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The map label for this gene is aegA [H]

Identifier: 220904811

GI number: 220904811

Start: 1845338

End: 1847194

Strand: Direct

Name: aegA [H]

Synonym: Ddes_1543

Alternate gene names: 220904811

Gene position: 1845338-1847194 (Clockwise)

Preceding gene: 220904810

Following gene: 220904812

Centisome position: 64.22

GC content: 61.71

Gene sequence:

>1857_bases
ATGCCTGCAATGGATACGTGGAGAGGACAAAAAAACAGCGAAGGCCTGCGGGCTTTTATGGGCTGGGGCGGCCTTGTCGT
CAGCGATGAGACTGTCGATGTGCTCGACATGCTGCGCGCCTATTATGAGGGCGCGGCAGCCGAGTCCTGTGGGCAATGCT
TTCCTTGCCGCAGCGGCCTGAAGCGCATTGCCGAGCGCCTTGATTCGCTTTGCCGCGGCAAAGCCCGGCCAGACGACCGC
GAATACCTGCAGGAACTGGCAGCCCTGGTATACGACAGCGCCCGCTGCGACATCGGACAGACCTCGCCGCAGCCTCTGCT
GGATGTACTGGCCCATGCCCCGCATCTGCTGGAAGCCAGAACAACGGTACGCGGCACCTATACCAGCCTTGTCACGGCGC
CCTGCATCAATGCCTGCCCCGGGCATGTGAAAGTGCCGGACTATATTGAAGAAATCCGCTTTCGCCGCTTTCGCAAGGGG
CTTGACCAGGTTATGCGCAACTGCCCCATGCCCGGCACCATCGGCCGGGTGTGCGAACGCCCCTGCGAAACCGCCTGCAA
ACGCGGTCTCAAGGGCGCGCCGGTGGCCATACGCAATCTCAAGCGCTTTCTGCATGACCACAACGCAAAACGTAATCCGC
TGCCCGAGCCGCAATGCCCGCCGGAAAATGCCAGAAAGGTCGCCATCATCGGCGGCGGCCCAGCCGGTTTGTCCTGCGCT
TACTACCTTGCGCAGCTTGGCCTTGCACCCACCATTTTTGACCGGCATGAAGTTTGCGGCGGCATGGCGAAGTTCGGCAT
CCCCGATTTTCGCCTGCCGCCCTCCGTACTGGCGCGCGAAGTCAGCGTGGCCGTCTCCGGCGGCGGAGAAATCCGCAACG
GCATTGAGATCGGCCGGGACATCACCCTGGACGAACTGCACGATGAAGGCTTCGAGGCCGTCTTTATCGCCACGGGCGCT
CCTCACGCACCGGGCATGCGCTGCGAAGGCGAAGAAAACTGCCCCCTGGGTTACCTCAGCGGTATTCATTACCTGCATGA
AGCCACGCTGGGCAGGCGGCCCGTAAGCGGTACCCGCCTCGTGGTTGTGGGCGGCGGCAACGTGGCAATGGACTGCGCGC
GCACAGCCCTGCGGCACGGCTTCAAGGAAGTGTACGTGGTCTACCGCCGCACCGAAGAAGAAATGCCCGCCGATCCGGTA
GAAGTGGCAGAAGCCAGAGAAGAAGGCGCACTCTTTACCTTCCTGGCTGCGCCCATCCGCATCGAAAGCAGGGACGGACG
CGTCAGCGGCCTTGTCTGCCAGAAAATGGAACTGGGCGCTGCAGATGCCTCCGGCAGACGCCGCCCCGTGCCGGTGAAAG
GGGCTGTTTTTGAAATGCCGTGCGATGCGATTGTTTACGCCATCGGGCAAAAGGTTGCCCTTGAGGTTGTTCTCAAAGGC
AAAGACGGCGCCCTGAACAAATACAATACGCTGGATGCCCACGAAATTACCGGCGAGGTCAGTGCCCTGCCCCGTATTTT
TGGCGGTGGAGACTGCGTAACCGGGCCAAGCTCGCTTATTGCCGCTCTGGCGGCGGGCAAGCGTGCCGCTGCCCACATAG
CCGCCCACCTTAACGGCACGGCGCAGGGGCCTTCGCCCAAAGAAAAGCTGGAACACATGCTCATGCAGATGAACATGCTG
GATACGAAAGAAACTCCCCTGGAAGATCCCACACCGCTCATGCCCATTCATGCCATCCCGGTGCAGGAGCGGCTGCAAGG
TTTTACAGAGGTGGAAACAGATCCGCTGGAATGGGAGGCAGTGCGCGAATCGTCCCGCTGCCTGCGCTGCCTGCGGCTCG
TTATGGCGGCCACCTGA

Upstream 100 bases:

>100_bases
GGCACACATTTTGGGGGAAACCACCAGCCTTTGCATATGCCTGCCAATACGCTACCATACGGCAGGCATAGAATGAGCGG
AAAAACGCGGGAGGCATGCC

Downstream 100 bases:

>100_bases
TCGGCCCTGGTTGCATATCAGGAGCCTGACCGGCAGTATGCGCGGCCATCATTGCCCGCACATGTCATGACCGGGCATGA
TCTTGTTGCCGTAGCTGTTG

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 618; Mature: 617

Protein sequence:

>618_residues
MPAMDTWRGQKNSEGLRAFMGWGGLVVSDETVDVLDMLRAYYEGAAAESCGQCFPCRSGLKRIAERLDSLCRGKARPDDR
EYLQELAALVYDSARCDIGQTSPQPLLDVLAHAPHLLEARTTVRGTYTSLVTAPCINACPGHVKVPDYIEEIRFRRFRKG
LDQVMRNCPMPGTIGRVCERPCETACKRGLKGAPVAIRNLKRFLHDHNAKRNPLPEPQCPPENARKVAIIGGGPAGLSCA
YYLAQLGLAPTIFDRHEVCGGMAKFGIPDFRLPPSVLAREVSVAVSGGGEIRNGIEIGRDITLDELHDEGFEAVFIATGA
PHAPGMRCEGEENCPLGYLSGIHYLHEATLGRRPVSGTRLVVVGGGNVAMDCARTALRHGFKEVYVVYRRTEEEMPADPV
EVAEAREEGALFTFLAAPIRIESRDGRVSGLVCQKMELGAADASGRRRPVPVKGAVFEMPCDAIVYAIGQKVALEVVLKG
KDGALNKYNTLDAHEITGEVSALPRIFGGGDCVTGPSSLIAALAAGKRAAAHIAAHLNGTAQGPSPKEKLEHMLMQMNML
DTKETPLEDPTPLMPIHAIPVQERLQGFTEVETDPLEWEAVRESSRCLRCLRLVMAAT

Sequences:

>Translated_618_residues
MPAMDTWRGQKNSEGLRAFMGWGGLVVSDETVDVLDMLRAYYEGAAAESCGQCFPCRSGLKRIAERLDSLCRGKARPDDR
EYLQELAALVYDSARCDIGQTSPQPLLDVLAHAPHLLEARTTVRGTYTSLVTAPCINACPGHVKVPDYIEEIRFRRFRKG
LDQVMRNCPMPGTIGRVCERPCETACKRGLKGAPVAIRNLKRFLHDHNAKRNPLPEPQCPPENARKVAIIGGGPAGLSCA
YYLAQLGLAPTIFDRHEVCGGMAKFGIPDFRLPPSVLAREVSVAVSGGGEIRNGIEIGRDITLDELHDEGFEAVFIATGA
PHAPGMRCEGEENCPLGYLSGIHYLHEATLGRRPVSGTRLVVVGGGNVAMDCARTALRHGFKEVYVVYRRTEEEMPADPV
EVAEAREEGALFTFLAAPIRIESRDGRVSGLVCQKMELGAADASGRRRPVPVKGAVFEMPCDAIVYAIGQKVALEVVLKG
KDGALNKYNTLDAHEITGEVSALPRIFGGGDCVTGPSSLIAALAAGKRAAAHIAAHLNGTAQGPSPKEKLEHMLMQMNML
DTKETPLEDPTPLMPIHAIPVQERLQGFTEVETDPLEWEAVRESSRCLRCLRLVMAAT
>Mature_617_residues
PAMDTWRGQKNSEGLRAFMGWGGLVVSDETVDVLDMLRAYYEGAAAESCGQCFPCRSGLKRIAERLDSLCRGKARPDDRE
YLQELAALVYDSARCDIGQTSPQPLLDVLAHAPHLLEARTTVRGTYTSLVTAPCINACPGHVKVPDYIEEIRFRRFRKGL
DQVMRNCPMPGTIGRVCERPCETACKRGLKGAPVAIRNLKRFLHDHNAKRNPLPEPQCPPENARKVAIIGGGPAGLSCAY
YLAQLGLAPTIFDRHEVCGGMAKFGIPDFRLPPSVLAREVSVAVSGGGEIRNGIEIGRDITLDELHDEGFEAVFIATGAP
HAPGMRCEGEENCPLGYLSGIHYLHEATLGRRPVSGTRLVVVGGGNVAMDCARTALRHGFKEVYVVYRRTEEEMPADPVE
VAEAREEGALFTFLAAPIRIESRDGRVSGLVCQKMELGAADASGRRRPVPVKGAVFEMPCDAIVYAIGQKVALEVVLKGK
DGALNKYNTLDAHEITGEVSALPRIFGGGDCVTGPSSLIAALAAGKRAAAHIAAHLNGTAQGPSPKEKLEHMLMQMNMLD
TKETPLEDPTPLMPIHAIPVQERLQGFTEVETDPLEWEAVRESSRCLRCLRLVMAAT

Specific function: Unknown

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI119943098, Length=459, Percent_Identity=26.1437908496732, Blast_Score=139, Evalue=1e-32,
Organism=Escherichia coli, GI1788811, Length=417, Percent_Identity=35.0119904076739, Blast_Score=230, Evalue=2e-61,
Organism=Escherichia coli, GI87082180, Length=418, Percent_Identity=35.6459330143541, Blast_Score=223, Evalue=4e-59,
Organism=Escherichia coli, GI1789606, Length=430, Percent_Identity=33.953488372093, Blast_Score=222, Evalue=7e-59,
Organism=Escherichia coli, GI1789243, Length=413, Percent_Identity=32.9297820823245, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI1788468, Length=414, Percent_Identity=29.2270531400966, Blast_Score=152, Evalue=8e-38,
Organism=Caenorhabditis elegans, GI71984108, Length=431, Percent_Identity=28.0742459396752, Blast_Score=141, Evalue=9e-34,
Organism=Caenorhabditis elegans, GI17570289, Length=443, Percent_Identity=24.8306997742664, Blast_Score=127, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6320030, Length=450, Percent_Identity=27.5555555555556, Blast_Score=143, Evalue=6e-35,
Organism=Drosophila melanogaster, GI28574881, Length=449, Percent_Identity=25.8351893095768, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24665539, Length=449, Percent_Identity=25.8351893095768, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24665547, Length=450, Percent_Identity=25.7777777777778, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24665543, Length=450, Percent_Identity=25.7777777777778, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24640763, Length=428, Percent_Identity=25.9345794392523, Blast_Score=136, Evalue=5e-32,
Organism=Drosophila melanogaster, GI18858217, Length=428, Percent_Identity=25.9345794392523, Blast_Score=136, Evalue=5e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR013027
- InterPro:   IPR012285
- InterPro:   IPR006006 [H]

Pfam domain/function: PF00037 Fer4; PF07992 Pyr_redox_2 [H]

EC number: NA

Molecular weight: Translated: 67044; Mature: 66913

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00645 COMPLEX1_51K_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAMDTWRGQKNSEGLRAFMGWGGLVVSDETVDVLDMLRAYYEGAAAESCGQCFPCRSGL
CCCCCCCCCCCCCHHHHHHHCCCCEEECCCHHHHHHHHHHHHCCCCHHHHCCCCHHHHHH
KRIAERLDSLCRGKARPDDREYLQELAALVYDSARCDIGQTSPQPLLDVLAHAPHLLEAR
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCHHHHHH
TTVRGTYTSLVTAPCINACPGHVKVPDYIEEIRFRRFRKGLDQVMRNCPMPGTIGRVCER
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
PCETACKRGLKGAPVAIRNLKRFLHDHNAKRNPLPEPQCPPENARKVAIIGGGPAGLSCA
HHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHH
YYLAQLGLAPTIFDRHEVCGGMAKFGIPDFRLPPSVLAREVSVAVSGGGEIRNGIEIGRD
HHHHHHCCCCHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHEEECCCCHHHHHHHHCCC
ITLDELHDEGFEAVFIATGAPHAPGMRCEGEENCPLGYLSGIHYLHEATLGRRPVSGTRL
CCHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEE
VVVGGGNVAMDCARTALRHGFKEVYVVYRRTEEEMPADPVEVAEAREEGALFTFLAAPIR
EEECCCCHHHHHHHHHHHHCHHHHHHHHHHCHHCCCCCHHHHHHHHHCCCEEEEEECCEE
IESRDGRVSGLVCQKMELGAADASGRRRPVPVKGAVFEMPCDAIVYAIGQKVALEVVLKG
EECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCHHHHHHHHCCCEEEEEEEEC
KDGALNKYNTLDAHEITGEVSALPRIFGGGDCVTGPSSLIAALAAGKRAAAHIAAHLNGT
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCC
AQGPSPKEKLEHMLMQMNMLDTKETPLEDPTPLMPIHAIPVQERLQGFTEVETDPLEWEA
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCHHHHHCCHHHCCCCCCHHHH
VRESSRCLRCLRLVMAAT
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PAMDTWRGQKNSEGLRAFMGWGGLVVSDETVDVLDMLRAYYEGAAAESCGQCFPCRSGL
CCCCCCCCCCCCHHHHHHHCCCCEEECCCHHHHHHHHHHHHCCCCHHHHCCCCHHHHHH
KRIAERLDSLCRGKARPDDREYLQELAALVYDSARCDIGQTSPQPLLDVLAHAPHLLEAR
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCHHHHHH
TTVRGTYTSLVTAPCINACPGHVKVPDYIEEIRFRRFRKGLDQVMRNCPMPGTIGRVCER
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
PCETACKRGLKGAPVAIRNLKRFLHDHNAKRNPLPEPQCPPENARKVAIIGGGPAGLSCA
HHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHH
YYLAQLGLAPTIFDRHEVCGGMAKFGIPDFRLPPSVLAREVSVAVSGGGEIRNGIEIGRD
HHHHHHCCCCHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHEEECCCCHHHHHHHHCCC
ITLDELHDEGFEAVFIATGAPHAPGMRCEGEENCPLGYLSGIHYLHEATLGRRPVSGTRL
CCHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEE
VVVGGGNVAMDCARTALRHGFKEVYVVYRRTEEEMPADPVEVAEAREEGALFTFLAAPIR
EEECCCCHHHHHHHHHHHHCHHHHHHHHHHCHHCCCCCHHHHHHHHHCCCEEEEEECCEE
IESRDGRVSGLVCQKMELGAADASGRRRPVPVKGAVFEMPCDAIVYAIGQKVALEVVLKG
EECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCHHHHHHHHCCCEEEEEEEEC
KDGALNKYNTLDAHEITGEVSALPRIFGGGDCVTGPSSLIAALAAGKRAAAHIAAHLNGT
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCC
AQGPSPKEKLEHMLMQMNMLDTKETPLEDPTPLMPIHAIPVQERLQGFTEVETDPLEWEA
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCHHHHHCCHHHCCCCCCHHHH
VRESSRCLRCLRLVMAAT
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8955321; 9205837; 9278503 [H]