHVAELLARTGIGFLRLVDNDVFDESNLNRQRFCAQSTLGRPKAQVVRDALTDIAFHLE
AEALQLAADKSSMPELVRGMDAVVDCLDSIGAKLALEKASLAAGSPFVHGSILREEGFAYVNSGPDACLNTLYPGGQGTE
ELAVSRHEAMGTLAPAAVACLMVKLCLRALLAPASVHARAGASDTLTVGANTVAAAVPDIVTAAGGHAAAGAADTGSEAA
DKHQGGQAHGLRSPLYHLDLSIPELERFFWG

Sequences:

>Translated_351_residues
MTASRLRAFFRPYLRTVYPGHSVFTASGGRDTHEEIWFTAIAGIRAWAAGQGLSTREAVARLVPAGIWPESFRRNYGLFA
VHDVTHLLRCRVLVLGCGGLGGHVAELLARTGIGFLRLVDNDVFDESNLNRQRFCAQSTLGRPKAQVVRDALTDIAFHLE
AEALQLAADKSSMPELVRGMDAVVDCLDSIGAKLALEKASLAAGSPFVHGSILREEGFAYVNSGPDACLNTLYPGGQGTE
ELAVSRHEAMGTLAPAAVACLMVKLCLRALLAPASVHARAGASDTLTVGANTVAAAVPDIVTAAGGHAAAGAADTGSEAA
DKHQGGQAHGLRSPLYHLDLSIPELERFFWG
>Mature_350_residues
TASRLRAFFRPYLRTVYPGHSVFTASGGRDTHEEIWFTAIAGIRAWAAGQGLSTREAVARLVPAGIWPESFRRNYGLFAV
HDVTHLLRCRVLVLGCGGLGGHVAELLARTGIGFLRLVDNDVFDESNLNRQRFCAQSTLGRPKAQVVRDALTDIAFHLEA
EALQLAADKSSMPELVRGMDAVVDCLDSIGAKLALEKASLAAGSPFVHGSILREEGFAYVNSGPDACLNTLYPGGQGTEE
LAVSRHEAMGTLAPAAVACLMVKLCLRALLAPASVHARAGASDTLTVGANTVAAAVPDIVTAAGGHAAAGAADTGSEAAD
KHQGGQAHGLRSPLYHLDLSIPELERFFWG

Specific function: Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein moaD [H]

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=189, Percent_Identity=33.8624338624339, Blast_Score=79, Evalue=7e-15,
Organism=Escherichia coli, GI1787048, Length=148, Percent_Identity=36.4864864864865, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI87082356, Length=164, Percent_Identity=31.7073170731707, Blast_Score=78, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17540406, Length=158, Percent_Identity=30.379746835443, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6321903, Length=217, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24582879, Length=184, Percent_Identity=31.5217391304348, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR012730
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 37046; Mature: 36914

Theoretical pI: Translated: 6.83; Mature: 6.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASRLRAFFRPYLRTVYPGHSVFTASGGRDTHEEIWFTAIAGIRAWAAGQGLSTREAVA
CCHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
RLVPAGIWPESFRRNYGLFAVHDVTHLLRCRVLVLGCGGLGGHVAELLARTGIGFLRLVD
HHHCCCCCHHHHHCCCCCEEHHHHHHHHHHHHHHEECCCCHHHHHHHHHHCCCHHEEECC
NDVFDESNLNRQRFCAQSTLGRPKAQVVRDALTDIAFHLEAEALQLAADKSSMPELVRGM
CHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
DAVVDCLDSIGAKLALEKASLAAGSPFVHGSILREEGFAYVNSGPDACLNTLYPGGQGTE
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEECCCHHHHHHHCCCCCCCHH
ELAVSRHEAMGTLAPAAVACLMVKLCLRALLAPASVHARAGASDTLTVGANTVAAAVPDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEECCHHHHHHHHHH
VTAAGGHAAAGAADTGSEAADKHQGGQAHGLRSPLYHLDLSIPELERFFWG
HHHCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCHHEECCCCHHHHHHHCC
>Mature Secondary Structure 
TASRLRAFFRPYLRTVYPGHSVFTASGGRDTHEEIWFTAIAGIRAWAAGQGLSTREAVA
CHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
RLVPAGIWPESFRRNYGLFAVHDVTHLLRCRVLVLGCGGLGGHVAELLARTGIGFLRLVD
HHHCCCCCHHHHHCCCCCEEHHHHHHHHHHHHHHEECCCCHHHHHHHHHHCCCHHEEECC
NDVFDESNLNRQRFCAQSTLGRPKAQVVRDALTDIAFHLEAEALQLAADKSSMPELVRGM
CHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
DAVVDCLDSIGAKLALEKASLAAGSPFVHGSILREEGFAYVNSGPDACLNTLYPGGQGTE
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEECCCHHHHHHHCCCCCCCHH
ELAVSRHEAMGTLAPAAVACLMVKLCLRALLAPASVHARAGASDTLTVGANTVAAAVPDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEECCHHHHHHHHHH
VTAAGGHAAAGAADTGSEAADKHQGGQAHGLRSPLYHLDLSIPELERFFWG
HHHCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCHHEECCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3045084; 8905232; 9278503 [H]