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The map label for this gene is groES

Identifier: 220904815

GI number: 220904815

Start: 1854032

End: 1854319

Strand: Direct

Name: groES

Synonym: Ddes_1547

Alternate gene names: 220904815

Gene position: 1854032-1854319 (Clockwise)

Preceding gene: 220904814

Following gene: 220904816

Centisome position: 64.52

GC content: 55.56

Gene sequence:

>288_bases
ATGAAGCTGAAACCCCTTAACGACCGTGTCCTGGTCAAACGCCTTGAAACCGAAGAAAAGACCGCTGGCGGCCTGTATAT
CCCTGATACGGCTAAAGAAAAGCCTTCCAAGGGTCAGGTTGTGGCTGTGGGTCCCGGCAAGGTAGGGGATAATGGCGAGC
GCACTGCCCTGGCTGTGAAAGCCGGCGACGAAGTGCTCTTCAACAAGTACGCCGGAACCGAGGTGAAGCTCGACGGCGTT
GACCATCTGGTCATGCGCGAAGAAGATATCCTCGCCATCATCGACTAA

Upstream 100 bases:

>100_bases
CTACGGCCTGTACGCGCAATATTTTCGGCGCAGACGCCGTACCGCGTCCGTTGCCGTGTCCCACGGGACAATAATAACAT
TTCCGGGAGGATCTGACGTC

Downstream 100 bases:

>100_bases
CTCCCACCTTTGCCGAATTACCACTAGGAGGAAATGTCCCAATGTCTGCTAAAGAAATCTTTTTTGACGTTAAAGCCCGC
GAAAAACTTTCCCGCGGTGT

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10

Number of amino acids: Translated: 95; Mature: 95

Protein sequence:

>95_residues
MKLKPLNDRVLVKRLETEEKTAGGLYIPDTAKEKPSKGQVVAVGPGKVGDNGERTALAVKAGDEVLFNKYAGTEVKLDGV
DHLVMREEDILAIID

Sequences:

>Translated_95_residues
MKLKPLNDRVLVKRLETEEKTAGGLYIPDTAKEKPSKGQVVAVGPGKVGDNGERTALAVKAGDEVLFNKYAGTEVKLDGV
DHLVMREEDILAIID
>Mature_95_residues
MKLKPLNDRVLVKRLETEEKTAGGLYIPDTAKEKPSKGQVVAVGPGKVGDNGERTALAVKAGDEVLFNKYAGTEVKLDGV
DHLVMREEDILAIID

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family

Homologues:

Organism=Homo sapiens, GI4504523, Length=90, Percent_Identity=45.5555555555556, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1790585, Length=96, Percent_Identity=46.875, Blast_Score=86, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17555568, Length=92, Percent_Identity=41.304347826087, Blast_Score=74, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6324594, Length=91, Percent_Identity=45.0549450549451, Blast_Score=79, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21358317, Length=93, Percent_Identity=43.010752688172, Blast_Score=71, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21356029, Length=94, Percent_Identity=41.4893617021277, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): CH10_DESDA (B8J122)

Other databases:

- EMBL:   CP001358
- RefSeq:   YP_002480127.1
- GeneID:   7285245
- GenomeReviews:   CP001358_GR
- KEGG:   dds:Ddes_1547
- HOGENOM:   HBG703377
- ProtClustDB:   PRK00364
- GO:   GO:0005737
- HAMAP:   MF_00580
- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032
- Gene3D:   G3DSA:2.30.33.40
- PANTHER:   PTHR10772
- PRINTS:   PR00297
- SMART:   SM00883

Pfam domain/function: PF00166 Cpn10; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 10274; Mature: 10274

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKPLNDRVLVKRLETEEKTAGGLYIPDTAKEKPSKGQVVAVGPGKVGDNGERTALAVK
CCCCCCCCCEEEEECCCCCCCCCCEECCCCCCCCCCCCCEEEECCCCCCCCCCEEEEEEE
AGDEVLFNKYAGTEVKLDGVDHLVMREEDILAIID
CCCEEEEECCCCCEEEECCCCEEEECCCCEEEEEC
>Mature Secondary Structure
MKLKPLNDRVLVKRLETEEKTAGGLYIPDTAKEKPSKGQVVAVGPGKVGDNGERTALAVK
CCCCCCCCCEEEEECCCCCCCCCCEECCCCCCCCCCCCCEEEECCCCCCCCCCEEEEEEE
AGDEVLFNKYAGTEVKLDGVDHLVMREEDILAIID
CCCEEEEECCCCCEEEECCCCEEEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA