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The map label for this gene is dadA [H]

Identifier: 220904950

GI number: 220904950

Start: 2030005

End: 2031210

Strand: Direct

Name: dadA [H]

Synonym: Ddes_1686

Alternate gene names: 220904950

Gene position: 2030005-2031210 (Clockwise)

Preceding gene: 220904949

Following gene: 220904951

Centisome position: 70.65

GC content: 59.45

Gene sequence:

>1206_bases
ATGAGCAGCAAACATGCGGCCGGTGCCGTTGTCATTGGCGGGGGTGCCGTCGGTACGGCTGTGGCCTGCTATCTTGCCAT
GGACGGGGTGGATGTCGCCCTTGTTGAACGCGGCGAATTCGCCTGGGGTTCCAGCCGCCGTTGCGATGGTCATGTGGTCA
CCTATGACACGCCGCCAGGCGCATACAGCCGGTTCTGCAAGTGCGGGCAGGACATGTTTCATGATGCCGCAGATTTTCTA
CCCGTAGATTTTGAATTTTGCCCCGAAGGGCTTGGCCTGCTGGTTGATGATGAGCGCGACCTTGAAGCCGTGCGCGCCAA
CTACGAAGGCAAGAAAAAAGAAGGCATAGACGTGACCCTGTGGGACAGAAACGAGCTTCGCCACCACGAGCCAAATATCG
GCGACAGCATCCTGGCCTGCCTGAATTTCAATGGCGACTGCAAGCTTAACCCCATGCGTCTTTGCCAGGGCCTTGCCATG
CATGCCAGGGCCAACGGAGCGGTACTCATGACCGGAACCCGGGTCACCGGGCTGCAGATGGAAAAAGGCCGCATTACCGC
CGTGGAAACGGACAAAGGGCGTATATACGCGGCCAATGTCGTCCTTGCGGCGGGCGTCTGGACGCCCGGCCTTGCCCATA
TGGCTGGTCTCGCCGTTCCCGTCCGCCCCCGGCAGGGTCATGTGCTGGTCACCGAACGGGTTCGTAATCTGGTGGGCAAA
AACTACGCTGAATACGGCTATCTGCTGGCAAAAGGCGGAAAAACCAGGGACACCATCACCCCTGAAATGGAGCAGTTCGG
CGTGGCTTTTGTACTTGAGCCTTCCCATGCCGGAACTGTCCTGCTGGGCAGCAGCCGCCGCTATGTGGGGATGGACATCC
GCCCCAACCCCGCAGTCATGCGCGCCATTGCCCAGCGCGCCCGTCATTTTTATCCCTCTCTGGCCCAAACGCGCCTCATC
CGCTGCTATGCGGGCCTTCGGCCCTGCACTCCGGATGCCAAACCCATTATATCGCCCACCCATATCAAAGGCCTTTTTGT
GGCGACAGGCCATGAGGGCAACGGCATAGGGCTTTCCCTTATCACCGGCAGGCTCATTGCGGAAATGGTGCGCGGACAGT
CCCCGTTTATGGACATAAGCAACATGAGTCTTGACAGGTTCGGGCTTAACCCTGCGGCCCATACTCCAGAAACGGCTTCC
GCCTGA

Upstream 100 bases:

>100_bases
TGCTCAAACAGGCGGACTTTAGCTGACCCATATACCGGGAGGCGGCCACAGGCCGCCTCCCGTACATGTTTTCATGCAAC
GAGGAACAGGAGAAACTGCC

Downstream 100 bases:

>100_bases
GGAGAACGAGCATGTTTGTCAAAGTGACCCCTCCTGCGGACAGGCAGGTGACCATCTATTTTGAAGGGCAGGCCCTTGAG
GTCGAAAAGGGCATCAGTGT

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MSSKHAAGAVVIGGGAVGTAVACYLAMDGVDVALVERGEFAWGSSRRCDGHVVTYDTPPGAYSRFCKCGQDMFHDAADFL
PVDFEFCPEGLGLLVDDERDLEAVRANYEGKKKEGIDVTLWDRNELRHHEPNIGDSILACLNFNGDCKLNPMRLCQGLAM
HARANGAVLMTGTRVTGLQMEKGRITAVETDKGRIYAANVVLAAGVWTPGLAHMAGLAVPVRPRQGHVLVTERVRNLVGK
NYAEYGYLLAKGGKTRDTITPEMEQFGVAFVLEPSHAGTVLLGSSRRYVGMDIRPNPAVMRAIAQRARHFYPSLAQTRLI
RCYAGLRPCTPDAKPIISPTHIKGLFVATGHEGNGIGLSLITGRLIAEMVRGQSPFMDISNMSLDRFGLNPAAHTPETAS
A

Sequences:

>Translated_401_residues
MSSKHAAGAVVIGGGAVGTAVACYLAMDGVDVALVERGEFAWGSSRRCDGHVVTYDTPPGAYSRFCKCGQDMFHDAADFL
PVDFEFCPEGLGLLVDDERDLEAVRANYEGKKKEGIDVTLWDRNELRHHEPNIGDSILACLNFNGDCKLNPMRLCQGLAM
HARANGAVLMTGTRVTGLQMEKGRITAVETDKGRIYAANVVLAAGVWTPGLAHMAGLAVPVRPRQGHVLVTERVRNLVGK
NYAEYGYLLAKGGKTRDTITPEMEQFGVAFVLEPSHAGTVLLGSSRRYVGMDIRPNPAVMRAIAQRARHFYPSLAQTRLI
RCYAGLRPCTPDAKPIISPTHIKGLFVATGHEGNGIGLSLITGRLIAEMVRGQSPFMDISNMSLDRFGLNPAAHTPETAS
A
>Mature_400_residues
SSKHAAGAVVIGGGAVGTAVACYLAMDGVDVALVERGEFAWGSSRRCDGHVVTYDTPPGAYSRFCKCGQDMFHDAADFLP
VDFEFCPEGLGLLVDDERDLEAVRANYEGKKKEGIDVTLWDRNELRHHEPNIGDSILACLNFNGDCKLNPMRLCQGLAMH
ARANGAVLMTGTRVTGLQMEKGRITAVETDKGRIYAANVVLAAGVWTPGLAHMAGLAVPVRPRQGHVLVTERVRNLVGKN
YAEYGYLLAKGGKTRDTITPEMEQFGVAFVLEPSHAGTVLLGSSRRYVGMDIRPNPAVMRAIAQRARHFYPSLAQTRLIR
CYAGLRPCTPDAKPIISPTHIKGLFVATGHEGNGIGLSLITGRLIAEMVRGQSPFMDISNMSLDRFGLNPAAHTPETASA

Specific function: Oxidative deamination of D-amino acids [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Inner Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DadA oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI194306651, Length=425, Percent_Identity=22.8235294117647, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787438, Length=376, Percent_Identity=21.5425531914894, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788574, Length=364, Percent_Identity=23.0769230769231, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023080
- InterPro:   IPR006076 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.4.99.1 [H]

Molecular weight: Translated: 43261; Mature: 43130

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSKHAAGAVVIGGGAVGTAVACYLAMDGVDVALVERGEFAWGSSRRCDGHVVTYDTPPG
CCCCCCCCEEEECCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCC
AYSRFCKCGQDMFHDAADFLPVDFEFCPEGLGLLVDDERDLEAVRANYEGKKKEGIDVTL
HHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCEEEECCHHHHHHHCCCCCCCCCCCEEEE
WDRNELRHHEPNIGDSILACLNFNGDCKLNPMRLCQGLAMHARANGAVLMTGTRVTGLQM
ECCCCCCCCCCCCCCCEEEEECCCCCCEECHHHHHHHHHHHCCCCCEEEEECCEEEEEEE
EKGRITAVETDKGRIYAANVVLAAGVWTPGLAHMAGLAVPVRPRQGHVLVTERVRNLVGK
CCCEEEEEECCCCEEEEEEEEEEECCCCCCHHHHHCCEEECCCCCCCEEHHHHHHHHHCC
NYAEYGYLLAKGGKTRDTITPEMEQFGVAFVLEPSHAGTVLLGSSRRYVGMDIRPNPAVM
CHHHHCEEEECCCCCCCCCCCCHHHCCEEEEECCCCCCEEEEECCCCEEEEECCCCHHHH
RAIAQRARHFYPSLAQTRLIRCYAGLRPCTPDAKPIISPTHIKGLFVATGHEGNGIGLSL
HHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEHHH
ITGRLIAEMVRGQSPFMDISNMSLDRFGLNPAAHTPETASA
HHHHHHHHHHCCCCCCEECCCCCHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SSKHAAGAVVIGGGAVGTAVACYLAMDGVDVALVERGEFAWGSSRRCDGHVVTYDTPPG
CCCCCCCEEEECCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCC
AYSRFCKCGQDMFHDAADFLPVDFEFCPEGLGLLVDDERDLEAVRANYEGKKKEGIDVTL
HHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCEEEECCHHHHHHHCCCCCCCCCCCEEEE
WDRNELRHHEPNIGDSILACLNFNGDCKLNPMRLCQGLAMHARANGAVLMTGTRVTGLQM
ECCCCCCCCCCCCCCCEEEEECCCCCCEECHHHHHHHHHHHCCCCCEEEEECCEEEEEEE
EKGRITAVETDKGRIYAANVVLAAGVWTPGLAHMAGLAVPVRPRQGHVLVTERVRNLVGK
CCCEEEEEECCCCEEEEEEEEEEECCCCCCHHHHHCCEEECCCCCCCEEHHHHHHHHHCC
NYAEYGYLLAKGGKTRDTITPEMEQFGVAFVLEPSHAGTVLLGSSRRYVGMDIRPNPAVM
CHHHHCEEEECCCCCCCCCCCCHHHCCEEEEECCCCCCEEEEECCCCEEEEECCCCHHHH
RAIAQRARHFYPSLAQTRLIRCYAGLRPCTPDAKPIISPTHIKGLFVATGHEGNGIGLSL
HHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEHHH
ITGRLIAEMVRGQSPFMDISNMSLDRFGLNPAAHTPETASA
HHHHHHHHHHCCCCCCEECCCCCHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA